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deferoxamine and Meningitis, Pneumococcal

deferoxamine has been researched along with Meningitis, Pneumococcal in 3 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Meningitis, Pneumococcal: An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)

Research Excerpts

ExcerptRelevanceReference
"Pneumococcal meningitis is associated with the highest fatality case ratios in the world."1.38Antioxidant treatment prevents cognitive impairment and oxidative damage in pneumococcal meningitis survivor rats. ( Barichello, T; Comim, CM; Dal-Pizzol, F; Generoso, JS; Michelon, CM; Mina, F; Otaran, P; Quevedo, J; Santos, AL; Savi, GD; Steckert, AV, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barichello, T1
Santos, AL1
Savi, GD1
Generoso, JS1
Otaran, P1
Michelon, CM1
Steckert, AV1
Mina, F1
Comim, CM1
Dal-Pizzol, F1
Quevedo, J1
Auer, M1
Pfister, LA1
Leppert, D1
Täuber, MG1
Leib, SL1
Pfister, HW1
Koedel, U1
Lorenzl, S1
Tomasz, A1

Other Studies

3 other studies available for deferoxamine and Meningitis, Pneumococcal

ArticleYear
Antioxidant treatment prevents cognitive impairment and oxidative damage in pneumococcal meningitis survivor rats.
    Metabolic brain disease, 2012, Volume: 27, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Behavior, Animal; Cerebral Cortex; Cognit

2012
Effects of clinically used antioxidants in experimental pneumococcal meningitis.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Deferoxamine; Disease Models, Animal; Meningitis, Pneumococca

2000
Antioxidants attenuate microvascular changes in the early phase of experimental pneumococcal meningitis in rats.
    Stroke, 1992, Volume: 23, Issue:12

    Topics: Animals; Antioxidants; Body Water; Brain; Cell Wall; Cerebrovascular Circulation; Deferoxamine; Free

1992