gamma-aminobutyric acid has been researched along with Manganese Poisoning in 20 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Manganese Poisoning: Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We review occupational Mn-induced parkinsonism and the dynamic modes of Mn transport in biological systems, as well as the detection and pharmacokinetic modeling of Mn trafficking." | 2.52 | Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features. ( Aschner, M; Bowman, AB; Kwakye, GF; Mukhopadhyay, S; Paoliello, MM, 2015) |
| " Here, a collection of subchronic to chronic rodent and nonhuman primate studies was evaluated to determine whether there is a consistent dose-response relationship among studies, whether there is a progression of effects with increasing dose, and whether these studies are adequate for evaluating the neurotoxicity of chronic low-level manganese exposures in humans." | 2.44 | Adequacy and consistency of animal studies to evaluate the neurotoxicity of chronic low-level manganese exposure in humans. ( Gwiazda, R; Lucchini, R; Smith, D, 2007) |
| "Manganese (Mn) is a well established neurotoxin associated with specific damage to the basal ganglia in humans." | 1.38 | Pathophysiology of manganese-associated neurotoxicity. ( Aschner, M; Criswell, SR; Dydak, U; Guilarte, TR; Racette, BA; Zheng, W, 2012) |
| "Manganese (Mn) is an essential element and it acts as a cofactor for a number of enzymatic reactions, including those involved in amino acid, lipid, protein, and carbohydrate metabolism." | 1.38 | Manganese alters rat brain amino acids levels. ( Almeida, I; Aschner, M; Batoreu, MC; Marreilha dos Santos, AP; Ramos, R; Santos, D; Sidoryk-Wegrzynowicz, M, 2012) |
| "Manganese is an essential nutrient, integral to proper metabolism of amino acids, proteins and lipids." | 1.35 | Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia. ( Anderson, DJ; Aschner, M; Fitsanakis, VA; Leitch, DB; McLaughlin, B; Savchenko, V; Stankowski, JN; Stanwood, GD; Wu, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, SJ | 1 |
| Ou, CY | 1 |
| He, SN | 1 |
| Huang, XW | 1 |
| Luo, HL | 1 |
| Meng, HY | 1 |
| Lu, GD | 1 |
| Jiang, YM | 1 |
| Vieira Peres, T | 1 |
| Luo, YN | 1 |
| Deng, XF | 1 |
| Ma, RE | 1 |
| Ward, EJ | 1 |
| Yeh, CL | 1 |
| Snyder, S | 1 |
| Long, Z | 1 |
| Gokalp Yavuz, F | 1 |
| Zauber, SE | 1 |
| Dydak, U | 2 |
| Kikuchihara, Y | 1 |
| Abe, H | 1 |
| Tanaka, T | 1 |
| Kato, M | 1 |
| Wang, L | 1 |
| Ikarashi, Y | 1 |
| Yoshida, T | 1 |
| Shibutani, M | 1 |
| Kwakye, GF | 1 |
| Paoliello, MM | 1 |
| Mukhopadhyay, S | 1 |
| Bowman, AB | 1 |
| Aschner, M | 5 |
| Stanwood, GD | 1 |
| Leitch, DB | 1 |
| Savchenko, V | 1 |
| Wu, J | 1 |
| Fitsanakis, VA | 2 |
| Anderson, DJ | 1 |
| Stankowski, JN | 1 |
| McLaughlin, B | 1 |
| Burton, NC | 1 |
| Schneider, JS | 1 |
| Syversen, T | 1 |
| Guilarte, TR | 2 |
| Just, N | 1 |
| Cudalbu, C | 1 |
| Lei, H | 1 |
| Gruetter, R | 1 |
| Yang, Y | 1 |
| An, J | 1 |
| Wang, Y | 1 |
| Luo, W | 1 |
| Wang, W | 1 |
| Mei, X | 1 |
| Wu, S | 1 |
| Chen, J | 1 |
| Racette, BA | 1 |
| Criswell, SR | 1 |
| Zheng, W | 1 |
| Santos, D | 1 |
| Batoreu, MC | 1 |
| Almeida, I | 1 |
| Ramos, R | 1 |
| Sidoryk-Wegrzynowicz, M | 1 |
| Marreilha dos Santos, AP | 1 |
| Zwingmann, C | 1 |
| Leibfritz, D | 1 |
| Hazell, AS | 1 |
| Liu, X | 1 |
| Sullivan, KA | 1 |
| Madl, JE | 1 |
| Legare, M | 1 |
| Tjalkens, RB | 1 |
| Crooks, DR | 1 |
| Welch, N | 1 |
| Smith, DR | 1 |
| Gwiazda, R | 1 |
| Lucchini, R | 1 |
| Smith, D | 1 |
| Gianutsos, G | 1 |
| Murray, MT | 1 |
| Chandra, SV | 1 |
| Malhotra, KM | 1 |
| Shukla, GS | 1 |
| Defazio, G | 1 |
| Soleo, L | 1 |
| Zefferino, R | 1 |
| Livrea, P | 1 |
| Kosicka, B | 2 |
| Kittel, M | 2 |
| Smiałek, M | 2 |
| Bugera, TE | 1 |
3 reviews available for gamma-aminobutyric acid and Manganese Poisoning
| Article | Year |
|---|---|
Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features.
Topics: Brain; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnesium; Manganese Poisoning; Par | 2015 |
The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity.
Topics: Animals; Biological Transport; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Kidney Disea | 2005 |
Adequacy and consistency of animal studies to evaluate the neurotoxicity of chronic low-level manganese exposure in humans.
Topics: Animals; Corpus Striatum; Dose-Response Relationship, Drug; Environmental Pollutants; gamma-Aminobut | 2007 |
17 other studies available for gamma-aminobutyric acid and Manganese Poisoning
| Article | Year |
|---|---|
Sodium p-Aminosalicylic Acid Reverses Sub-Chronic Manganese-Induced Impairments of Spatial Learning and Memory Abilities in Rats, but Fails to Restore γ-Aminobutyric Acid Levels.
Topics: Aminosalicylic Acid; Animals; Drug Administration Schedule; gamma-Aminobutyric Acid; Male; Manganese | 2017 |
Thalamic GABA levels and occupational manganese neurotoxicity: Association with exposure levels and brain MRI.
Topics: Adult; Air Pollutants, Occupational; Brain; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spec | 2018 |
Relationship between brain accumulation of manganese and aberration of hippocampal adult neurogenesis after oral exposure to manganese chloride in mice.
Topics: Administration, Oral; Animals; Biomarkers; Brain-Derived Neurotrophic Factor; Chlorides; GABAergic N | 2015 |
Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia.
Topics: Animals; Basal Ganglia; Cytoskeleton; Dopamine; Endoplasmic Reticulum; gamma-Aminobutyric Acid; Glut | 2009 |
Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain.
Topics: Animals; Astrocytes; Autoradiography; Biomarkers; Brain Chemistry; Chromatography, High Pressure Liq | 2009 |
Effect of manganese chloride on the neurochemical profile of the rat hypothalamus.
Topics: Amino Acids; Animals; Anorexia; Chlorides; Dehydration; Energy Metabolism; Female; gamma-Aminobutyri | 2011 |
Intrastriatal manganese chloride exposure causes acute locomotor impairment as well as partial activation of substantia nigra GABAergic neurons.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Chlorides; Corpus Striatum; Dopamine; Fluo | 2011 |
Pathophysiology of manganese-associated neurotoxicity.
Topics: Air Pollutants, Occupational; Animals; Aspartic Acid; Brain; Dopamine; gamma-Aminobutyric Acid; Huma | 2012 |
Manganese alters rat brain amino acids levels.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Chlorides; Dose-Response Relationship, Drug; Extrapyra | 2012 |
Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose.
Topics: Animals; Blood Glucose; Brain; Carbon Isotopes; Disease Models, Animal; Energy Metabolism; gamma-Ami | 2004 |
Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degeneration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Brain; Disease Models, Animal; Dopamine; Female | 2006 |
Low-level manganese exposure alters glutamate metabolism in GABAergic AF5 cells.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Cell Line; Culture Media; Extracellular Space; g | 2007 |
Alterations in brain dopamine and GABA following inorganic or organic manganese administration.
Topics: Animals; Brain; Brain Chemistry; Choline O-Acetyltransferase; Dopamine; gamma-Aminobutyric Acid; Mal | 1982 |
GABAergic neurochemistry in manganese exposed rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male | 1982 |
Manganese toxicity in serumless dissociated mesencephalic and striatal primary culture.
Topics: Animals; Biomarkers; Cells, Cultured; Corpus Striatum; Culture Media, Serum-Free; gamma-Aminobutyric | 1996 |
[Effect of manganese chloride poisoning during pregnancy and lactation on the levels and synthesis of gamma-aminobutyric acid (GABA) in the rat brain].
Topics: Animals; Brain Chemistry; Chlorides; Female; gamma-Aminobutyric Acid; Lactation; Male; Manganese Com | 1985 |
[Gamma-aminobutyric acid (GABA) levels and glutamate decarboxylase (GAD) activity of the brain of rats with extrapyramidal syndrome after acute manganese chloride poisoning].
Topics: Acute Disease; Brain Chemistry; Chlorides; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; | 1985 |