thromboplastin and Giant-Cell-Arteritis

thromboplastin has been researched along with Giant-Cell-Arteritis* in 1 studies

Other Studies

1 other study(ies) available for thromboplastin and Giant-Cell-Arteritis

Article	Year
Leukocyte and platelet activation in patients with giant cell arteritis and polymyalgia rheumatica: a clue to thromboembolic risks? Autoimmunity, 2009, Volume: 42, Issue:4 Ischemia is a leading causes of morbidity in giant cell arteritis (GCA). We studied circulating platelets and leukocytes in patients with GCA and with polymyalgia rheumatica. Normal healthy donors (>60 a) served as controls. Patients had a significantly greater fraction of platelets expressing P-selectin, of platelet-Nph and platelet-Mo aggregates, and of Nph and Mo expressing tissue factor. These differences were correlated with the percentage of platelets expressing P-selectin and were not influenced by clinical features or by systemic inflammation. Activated circulating leukocytes and platelets could contribute to indolent vessel inflammation and possibly to thromboembolic events in patients with systemic large vessel vasculitis. Topics: Aged; Blood Platelets; Giant Cell Arteritis; Humans; Inflammation; Leukocytes; Middle Aged; P-Selectin; Platelet Activation; Polymyalgia Rheumatica; Risk Factors; Thromboembolism; Thromboplastin	2009

Article

Year

Leukocyte and platelet activation in patients with giant cell arteritis and polymyalgia rheumatica: a clue to thromboembolic risks?

Autoimmunity, 2009, Volume: 42, Issue:4

Ischemia is a leading causes of morbidity in giant cell arteritis (GCA). We studied circulating platelets and leukocytes in patients with GCA and with polymyalgia rheumatica. Normal healthy donors (>60 a) served as controls. Patients had a significantly greater fraction of platelets expressing P-selectin, of platelet-Nph and platelet-Mo aggregates, and of Nph and Mo expressing tissue factor. These differences were correlated with the percentage of platelets expressing P-selectin and were not influenced by clinical features or by systemic inflammation. Activated circulating leukocytes and platelets could contribute to indolent vessel inflammation and possibly to thromboembolic events in patients with systemic large vessel vasculitis.

Topics: Aged; Blood Platelets; Giant Cell Arteritis; Humans; Inflammation; Leukocytes; Middle Aged; P-Selectin; Platelet Activation; Polymyalgia Rheumatica; Risk Factors; Thromboembolism; Thromboplastin

2009