aminosalicylic acid has been researched along with Manganese Poisoning in 12 studies
Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
4-aminosalicylic acid : An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.
Manganese Poisoning: Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two cases of chronic manganese poisoning were treated with sodium para-aminosalicylic acid (PAS-Na; 6 g/day in 500 ml of 10% glucose solution by intravenous drip)." | 7.68 | A report of two cases of chronic serious manganese poisoning treated with sodium para-aminosalicylic acid. ( Deng, HS; Hu, W; Ky, SQ; Xie, PY, 1992) |
| "Two cases of chronic manganese poisoning were treated with sodium para-aminosalicylic acid (PAS-Na; 6 g/day in 500 ml of 10% glucose solution by intravenous drip)." | 3.68 | A report of two cases of chronic serious manganese poisoning treated with sodium para-aminosalicylic acid. ( Deng, HS; Hu, W; Ky, SQ; Xie, PY, 1992) |
| "Manganese (Mn) is an essential metal for biological systems; however, occupational or clinical exposure to high levels of Mn can produce a neurological disorder called manganism." | 1.39 | Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity. ( Aschner, M; Batoreu, MC; Marreilha dos Santos, AP; Santos, D, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Y | 1 |
| Peng, D | 1 |
| Yang, C | 1 |
| Zhao, L | 1 |
| Li, J | 1 |
| Lu, L | 1 |
| Zhu, X | 1 |
| Li, S | 1 |
| Aschner, M | 2 |
| Jiang, Y | 1 |
| Li, SJ | 4 |
| Ou, CY | 3 |
| He, SN | 1 |
| Huang, XW | 2 |
| Luo, HL | 2 |
| Meng, HY | 2 |
| Lu, GD | 2 |
| Jiang, YM | 7 |
| Vieira Peres, T | 1 |
| Luo, YN | 3 |
| Deng, XF | 3 |
| Fu, X | 2 |
| Chen, JW | 3 |
| Huang, S | 1 |
| Huang, YS | 1 |
| Ou, SY | 3 |
| Li, Y | 2 |
| Yuan, ZX | 2 |
| Mo, YH | 2 |
| Wang, F | 1 |
| Huang, YN | 1 |
| Zheng, W | 2 |
| Zhang, Y | 1 |
| Jiang, W | 1 |
| Wang, X | 1 |
| Cowan, DM | 1 |
| Nelson, M | 1 |
| Huggins, T | 1 |
| Licorish, R | 1 |
| Carroll, MA | 1 |
| Catapane, EJ | 1 |
| Qin, WP | 1 |
| Liang, TJ | 1 |
| Santos, D | 1 |
| Batoreu, MC | 1 |
| Marreilha dos Santos, AP | 1 |
| Mo, XA | 1 |
| Du, FQ | 1 |
| Zhu, XY | 1 |
| Gao, HY | 1 |
| Xie, JL | 1 |
| Liao, FL | 1 |
| Pira, E | 1 |
| Tandon, SK | 1 |
| Ky, SQ | 1 |
| Deng, HS | 1 |
| Xie, PY | 1 |
| Hu, W | 1 |
12 other studies available for aminosalicylic acid and Manganese Poisoning
| Article | Year |
|---|---|
Preventive treatment with sodium para-aminosalicylic acid inhibits manganese-induced apoptosis and inflammation
Topics: Aminosalicylic Acid; Animals; Apoptosis; Caspase 3; Cyclooxygenase 2; Inflammation; Manganese; Manga | 2023 |
Sodium p-Aminosalicylic Acid Reverses Sub-Chronic Manganese-Induced Impairments of Spatial Learning and Memory Abilities in Rats, but Fails to Restore γ-Aminobutyric Acid Levels.
Topics: Aminosalicylic Acid; Animals; Drug Administration Schedule; gamma-Aminobutyric Acid; Male; Manganese | 2017 |
Protective effects of sodium p-aminosalicylic acid on learning and memory via increasing the number of basal forebrain choline acetyltransferase neurons in manganese-exposed rats.
Topics: Aminosalicylic Acid; Animals; Basal Forebrain; Choline O-Acetyltransferase; Cognition Disorders; Lea | 2015 |
Sodium Para-aminosalicylic Acid Protected Primary Cultured Basal Ganglia Neurons of Rat from Manganese-Induced Oxidative Impairment and Changes of Amino Acid Neurotransmitters.
Topics: Aminosalicylic Acid; Animals; Basal Ganglia; Cells, Cultured; Manganese; Manganese Poisoning; Neuron | 2016 |
Sodium para-aminosalicylate protected cultured basal ganglia astrocytes from manganese-induced DNA damages and alteration of amino acid neurotransmitter levels.
Topics: Aminosalicylic Acid; Animals; Animals, Newborn; Astrocytes; Basal Ganglia; Cells, Cultured; Chloride | 2016 |
Chelation therapy of manganese intoxication with para-aminosalicylic acid (PAS) in Sprague-Dawley rats.
Topics: Aminosalicylic Acid; Animals; Chelation Therapy; Male; Manganese; Manganese Poisoning; Rats; Rats, S | 2009 |
Effects of p-Aminosalicylic acid on the neurotoxicity of manganese on the dopaminergic innervation of the cilia of the lateral cells of the gill of the bivalve mollusc, Crassostrea virginica.
Topics: Aminosalicylic Acid; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitub | 2010 |
[A chronic moderate manganism poisoning treated with sodium p-aminosalicylic acid].
Topics: Adult; Aminosalicylic Acid; Female; Humans; Manganese Poisoning | 2011 |
Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity.
Topics: Aminosalicylic Acid; Analysis of Variance; Animals; Brain; Cell Line; Cell Survival; Chlorides; Dose | 2013 |
Effective treatment of manganese-induced occupational Parkinsonism with p-aminosalicylic acid: a case of 17-year follow-up study.
Topics: Aminosalicylic Acid; Disease Progression; Female; Follow-Up Studies; Humans; Manganese Poisoning; Mi | 2006 |
Chelation in metal intoxication. VI. Influence of PAS and CDTA on the excretion of manganese in rabbits given MnO2.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Chelating Agents; Drug Therapy, Combination; Ede | 1978 |
A report of two cases of chronic serious manganese poisoning treated with sodium para-aminosalicylic acid.
Topics: Aminosalicylic Acid; Chronic Disease; Female; Humans; Male; Manganese Poisoning; Middle Aged; Occupa | 1992 |