N(3)-ethylthymidine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 159912 |
| CHEMBL ID | 3229791 |
| SCHEMBL ID | 2056832 |
| MeSH ID | M0183036 |
| Synonym |
|---|
| n3-ethylthymidine |
| thymidine, 3-ethyl- |
| 21473-40-5 |
| n(3)-ethylthymidine |
| n3-et-dt |
| n3-ethyldeoxythymidine |
| CHEMBL3229791 |
| SCHEMBL2056832 |
| DTXSID10175758 |
| 3-ethylthymidine |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1136938 | Non-competitive inhibition of Escherichia coli B thymidine kinase using [2-14C]-thymidine as substrate assessed as formation of [14C]-TMP after 10 mins by Lineweaver-Burk double reciprocal plot analysis | 1979 | Journal of medicinal chemistry, Dec, Volume: 22, Issue:12 | Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site. |
| AID1136932 | Inhibition of Escherichia coli B thymidine kinase using [2-14C]-thymidine as substrate assessed as formation of [14C]-TMP at 0.5 mM after 10 mins by liquid scintillation spectrometric analysis relative to control | 1979 | Journal of medicinal chemistry, Dec, Volume: 22, Issue:12 | Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site. |
| AID1124531 | Inhibition of thymidine kinase in BHK21 (C13) cells using thymidine as substrate assessed as formation of TMP at 0.2 mM | 1979 | Journal of medicinal chemistry, Jun, Volume: 22, Issue:6 | Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase. |
| AID1136934 | Inhibition of Escherichia coli B thymidine kinase using [2-14C]-thymidine as substrate assessed as formation of [14C]-TMP at 1 mM after 10 mins by liquid scintillation spectrometric analysis relative to control | 1979 | Journal of medicinal chemistry, Dec, Volume: 22, Issue:12 | Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site. |
| AID1124530 | Inhibition of thymidine kinase in BHK21 (C13) cells using thymidine as substrate assessed as formation of TMP at 0.1 mM | 1979 | Journal of medicinal chemistry, Jun, Volume: 22, Issue:6 | Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.13) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||