"lipacidemia and ketosis) are prevented." | ( Anschütz, A; Förster, H; Quadbeck, R, 1979) |
"Thus, ketosis is viewed as the result of increased mobilization of free fatty acids from adipose tissue (site 1) to the liver (site 2), coupled with simultaneous enhancement of the liver's capacity to convert these substrates into acetoacetic and beta-hydroxybutyric acids." | ( Foster, DW; McGarry, JD, 1977) |
"Post-exercise ketosis is known to be suppressed by physical training and by a high carbohydrate diet." | ( Adams, JH; Koeslag, JH, 1989) |
"Post-exercise ketosis is not abolished by glucose ingestion immediately after exercise but is counteracted by simultaneous beta-adrenergic blockade." | ( J de V Lochner, J; Koeslag, JH; Vahed, YA, 1988) |
"Diabetic ketoacidosis is often associated with a temporary increase in protein excretion, but the mechanisms are not completely known." | ( Alberti, KG; Christensen, CK; Mogensen, CE; Pedersen, EB; Schmitz, O, 1986) |
"A mild ketosis is known to prevail in the mother, fetus, and newborn infant during the 3rd trimester and in the early neonatal period." | ( Auestad, N; Benson, J; Edmond, J; Picone, T; Rambathla, S; Wu, PY, 1986) |
"No other cause of ketoacidosis is found." | ( Armaghanian, C; Didier, G; Fogliani, J; Fogliani, S, 1980) |
"Susceptibility to ketosis is probably due to the combination of appetite limitation and a high degree of precedence given to the demand of the mammary gland for nutrients, in particular glucose." | ( Baird, GD, 1982) |
"Ketosis is normal during fasting, after prolonged exercise, and when a high-fat diet is consumed." | ( Ashmarina, L; Boukaftane, Y; Kassovska-Bratinova, S; Lambert, M; Lapierre, P; Mitchell, GA; Potier, E; Robert, MF; Wang, SP, 1995) |
"Alcoholic ketoacidosis is rare and must be considered in the differential diagnosis of any alcoholic patient with acidosis." | ( Jobard, JM, 1993) |
"Ketosis is beneficial for seizure control, possibly through induction of cerebral acidosis." | ( Al-Mudallal, AS; Harik, SI; LaManna, JC; Lust, WD, 1996) |
"Although ketosis is an integral aspect of these therapeutic regimens, the direct importance of ketosis to seizure control needs further investigation." | ( Comeau, F; Cunnane, S; Curtis, R; Musa-Veloso, K; Rarama, E, 2002) |
"Ketosis is believed to be necessary to the anticonvulsant mechanism of the ketogenic diet; however, the relationship between ketosis and seizure control has not been established." | ( Musa-Veloso, K, 2004) |
"Thus, ketosis is insufficient and a functioning leptin signaling system appears necessary for the KD to slow weight gain." | ( Erbayat-Altay, E; Rensing, N; Thio, LL; Yamada, KA, 2006) |
"Subclinical ketosis is a metabolic disorder in high-producing dairy cattle that can be detected by ketone bodies in milk: acetone (Ac), acetoacetate (AcAc), and beta-hydroxybutyrate (BHBA)." | ( de Jong, G; de Roos, AP; Hørlyk, J; van den Bijgaart, HJ, 2007) |
"Ketosis is a common metabolic disease, and affected dairy cows are known to have increased risk for mastitis and other infectious conditions." | ( Elazar, S; Grinberg, N; Rosenshine, I; Shpigel, NY, 2008) |
"Hyperketonemia is increasingly being identified in type 2 diabetic patients in addition to those with type 1 diabetes." | ( Jain, SK; Rains, JL, 2011) |
"Physiological ketosis is a hallmark of metabolism in suckling infants." | ( Khazipov, R; Minlebaev, M, 2011) |
"Ketosis is a common metabolic disease in dairy cows." | ( Buttchereit, N; Gronwald, W; Immervoll, AK; Junge, W; Klein, MS; Louis, C; Miemczyk, SP; Oefner, PJ; Thaller, G; Wiedemann, S, 2012) |
"Ketosis is a metabolic disorder closely associated with both lipid and carbohydrate metabolism." | ( Sun, ZL; Xiao, HB; Zhou, N, 2012) |
"Alcohol ketoacidosis is a frequently missed diagnosis, but is well described in the literature." | ( Dwyer, JB; Tamama, K, 2013) |
"This degree of ketonemia is estimated to contribute up to 8% to 9% of brain energy metabolism." | ( Castellano, CA; Chouinard-Watkins, R; Courchesne-Loyer, A; Cunnane, SC; Fortier, M; Nugent, S; Roy, M; Tremblay-Mercier, J, 2013) |
"Ketosis is estimated to affect 15% of early lactation dairy cows." | ( Gordon, JL; Karcher, EL; Shire, J, 2013) |
"Subclinical ketosis is a metabolic disorder which often goes undiagnosed and leads to constricted performance and an impairment of general condition." | ( Dänicke, S; Frahm, J; Kersten, S; Meyer, U; Rehage, J; Reiche, D; Schulz, K, 2014) |
"KME-induced hyperketonemia is robust, convenient, and safe, and the ester can be taken as an oral supplement without changing the habitual diet." | ( Kashiwaya, Y; King, MT; Newport, MT; VanItallie, TB; Veech, RL, 2015) |
"Subclinical ketosis is one of the most prevalent metabolic disorders in high-producing dairy cows during early lactation." | ( Ehret, A; Gronwald, W; Hochstuhl, D; Klein, MS; Krattenmacher, N; Tetens, J; Thaller, G, 2015) |
"Ketosis is a common disease in dairy cattle, especially in the days after calving, and it is often undiagnosed." | ( Huzzey, JM; Itle, AJ; von Keyserlingk, MA; Weary, DM, 2015) |
"Ketosis is associated with many transition cow diseases and the subclinical form has been found to be a common condition in high-producing dairy cows." | ( Bemers, R; Berge, AC; Papen, J; Vanholder, T; Vertenten, G, 2015) |
"Subclinical ketosis is common and is significantly associated with reproductive performance in mainly pasture-fed New Zealand dairy cattle." | ( Compton, CW; McDougall, S; Young, L, 2015) |
"Ketosis is also produced during fasting periods, which is known as fasting ketosis (FK)." | ( Forzani, ES; Jackemeyer, D; Prabhakar, A; Quach, A; Tao, N; Terrera, M; Tsow, F; Xian, X; Zhang, H, 2015) |
"Ketoacidosis is a potential complication of type 1 diabetes." | ( Häring, HU; Heni, M; Hudak, SK; Overkamp, D; Wagner, R, 2015) |
"If alcoholic ketoacidosis is suspected, dextrose-containing fluids are recommended over normal saline." | ( Adkins, DA; Cook, AM; Flannery, AH, 2016) |
"Hyperketonemia is a condition with elevated blood levels of acetoacetate, 3-β-hydroxybutyrate, and acetone." | ( Jain, SK; Kanikarla-Marie, P, 2016) |
"Starvation ketoacidosis is a rare cause of metabolic acidosis and is a phenomenon that occurs normally during fasting, as the body switches from carbohydrate to lipid energy sources." | ( Augsburger, M; Burkhardt, S; Lardi, C; Palmiere, C; Sabatasso, S; Tettamanti, C; Werner, D, 2016) |
"Ketoacidosis is an important but under-recognized complication of neuromuscular disease, in particular spinal muscular atrophy." | ( Furlong, MJ; Gleeson, S; Mulroy, E, 2016) |
"Dairy cows with ketosis are characterized by oxidative stress, hepatic damage, and hyperketonemia." | ( Du, X; Li, X; Liu, G; Peng, Z; Shi, Z; Wang, Z; Zhang, Y; Zhao, C, 2017) |
"Ketosis is a very frequent metabolic disease in dairy cows, resulting in lower milk production, impaired fertility and increased frequency of other diseases." | ( Belić, B; Cincović, MR; Djoković, R; Ježek, J; Klinkon, M; Nemec, M; Starič, J, 2017) |
"Ketosis is a common condition found in the initial stages of lactation in high-yielding dairy cows." | ( Brodzki, A; Brodzki, P; Kurek, Ł; Marczuk, J, 2018) |
"Ketoacidosis is an under-recognized entity in patients with neuromuscular diseases and requires a high index of suspicion for prompt diagnosis and management." | ( El Chediak, A; Hashash, JG; Koubar, SH; Lakkis, B, 2018) |
"Neuroprotection by ketosis is thought to be associated with improved mitochondrial function, decreased reactive oxygen species (ROS) and apoptotic and inflammatory mediators, and increased protective pathways." | ( Kerwin, T; LaManna, JC; Puchowicz, M; Xu, K; Zhang, Y, 2018) |
"Subclinical ketosis is a common metabolic disorder affecting dairy cattle that results in a greater risk for the development of subsequent metabolic and infectious disease." | ( Duffield, TF; Kelton, DF; Renaud, DL, 2019) |
"Ketoacidosis is attributed in part to the massive release of ketone bodies (e." | ( Kaphalia, BS; Segar, L; Shawky, NM; Srinivasan, MP; Thangaraju, M, 2019) |
"Ketosis is a metabolic disorder that has an important impact on health and productivity in dairy cattle during early lactation." | ( Garzón-Audor, A; Oliver-Espinosa, O, 2019) |
"Ketoacidosis is uncommon in non-diabetic women, but occurs in the postpartum period as a rare complication of continuing to breastfeed during periods of acute illness." | ( Azzam, O; Prentice, D, 2019) |
"Diabetic ketoacidosis is defined as hyperglycemia >250 mg/dL with metabolic acidosis of arterial pH <7." | ( Bennett, A; Geehan, D; Moncure, M; Segebrecht, R; Van Way, CW; Weide, L, 2019) |
"Ketosis is a condition where ketone bodies are produced as an alternative energy source, due to insufficient glucose for energy production so that the body switches from carbohydrate metabolism to mostly fat metabolism." | ( Do Park, K; Kang, DY; Lee, HK; Song, KD; Sp, N; Yang, YM, 2019) |
"Ketosis is a major metabolic disorder of high-yielding dairy cows during the transition period." | ( Coleman, DN; Jia, H; Li, X; Liu, G; Loor, JJ; Ma, L; Wang, Y; Xu, C; Xu, Q, 2019) |
"Ketosis is a metabolic state in which the body uses ketones derived from breakdown of fatty acids as the primary mitochondrial fuel source instead of glucose." | ( Campbell, H; Campbell, I, 2019) |
"Ketosis is an important metabolic disease that can negatively affect the production efficiency of dairy cows." | ( Du, X; Fang, Z; Li, X; Liu, G; Loor, JJ; Shen, T; Shi, Z; Wang, X; Xing, D; Zhu, Y, 2019) |
"Ketoacidosis is a dangerous complication of diabetes mellitus in which plasma levels of ketone bodies can reach 20-25 mM." | ( Adamovich, KV; Adamovich, TV; Dubouskaya, TG; Fedorovich, SV; Hrynevich, SV; Voronina, PP; Waseem, TV, 2020) |
"Lactation ketoacidosis is an extremely rare type of high anion gap metabolic acidosis." | ( Al Alawi, AM; Al Amri, U; Falhammar, H, 2019) |
"Hyperketonemia is a metabolic disease in dairy cows, associated with negative nutrition balance (NNB) induced by low dry matter intake (DMI) and increased nutrient requirements." | ( Abdelatty, AM; Du, X; Li, G; Li, X; Liu, G; Mohamed, FF; Peng, Z; Sun, X; Wang, Z; Xu, Q; Zhao, C, 2020) |
"Ketosis is a metabolic disorder often triggered by anorexia in animals fed on high energy diets." | ( Bochmann, M; Clauss, M; Hatt, JM; Hetzel, U; Riond, B; Schmid, NS, 2020) |
"Ketosis is a metabolic disease of dairy cows often characterized by high concentrations of ketone bodies and fatty acids, but low milk protein and milk production." | ( Chen, X; Dong, J; Fang, Z; Guan, Y; Jia, H; Li, X; Liu, G; Loor, JJ; Shu, X; Wang, Y; Zuo, R, 2020) |
"Ketosis is a metabolic disorder of increasing importance in high-yielding dairy cows, but accurate population-wide binary health trait recording is difficult to implement." | ( Klein, SL; König, S; May, K; Scheper, C, 2020) |
"Ketosis is a serious metabolic disorder characterized by systemic and hepatic oxidative stress, inflammation, and apoptosis, as well as reduced milk yield." | ( Cao, Z; Jia, H; Jiang, C; Liang, Y; Loor, JJ; Luo, S; Shao, G; Sun, X; Tang, Y; Xu, C; Xu, Q; Zhao, C, 2021) |
"Clinical ketosis is common during the dairy cows' transition period and is responsible for considerable economic loss." | ( Bannert, E; Baumgartner, W; Kadáši, M; Kaiser, A; Klein, R; Köller, G; Leonhardt, AS; Pietsch, F; Rachidi, F; Schären, M; Snedec, T; Spilke, J; Starke, A; Theile, S; Theinert, K, 2021) |
"Ketosis is a common metabolic disorder in high-producing dairy cows during the peripartal period." | ( Du, X; Feng, X; Li, C; Li, N; Li, X; Liang, Y; Liu, G; Loor, JJ; Shu, X; Song, Y; Wang, Z; Yang, Y, 2021) |
"Ketosis is one of the most frequent metabolic diseases in high-yielding dairy cows and is characterized by high concentrations of ketone bodies in blood, urine, and milk, causing high economic losses." | ( Duffield, T; Schenkel, F; Soares, RAN; Squires, EJ; Vargas, G, 2021) |
"Starvation ketosis is usually a benign entity, however when combined with factors such as stress of critical illness, can produce metabolic acidosis which at times can be severe." | ( Barnett, R; Khanin, Y; Parikh, R; Sharma, P; Wanchoo, R, 2022) |
"Fasting ketoacidosis is especially an underdiagnosed problem in patients with neuro-muscular disease with severely depleted muscular mass." | ( Grady, BP; Kemming, JL; Koop, K; van Dam, M; Vissers, LATM, 2021) |
"Key Message: Ketoacidosis is a major feature of common clinical conditions to include diabetic ketoacidosis, alcoholic ketoacidosis, salicylate intoxication, SGLT2 inhibitor therapy, and calorie sufficient but carbohydrate-restricted diets." | ( Clegg, DJ; Palmer, BF, 2021) |
"Ketoacidosis is a potentially fatal complication that often presents as euglycaemic ketoacidosis during SGLT2 inhibitor treatment." | ( Iwasaki, Y; Karita, K; Kuratani, N; Seki, H; Shiga, T; Yasuda, K; Yorozu, T, 2021) |
"Ketoacidosis is relatively common and should be considered as a cause of sudden death, especially in alcoholic patients and patients with diabetes with no clear cause of death at autopsy." | ( Beresford, P; Davidson, F; Gallagher, PJ; Gwiti, P, 2023) |
"Lactation ketoacidosis is a very rare cause of metabolic acidosis in breastfeeding patients." | ( Oliver, JJ; Osborne, KC, 2022) |
"Ketosis is an alternative route for energy supply and provides the same metabolic effects as insulin but at the metabolic or primitive control level, which bypasses the complex signaling pathway of insulin." | ( Grande, G; Milardi, D; Zolla, L, 2022) |
"Ketosis is a common metabolic disorder in peripartal dairy cows that is caused by excessive mobilization of fat and incomplete hepatic metabolism of fatty acids (FFA)." | ( Fan, W; Gao, C; Jiang, Q; Li, M; Loor, JJ; Tian, Y; Wang, S; Xu, C; Yang, M; Yang, W; Zhang, B, 2022) |
"Ketosis is one of the most important health problems in dairy sheep." | ( Faillace, V; Fiore, E; Fiore, F; Harvatine, K; Laghi, L; Lisuzzo, A; Mazzotta, E; Moscati, L; Spissu, N; Zhu, C, 2022) |
"Ketosis is a metabolic disease of dairy cows in the perinatal period, β-hydroxybutyrate (β-HB) is the main component of ketosis." | ( Chen, M; Gao, X; Hong, H; Jiang, L; Jiang, Y; Jin, Q; Jin, Z; Liu, W; Qian, Y; Wei, Z; Xu, J; Yang, Z; Zhang, H; Zhang, X, 2023) |
"Ketosis is a metabolic disease of dairy cows in the perinatal period, β-hydroxybutyrate (β-HB) is the main component of ketosis." | ( Chen, M; Gao, X; Hong, H; Jiang, L; Jiang, Y; Jin, Q; Jin, Z; Liu, W; Qian, Y; Wei, Z; Xu, J; Yang, Z; Zhang, H; Zhang, X, 2023) |
"Ketosis is a common nutritional metabolic disease during the perinatal period in dairy cows." | ( Cao, J; Dai, D; Fang, L; Liu, H; Ning, M; Wang, B; Yao, C; Zhang, Y; Zhao, Y, 2023) |