spiperone has been researched along with Manganese Poisoning in 3 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Manganese Poisoning: Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include CONFUSION; HALLUCINATIONS; and an extrapyramidal syndrome (PARKINSON DISEASE, SECONDARY) that includes rigidity; DYSTONIA; retropulsion; and TREMOR. (Adams, Principles of Neurology, 6th ed, p1213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies suggest that chronic administration of manganese produces symptoms akin to Parkinson's disease, which is believed to be due to derangement in the central cholinergic and dopaminergic system." | 1.27 | Effect of repeated administration of manganese on the striatal cholinergic and dopaminergic receptors in the rat. ( Bhargava, HN, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seth, PK | 1 |
| Chandra, SV | 1 |
| Bhargava, HN | 1 |
| Leung, TK | 1 |
| Lai, JC | 1 |
| Lim, L | 1 |
3 other studies available for spiperone and Manganese Poisoning
| Article | Year |
|---|---|
Neurotransmitters and neurotransmitter receptors in developing and adult rats during manganese poisoning.
Topics: Aging; Animals; Animals, Newborn; Biogenic Amines; Cerebellum; Haplorhini; Manganese Poisoning; Musc | 1984 |
Effect of repeated administration of manganese on the striatal cholinergic and dopaminergic receptors in the rat.
Topics: Animals; Binding Sites; Corpus Striatum; Injections, Intraperitoneal; Male; Manganese Poisoning; Qui | 1987 |
[3H]spiperone and [3H]quinuclidinyl benzilate binding in striatal membranes from rats chronically treated with manganese chloride throughout development and for over two years.
Topics: Age Factors; Animals; Chlorides; Corpus Striatum; In Vitro Techniques; Male; Manganese Compounds; Ma | 1986 |