Manganese Poisoning

Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)

Synonym
Neurotoxicity Syndrome, Manganese
Manganese Poisoning
Nervous System Poisoning, Manganese
Poisoning, Manganese
Nervous System Diseases, Manganese-Induced

Excerpt	Reference
"Chronic manganese poisoning is characterized by mental and extrapyramidal disturbances."	( Nakashima, S, 1983)
"Manganese poisoning is a disease which results from chronic exposure to manganese, but the source of manganese exposure remained obscure in this patient."	( Iwabuchi, K; Katsuragi, T; Nagatomo, H; Shibuya, K; Takahashi, T, 1996)
"Manganese poisoning is associated with irreversible neurologic toxicity."	( Hines, EQ; Hoffman, RS; Howland, MA; Smith, SW; Soomro, I, 2016)

Excerpt	Reference
"Two cases of chronic manganese poisoning were treated with sodium para-aminosalicylic acid (PAS-Na; 6 g/day in 500 ml of 10% glucose solution by intravenous drip)."	( Deng, HS; Hu, W; Ky, SQ; Xie, PY, 1992)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	371 (41.59)	23.3326
1990's	148 (16.59)	12.5806
2000's	157 (17.60)	18.1394
2010's	174 (19.51)	28.8240
2020's	42 (4.71)	9.53

Drug	Relationship Strength	Studies	Trials
2,3-dihydroxybenzoic acid	low	1	0
3-hydroxyanthranilic acid	low	1	0
3-hydroxykynurenine	low	1	0
gamma-aminobutyric acid	low	20	0
aminolevulinic acid	low	2	0
5-hydroxytryptophan	medium	2	2
ethylene glycol	low	1	0
acetic acid	low	1	0
acetaldehyde	low	2	0
ammonium hydroxide	low	3	0
benzene	low	1	0
bromide	low	1	0
carbon monoxide	low	1	0
chlordecone	low	1	0
choline	low	5	0
chlorine	low	95	0
salicylic acid	low	2	0
hydrogen sulfide	low	2	0
3,4-dihydroxyphenylacetic acid	low	3	0
creatine	low	1	0
lactic acid	low	2	0
dimethyl sulfoxide	low	2	0
formaldehyde	low	3	0
glycine	low	4	0
histamine	low	2	0
indoleacetic acid	low	1	0
iodine	low	3	0
dihydroxyphenylalanine	medium	32	3
kynurenine	low	1	0
thioctic acid	low	1	0
methanol	low	1	0
melatonin	low	1	0
nickel	low	37	0
niacin	low	1	0
nitrites	low	1	0
1-propanol	low	1	0
pyridoxal phosphate	medium	7	1
pyridoxine	low	2	0
taurine	low	1	0
thiamine	low	1	0
thymine	low	1	0
toluene	low	1	0
uric acid	low	2	0
urea	low	1	0
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	low	1	0
vanilmandelic acid	low	2	0
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	low	2	0
monomethylpropion	low	20	0
3-methylcholanthrene	low	1	0
3-nitropropionic acid	low	2	0
homovanillic acid	low	6	0
5,5-dimethyl-1-pyrroline-1-oxide	low	1	0
phenytoin	low	1	0
hydroxyindoleacetic acid	low	4	0
acetaminophen	low	1	0
amantadine	low	1	0
antipyrine	low	1	0
aspirin	low	3	0
benserazide	low	1	0
chlorpromazine	low	1	0
dantrolene	low	1	0
deferoxamine	low	2	0
amphetamine	low	2	0
pentetic acid	low	3	0
dimercaprol	low	3	0
racemetirosine	low	1	0
endosulfan	low	1	0
erythrosine	low	1	0
flutamide	low	1	0
2,5-dihydroxybenzoic acid	low	1	0
glyphosate	low	1	0
gossypol	low	1	0
hexachlorophene	low	1	0
hexobarbital	low	1	0
ibuprofen	low	1	0
indomethacin	low	1	0
isoniazid	low	1	0
isoproterenol	low	1	0
edaravone	low	1	0
memantine	low	1	0
mesalamine	low	1	0
muscimol	low	2	0
nimodipine	low	1	0
nomifensine	low	1	0
oxidopamine	low	1	0
aminosalicylic acid	low	12	0
pargyline	low	1	0
pentoxifylline	low	1	0
perhexiline	low	1	0
phenobarbital	low	3	0
pifithrin	low	1	0
pinacidil	low	1	0
riluzole	low	3	0
sodium fluoride	low	1	0
spiperone	low	3	0
sulfobromophthalein	low	2	0
tremorine	low	1	0
trientine	low	1	0
urethane	low	1	0
zinc chloride	low	1	0
reserpine	low	2	0
thymidine	low	5	0
hydroxyproline	low	2	0
penicillamine	low	2	0
dehydroepiandrosterone	low	1	0
adrenochrome	low	1	0
pentylenetetrazole	low	1	0
carbon tetrachloride	low	1	0
aspartic acid	low	3	0
glutamine	low	6	0
cyanides	medium	1	1
sucrose	low	1	0
ethinyl estradiol	low	1	0
apomorphine	medium	5	1
tetrabenazine	low	1	0
bromodeoxyuridine	low	1	0
levodopa	medium	26	2
edetic acid	medium	31	1
tyrosine	low	6	0
aniline	low	1	0
methionine	low	2	0
phenylalanine	medium	2	1
cycloheximide	low	1	0
mannitol	low	2	0
tryptophan	low	3	0
n,n'-diphenyl-4-phenylenediamine	low	1	0
arginine	low	1	0
methyl iodide	low	3	0
boranes	low	1	0
vinyl chloride	low	1	0
methylene chloride	low	1	0
carbon disulfide	low	7	0
2-bromopropane	low	1	0
vinylidene chloride	low	1	0
propylene oxide	low	1	0
phencyclidine	low	24	0
tromethamine	low	1	0
tetraethyl lead	low	2	0
skatole	low	1	0
rotenone	low	2	0
2,4-xylidine	low	1	0
ethylbenzene	low	1	0
styrene	low	1	0
quinuclidines	low	1	0
pyridostigmine bromide	low	1	0
2-methylpentane	low	2	0
1,3-butylene glycol	low	1	0
vinyl acetate	low	1	0
methyl isobutyl ketone	low	4	0
thiophenes	low	1	0
n-hexane	low	1	0
nitrilotriacetic acid	low	1	0
3-o-methylglucose	low	1	0
thiamine pyrophosphate	low	1	0
acridines	low	1	0
cyclopentane	low	3	0
thiazoles	low	3	0
nitroblue tetrazolium	low	1	0
ephedrine	low	4	0
hydrazine	low	1	0
azacitidine	low	1	0
fusarium	low	1	0
cdta	low	1	0
malondialdehyde	low	7	0
1-naphthylisothiocyanate	low	2	0
methyl n-butyl ketone	low	4	0
manganese carbonate	low	1	0
acetylcysteine	low	5	0
nicotinamide mononucleotide	low	1	0
manganese dioxide	low	19	0
zinc oxide	low	1	0
vanadium pentoxide	low	1	0
d-alpha tocopherol	low	2	0
s,n,n'-tripropylthiocarbamate	low	1	0
methionine sulfoximine	low	1	0
benperidol	low	1	0
fucose	low	1	0
carbonates	low	1	0
buthionine sulfoximine	low	2	0
n-methylaspartate	low	2	0
manganese	medium	521	5
mercury	low	20	0
molybdenum	low	14	0
palladium	low	3	0
platinum	low	3	0
rhodium	low	1	0
silver	low	1	0
titanium	low	4	0
tungsten	low	2	0
cadmium	low	31	0
chromium	low	31	0
gadolinium	low	1	0
gold	low	2	0
uranium	low	2	0
vanadium	low	11	0
cupric chloride	low	2	0
ferric chloride	low	1	0
nickel chloride	low	4	0
zinc sulfate	low	1	0
ferrous chloride	low	1	0
chromates	low	1	0
deuterium	low	1	0
fluorine	low	2	0
nickel sulfate	low	2	0
molybdate ion	low	2	0
ozone	low	1	0
cadmium chloride	low	4	0
titanium dioxide	low	2	0
thiamphenicol	low	1	0
tetradecanoylphorbol acetate	low	2	0
fluorides	low	1	0
lisuride	low	1	0
phenyl acetate	low	5	0
cetylpyridinium chloride anhydrous	low	1	0
4-methoxyamphetamine	low	1	0
transferrin	low	1	0
glutamic acid	low	15	0
substance p	low	1	0
methyldopa	low	2	0
1-methyl-4-phenylpyridinium	low	1	0
ng-nitroarginine methyl ester	low	1	0
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	low	3	0
fomesafen	medium	1	1
lovastatin	low	2	0
fluorodopa f 18	low	6	0
cymantrene	low	2	0
vanadates	low	1	0
thiazolyl blue	low	3	0
n-acetylaspartic acid	low	2	0
bathocuproine	low	1	0
1,7-phenanthroline	low	1	0
fluorodeoxyglucose f18	low	2	0
prochloraz	low	1	0
tes	low	1	0
hydroxyflutamide	low	1	0
phorbolol myristate acetate	low	1	0
cobalt	low	19	0
carbidopa, levodopa drug combination	low	2	0
deoxyglucose	low	1	0
ponasterone a	low	1	0
buthionine sulfoximine ethyl ester	low	1	0
molybdenum chloride	low	1	0
hydroxyl radical	low	1	0
n(3)-ethylthymidine	low	1	0
anacardic acid	low	1	0
organophosphonates	low	1	0
3-nitrotyrosine	low	1	0
pifithrin mu	low	1	0
lithium chloride	low	1	0
n-acetylneuraminic acid	low	1	0
tosylphenylalanyl chloromethyl ketone	low	1	0
taurolithocholic acid	low	2	0
dehydroascorbic acid	low	1	0
strychnine	low	2	0
n-formylmethionine leucyl-phenylalanine	low	1	0
acetyl coenzyme a	low	1	0
trichostatin a	low	1	0
cocaine	low	1	0
diethylstilbestrol	low	1	0
enkephalin, leucine	low	1	0
potassium permanganate	low	10	0
isomethyleugenol	low	3	0
curcumin	low	1	0
succimer	low	1	0
tamoxifen	low	2	0
nadp	low	1	0
nabam	low	2	0
pica	low	1	0
lithium	low	1	0
zineb	low	2	0
cobaltous chloride	low	3	0
nitrogen dioxide	low	1	0
maneb	low	2	0
raclopride	low	3	0
17-ketosteroids	low	1	0
myelin basic protein	low	1	0
bilirubin	low	11	0
dinoprostone	low	2	0
alpha-linolenic acid	low	1	0
humulene	low	1	0
lead	low	48	0
tin	low	6	0
antimony	low	1	0
barium	low	3	0
rubidium	low	1	0
aluminum	low	16	0
ethylmorphine	low	1	0
strontium	low	2	0
bismuth	low	3	0
thallium	low	7	0
arsenic	low	9	0
dextromethorphan	low	1	0
sulfur	low	1	0
ecdysterone	low	1	0
beryllium	low	3	0
cysteine	low	1	0
silicon	low	1	0
phosphorus	low	2	0
boron	low	1	0
tyrphostin ag825	low	1	0
selenium	low	9	0
tellurium	low	3	0
dizocilpine maleate	low	2	0
nitrofurantoin	low	1	0
mocetinostat	low	1	0
alpha-synuclein	low	5	0
ribose	low	1	0
technetium tc 99m exametazime	low	1	0
acid phosphatase	low	7	0
nad	low	2	0
glucagon	low	2	0
barium ferrite	low	1	0
chlorophyll a	low	1	0
florbenazine f 18	low	1	0
calpain	low	1	0
stearates	low	1	0
neurotensin	low	1	0
peptones	low	1	0
heme	low	1	0
ascorbic acid	low	6	0
salicylates	low	1	0
n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid	medium	7	1
pyrethrins	low	1	0
glutaminase	low	2	0
transforming growth factor alpha	low	1	0
cyclosporine	low	1	0
amyloid beta-peptides	low	1	0
sapropterin	low	1	0
manganese-zinc ferrite	low	3	0
carbidopa	low	4	0
metallothionein	low	4	0
phosphorus radioisotopes	low	1	0

Protein Targets (1,860)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Dihydropteridine reductase	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	5
Amine oxidase [flavin-containing] B	0	5	1	6
Amine oxidase [flavin-containing] B	0	1	0	2
Solute carrier family 22 member 1	0	1	0	3
Solute carrier family 22 member 2	0	3	0	10
Solute carrier family 22 member 1	0	7	0	14
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 3	0	2	0	4
Solute carrier family 22 member 3	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Sodium-dependent serotonin transporter	0	23	3	26
Solute carrier family 22 member 1	0	6	0	9
Solute carrier family 22 member 2	0	5	0	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	37	0	0	37
Chain A, HADH2 protein	26	0	0	26
Chain B, HADH2 protein	26	0	0	26
15-lipoxygenase, partial	25	0	0	25
hypoxia-inducible factor 1 alpha subunit	23	0	0	23
RAR-related orphan receptor gamma	61	0	0	61
GLI family zinc finger 3	56	0	0	56
AR protein	75	0	0	75
aldehyde dehydrogenase 1 family, member A1	51	0	0	51
estrogen receptor 2 (ER beta)	34	0	0	34
nuclear receptor subfamily 1, group I, member 3	46	0	0	46
progesterone receptor	36	0	0	36
glucocorticoid receptor [Homo sapiens]	62	0	0	62
retinoic acid nuclear receptor alpha variant 1	70	0	0	70
retinoid X nuclear receptor alpha	50	0	0	50
estrogen-related nuclear receptor alpha	74	0	0	74
farnesoid X nuclear receptor	35	0	0	35
pregnane X nuclear receptor	47	0	0	47
estrogen nuclear receptor alpha	90	0	0	90
peroxisome proliferator-activated receptor delta	44	0	0	44
peroxisome proliferator activated receptor gamma	42	0	0	42
vitamin D (1,25- dihydroxyvitamin D3) receptor	40	0	0	40
aryl hydrocarbon receptor	31	0	0	31
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	39	0	0	39
thyroid stimulating hormone receptor	29	0	0	29
activating transcription factor 6	33	0	0	33
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	25	0	0	25
v-jun sarcoma virus 17 oncogene homolog (avian)	32	0	0	32
Histone H2A.x	25	0	0	25
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	20	0	0	20
heat shock protein beta-1	26	0	0	26
nuclear factor erythroid 2-related factor 2 isoform 1	61	0	0	61
nuclear receptor ROR-gamma isoform 1	32	0	0	32
cytochrome P450 3A4 isoform 1	37	0	0	37
Gamma-aminobutyric acid receptor subunit pi	37	8	1	46
ATP-binding cassette sub-family C member 3	0	24	0	24
Multidrug resistance-associated protein 4	0	25	0	26
Voltage-dependent calcium channel gamma-2 subunit	38	0	0	38
Bile salt export pump	0	46	0	46
Glucocorticoid receptor	0	6	0	6
Cellular tumor antigen p53	47	0	0	47
Cytochrome P450 1A2	0	7	1	9
Glycine receptor subunit alpha-1	0	7	0	7
Alpha-2A adrenergic receptor	0	16	0	16
Adenosine receptor A3	0	14	0	14
Androgen receptor	0	15	0	15
Gamma-aminobutyric acid receptor subunit beta-1	37	8	1	46
Alpha-1B adrenergic receptor	0	23	0	23
Gamma-aminobutyric acid receptor subunit delta	37	8	1	46
Gamma-aminobutyric acid receptor subunit gamma-2	37	8	2	47
Alpha-2C adrenergic receptor	0	14	0	14
Glutamate receptor 2	41	5	2	48
Gamma-aminobutyric acid receptor subunit alpha-5	37	8	1	46
Gamma-aminobutyric acid receptor subunit alpha-3	37	8	1	46
Glycine receptor subunit beta	0	6	0	6
D(1A) dopamine receptor	0	16	2	22
Glycine receptor subunit alpha-2	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	37	8	1	46
Gamma-aminobutyric acid receptor subunit alpha-2	37	8	1	46
Glycine receptor subunit alpha-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	37	8	1	46
Gamma-aminobutyric acid receptor subunit gamma-3	37	8	1	46
Gamma-aminobutyric acid receptor subunit alpha-6	37	8	1	46
5-hydroxytryptamine receptor 2B	0	18	0	18
C-C chemokine receptor type 2	0	2	0	2
Alpha-1A adrenergic receptor	0	25	0	25
Gamma-aminobutyric acid receptor subunit alpha-1	37	9	2	48
Gamma-aminobutyric acid receptor subunit beta-3	37	8	1	46
Gamma-aminobutyric acid receptor subunit beta-2	37	8	2	47
GABA theta subunit	37	8	1	46
Canalicular multispecific organic anion transporter 1	0	24	0	24
Gamma-aminobutyric acid receptor subunit epsilon	37	8	1	46
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	49	0	0	49
geminin	65	0	0	65
lamin isoform A-delta10	54	0	0	54
Guanine nucleotide-binding protein G	7	0	0	7
thyroid hormone receptor beta isoform a	30	0	0	30
Chain A, Neutrophil gelatinase-associated lipocalin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	18	0	0	18
72 kDa type IV collagenase	0	2	0	2
Matrilysin	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	4	0	4
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	2	0	2
Alpha-(1,3)-fucosyltransferase 7	0	2	0	2
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	2	0	2
chromobox protein homolog 1	44	0	0	44
ORF73	0	0	2	2
thioredoxin reductase	47	0	0	47
DNA polymerase iota isoform a (long)	34	0	0	34
Carbonic anhydrase 12	0	4	0	9
Carbonic anhydrase 1	0	19	0	27
Carbonic anhydrase 2	0	21	1	31
Polyunsaturated fatty acid 5-lipoxygenase	0	6	0	6
Aminopeptidase N	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	3	1	6
Carbonic anhydrase 7	0	5	0	10
Carbonic anhydrase 9	0	6	1	12
Carbonic anhydrase 14	0	4	0	9
Chain A, Phenazine biosynthesis protein phzF	0	0	1	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
GLS protein	40	0	0	40
TDP1 protein	55	0	0	55
isocitrate dehydrogenase 1, partial	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	17	0	0	17
DNA polymerase kappa isoform 1	26	0	0	26
replicative DNA helicase	0	0	0	4
recombinase A	0	0	4	4
Caspase-7	8	0	0	9
Caspase-9	0	1	0	2
large T antigen	0	5	0	5
Kynureninase	0	0	0	1
Luciferase	30	0	0	30
pregnane X receptor	20	0	0	20
phosphopantetheinyl transferase	34	0	0	34
SMAD family member 2	25	0	0	25
SMAD family member 3	25	0	0	25
Microtubule-associated protein tau	42	0	0	42
caspase 7, apoptosis-related cysteine protease	18	0	0	18
caspase-3	18	0	0	18
euchromatic histone-lysine N-methyltransferase 2	77	0	0	77
Tyrosine-protein kinase Lck	0	4	2	6
Tyrosine-protein kinase Fyn	0	8	2	10
Aldo-keto reductase family 1 member B1	0	22	0	22
Acetylcholinesterase	0	16	0	16
Sodium-dependent noradrenaline transporter	0	26	3	29
Aryl hydrocarbon receptor	0	0	1	1
acetylcholinesterase	26	0	0	26
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	16	0	0	16
thyrotropin-releasing hormone receptor	13	0	0	13
Bloom syndrome protein isoform 1	32	0	0	32
hemoglobin subunit beta	4	0	0	4
muscarinic acetylcholine receptor M1	23	0	0	23
Delta-aminolevulinic acid dehydratase	0	1	0	1
Isocitrate lyase 1	0	1	0	1
Isocitrate lyase	0	2	0	2
TAR DNA-binding protein 43	15	0	0	15
Isocitrate lyase	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	20	0	0	20
bromodomain adjacent to zinc finger domain 2B	20	0	0	20
pyruvate kinase PKM isoform a	2	0	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Tubulin--tyrosine ligase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	31	0	0	31
Chain A, Protocatechuate 3,4-dioxygenase	0	0	1	1
Chain M, Protocatechuate 3,4-dioxygenase	0	0	1	1
Olfactory receptor class A-like protein 1	0	0	1	1
endonuclease IV	13	0	0	13
RGS12	1	0	0	1
NFKB1 protein, partial	14	0	0	14
Thrombopoietin	8	0	0	8
alkaline phosphatase, intestinal	0	1	1	2
thioredoxin glutathione reductase	15	0	0	15
apical membrane antigen 1, AMA1	10	0	0	10
thyroid stimulating hormone receptor	49	0	0	49
hypothetical protein, conserved	5	0	0	5
regulator of G-protein signaling 4	32	0	0	32
lysosomal alpha-glucosidase preproprotein	9	0	0	9
peripheral myelin protein 22 isoform 1	20	0	0	20
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	2	0	2
intestinal alkaline phosphatase precursor	0	2	0	2
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
DNA polymerase beta	9	0	0	9
flap endonuclease 1	22	0	0	22
M-phase phosphoprotein 8	20	0	0	20
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
POsterior Segregation	0	0	3	3
Zinc finger protein mex-5	0	0	2	2
ATP-dependent phosphofructokinase	36	0	0	36
5-hydroxytryptamine receptor 2C	0	11	2	13
5-hydroxytryptamine receptor 2A	0	11	3	15
5-hydroxytryptamine receptor 1A	0	18	4	24
5-hydroxytryptamine receptor 1B	0	14	2	17
5-hydroxytryptamine receptor 1D	0	7	2	10
5-hydroxytryptamine receptor 1F	0	7	2	10
5-hydroxytryptamine receptor 2B	0	11	2	13
5-hydroxytryptamine receptor 6	0	2	2	4
Sodium-dependent serotonin transporter	0	9	0	10
5-hydroxytryptamine receptor 7	0	7	3	10
5-hydroxytryptamine receptor 5A	0	2	2	4
5-hydroxytryptamine receptor 5B	0	2	2	4
5-hydroxytryptamine receptor 3A	0	3	2	5
5-hydroxytryptamine receptor 4	0	3	2	5
5-hydroxytryptamine receptor 3B	0	3	2	5
Chain A, Beta-lactamase	21	0	0	21
Polyphenol oxidase 2	0	5	0	8
Prostaglandin G/H synthase 1	0	11	0	11
Sodium-dependent dopamine transporter	0	16	0	16
Prostaglandin G/H synthase 2	0	12	1	14
Xanthine dehydrogenase/oxidase	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	2	0	2
mu-type opioid receptor isoform MOR-1	0	0	2	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	11	0	0	11
5-hydroxytryptamine receptor 2A	0	0	2	2
Cytochrome P450 3A4	0	9	1	12
5-hydroxytryptamine receptor 1A	0	8	3	12
Neuronal acetylcholine receptor subunit alpha-4	3	4	0	7
Cytochrome P450 2C9	0	14	1	15
Neuronal acetylcholine receptor subunit beta-2	3	4	0	7
D(2) dopamine receptor	0	20	5	30
Translocator protein	0	2	1	4
D	0	12	0	12
D(3) dopamine receptor	0	10	0	11
Alpha-2B adrenergic receptor	0	11	0	12
D(2) dopamine receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	11	0	12
Alpha-2A adrenergic receptor	0	11	0	12
Alpha-1D adrenergic receptor	0	12	0	13
Alpha-1D adrenergic receptor	0	11	1	13
5-hydroxytryptamine receptor 1D	0	1	0	3
5-hydroxytryptamine receptor 1B	0	1	1	2
5-hydroxytryptamine receptor 2C	0	16	1	17
5-hydroxytryptamine receptor 7	0	4	0	4
Alpha-1A adrenergic receptor	0	2	1	4
Alpha-1B adrenergic receptor	0	3	1	5
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 6	0	15	0	15
5-hydroxytryptamine receptor 7	0	6	0	6
D(2) dopamine receptor	0	15	4	21
D	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	17	1	18
Lysosomal alpha-glucosidase	0	1	0	1
Transporter	0	6	0	6
Caspase-7	8	0	0	8
caspase-3	8	0	0	8
thyroid hormone receptor beta isoform 2	51	0	0	51
ATPase family AAA domain-containing protein 5	21	0	0	21
Ataxin-2	29	0	0	29
ATAD5 protein, partial	33	0	0	33
Smad3	18	0	0	18
EWS/FLI fusion protein	26	0	0	27
peripheral myelin protein 22	37	0	0	37
Solute carrier family 22 member 6	0	6	0	6
UDP-glucuronosyltransferase 1A9	0	1	0	5
Bile salt export pump	0	14	0	14
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	1	1	3
Prostaglandin G/H synthase 1	0	8	0	9
Carbonic anhydrase 3	0	3	0	8
Cytochrome P450 2D6	0	11	1	13
Polyunsaturated fatty acid lipoxygenase ALOX15	0	8	0	8
Sulfotransferase 1A1	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	2
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	5
Carbonic anhydrase 4	0	10	0	15
Carbonic anhydrase 6	0	5	0	10
Carbonic anhydrase 5A, mitochondrial	0	4	0	9
Nuclear receptor ROR-gamma	23	0	0	23
Cytochrome P450 2J2	0	8	0	8
Carbonic anhydrase 15	0	9	0	14
Carbonic anhydrase 13	0	4	0	8
Carbonic anhydrase 5B, mitochondrial	0	4	0	9
toxin B	0	0	0	1
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Fibrinogen C domain-containing protein 1	0	1	0	1
N-alpha-acetyltransferase 50	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	16	0	0	16
dopamine D1 receptor	4	0	0	4
USP1 protein, partial	35	0	0	35
arylsulfatase A	30	0	0	30
D(1A) dopamine receptor	11	0	0	11
survival motor neuron protein isoform d	19	0	0	19
Histone deacetylase 3	0	7	0	9
Histone deacetylase 4	0	6	1	10
Histone deacetylase 1	0	9	2	13
Histone deacetylase 7	0	6	0	8
Histone deacetylase 2	0	9	1	12
Polyamine deacetylase HDAC10	0	5	0	7
Histone deacetylase 11	0	6	0	8
Histone deacetylase 8	0	7	0	9
Histone deacetylase 6	0	7	1	10
Histone deacetylase 9	0	5	0	7
Histone deacetylase 5	0	6	0	8
Chain A, Ferritin light chain	14	0	0	14
alpha-galactosidase	6	0	0	6
DNA topoisomerase 2-alpha	0	0	0	1
vitamin D3 receptor isoform VDRA	31	0	0	31
histone acetyltransferase KAT2A isoform 1	21	0	0	21
Acetylcholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	7	0	7
Glutamate receptor ionotropic, NMDA 3B	0	7	0	7
Integrin beta-3	15	3	1	19
Integrin alpha-IIb	15	3	1	19
Glutamate receptor 1	3	5	2	10
Glutamate receptor 3	3	5	2	10
Glutamate receptor 4	3	5	2	10
Glutamate receptor ionotropic, kainate 1	0	5	1	6
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	19	4	29
Glutamate receptor ionotropic, kainate 1	0	3	1	4
Glutamate receptor ionotropic, kainate 2	0	5	1	6
Glutamate receptor 1	0	5	2	7
Glutamate receptor 2	0	5	2	7
Glutamate receptor 3	0	4	1	5
Glutamate receptor ionotropic, kainate 3	0	5	0	5
Excitatory amino acid transporter 1	0	4	0	5
Excitatory amino acid transporter 2	0	4	0	5
Excitatory amino acid transporter 3	0	4	0	5
Glutamate receptor 4	0	5	1	6
Glutamate receptor ionotropic, NMDA 2A	0	19	4	29
Glutamate receptor ionotropic, NMDA 2B	0	19	4	29
Glutamate receptor ionotropic, NMDA 2C	0	19	4	30
Glutamate receptor ionotropic, kainate 4	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	9	0	9
Glutamate receptor ionotropic, NMDA 2A	0	9	0	9
Glutamate receptor ionotropic, kainate 2	0	3	1	4
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	9	0	9
Glutamate receptor ionotropic, NMDA 2C	0	7	0	7
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	19	4	29
Glutamate receptor ionotropic, kainate 5	0	4	0	4
Glutamate receptor ionotropic, NMDA 3A	0	7	0	7
Glutamate receptor ionotropic, NMDA 3B	0	19	4	29
Glutamate receptor ionotropic, NMDA 3A	0	19	4	29
Glutamate receptor 4	0	1	0	1
Glutamate receptor 3	0	1	0	1
Chain A, Cruzipain	16	0	0	16
WRN	3	0	0	3
phospholipase A2 precursor	0	1	0	1
importin subunit beta-1 isoform 1	11	0	0	11
serine/threonine-protein kinase PLK1	5	0	0	5
snurportin-1	11	0	0	11
DNA polymerase eta isoform 1	6	0	0	6
cysteine protease ATG4B isoform a	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	7	0	0	7
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
DNA dC->dU-editing enzyme APOBEC-3F isoform a	3	0	0	3
Free fatty acid receptor 1	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	16	0	0	16
Prostaglandin G/H synthase 1	0	4	0	5
Nuclear receptor subfamily 1 group I member 2	0	1	3	4
Trypsin	0	2	0	2
Coagulation factor VII	0	2	0	2
Aromatase	0	2	0	2
Tissue factor	0	3	0	3
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Histamine H2 receptor	25	1	2	30
Prostaglandin G/H synthase 2	0	6	0	6
Free fatty acid receptor 4	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
putative alpha-glucosidase	1	0	0	1
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Spike glycoprotein	24	1	3	28
Multidrug and toxin extrusion protein 1	0	5	0	5
Gamma-aminobutyric acid receptor subunit rho-1	0	1	4	6
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	2	0	2
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	2	0	2
Substance-P receptor	0	3	0	3
Cytochrome P450 2A5	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Beta-2 adrenergic receptor	0	1	2	3
Sigma non-opioid intracellular receptor 1	0	7	1	8
Plasma kallikrein	0	1	0	7
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Replicase polyprotein 1ab	0	8	6	14
Peroxisome proliferator-activated receptor delta	0	0	0	1
Peroxisome proliferator-activated receptor alpha	2	0	1	3
Histone acetyltransferase p300	0	2	0	3
Probable linoleate 9S-lipoxygenase 5	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Histone acetyltransferase KAT8	0	2	0	4
SUMO-activating enzyme subunit 1	0	1	0	1
Steroid C26-monooxygenase	0	0	1	1
Cytochrome P450 130	0	0	1	1
Cytochrome P450 130	0	0	1	1
67.9K protein	22	0	0	22
Nicotinate phosphoribosyltransferase	0	4	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	34	0	0	34
cytochrome P450 2D6	25	0	0	25
cytochrome P450 2D6 isoform 1	14	0	0	14
cellular tumor antigen p53 isoform a	19	0	0	19
cytochrome P450 2C19 precursor	16	0	0	16
cytochrome P450 2C9 precursor	13	0	0	13
potassium voltage-gated channel subfamily H member 2 isoform d	29	0	0	29
mitogen-activated protein kinase 1	16	0	0	16
lethal factor (plasmid)	32	0	0	32
Tryptophan 5-hydroxylase 1	0	2	0	2
D(4) dopamine receptor	0	13	3	20
D(1B) dopamine receptor	0	5	0	8
D(1B) dopamine receptor	0	8	0	8
5-hydroxytryptamine receptor 2A	0	16	1	17
D(4) dopamine receptor	0	8	1	9
D(3) dopamine receptor	0	17	2	23
E3 ubiquitin-protein ligase Mdm2	0	2	0	2
D	0	4	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, brain	0	1	1	3
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	1	1	4
Cationic amino acid transporter 3	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
IDH1	23	0	0	23
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Alpha-2B adrenergic receptor	0	12	1	13
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	8
Carbonic anhydrase 4	0	0	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	15	0	0	15
glucocerebrosidase	11	0	0	11
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	11	1	12
Fatty acid-binding protein, liver	0	4	0	4
Myeloperoxidase	0	4	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	1	4	0	9
Adenosine receptor A2a	0	4	0	8
Substance-P receptor	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
glp-1 receptor, partial	17	0	0	17
Fumarate hydratase	16	0	0	16
PPM1D protein	11	0	0	11
polyprotein	16	0	0	16
Parkin	12	0	0	12
huntingtin isoform 2	7	0	0	7
ras-related protein Rab-9A	13	0	0	13
serine/threonine-protein kinase mTOR isoform 1	16	0	0	16
urokinase-type plasminogen activator precursor	14	0	0	14
plasminogen precursor	14	0	0	14
urokinase plasminogen activator surface receptor precursor	14	0	0	14
Interferon beta	24	0	0	24
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Adenosine receptor A2a	0	9	0	9
Adenosine receptor A1	0	7	0	7
D(1A) dopamine receptor	11	1	0	12
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	9	0	0	9
Rap guanine nucleotide exchange factor 3	7	0	0	7
Zinc finger protein mex-5	0	0	1	1
Genome polyprotein	0	1	0	1
Hexokinase-2	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
Endolysin	0	0	3	3
caspase-1 isoform alpha precursor	5	0	0	5
Inositol monophosphatase 1	10	0	0	10
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Solute carrier organic anion transporter family member 1B1	0	7	0	9
Carbonic anhydrase	0	8	0	13
Mcl-1	0	3	0	3
Muscarinic acetylcholine receptor M1	0	8	1	9
Muscarinic acetylcholine receptor M3	0	7	1	8
Muscarinic acetylcholine receptor M4	0	7	1	8
Muscarinic acetylcholine receptor M5	0	7	1	8
Muscarinic acetylcholine receptor M2	0	8	1	9
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	3	0	5
Thymidine phosphorylase	0	0	0	2
Thymidylate kinase	0	2	0	2
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	2	0	2
Cytochrome P450 2E1	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	12	0	0	12
Caspase-2	0	0	1	1
polyunsaturated fatty acid lipoxygenase ALOX12	7	0	0	7
nuclear factor NF-kappa-B p105 subunit isoform 1	6	0	0	6
heat shock protein HSP 90-alpha isoform 2	0	0	0	3
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
heat shock protein 90, putative	0	0	0	3
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	1	0	1
G	18	0	0	18
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	3	0	3
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	2	3	5
histone deacetylase 9 isoform 3	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	6	0	0	6
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	1	3	4
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
5-hydroxytryptamine receptor 4	0	14	0	14
Potassium channel subfamily K member 2	0	2	1	3
HLA class I histocompatibility antigen, B alpha chain	18	0	0	18
Albumin	0	4	4	9
Albumin	0	0	4	4
Major prion protein	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Receptor tyrosine-protein kinase erbB-2	0	4	1	5
Major prion protein	0	0	1	1
Procathepsin L	0	2	3	5
Muscarinic acetylcholine receptor M2	0	8	0	8
Muscarinic acetylcholine receptor M4	0	10	0	10
ATP-dependent translocase ABCB1	0	10	1	14
Muscarinic acetylcholine receptor M5	0	11	0	11
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	3	4	7
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Muscarinic acetylcholine receptor M1	0	13	0	13
Angiotensin-converting enzyme	0	7	0	7
Sphingomyelin phosphodiesterase	0	1	0	1
Muscarinic acetylcholine receptor M3	0	10	0	10
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	12	0	12
Adenylate cyclase type 3	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	0	0	3
Histamine H2 receptor	0	9	2	11
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	1	0	2
Trypanothione reductase	0	2	0	2
Histamine H1 receptor	0	3	2	5
Melanocortin receptor 4	0	4	0	4
Melanocortin receptor 5	0	6	0	6
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Histamine H1 receptor	0	8	2	10
Mu-type opioid receptor	0	14	2	16
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	4
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	8	1	9
Kappa-type opioid receptor	0	9	1	10
Melanocortin receptor 3	0	4	0	4
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Sodium-dependent dopamine transporter	0	17	2	19
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Aldehyde oxidase	0	4	0	4
Potassium voltage-gated channel subfamily H member 2	0	16	0	16
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Inositol hexakisphosphate kinase 1	18	0	0	18
Sodium channel protein type 2 subunit alpha	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	1	3	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	3	2	5
Sodium channel protein type 10 subunit alpha	0	2	0	2
cytochrome P450 2C9, partial	18	0	0	18
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-3	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Amyloid-beta precursor protein	1	6	0	8
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	4	11
Gamma-aminobutyric acid receptor subunit beta-1	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	3	10
Liver carboxylesterase 1	0	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	3	10
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit beta-2	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	2	9
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	2	9
Sodium-dependent dopamine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	5	0	5
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Nrf2	1	0	0	1
PINK1	4	0	0	4
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	2	0	2
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
transcriptional regulator ERG isoform 3	7	0	0	7
histone-lysine N-methyltransferase 2A isoform 2 precursor	10	0	0	10
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
muscleblind-like protein 1 isoform 1	7	0	0	7
hypothetical protein SA1422	0	1	0	1
neuropeptide S receptor isoform A	13	0	0	13
Prostaglandin E synthase	0	2	0	2
Acetylcholinesterase	0	3	0	3
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	2	0	2
Phospholipase A2	0	1	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cholinesterase	0	5	0	5
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
60 kDa chaperonin	0	3	0	3
Microtubule-associated protein tau	0	1	0	2
60 kDa heat shock protein, mitochondrial	0	3	0	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Heme oxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-synuclein	12	2	1	15
Glycogen synthase kinase-3 beta	0	2	2	4
Beta-secretase 1	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Serine/threonine-protein kinase PAK 1	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	1	2
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Thiosulfate sulfurtransferase	0	3	0	3
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
P53	1	0	0	1
RPL19A	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	9	0	0	9
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	1	2
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Lysine-specific demethylase 4A	0	1	0	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Sex hormone-binding globulin	0	0	2	2
Beta-glucuronidase	0	1	0	1
Corticosteroid-binding globulin	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
G-protein coupled bile acid receptor 1	0	0	2	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Taste receptor type 2 member 46	0	0	3	3
Cytochrome P450 2D4	0	1	0	1
Gamma-aminobutyric acid	0	2	1	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	1	1	0	2
Gastrin/cholecystokinin type B receptor	1	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	11	0	0	11
high affinity choline transporter 1 isoform a	0	1	0	1
Estrogen receptor	0	6	3	10
Beta-1 adrenergic receptor	0	8	1	9
Thromboxane-A synthase	0	4	0	4
Vasopressin V1a receptor	0	2	0	2
Estrogen-related receptor gamma	0	1	1	2
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	3	1	4
Estrogen receptor beta	0	5	3	8
Cysteinyl leukotriene receptor 1	0	2	0	2
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	2	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 6	0	3	0	5
Solute carrier family 22 member 7	0	0	0	3
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	4	0	5
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Ultraspiracle	0	4	0	4
20-hydroxy-ecdysone receptor	0	4	0	4
eyes absent homolog 2 isoform a	2	0	0	2
Ecdysone receptor	0	2	0	2
Protein ultraspiracle	0	1	0	1
Ecdysone receptor	0	2	0	2
Ultraspiracle	0	1	0	1
20-hydroxy-ecdysone receptor	0	1	0	1
Ultraspiracle protein	0	1	0	1
20-hydroxy-ecdysone receptor	0	1	0	1
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	4
UDP-glucuronosyltransferase 1A7	0	0	0	1
Eyes absent homolog 2	0	2	0	2
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Proenkephalin-B	0	0	1	1
Delta-type opioid receptor	0	2	1	5
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	4	0	4
Kappa-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	1	0	1
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
relaxin receptor 1 isoform 1	2	0	0	2
Flavin reductase (NADPH)	0	0	1	1
Vpr	3	0	0	3
Cytochrome P450 2B6	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
nonstructural protein 1	11	0	0	11
Cocaine esterase	0	2	0	3
Androgen receptor	0	4	1	6
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	2
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit rho-2	0	0	2	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	1	1	2
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 5	0	1	1	3
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Glycine receptor subunit alpha-1	0	2	1	3
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	6	0	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Estrogen receptor 1	0	2	0	2
DNA polymerase III, partial	2	0	0	2
galactokinase	2	0	0	2
hexokinase-4 isoform 1	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	9	0	0	9
glucokinase regulatory protein	4	0	0	4
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	3	0	3
tyrosine-protein kinase Yes	2	0	0	2
eukaryotic translation initiation factor 4E isoform 1	0	3	0	3
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase	2	0	0	2
Prolyl endopeptidase	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Beta-lactamase	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
Apoptosis regulator Bcl-2	0	2	1	3
Malate dehydrogenase, cytoplasmic	0	1	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
L-lactate dehydrogenase B chain	0	1	0	1
DNA-3-methyladenine glycosylase	0	1	0	1
Caspase-1	1	2	0	4
DNA repair protein RAD52 homolog	0	2	0	2
Kinesin-like protein KIF11	0	1	0	1
BH3-interacting domain death agonist	0	1	0	1
Type 1 InsP3 receptor isoform S2	1	0	0	1
Bcl-2-like protein 1	0	2	1	3
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	1	3
L-lactate dehydrogenase	0	1	0	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
L-lactate dehydrogenase	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
L-lactate dehydrogenase	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Histamine H3 receptor	1	0	0	1
phosphoglycerate kinase	4	0	0	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	3	0	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	2	2
Integrin beta-1	0	2	0	2
Beta-2 adrenergic receptor	0	4	1	5
Integrin alpha-4	0	2	0	2
Carbonyl reductase [NADPH] 1	0	0	0	1
Beta-1 adrenergic receptor	0	4	1	6
5-hydroxytryptamine receptor 3A	0	1	0	1
Beta-3 adrenergic receptor	0	2	1	3
Histamine H1 receptor	0	4	1	5
C-8 sterol isomerase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	1	4
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	2	0	2
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
calpain II, partial	0	1	0	1
PAX8	0	0	0	1
SUMO-1	0	1	0	1
Valosin-containing protein	0	1	0	1
TSHR protein	1	0	0	1
envelope glycoprotein	0	1	0	1
heat shock protein 90	0	0	1	1
heat shock 70kDa protein 1A	0	1	0	1
tumor necrosis factor	1	0	0	1
neuropeptide Y receptor type 1	0	0	1	1
neuropeptide Y receptor type 2	0	0	1	1
small ubiquitin-related modifier 2 isoform b precursor	0	1	0	1
estrogen receptor beta isoform 1	0	2	0	2
enteropeptidase precursor	1	0	0	1
fatty acid synthase	0	1	0	1
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
streptokinase A precursor	0	0	4	4
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Estrogen receptor	0	0	4	5
Urokinase-type plasminogen activator	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Macrophage migration inhibitory factor	0	5	0	5
Mitogen-activated protein kinase 3	0	1	1	2
Mitogen-activated protein kinase 1	0	1	1	2
Cytochrome P450 2C19	0	9	0	9
Estrogen receptor beta	0	0	4	5
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
Rap guanine nucleotide exchange factor 4	5	0	0	5
M1-family alanyl aminopeptidase	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
BZLF2	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	4	0	0	4
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase	0	0	0	6
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	6
Carbonic anhydrase	0	1	0	7
Carbonic anhydrase	0	0	0	6
Carbonic anhydrase	0	0	0	6
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	2
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
ClpP	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Progesterone receptor	0	2	0	2
Androgen receptor	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	3	0	3
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Prostaglandin G/H synthase 1	0	2	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Peptide deformylase 1A, chloroplastic/mitochondrial	0	1	0	1
Peptide deformylase	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	3
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Pantothenate synthetase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
NPYLR7B	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	2
Beta-2 adrenergic receptor	0	4	2	7
Beta-3 adrenergic receptor	0	3	1	4
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	2	3
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	3	0	0	3
SLC16A10 protein	0	0	0	4
Monocarboxylate transporter 10	0	0	0	4
inositol monophosphatase 1	1	0	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
bcl-2-related protein A1	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	2	0	2
Insulin receptor	0	1	0	1
Integrin alpha-L	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Cytochrome P450 1B1	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Tumor necrosis factor	0	2	0	2
Neuraminidase	0	1	0	1
Platelet-activating factor receptor	1	0	0	1
Cystathionine gamma-lyase	0	4	0	4
Protein-arginine deiminase type-4	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Hydroxyacid oxidase 1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	2	0	2
Nuclear receptor corepressor 2	0	3	0	3
5-hydroxytryptamine receptor 1B	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Formyl peptide receptor-related sequence 1	0	0	1	1
fMet-Leu-Phe receptor	0	2	2	4
N-formyl peptide receptor 2	0	0	2	2
FML2_HUMAN	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Neurotensin receptor type 1	0	0	1	1
Neurotensin receptor type 2	0	1	1	3
Myelin basic protein	0	0	1	1
Neurotensin receptor type 1	0	1	1	2
Neurotensin receptor type 1	0	2	2	5
Neurotensin receptor type 2	0	2	1	3
Sortilin	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Collagenase 3	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Glutamate dehydrogenase 1, mitochondrial	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	1	0	1
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
nonstructural protein 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	3	0	3
Amine oxidase [flavin-containing] A	0	2	0	2
Pyrroline-5-carboxylate reductase 1, mitochondrial	0	1	0	1
Renin	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
vasopressin V1b receptor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Chitotriosidase-1	0	2	1	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Endochitinase B1	0	2	1	3
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M4	0	0	1	2
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Phospholipase A-2-activating protein	0	2	0	2
Dihydrofolate reductase	0	1	0	1
luciferase	1	0	0	1
Luciferin 4-monooxygenase	0	1	1	2
ATP-binding cassette sub-family C member 9	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	1	0	1
P2X purinoceptor 4	0	0	1	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Pyridoxal kinase	0	0	0	1
D(2) dopamine receptor	0	2	0	2
ATP-dependent translocase ABCB1	0	1	0	1
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	3	1	4
Synaptic vesicular amine transporter	0	3	1	4
Synaptic vesicular amine transporter	0	2	0	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	1
Pteridine reductase 1	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (fumarate)	0	1	0	1
Acyl carrier protein, mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Serine/threonine-protein kinase PLK4	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Tyrosine-protein kinase JAK2	0	1	1	2
Bromodomain-containing protein 4	0	1	1	2
Ribosomal protein S6 kinase alpha-5	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	1	2	3
Cyclin-dependent kinase 14	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Tyrosinase	0	1	0	1
Fibroblast growth factor receptor 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Platelet-derived growth factor receptor alpha	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
Vascular endothelial growth factor receptor 1	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Tyrosine-protein kinase JAK1	0	1	1	2
Protein kinase C eta type	0	1	2	3
Cyclin-dependent kinase 2	0	0	1	1
Activin receptor type-2A	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Casein kinase I isoform delta	0	1	1	2
MAP kinase-activated protein kinase 2	0	0	1	1
Cyclin-dependent kinase 8	0	1	1	2
Casein kinase I isoform epsilon	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 12	0	1	1	2
Mitogen-activated protein kinase 10	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
Protein kinase C epsilon type	0	2	2	4
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
Angiopoietin-1 receptor	0	0	1	1
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Protein kinase C theta type	0	1	2	3
Activin receptor type-1	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	2	2	4
Tyrosine-protein kinase BTK	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Serine/threonine-protein kinase D1	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	1	1	2
Serine/threonine-protein kinase STK11	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Bromodomain testis-specific protein	0	1	0	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Tau-tubulin kinase 1	0	1	0	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Tau-tubulin kinase 2	0	1	0	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Myosin-IIIb	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Transcriptional activator protein LuxR	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Envelope glycoprotein	0	0	1	1
serine-protein kinase ATM isoform a	1	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
alternatively spliced Trp4	0	0	1	1
5-hydroxytryptamine receptor 1E	0	1	0	1
sphingosine 1-phosphate receptor 3	0	1	0	1
Beta-casein	0	1	0	1
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
D(4) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
Glycine receptor subunit beta	0	1	0	1
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	4	1	5
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Chain A, CES1 protein	0	1	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	2	1	3
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	2	1	3
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Protein kinase C alpha type	0	2	1	3
B2 bradykinin receptor	0	2	0	2
Protein kinase C iota type	0	1	1	2
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C zeta type	0	1	1	2
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Vitamin D3 receptor	0	2	1	3
Ephrin type-A receptor 2	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidylate synthase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Thymidine phosphorylase	0	1	0	1
Chain A, PAPAIN	1	0	0	1
TPA: protein transporter TIM23	0	1	0	1
protein-arginine deiminase type-4	0	1	0	1
chaperonin GroEL	1	0	0	1
Chymotrypsinogen A	0	1	0	1
Cathepsin G	0	1	0	1
Chymotrypsin-like elastase family member 2A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Chymase	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
unnamed protein product	0	0	0	1
Histone deacetylase 1	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Histone deacetylase 3	0	1	0	1
Adenosine receptor A1	0	1	0	1
Histone deacetylase 2	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Histone deacetylase 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Histone deacetylase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	0	2
Histone deacetylase 7	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	1	2
Histone deacetylase 8	0	1	0	1
Histone deacetylase 11	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 5	0	1	0	1
Histone deacetylase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Diamine acetyltransferase 1	0	0	0	1
Thialysine N-epsilon-acetyltransferase	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Receptor-type tyrosine-protein phosphatase F	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (892)

Protein Targets (1,860)

Manganese Poisoning

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (892)

Drugs Studied (371)

Protein Targets (1,860)