Lower Urinary Tract Symptom

Symptoms of disorders of the lower urinary tract including frequency, NOCTURIA; urgency, incomplete voiding, and URINARY INCONTINENCE. They are often associated with OVERACTIVE BLADDER; URINARY INCOMPETENCE; and INTERSTITIAL CYSTITIS. Lower urinary tract symptoms in males were traditionally called PROSTATISM.

Synonym
Lower Urinary Tract Symptom
Lower Urinary Tract Symptoms

Excerpt	Reference
"Lower urinary tract symptoms are highly prevalent in patients with advanced PD."	( Nielsen, KK; Winge, K, 2012)
"Lower urinary tract symptoms are prevalent in the general adolescent population."	( Hong, YL; Lai, PT; Lee, WM; Ng, CF; Pang, KK; Tam, YH; Wong, YS, 2016)
"Lower urinary tract symptoms are not independently associated with multiple measures of kidney dysfunction or prevalence of chronic kidney disease among older community dwelling men."	( Bauer, SR; Breyer, BN; Kenfield, SA; Marshall, LM; Scherzer, R; Shlipak, M; Zhao, S, 2020)
"Lower urinary tract symptoms are highly prevalent and significantly affect quality of life."	( Bruschini, H; de Bessa, J; Gomes, CM; Hisano, M; Nahas, WC; Sammour, ZM; Srougi, M, 2021)

Excerpt	Reference
"Male lower urinary tract symptoms have been correlated with an increased risk of death; however, it is unclear if treatment will reduce this risk."	( McClure, JA; Welk, B, 2023)

Excerpt	Reference
"Tadalafil is being investigated for the treatment of lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH-LUTS)."	( Casabé, AR; Kim, ED; Mirone, V; Porst, H; Secrest, RJ; Sundin, DP; Viktrup, L; Xu, L, 2011)
"Changes of lower urinary tract symptoms after the treatment were analyzed for one consecutive year using international prostate symptom score, quality of life (QOL) score and uroflowmetry."	( Hashida, I; Hosaka, N; Iijima, K; Kamigaito, T; Nishizawa, S; Okaneya, T; Yamagishi, T, 2012)
"Treatment with tadalafil once daily for lower urinary tract symptoms secondary to clinical benign prostatic hyperplasia showed no negative impact on bladder function as measured by detrusor pressure at maximum urinary flow rate or on any other urodynamic parameter assessed."	( Dmochowski, R; Kaminetsky, J; Klise, S; Kraus, S; Roehrborn, C; Xu, L, 2013)
"In men with lower urinary tract symptoms (LUTS), and in whom the presence of benign prostatic enlargement (BPE) was implicated, propiverine administered as add-on therapy to an α(1)-adrenoceptor antagonist demonstrated similar or superior efficacy to that achieved with an α(1)-adrenoceptor antagonist alone, and combination therapy was particularly effective in patients with urinary storage symptoms."	( McKeage, K, 2013)
"Storage symptoms are often undertreated in men with lower urinary tract symptoms (LUTS)."	( Angulo, JC; Garcia-Hernandez, A; Haab, F; Katona, F; Klaver, M; Oelke, M; Traudtner, K; Van Kerrebroeck, P; Vik, V, 2013)
"The efficacy of silodosin for treating lower urinary tract symptoms was validated according to the total scores of all four questionnaires weighted equally (P < 0."	( Ito, H; Ogawa, T; Sano, F; Yao, M, 2014)
"Medical treatment for men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia is 5α-reductase inhibitor monotherapy or coadministration with an α-blocker."	( Casabé, A; Da Pozzo, LF; Henderson, RJ; Henneges, C; Roehrborn, CG; Sorsaburu, S; Viktrup, L; Wong, DG; Zepeda, S, 2014)
"HoLEP for the treatment of lower urinary tract symptoms (LUTS) in selectively chosen men with known PCa can safely improve urination."	( Frank, I; Krambeck, AE; Rangel, LJ; Rivera, ME; Viers, BR, 2014)
"Several drugs, currently used to treat lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), can be associated with bothersome sexual side effects, including ejaculatory dysfunction (EjD)."	( Carini, M; Corona, G; Ficarra, V; Gacci, M; Maggi, M; Novara, G; Sebastianelli, A; Serni, S; Shariat, SF; Zattoni, F, 2014)
"Phytotherapy has been used to treat patients with lower urinary tract symptoms (LUTS)."	( Allegro, R; Arnone, S; Blefari, F; Carini, M; Cimino, S; Collura, Z; Fragalà, E; Gentile, M; Giannantoni, A; Ginepri, A; Minervini, A; Morgia, G; Palmieri, F; Pareo, RM; Russo, GI; Salvia, G; Santelli, G; Vespasiani, G; Voce, S, 2014)
"Men reporting mixed storage and voiding lower urinary tract symptoms (LUTS) often experience persisting storage LUTS after initial treatment."	( Drake, MJ; Pandian, S; Romancik, M, 2014)
"Treatment of male lower urinary tract symptoms (LUTS) has traditionally focused on the management of benign prostatic obstruction, but the contribution of bladder dysfunction has been recently recognized."	( Dimitropoulos, K; Gravas, S, 2015)
"Studies of men with baseline mild lower urinary tract symptoms demonstrated either no change or an improvement in symptoms after treatment."	( Canto, A; Doersch, K; Kathrins, M; Niederberger, C; Nimeh, T; Seftel, A, 2016)
"However, an improvement in storage lower urinary tract symptoms is mainly responsible for improved bother and quality of life during treatment."	( Baygani, S; Clouth, J; Donatucci, CF; Henneges, C; McVary, KT; Oelke, M; Peterson, A; Wong, D, 2016)
"Most surgical treatments for male lower urinary tract symptoms and benign prostatic hyperplasia affect erectile and ejaculatory functions negatively, leading to patient dissatisfaction."	( Beahrs, JR; Cantrill, CH; Cowan, BE; Dixon, CM; Gange, SN; Gittelman, MC; Goldberg, KA; Kaminetsky, J; Larson, TR; Levin, RM; McVary, KT; Mynderse, LA; Patel, K; Roehrborn, CG; Rousseau, M; Shore, ND; Ulchaker, JC, 2016)
"We compared the effects on lower urinary tract symptoms and bladder outlet obstruction of combination therapy with α1-blocker and 5α-reductase inhibitor or a switch to 5α-reductase inhibitor monotherapy."	( Funahashi, Y; Gotoh, M; Kato, M; Majima, T; Matsukawa, Y; Takai, S; Yamamoto, T, 2017)
"A total of 140 outpatients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia received combination therapy with silodosin 8 mg per day and dutasteride 0."	( Funahashi, Y; Gotoh, M; Kato, M; Majima, T; Matsukawa, Y; Takai, S; Yamamoto, T, 2017)
"Since the patient wanted both his lower urinary tract symptoms and his prostate cancer to be treated together, he decided to undergo robot-assisted radical prostatectomy."	( van Moorselaar, RJA; van Waesberghe, JHTM; Vis, AN, 2017)
"Treating male lower urinary tract symptoms (LUTS) by targeting the prostate would have limited effect on overactive bladder (OAB) symptoms."	( Henningsohn, L; Jacobsen, JL; Kilany, S; Svensson, M, 2017)
"To study nocturia in patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) after medical or placebo treatment."	( Bi, J; Jiang, Y; Lin, Y; Wei, N; Xue, Z, 2018)
"Eighty untreated outpatients with lower urinary tract symptoms (LUTS) due to BOO received 5 mg tadalafil daily for 12 months."	( Funahashi, Y; Gotoh, M; Inoue, S; Kanada, Y; Kato, M; Majima, T; Matsukawa, Y; Takai, S; Yamamoto, T, 2020)
"The treatment options for male lower urinary tract symptoms (LUTS) widely range from self-monitoring to oral medications to surgical procedures."	( Brunocilla, E; Cindolo, L; Corsi, P; D'Agostino, D; Del Rosso, A; Giampaoli, M; Mineo Bianchi, F; Porreca, A; Romagnoli, D; Sadini, P; Schiavina, R, 2019)
"Inclusion criteria were lower urinary tract symptoms refractory to medical therapy, maximum urinary flow rate (Qmax) ≤15 mL/s, International Prostate Symptom Score (IPSS) ≥8 and absolute indications for surgery."	( Carcano, G; Castellani, D; Dellabella, M; Di Rosa, M; Gasparri, L; Pirola, GM; Pucci, M; Saredi, G, 2019)
"Treatment for lower urinary tract symptoms (LUTS) is often delayed, as it is considered a natural progression of aging."	( Gittelman, M; Lowe, FC; Roehrborn, CG; Verbeek, AE; Wruck, JM, 2019)
"Men with lower urinary tract symptoms (LUTS) treated with α-blockers (eg, tamsulosin) may experience overactive bladder (OAB) symptoms and receive add-on antimuscarinics."	( Jong, JJ; Kakizaki, H; Katou, D; Lee, KS; Sumarsono, B; Uno, S; Yamaguchi, O; Yamamoto, O, 2020)
"Male patients with lower urinary tract symptoms (50 to 89 years), with remaining OAB symptoms even after administering tadalafil for more than 8 weeks were randomly assigned to either tadalafil monotherapy group (5 mg/day) or tadalafil/mirabegron combination therapy group (5 mg/50 mg/day)."	( Fuse, M; Kaga, K; Kageyama, S; Sakata, K; Tokunaga, S; Yamanishi, T; Yokoyama, T, 2020)
"We assessed whether treating lower urinary tract symptoms with dutasteride altered either nocturia or sleep quality using data from REDUCE."	( Andriole, GL; Bliwise, DL; Fischer, SC; Freedland, SJ; Hopp, ML; Howard, LE; Kuhlmann, PK; Moreira, DM; Roehrborn, CG, 2021)
"Combination drug therapy for lower urinary tract symptoms (LUTS) is beneficial to selected patients and recommended by guidelines."	( Ali, M; Choudhury, N; Covernton, PJO; Fatoye, F; Jaggi, A; Landeira, M; van Maanen, R, 2021)
"The current armamentarium of drugs for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) is diverse and includes both monotherapy and combination therapy."	( Bernikov, AN; Loran, OB; Pushkar, DY, 2022)
"The first-line drug treatment for lower urinary tract symptoms, orally administered antimuscarinics, fails to reach the equilibrium dissociation constant of muscarinic receptors even at their maximum plasma concentration and tends to evoke a half-maximal response at a muscarinic receptor occupancy of just 0."	( Beckel, J; Chancellor, M; Chermansky, C; Cho, KJ; Ganguly, A; Hashimoto, M; Kanai, A; Kaufman, J; Tyagi, P; Tyagi, S; Yoshimura, N, 2023)
"Male lower urinary tract symptoms have been correlated with an increased risk of death; however, it is unclear if treatment will reduce this risk."	( McClure, JA; Welk, B, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	573 (71.89)	28.8240
2020's	224 (28.11)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	medium	1	1
ammonium hydroxide	medium	1	1
methane	medium	1	1
citric acid, anhydrous	medium	1	1
hippuric acid	low	1	0
lactic acid	low	1	0
glycerol	medium	1	1
histamine	medium	1	1
hydrogen	medium	1	1
racemethionine	low	1	0
nitrates	medium	1	1
nitric acid	low	1	0
nitrites	medium	2	1
propylene glycol	medium	1	1
pyruvic acid	low	1	0
sulfur dioxide	medium	1	1
uric acid	low	1	0
alfuzosin	medium	14	4
aspirin	medium	1	1
benzothiazide	medium	1	1
berberine	low	1	0
bethanechol	low	1	0
bicalutamide	medium	6	3
caffeine	low	5	0
celecoxib	medium	2	2
chlorthalidone	low	1	0
doxazosin	medium	27	13
felodipine	low	1	0
fluconazole	low	1	0
flutamide	medium	1	1
gentamicin	medium	1	1
ibuprofen	medium	1	1
lidocaine	medium	2	2
imipramine	low	1	0
isoflurane	medium	1	1
ketamine	medium	36	2
losartan	low	1	0
memantine	medium	1	1
mepivacaine	low	1	0
methadone	medium	1	1
methyl salicylate	medium	1	1
naftopidil	medium	11	4
nitroglycerin	medium	1	1
oxybutynin	medium	6	1
papaverine	low	1	0
potassium chloride	low	1	0
prazosin	medium	3	1
procarbazine	low	1	0
propiverine	medium	3	1
terazosin	medium	2	1
thalidomide	low	1	0
urapidil	medium	1	1
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	low	1	0
corticosterone	low	1	0
estriol	medium	1	1
carbachol	low	3	0
prednisone	low	3	0
dehydroepiandrosterone	low	1	0
ethinyl estradiol	low	1	0
apomorphine	low	1	0
phenylephrine	low	3	0
levodopa	low	2	0
methoxamine	low	1	0
leucine	low	1	0
methacholine chloride	low	1	0
androstenedione	low	1	0
methionine	low	1	0
histidine	medium	1	1
medroxyprogesterone acetate	low	1	0
isoleucine	low	2	0
ethylene	medium	1	1
bisphenol a	low	1	0
isosorbide dinitrate	medium	2	1
quinoxalines	medium	1	1
quinuclidines	medium	14	7
caprolactam	medium	1	1
thiophenes	medium	1	1
isopropyl myristate	medium	1	1
catechin	medium	1	1
quinazolines	medium	16	4
indazoles	low	1	0
benzoxazoles	medium	1	1
thiazoles	medium	28	13
betamethasone	medium	1	1
phenylpropanolamine	low	3	0
hematoxylin	low	1	0
dihydrotestosterone	medium	5	2
methamphetamine	low	3	0
muscone	medium	1	1
malondialdehyde	low	1	0
eosine yellowish-(ys)	low	1	0
dehydroepiandrosterone sulfate	low	1	0
levonorgestrel	low	2	0
deoxycytidine	medium	1	1
mesterolone	low	1	0
1,2-epoxyhexane	medium	1	1
dronabinol	low	3	0
ethamsylate	low	1	0
mannose	medium	1	1
enbucrilate	low	1	0
silver	medium	1	1
thulium	medium	16	5
titanium	medium	1	1
holmium	medium	16	1
uranium	medium	1	1
galactose	medium	1	1
ozone	medium	1	1
isosorbide-5-mononitrate	medium	1	1
4-methoxyamphetamine	low	1	0
androstane-3,17-diol	low	1	0
calcium oxalate	low	1	0
tramadol	medium	1	1
paclitaxel	medium	2	1
etoposide	low	1	0
nicorandil	low	2	0
fomesafen	low	4	0
finasteride	medium	24	7
gemcitabine	medium	1	1
capecitabine	low	1	0
glucose, (beta-d)-isomer	low	1	0
baicalin	medium	1	1
testosterone undecanoate	medium	5	2
lercanidipine	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	1	0
dapoxetine	medium	1	1
voriconazole	medium	1	1
nicotine	medium	2	1
lopinavir	medium	1	1
1,n(6)-ethenoadenine	medium	1	1
thiamethoxam	medium	1	1
tadalafil	medium	119	41
peroxynitrous acid	medium	1	1
imatinib mesylate	medium	1	1
gefitinib	medium	1	1
tamsulosin	medium	132	55
calcium borate	medium	1	1
beta-lactams	low	1	0
docetaxel anhydrous	medium	1	1
levofloxacin	medium	2	2
angiotensin ii	low	2	0
esketamine	low	1	0
solifenacin succinate	medium	38	14
trimethoprim, sulfamethoxazole drug combination	low	1	0
ritonavir	medium	1	1
dihydropyridines	low	1	0
permanganate	medium	1	1
carboplatin	medium	1	1
glycogen	low	1	0
alpha-aminobutyric acid	low	1	0
tretinoin	medium	1	1
resveratrol	low	2	0
retinol	low	1	0
lycopene	medium	4	1
fosfomycin	low	1	0
gamma-sitosterol	low	2	0
2,3-bis(bromomethyl)quinoxaline-1,4-dioxide	medium	1	1
sodium bicarbonate	low	1	0
cannabidiol	low	1	0
leuprolide	low	2	0
curcumin	medium	1	1
secinh3	low	1	0
capsaicin	low	1	0
tamoxifen	low	1	0
nitrogen dioxide	medium	1	1
ospemifene	low	1	0
freedom	low	1	0
nitinol	medium	14	3
cytellin	low	2	0
quercetin	medium	1	1
dinoprostone	low	4	0
cholecalciferol	medium	1	1
humulene	low	2	0
baicalein	medium	1	1
daidzein	medium	1	1
menaquinone 6	medium	1	1
sirolimus	medium	1	1
trospium chloride	medium	1	1
menaquinone 7	medium	1	1
morphine	medium	1	1
istradefylline	low	1	0
deamino arginine vasopressin	medium	10	2
goserelin	medium	7	4
silodosin	medium	61	19
lead	medium	1	1
arsenic	medium	1	1
phosphorus	medium	1	1
pregabalin	medium	1	1
resiniferatoxin	low	1	0
selenium	medium	4	2
imidafenacin	medium	2	2
axitinib	medium	1	1
nitrofurantoin	low	2	0
dutasteride	medium	55	19
fesoterodine	medium	3	2
bay 58-2667	low	1	0
mocetinostat	low	2	0
mirabegron	medium	27	12
sorbitan monooleate	medium	1	1
pitolisant	medium	1	1
tribulus	medium	1	1
phytosterols	low	1	0
lithium borate	low	1	0
glucagon	medium	1	1
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ilys-prolyl-alaninamide	medium	6	3
cellulose	medium	1	1
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one	low	1	0
lm11a-31	low	1	0
chitosan	medium	1	1
trelstar	low	2	0
tolterodine tartrate	medium	13	3
mannans	low	1	0
gw 1000	low	1	0
glycolipids	medium	1	1
piperidines	medium	1	1
interleukin-8	medium	5	2
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine	medium	1	1
heme	medium	1	1
chondroitin	medium	1	1
ascorbic acid	low	2	0
epidermal growth factor	low	1	0
transforming growth factor beta	low	3	0
hyaluronoglucosaminidase	medium	1	1
catalpol	medium	1	1
chondroitin sulfates	medium	2	2
exudates	low	1	0
cyclic gmp	medium	5	1
folic acid	low	1	0
rifampin	low	1	0
dacarbazine	low	1	0
sildenafil citrate	medium	10	2
da 8159	low	1	0
vardenafil dihydrochloride	medium	7	2
8-hydroxy-2'-deoxyguanosine	medium	1	1
mirodenafil	medium	1	1
acetylcellulose	medium	1	1
leptin	low	1	0
pyrimidinones	medium	2	1

Protein Targets (2,025)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
IDH1	22	0	0	22
chromobox protein homolog 1	36	0	0	36
geminin	50	0	0	50
Chain A, HADH2 protein	24	0	0	24
Chain B, HADH2 protein	24	0	0	24
Chain A, 2-oxoglutarate Oxygenase	22	0	0	22
Chain A, Ferritin light chain	11	0	0	11
endonuclease IV	4	0	0	4
glp-1 receptor, partial	13	0	0	13
thioredoxin reductase	32	0	0	32
15-lipoxygenase, partial	14	0	0	14
phosphopantetheinyl transferase	21	0	0	21
ATAD5 protein, partial	18	0	0	18
Fumarate hydratase	15	0	0	15
USP1 protein, partial	31	0	0	31
NFKB1 protein, partial	9	0	0	9
TDP1 protein	56	0	0	56
Microtubule-associated protein tau	31	0	0	31
thioredoxin glutathione reductase	7	0	0	7
Smad3	14	0	0	14
aldehyde dehydrogenase 1 family, member A1	37	0	0	37
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
regulator of G-protein signaling 4	17	0	0	17
EWS/FLI fusion protein	33	0	0	34
nonstructural protein 1	9	0	0	9
estrogen-related nuclear receptor alpha	55	0	0	55
polyprotein	15	0	0	15
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
arylsulfatase A	16	0	0	16
euchromatic histone-lysine N-methyltransferase 2	50	0	0	50
Bloom syndrome protein isoform 1	15	0	0	15
cytochrome P450 2D6 isoform 1	11	0	0	11
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
peripheral myelin protein 22 isoform 1	9	0	0	9
cellular tumor antigen p53 isoform a	12	0	0	12
cytochrome P450 2C19 precursor	11	0	0	11
cytochrome P450 2C9 precursor	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	18	0	0	18
vitamin D3 receptor isoform VDRA	16	0	0	16
mitogen-activated protein kinase 1	21	0	0	21
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
ras-related protein Rab-9A	8	0	0	8
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
DNA polymerase iota isoform a (long)	23	0	0	23
survival motor neuron protein isoform d	21	0	0	21
cytochrome P450 3A4 isoform 1	32	0	0	32
M-phase phosphoprotein 8	11	0	0	11
muscarinic acetylcholine receptor M1	11	0	0	11
lamin isoform A-delta10	40	0	0	40
Gamma-aminobutyric acid receptor subunit pi	32	0	0	32
Polyunsaturated fatty acid lipoxygenase ALOX15B	14	3	0	17
Guanylate cyclase soluble subunit beta-2	0	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	7	1	8
Integrin beta-3	12	2	0	14
Integrin alpha-IIb	12	1	0	13
Gamma-aminobutyric acid receptor subunit beta-1	32	0	0	32
Gamma-aminobutyric acid receptor subunit delta	32	0	0	32
Gamma-aminobutyric acid receptor subunit gamma-2	32	0	0	32
Gamma-aminobutyric acid receptor subunit alpha-5	32	0	0	32
Gamma-aminobutyric acid receptor subunit alpha-3	32	0	0	32
Gamma-aminobutyric acid receptor subunit gamma-1	32	0	0	32
Gamma-aminobutyric acid receptor subunit alpha-2	32	0	0	32
Gamma-aminobutyric acid receptor subunit alpha-4	32	0	0	32
Gamma-aminobutyric acid receptor subunit gamma-3	32	0	0	32
Gamma-aminobutyric acid receptor subunit alpha-6	32	0	0	32
Guanylate cyclase soluble subunit alpha-2	0	0	0	1
Alpha-synuclein	10	8	1	19
Histamine H2 receptor	19	1	1	21
Gamma-aminobutyric acid receptor subunit alpha-1	32	2	0	34
Gamma-aminobutyric acid receptor subunit beta-3	32	0	0	32
Gamma-aminobutyric acid receptor subunit beta-2	32	0	0	32
Guanylate cyclase soluble subunit alpha-1	0	0	0	1
Guanylate cyclase soluble subunit beta-1	0	0	0	1
Histone acetyltransferase p300	0	2	0	2
Hypoxia-inducible factor 1-alpha	0	1	0	1
GABA theta subunit	32	0	0	32
CREB-binding protein	1	2	0	3
Ataxin-2	25	0	0	25
Endothelial PAS domain-containing protein 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	32	0	0	32
ATP-dependent phosphofructokinase	21	0	0	21
5-hydroxytryptamine receptor 2C	0	6	1	7
5-hydroxytryptamine receptor 2A	0	7	2	9
5-hydroxytryptamine receptor 1A	0	10	1	12
5-hydroxytryptamine receptor 1B	0	7	1	8
5-hydroxytryptamine receptor 1D	0	4	1	5
5-hydroxytryptamine receptor 1F	0	4	1	5
5-hydroxytryptamine receptor 2B	0	5	1	6
5-hydroxytryptamine receptor 6	0	2	1	3
Sodium-dependent serotonin transporter	0	14	2	16
Sodium-dependent serotonin transporter	0	5	1	6
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	2	1	3
5-hydroxytryptamine receptor 5B	0	2	1	3
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	2	1	3
PPM1D protein	12	0	0	12
G	31	0	0	31
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	3	5
Interferon beta	38	0	0	38
HLA class I histocompatibility antigen, B alpha chain	31	0	0	31
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	3	3	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	3	5
Serine/threonine-protein kinase mTOR	0	5	4	9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	4	3	7
Rapamycin-insensitive companion of mTOR	0	1	0	1
Regulatory-associated protein of mTOR	0	2	0	2
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	0	1	1
Inositol hexakisphosphate kinase 1	31	0	0	31
Target of rapamycin complex 2 subunit MAPKAP1	0	1	0	1
Target of rapamycin complex subunit LST8	0	2	0	2
cytochrome P450 2C9, partial	31	0	0	31
Chain A, Avidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain B, Avidin	0	0	1	1
Gonadotropin-releasing hormone receptor	0	2	1	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	25	0	0	25
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	51	0	0	51
AR protein	74	0	0	74
nuclear receptor subfamily 1, group I, member 3	38	0	0	38
cytochrome P450 family 3 subfamily A polypeptide 4	43	0	0	43
glucocorticoid receptor [Homo sapiens]	49	0	0	49
pregnane X nuclear receptor	48	0	0	48
estrogen nuclear receptor alpha	79	0	0	79
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	35	0	0	35
nuclear factor erythroid 2-related factor 2 isoform 2	17	0	0	17
heat shock protein beta-1	13	0	0	13
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
Voltage-dependent calcium channel gamma-2 subunit	31	0	0	31
Bile salt export pump	0	61	0	61
Cyclin-dependent kinase 1	0	5	3	8
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	32	0	1	33
Xanthine dehydrogenase/oxidase	0	6	0	6
TAR DNA-binding protein 43	9	0	0	9
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	2	4
ATPase family AAA domain-containing protein 5	20	0	0	20
glucocerebrosidase	13	0	0	13
alpha-galactosidase	6	0	0	6
lysosomal alpha-glucosidase preproprotein	9	0	0	9
flap endonuclease 1	15	0	0	15
Alpha-1A adrenergic receptor	0	6	3	9
Solute carrier family 22 member 1	0	11	0	14
Neuronal acetylcholine receptor subunit alpha-4	3	5	2	11
Neuronal acetylcholine receptor subunit beta-2	3	5	2	11
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Alpha-1A adrenergic receptor	0	7	1	8
Alpha-2B adrenergic receptor	0	11	3	14
Alpha-2C adrenergic receptor	0	10	3	13
Acetylcholinesterase	0	10	0	10
Alpha-2A adrenergic receptor	0	10	3	13
Alpha-1D adrenergic receptor	0	16	3	19
Alpha-1D adrenergic receptor	0	17	3	24
Alpha-1A adrenergic receptor	0	15	7	28
Alpha-1B adrenergic receptor	0	15	6	25
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	25	0	25
Voltage-dependent L-type calcium channel subunit alpha-1C	0	9	0	10
Sodium channel protein type 5 subunit alpha	0	6	0	6
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
acid sphingomyelinase	4	0	0	4
cytochrome P450 2D6	31	0	0	31
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	25	0	0	25
histone acetyltransferase KAT2A isoform 1	11	0	0	11
ATP-binding cassette sub-family C member 3	0	45	0	45
Multidrug resistance-associated protein 4	0	46	0	50
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Potassium channel subfamily K member 2	0	2	3	5
ATP-dependent translocase ABCB1	0	18	3	28
Alpha-2A adrenergic receptor	0	11	2	14
Alpha-2C adrenergic receptor	0	10	1	12
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
5-hydroxytryptamine receptor 6	0	9	0	9
Spike glycoprotein	27	0	4	31
Sodium-dependent dopamine transporter	0	15	0	15
Potassium channel subfamily K member 2	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	45	0	46
interleukin 8	12	0	0	12
acetylcholinesterase	22	0	0	22
SMAD family member 2	21	0	0	21
SMAD family member 3	21	0	0	21
GLI family zinc finger 3	59	0	0	59
estrogen receptor 2 (ER beta)	32	0	0	32
progesterone receptor	38	0	0	38
retinoic acid nuclear receptor alpha variant 1	53	0	0	53
retinoid X nuclear receptor alpha	42	0	0	42
farnesoid X nuclear receptor	33	0	0	33
peroxisome proliferator-activated receptor delta	33	0	0	33
peroxisome proliferator activated receptor gamma	35	0	0	35
vitamin D (1,25- dihydroxyvitamin D3) receptor	34	0	0	34
Histone H2A.x	16	0	0	16
Caspase-7	5	0	0	5
potassium voltage-gated channel subfamily H member 2 isoform d	18	0	0	18
caspase-3	5	0	0	5
thyroid hormone receptor beta isoform 2	50	0	0	50
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	1	3
nuclear factor erythroid 2-related factor 2 isoform 1	48	0	0	48
peripheral myelin protein 22	28	0	0	28
muscleblind-like protein 1 isoform 1	8	0	0	8
neuropeptide S receptor isoform A	7	0	0	7
Sex hormone-binding globulin	0	1	8	9
Beta-glucuronidase	0	2	0	2
Cholinesterase	0	6	0	6
Corticosteroid-binding globulin	0	5	0	5
Aromatase	0	8	0	11
Androgen receptor	0	19	1	20
Gastrin/cholecystokinin type B receptor	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	4	0	4
Nuclear receptor ROR-gamma	20	1	1	22
DNA polymerase kappa isoform 1	20	0	0	20
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	4	2	6
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	4	3	9
Type-2 angiotensin II receptor	0	4	0	4
Type-2 angiotensin II receptor	0	3	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	14	0	0	14
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
Luciferase	23	0	0	23
hypoxia-inducible factor 1 alpha subunit	14	0	0	14
GLS protein	25	0	0	25
aryl hydrocarbon receptor	25	0	0	25
thyroid stimulating hormone receptor	27	0	0	27
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	17	0	0	17
v-jun sarcoma virus 17 oncogene homolog (avian)	24	0	0	24
lethal factor (plasmid)	12	0	0	12
Cellular tumor antigen p53	40	0	0	40
5-hydroxytryptamine receptor 1A	0	5	2	7
Tryptophan 5-hydroxylase 1	0	2	0	2
D(2) dopamine receptor	0	8	2	12
Alpha-1B adrenergic receptor	0	26	3	29
D	0	4	0	4
D(3) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(1A) dopamine receptor	0	7	2	11
D(4) dopamine receptor	0	7	1	9
D(1B) dopamine receptor	0	2	0	3
D(1B) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	5	0	5
D(4) dopamine receptor	0	2	1	3
D(3) dopamine receptor	0	9	2	12
Alpha-1A adrenergic receptor	0	28	4	32
5-hydroxytryptamine receptor 7	0	6	0	6
D(2) dopamine receptor	0	6	3	9
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	1	0	1
D	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	8	1	9
Chain A, Hyaluronidase, phage associated	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Polyphenol oxidase 2	0	3	0	5
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	1	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	5	0	5
Alpha-2B adrenergic receptor	0	11	1	13
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
thyroid stimulating hormone receptor	22	0	0	22
hypothetical protein, conserved	4	0	0	4
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	4
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Epidermal growth factor receptor	0	9	4	13
Carbonic anhydrase 1	0	15	0	21
Carbonic anhydrase 2	0	16	0	23
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	9	2	11
Seed linoleate 13S-lipoxygenase-1	0	4	0	6
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	8	0	9
Adenosine receptor A1	0	8	0	12
Adenosine receptor A2a	0	10	0	15
Substance-P receptor	0	4	0	4
Prostaglandin G/H synthase 2	0	10	3	14
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	8	0	8
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	1	1	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Leukotriene C4 synthase	0	0	2	2
caspase 7, apoptosis-related cysteine protease	13	0	0	13
caspase-3	13	0	0	13
histone deacetylase 9 isoform 3	7	0	0	7
tyrosine-protein kinase Yes	4	0	0	4
Bone morphogenetic protein receptor type-1B	0	0	3	3
Cell division cycle 7-related protein kinase	0	0	3	3
Serine/threonine-protein kinase PLK4	0	2	3	5
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	3	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Pyridoxal kinase	0	0	3	3
Citron Rho-interacting kinase	0	0	3	3
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	2
Peripheral plasma membrane protein CASK	0	0	2	2
Aurora kinase A	0	0	3	3
Cyclin-G-associated kinase	0	1	3	4
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 3	0	0	3	3
Mitogen-activated protein kinase 13	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	1	2	3
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	3	3
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	3	3
NUAK family SNF1-like kinase 1	0	1	2	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	3	3
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	3	3
Serine/threonine-protein kinase ULK1	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	3	3
Ribosomal protein S6 kinase alpha-5	0	0	3	3
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	3	3
Ribosomal protein S6 kinase alpha-4	0	0	3	3
Serine/threonine-protein kinase 16	0	0	3	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	3	3
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	3	3
Serine/threonine-protein kinase D3	0	1	3	4
Cyclin-dependent kinase 14	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase OSR1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	3	3
Serine/threonine-protein kinase LATS1	0	0	3	3
Serine/threonine-protein kinase PAK 4	0	0	3	3
Serine/threonine-protein kinase Chk2	0	0	2	2
Tyrosine-protein kinase ABL1	0	6	4	11
RAF proto-oncogene serine/threonine-protein kinase	0	0	2	2
Receptor tyrosine-protein kinase erbB-2	0	3	2	5
High affinity nerve growth factor receptor	0	0	3	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	3	3
Protein kinase C beta type	0	1	3	4
Insulin receptor	0	1	3	4
Tyrosine-protein kinase Lck	0	4	3	7
Tyrosine-protein kinase Fyn	0	3	3	6
Glycogen phosphorylase, liver form	0	1	3	4
Tyrosine-protein kinase Fes/Fps	0	0	3	3
Macrophage colony-stimulating factor 1 receptor	0	0	2	2
Adenine phosphoribosyltransferase	0	0	3	3
Tyrosine-protein kinase Yes	0	2	3	5
Tyrosine-protein kinase Lyn	0	0	3	3
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	3	5
Insulin-like growth factor 1 receptor	0	1	3	4
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	3	3
Hepatocyte growth factor receptor	0	1	3	4
Tyrosine-protein kinase HCK	0	1	3	4
Cytochrome P450 3A4	0	20	3	26
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Platelet-derived growth factor receptor beta	0	0	3	3
Tyrosine-protein kinase Fgr	0	0	3	3
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	3	3
Cytochrome P450 2D6	0	7	2	9
Mast/stem cell growth factor receptor Kit	0	2	3	5
Glycogen phosphorylase, brain form	0	0	3	3
Breakpoint cluster region protein	0	2	4	7
Serine/threonine-protein kinase pim-1	0	1	4	5
Fibroblast growth factor receptor 1	0	2	3	5
DNA topoisomerase 2-alpha	0	1	4	10
Cyclin-dependent kinase 4	0	1	3	4
ADP/ATP translocase 3	0	0	3	3
Inosine-5'-monophosphate dehydrogenase 2	0	0	3	3
Proto-oncogene tyrosine-protein kinase Src	0	4	3	7
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	3	3
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	2	3	5
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	3	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	4	7
Platelet-derived growth factor receptor alpha	0	1	3	4
Tyrosine-protein kinase Fer	0	0	3	3
Protein kinase C alpha type	0	1	4	5
cAMP-dependent protein kinase catalytic subunit alpha	0	0	3	3
Vascular endothelial growth factor receptor 1	0	2	2	4
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	3	3
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Casein kinase II subunit alpha'	0	3	3	6
Ras-related protein Rab-6A	0	0	3	3
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	3	3
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	1	2	3
Multifunctional protein ADE2	0	0	3	3
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	0	3	3
Ferrochelatase, mitochondrial	0	0	3	3
Ribosomal protein S6 kinase beta-1	0	0	3	3
Tyrosine-protein kinase JAK1	0	0	3	3
Protein kinase C eta type	0	1	2	3
Cyclin-dependent kinase 2	0	2	3	5
Beta-adrenergic receptor kinase 1	0	0	3	3
Probable ATP-dependent RNA helicase DDX6	0	0	3	3
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	0	3	3
MAP/microtubule affinity-regulating kinase 3	0	0	3	3
Deoxycytidine kinase	0	0	3	5
Mitogen-activated protein kinase 1	0	1	3	4
Ephrin type-A receptor 2	0	0	3	3
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	0	3	3
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	3	3
UMP-CMP kinase	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	3	3
Wee1-like protein kinase	0	0	3	3
Heme oxygenase 2	0	0	3	3
Tyrosine-protein kinase receptor UFO	0	1	2	3
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	3	3
DnaJ homolog subfamily A member 1	0	0	3	3
RAC-alpha serine/threonine-protein kinase	0	2	3	5
RAC-beta serine/threonine-protein kinase	0	0	3	3
G protein-coupled receptor kinase 4	0	0	2	2
Dual specificity protein kinase TTK	0	0	3	3
DNA replication licensing factor MCM4	0	0	3	3
Myosin-10	0	0	2	2
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	2	2	4
Vascular endothelial growth factor receptor 2	0	5	2	7
Dual specificity mitogen-activated protein kinase kinase 2	0	0	3	3
Receptor-type tyrosine-protein kinase FLT3	0	2	3	5
Bone morphogenetic protein receptor type-1A	0	0	3	3
Activin receptor type-1B	0	0	3	3
TGF-beta receptor type-1	0	0	3	3
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	3	3
Electron transfer flavoprotein subunit beta	0	0	3	3
Tyrosine-protein kinase CSK	0	0	3	3
Glycine--tRNA ligase	0	0	3	3
Protein kinase C iota type	0	1	3	4
Exosome RNA helicase MTR4	0	0	3	3
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase Tec	0	0	3	3
Tyrosine-protein kinase TXK	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	3	3
Tyrosine-protein kinase FRK	0	0	3	3
G protein-coupled receptor kinase 6	0	1	3	4
Tyrosine-protein kinase ZAP-70	0	0	2	2
Tyrosine-protein kinase SYK	0	1	4	5
26S proteasome regulatory subunit 6B	0	0	3	3
Mitogen-activated protein kinase 8	0	0	3	3
Mitogen-activated protein kinase 9	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Casein kinase I isoform alpha	0	1	3	4
Casein kinase I isoform delta	0	0	3	3
MAP kinase-activated protein kinase 2	0	0	3	3
Cyclin-dependent kinase 8	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	3	3
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	3	3
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	3	3
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Dual specificity protein kinase CLK3	0	0	3	3
Glycogen synthase kinase-3 alpha	0	1	3	4
Glycogen synthase kinase-3 beta	0	2	3	5
Cyclin-dependent kinase 7	0	0	3	3
Cyclin-dependent kinase 9	0	0	3	3
Ras-related protein Rab-27A	0	0	3	3
Tyrosine-protein kinase Blk	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	3	3
Ribosomal protein S6 kinase alpha-3	0	0	3	3
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek2	0	1	3	4
Serine/threonine-protein kinase Nek3	0	0	3	3
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase PLK1	0	5	3	8
Death-associated protein kinase 1	0	3	2	5
LIM domain kinase 1	0	0	3	3
LIM domain kinase 2	0	0	3	3
Mitogen-activated protein kinase 12	0	0	2	2
Mitogen-activated protein kinase 10	0	1	3	4
Tyrosine--tRNA ligase, cytoplasmic	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-1	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	2
Ephrin type-B receptor 3	0	0	3	3
Ephrin type-A receptor 5	0	0	3	3
Ephrin type-B receptor 4	0	1	3	4
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	3	3
Adenylate kinase 2, mitochondrial	0	0	3	3
Adenosine kinase	0	0	3	3
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Ras-related protein Rab-10	0	0	3	3
Cell division control protein 2 homolog	0	0	2	2
Actin-related protein 3	0	0	3	3
Actin-related protein 2	0	0	3	3
Calcium-dependent protein kinase 1	0	0	2	2
GTP-binding nuclear protein Ran	0	0	3	3
Casein kinase II subunit alpha	0	3	2	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase-like 1	0	0	2	2
Cyclin-dependent kinase 6	0	1	3	4
Cyclin-dependent-like kinase 5	0	1	3	4
Cyclin-dependent kinase 16	0	0	3	3
Cyclin-dependent kinase 17	0	0	3	3
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
Protein kinase C epsilon type	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 1	0	1	3	4
Angiopoietin-1 receptor	0	0	2	2
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
DNA topoisomerase 2-beta	0	1	4	11
Protein kinase C theta type	0	1	3	4
Activin receptor type-1	0	0	3	3
Macrophage-stimulating protein receptor	0	0	3	3
Focal adhesion kinase 1	0	1	3	4
Protein kinase C zeta type	0	1	3	4
Protein kinase C delta type	0	1	3	4
Tyrosine-protein kinase BTK	0	0	3	3
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	3	3
Activated CDC42 kinase 1	0	0	3	3
Epithelial discoidin domain-containing receptor 1	0	0	3	3
Tyrosine-protein kinase ITK/TSK	0	0	2	2
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	1	3	4
Serine/threonine-protein kinase 4	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	3	3
Serine/threonine-protein kinase PAK 1	0	2	2	4
Dual specificity mitogen-activated protein kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase 7	0	0	3	3
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 1	0	0	3	3
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	3	3
Rho-associated protein kinase 1	0	0	3	3
Non-receptor tyrosine-protein kinase TNK1	0	0	3	3
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	3	3
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	3	3
Protein-tyrosine kinase 6	0	0	3	3
cGMP-dependent protein kinase 1	0	0	3	3
Cyclin-dependent kinase 13	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	3	3
Protein-tyrosine kinase 2-beta	0	0	3	3
Maternal embryonic leucine zipper kinase	0	0	3	3
Structural maintenance of chromosomes protein 1A	0	0	3	3
Chromodomain-helicase-DNA-binding protein 4	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 1	0	0	3	3
Serine/threonine-protein kinase D1	0	1	2	3
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	2	2
Delta(24)-sterol reductase	0	0	3	3
Ribosomal protein S6 kinase alpha-1	0	0	3	3
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	1	3	4
Mitogen-activated protein kinase 11	0	0	3	3
Serine/threonine-protein kinase STK11	0	0	3	3
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	1	3	4
Serine/threonine-protein kinase N2	0	0	3	3
Mitogen-activated protein kinase 14	0	2	3	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	3	3
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	0	3	3
AP2-associated protein kinase 1	0	0	3	3
Myosin light chain kinase 3	0	0	3	3
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	3	3
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	3	3
Acyl-CoA dehydrogenase family member 10	0	0	3	3
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	3	3
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Uncharacterized protein FLJ45252	0	0	3	3
Acyl-CoA dehydrogenase family member 11	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	3	3
Serine/threonine-protein kinase MARK2	0	0	3	3
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	3	3
STE20-related kinase adapter protein alpha	0	0	3	3
Myosin-14	0	0	3	3
AarF domain-containing protein kinase 1	0	0	3	3
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	3	3
Cyclin-dependent kinase-like 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	3	3
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Misshapen-like kinase 1	0	0	3	3
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	3	3
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	3	3
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	2	2
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
Aurora kinase B	0	3	4	7
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	3	3
Cyclin-dependent kinase 15	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	3	3
EKC/KEOPS complex subunit TP53RK	0	0	3	3
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 5	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	3	3
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	3	3
Serine/threonine-protein kinase D2	0	0	3	3
Serine/threonine-protein kinase DCLK3	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	3	3
Serine/threonine-protein kinase SIK2	0	0	3	3
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO3	0	0	3	3
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	3	2	5
dCTP pyrophosphatase 1	0	0	3	3
Dual specificity protein kinase CLK4	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	1	2	3
Casein kinase I isoform gamma-1	0	0	3	3
Serine/threonine-protein kinase PAK 6	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	3	3
BMP-2-inducible protein kinase	0	0	3	3
Obg-like ATPase 1	0	0	3	3
Midasin	0	0	3	3
Interleukin-1 receptor-associated kinase 4	0	0	3	3
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	3	3
Cyclin-dependent kinase 12	0	0	3	3
Serine/threonine-protein kinase PLK2	0	3	2	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	3	3
eIF-2-alpha kinase GCN2	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	3	3
Serine/threonine-protein kinase NLK	0	0	3	3
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	3	3
Serine/threonine-protein kinase TBK1	0	1	3	4
Septin-9	0	0	3	3
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	3	3
TRAF2 and NCK-interacting protein kinase	0	0	3	3
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	3	3
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
ALK tyrosine kinase receptor	0	3	2	5
SRSF protein kinase 3	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	3	3
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase 38-like	0	0	2	2
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 2	0	0	3	3
Thyroid hormone receptor-associated protein 3	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 3	0	0	3	3
Serine/threonine-protein kinase MRCK beta	0	0	3	3
Interleukin-1 receptor-associated kinase 3	0	0	3	3
Serine/threonine-protein kinase 24	0	0	3	3
Casein kinase I isoform gamma-3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 4	0	0	3	3
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
Chain A, RNA-directed RNA polymerase NS5	0	2	0	2
Chain A, Cruzipain	14	0	0	14
BRCA1	2	0	0	2
WRN	3	0	0	3
Lysine-specific demethylase 4E	0	2	0	2
Replicase polyprotein 1ab	0	2	4	6
hemoglobin subunit beta	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	5	0	0	5
thyroid hormone receptor beta isoform a	17	0	0	17
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
DNA polymerase eta isoform 1	5	0	0	5
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Lysine-specific histone demethylase 1A	0	7	0	7
Rap guanine nucleotide exchange factor 3	4	0	0	4
Glucocorticoid receptor	0	13	2	18
Cytochrome P450 1A1	0	5	1	6
Progesterone receptor	0	6	3	9
Trypsin-1	0	3	0	3
Trypsin-2	0	3	0	3
Fructose-1,6-bisphosphatase 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	7	0	7
Replicase polyprotein 1ab	0	8	6	14
Replicase polyprotein 1ab	0	9	9	18
Lysosomal alpha-glucosidase	0	2	0	2
Androgen receptor	0	9	5	20
Cytochrome P450 2C9	0	18	1	19
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Sucrase-isomaltase, intestinal	0	2	0	2
G2/mitotic-specific cyclin-B1	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Urease subunit alpha	0	4	0	4
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Cyclic AMP-responsive element-binding protein 1	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Glutamate receptor 1	1	0	1	2
Glutamate receptor 3	1	0	1	2
Glutamate receptor 4	1	0	1	2
UDP-glucuronosyltransferase 1A1	0	5	0	7
Sucrase-isomaltase, intestinal	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Dipeptidyl peptidase 4	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
5-hydroxytryptamine receptor 7	0	4	0	4
Trypsin-3	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	5
Linoleate 9S-lipoxygenase-4	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prolyl endopeptidase	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Casein kinase II subunit beta	0	3	0	3
Urease subunit beta	0	4	0	4
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Lactoylglutathione lyase	0	4	0	4
Receptor-type tyrosine-protein phosphatase S	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Cytochrome P450 1B1	0	8	1	9
Prostaglandin G/H synthase 1	0	4	0	5
Integrase	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Casein kinase II subunit alpha 3	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
G-protein coupled receptor 35	0	2	2	4
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Sialidase-2	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
pyruvate kinase PKM isoform a	2	0	0	2
Telomerase reverse transcriptase	0	1	0	1
Acetylcholinesterase	0	7	0	7
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	3
Aldo-keto reductase family 1 member C3	0	3	0	3
Aldo-keto reductase family 1 member C2	0	2	0	2
Cholinesterase	0	7	0	7
Inositol monophosphatase 1	11	0	0	11
pregnane X receptor	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
galanin receptor type 3	0	2	0	2
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
Muscarinic acetylcholine receptor M2	0	9	3	16
Muscarinic acetylcholine receptor M4	0	8	2	12
Muscarinic acetylcholine receptor M5	0	8	2	12
Muscarinic acetylcholine receptor M1	0	9	2	14
Muscarinic acetylcholine receptor M3	0	9	2	13
Chain A, Beta-lactamase	16	0	0	16
activating transcription factor 6	17	0	0	17
Estrogen receptor	0	13	4	18
Progesterone receptor	0	2	0	2
Glucocorticoid receptor	0	2	0	2
Androgen receptor	0	2	2	4
Mineralocorticoid receptor	0	2	0	2
Progesterone receptor	0	2	0	2
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
GALC protein	5	0	0	5
GTPase KRas	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	5	0	5
Aldo-keto reductase family 1 member B1	0	16	0	16
Polyunsaturated fatty acid lipoxygenase ALOX15	0	8	0	8
Sodium-dependent noradrenaline transporter	0	16	2	18
Estrogen-related receptor gamma	0	2	0	2
GTP-binding protein Rheb	0	0	1	1
Estrogen receptor beta	0	7	4	11
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
DNA polymerase beta	9	0	0	9
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Adenosine receptor A3	0	15	0	15
Amine oxidase [flavin-containing] A	0	6	0	6
Amine oxidase [flavin-containing] B	0	9	0	9
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	9	2	12
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	6	1	9
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	4	1	6
Phosphodiesterase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	10	2	13
Guanine deaminase	0	2	0	2
L-lactate dehydrogenase A chain	0	2	0	2
Cytochrome P450 1A2	0	9	1	11
Cytochrome P450 2C11	0	1	0	1
Cytochrome P450 2A6	0	3	1	4
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Cannabinoid receptor 1	0	3	1	4
Cytochrome P450 2B6	0	5	1	6
Cytochrome P450 3A5	0	2	0	3
Cannabinoid receptor 1	0	4	1	7
Cytochrome P450 3A7	0	1	0	1
5-hydroxytryptamine receptor 2C	0	8	0	8
Caspase-1	0	2	1	3
Cytochrome P450 2C19	0	11	1	13
Cannabinoid receptor 2	0	4	2	8
Mu-type opioid receptor	0	12	2	16
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Delta-type opioid receptor	0	9	1	12
Kappa-type opioid receptor	0	11	1	14
N-acylethanolamine-hydrolyzing acid amidase	0	1	0	1
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	2	2	4
Transient receptor potential cation channel subfamily V member 1	0	3	2	6
Transient receptor potential cation channel subfamily M member 8	0	1	0	1
Transient receptor potential cation channel subfamily V member 4	0	1	2	3
Transient receptor potential cation channel subfamily V member 2	0	1	2	3
G-protein coupled receptor 55	0	1	2	3
Diacylglycerol lipase-alpha	0	1	0	1
Histamine H3 receptor	0	4	2	7
Liver carboxylesterase 1	0	0	0	1
67.9K protein	18	0	0	18
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	2	0	2
Corticotropin-releasing factor receptor 2	0	1	0	1
thyrotropin-releasing hormone receptor	7	0	0	7
Neuronal acetylcholine receptor subunit alpha-3	0	4	2	7
Muscarinic acetylcholine receptor M1	0	5	1	9
Muscarinic acetylcholine receptor M3	0	5	1	8
Muscarinic acetylcholine receptor M4	0	5	0	7
Muscarinic acetylcholine receptor M5	0	5	0	7
Muscarinic acetylcholine receptor M2	0	5	0	7
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	4	2	7
Muscarinic acetylcholine receptor M1	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Delta-type opioid receptor	0	3	0	5
Neuronal acetylcholine receptor subunit alpha-6	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	6
Sigma non-opioid intracellular receptor 1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Arginase	0	3	0	3
Pancreatic triacylglycerol lipase	0	2	0	2
Prothrombin	0	2	2	5
Carbonic anhydrase 4	0	11	0	16
Carbonic anhydrase 6	0	6	0	11
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Beta-secretase 1	0	5	0	5
Carbonic anhydrase 3	0	2	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
interferon gamma precursor	0	0	0	4
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Prostaglandin E synthase	0	2	0	2
Histone deacetylase 3	0	5	0	5
Carbonic anhydrase 12	0	5	0	10
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Carbonic anhydrase 3	0	4	0	8
Procathepsin L	0	1	4	5
Quinolone resistance protein NorA	0	2	0	2
Beta-3 adrenergic receptor	0	4	1	5
Calpain-2 catalytic subunit	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cruzipain	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	6	1	10
Bifunctional epoxide hydrolase 2	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	7	0	12
Carbonic anhydrase	0	5	0	8
Carbonic anhydrase 7	0	6	0	11
Carbonic anhydrase	0	1	0	5
Histone deacetylase 4	0	4	0	4
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	6	0	6
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Histone deacetylase 1	0	6	0	6
Carbonic anhydrase 9	0	8	0	13
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	5
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	2	0	4
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	4	0	4
Rap guanine nucleotide exchange factor 4	3	0	0	3
Histone deacetylase 2	0	6	0	6
Carbonic anhydrase 4	0	2	0	4
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	4	0	4
Carbonic anhydrase 15	0	4	0	7
Histone deacetylase 8	0	5	0	5
P2Y purinoceptor 12	0	1	0	1
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	3	0	3
Carbonic anhydrase 14	0	4	0	9
Histone deacetylase 5	0	4	0	4
Carbonic anhydrase 5B, mitochondrial	0	6	0	11
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Carbonic anhydrase 13	0	3	0	8
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	5	0	5
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	3	3
Vitamin D3 receptor	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	5	0	5
Thiosulfate sulfurtransferase	0	5	0	5
60 kDa chaperonin	0	6	0	6
10 kDa chaperonin	0	6	0	6
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	3	0	3
perilipin-1	0	3	0	3
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	3	0	3
Beta-lactamase	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Thrombopoietin	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
Solute carrier family 22 member 2	0	5	0	8
Solute carrier family 22 member 3	0	5	0	6
Solute carrier family 22 member 3	0	2	0	2
Mineralocorticoid receptor	0	2	1	3
C-8 sterol isomerase	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	4	0	5
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	1	4
Solute carrier family 22 member 1	0	5	0	6
Solute carrier family 22 member 2	0	5	0	6
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Nrf2	2	0	0	2
alkaline phosphatase, intestinal	0	1	1	2
apical membrane antigen 1, AMA1	6	0	0	6
PINK1	2	0	0	2
Parkin	8	0	0	8
toll-like receptor 9	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	8	0	0	8
TPA: protein transporter TIM10	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	1	2
intestinal alkaline phosphatase precursor	0	1	1	2
transcriptional regulator ERG isoform 3	8	0	0	8
huntingtin isoform 2	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	2	0	3
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
caspase-1 isoform alpha precursor	1	0	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Amyloid-beta precursor protein	0	6	1	8
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	2	0	2
Glutathione S-transferase P	0	1	0	1
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Heme oxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Proteasome subunit beta type-5	0	3	0	3
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Caspase-7	2	0	0	2
Guanine nucleotide-binding protein G	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	2	3
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Phosphodiesterase	0	2	0	2
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	5	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	5	0	5
Matrix metalloproteinase-9	0	3	0	3
Isocitrate lyase	0	1	0	1
Neuraminidase	0	3	0	3
pyruvate kinase	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Aldo-keto reductase family 1 member B10	0	1	0	1
Transthyretin	0	1	1	2
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Ornithine decarboxylase	1	0	0	2
Tyrosinase	0	3	0	3
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	1	0	4
Estrogen receptor	0	0	1	1
Transporter	0	1	0	1
Substance-K receptor	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Prenyltransferase homolog	0	0	0	2
Estrogen receptor beta	0	0	1	1
Vasopressin V2 receptor	0	2	1	3
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	3	1	4
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
G-protein coupled bile acid receptor 1	0	0	3	3
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Steryl-sulfatase	0	0	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	10	0	12
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
Solute carrier organic anion transporter family member 1B1	0	9	0	11
Thymidine kinase 2	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	0	0	2
AAA family ATPase	0	0	0	2
Reverse transcriptase/RNaseH	0	0	1	1
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
Plasma kallikrein	0	1	0	4
Sex hormone-binding globulin	0	1	0	1
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	2	1	3
Neuropeptide FF receptor 2	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 6	0	3	0	6
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	3	0	4
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Serum paraoxonase/arylesterase 1	0	3	0	3
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
D(1A) dopamine receptor	11	0	0	11
5-hydroxytryptamine receptor 4	0	6	0	6
Interstitial collagenase	0	3	1	4
Beta-2 adrenergic receptor	0	2	1	3
Angiotensin-converting enzyme	0	6	0	6
5-hydroxytryptamine receptor 2B	0	10	0	10
D(1A) dopamine receptor	7	0	0	7
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
Fatty-acid amide hydrolase 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Transient receptor potential cation channel subfamily A member 1	0	1	2	4
Cannabinoid receptor 1	0	2	0	2
N-arachidonyl glycine receptor	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoglyceride lipase	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Cannabinoid receptor 2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	3	0	3
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	6	0	10
Glutamate receptor ionotropic, NMDA 2A	0	6	0	10
Glutamate receptor ionotropic, NMDA 2B	0	6	0	10
Glutamate receptor ionotropic, NMDA 2C	0	6	0	10
Glutamate receptor ionotropic, NMDA 1	0	5	0	5
Glutamate receptor ionotropic, NMDA 2A	0	5	0	5
Glutamate receptor ionotropic, NMDA 2D	0	6	0	10
Glutamate receptor ionotropic, NMDA 3B	0	6	0	10
Glutamate receptor ionotropic, NMDA 3A	0	6	0	10
UDP-glucuronosyltransferase 2B7	0	1	0	3
Lanosterol 14-alpha demethylase	0	0	2	2
Olfactory receptor 51E2	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
Vpr	1	0	0	1
Cytochrome P450 2B1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	4	0	4
Sulfotransferase 1A1	0	2	1	4
Aldehyde oxidase	0	1	0	1
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	4	0	4
Multidrug and toxin extrusion protein 1	0	7	0	7
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	4	0	4
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	5	0	5
Caspase-3	0	2	0	2
DNA topoisomerase 2-alpha	0	0	0	1
Tubulin beta-2B chain	0	2	1	5
Similar to alpha-tubulin isoform 1	0	2	1	5
Similar to alpha-tubulin isoform 1	0	2	0	4
Cathepsin B	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
fructose-bisphosphate aldolase	0	1	0	1
Bile acid receptor	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	2	3
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	2	2
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	2	2
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
Cocaine esterase	0	1	0	2
Bile salt export pump	0	7	0	7
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
epidermal growth factor receptor isoform a precursor	1	1	0	2
Cytochrome P450 2E1	0	1	0	1
Cytochrome P450 2C8	0	2	0	3
Myosin light chain kinase, smooth muscle	0	0	1	1
Sodium-dependent dopamine transporter	0	4	0	4
Type-1 angiotensin II receptor	0	3	1	4
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Tubulin alpha-1A chain	0	0	1	1
Synaptic vesicular amine transporter	0	3	0	3
Transcription factor p65	0	2	0	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Spike glycoprotein	0	0	4	4
Transmembrane protease serine 2	0	0	4	4
Replicase polyprotein 1a	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
Equilibrative nucleoside transporter 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	4	4
Asialoglycoprotein receptor 1	0	1	1	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain E, Fibrin beta chain	0	1	0	1
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
luciferase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
Vif	0	2	0	2
Tat	0	1	0	1
endoribonuclease toxin MazF	0	0	1	1
Pyruvate kinase PKM	0	1	0	1
Endothelin receptor type B	2	0	0	2
Endothelin-1 receptor	2	0	0	2
phosphoglycerate kinase	3	0	0	3
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Solute carrier family 22 member 8	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	5	2	7
5-hydroxytryptamine receptor 1D	0	1	0	3
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	3	1	4
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H1 receptor	0	5	2	7
Histamine H3 receptor	0	2	0	2
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase-like protein, putative	0	0	0	3
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	2	2	4
Histamine H3 receptor	0	2	1	3
Carboxylic ester hydrolase	0	0	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	5	0	5
Acid-sensing ion channel 3	0	1	0	1
Albumin	0	1	2	7
Albumin	0	0	1	1
Fatty acid-binding protein, intestinal	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	3
Caspase-4	0	1	0	1
Cytochrome P450 2J2	0	3	0	3
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Snq2p	0	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Major prion protein	0	0	1	1
Sphingomyelin phosphodiesterase	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	4	0	4
D(2) dopamine receptor	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Envelope glycoprotein	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Transporter	0	3	1	5
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Heat shock protein HSP 90-alpha	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	0	1	1
Cyclin-A2	0	1	0	1
Nitric oxide synthase, brain	0	4	0	4
Cyclin-A1	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	5
Proton-coupled amino acid transporter 1	0	2	0	3
NPYLR7B	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
dopamine D1 receptor	3	0	0	3
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
Solute carrier family 15 member 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
streptokinase A precursor	0	0	3	3
Tubulin beta-4A chain	0	2	1	4
Tubulin beta chain	0	2	1	4
Tubulin alpha-3C chain	0	2	1	4
Tubulin alpha-1B chain	0	2	1	4
Tubulin alpha-4A chain	0	2	1	4
Tubulin beta-4B chain	0	2	1	4
DNA gyrase subunit A	0	2	0	2
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	3	1	5
Tubulin beta-2A chain	0	2	1	4
Tubulin beta-8 chain	0	2	1	4
Tubulin alpha-3E chain	0	2	1	4
Tubulin alpha-1A chain	0	2	1	4
Tubulin alpha-1C chain	0	2	1	4
Tubulin beta-6 chain	0	2	1	4
Tubulin beta-2B chain	0	2	1	4
Tubulin beta-1 chain	0	2	1	4
Potassium channel subfamily K member 3	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Protease	0	3	2	7
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	2	0	2
Protease	0	4	3	7
Neprilysin	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Thromboxane A2 receptor	0	1	0	2
Squalene synthase	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	1	1	2
Alpha-mannosidase 2C1	0	1	1	2
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	2	0	2
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	1	1	2
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	2
Mu-type opioid receptor	0	1	0	1
voltage-dependent T-type calcium channel subunit alpha-1H isoform a	0	0	1	1
Beta-1 adrenergic receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Neutrophil elastase	0	4	0	4
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Nitric oxide synthase, inducible	0	4	0	4
Nitric oxide synthase, inducible	0	2	0	2
Collagenase 3	0	3	0	3
beta-2 adrenergic receptor	2	0	0	2
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
tumor necrosis factor	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
Glutathione reductase, mitochondrial	0	3	0	3
Phospholipase A2, membrane associated	0	0	0	1
Thromboxane-A synthase	0	3	0	3
Platelet-activating factor receptor	0	0	0	1
C-C chemokine receptor type 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
Leukotriene B4 receptor 1	0	0	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium/iodide cotransporter	0	1	0	1
Estrogen receptor	0	0	2	3
Estrogen receptor beta	0	0	2	3
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Genome polyprotein	0	1	0	1
Tubulin alpha-1A chain	0	0	1	2
Tubulin beta chain	0	0	1	1
Integrin alpha-V	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Substance-K receptor	0	6	0	6
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Bcl-2-like protein 1	0	2	0	2
Beta-tubulin	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	3
Alpha-1B adrenergic receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1B adrenergic receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	2	0	3
Alpha-2C adrenergic receptor	0	2	0	3
Alpha-2A adrenergic receptor	0	2	0	3
Phenylethanolamine N-methyltransferase	0	0	0	1
Complement C1s subcomponent	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Histamine H3 receptor	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
Beta-casein	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	1	0	2
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	2	0	0	2
hexokinase	0	1	0	1
galactokinase	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	2	2
G2/mitotic-specific cyclin-B	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
ClpP	1	0	0	1
P53	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
POsterior Segregation	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Myc proto-oncogene protein	0	1	0	2
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Ornithine decarboxylase	0	1	0	1
Estrogen receptor	0	0	1	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Lysosomal alpha-glucosidase	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Zinc finger protein mex-5	0	0	1	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Programmed cell death protein 4	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Carbonic anhydrase	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	1	2
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	1	1
Chain A, CES1 protein	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Cereblon isoform 4	0	2	0	2
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Lower Urinary Tract Symptom

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (797)

Protein Targets (2,025)

Lower Urinary Tract Symptom

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (797)

Drugs Studied (283)

Protein Targets (2,025)