Page last updated: 2024-10-25

amphetamine and Manganese Poisoning

amphetamine has been researched along with Manganese Poisoning in 2 studies

Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.

Manganese Poisoning: Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)

Research Excerpts

ExcerptRelevanceReference
" Results of studies to evaluate the effect of Mn and DA on cell viability in control and DAT-transfected HEK cells reveal that Mn is equally toxic to both cell lines whereas DA was only toxic to cells containing DAT."1.39The effect of manganese on dopamine toxicity and dopamine transporter (DAT) in control and DAT transfected HEK cells. ( Khoshbouei, H; Li, Z; Roth, JA; Sridhar, S, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roth, JA1
Li, Z1
Sridhar, S1
Khoshbouei, H1
McDougall, SA1
Reichel, CM1
Farley, CM1
Flesher, MM1
Der-Ghazarian, T1
Cortez, AM1
Wacan, JJ1
Martinez, CE1
Varela, FA1
Butt, AE1
Crawford, CA1

Other Studies

2 other studies available for amphetamine and Manganese Poisoning

ArticleYear
The effect of manganese on dopamine toxicity and dopamine transporter (DAT) in control and DAT transfected HEK cells.
    Neurotoxicology, 2013, Volume: 35

    Topics: Amphetamine; Cell Survival; Chlorides; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-R

2013
Postnatal manganese exposure alters dopamine transporter function in adult rats: Potential impact on nonassociative and associative processes.
    Neuroscience, 2008, Jun-23, Volume: 154, Issue:2

    Topics: Amphetamine; Animals; Animals, Newborn; Association Learning; Body Weight; Central Nervous System St

2008