amyloid-beta-peptides has been researched along with Manganese-Poisoning* in 1 studies
1 other study(ies) available for amyloid-beta-peptides and Manganese-Poisoning
Article | Year |
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The gut microbiota attenuate neuroinflammation in manganese exposure by inhibiting cerebral NLRP3 inflammasome.
Manganese (Mn) exposure has been reported to cause neurodegenerative disorders. β-Amyloid (Aβ) induced Tau pathology in an NLRP3-dependent manner is at the heart of Alzheimer's and Parkinson's diseases. The gut microbiota plays a crucial role in the bidirectional gut-brain axis that integrates the gut and central nervous system (CNS) activities. In this study, we found that Mn exposure increases Aβ Topics: Amyloid beta-Peptides; Animals; Cerebral Cortex; Cytokines; Disease Models, Animal; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Inflammasomes; Intestines; Male; Manganese Poisoning; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Rats, Sprague-Dawley; tau Proteins | 2020 |