pinacidil has been researched along with Manganese Poisoning in 1 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Manganese Poisoning: Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further investigation indicated that pre-treatment of pinacidil or nimodipine reversed toxic effect of MnCl(2) significantly." | 1.35 | Excitotoxicity in rat's brain induced by exposure of manganese and neuroprotective effects of pinacidil and nimodipine. ( Deng, X; Deng, Y; Gao, J; Tian, Y; Xin, X; Xu, B; Xu, Z, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Y | 1 |
| Xu, Z | 1 |
| Xu, B | 1 |
| Tian, Y | 1 |
| Deng, X | 1 |
| Xin, X | 1 |
| Gao, J | 1 |
1 other study available for pinacidil and Manganese Poisoning
| Article | Year |
|---|---|
Excitotoxicity in rat's brain induced by exposure of manganese and neuroprotective effects of pinacidil and nimodipine.
Topics: Animals; Chlorides; Corpus Striatum; Dose-Response Relationship, Drug; Female; Male; Manganese Compo | 2009 |