diazoxide has been researched along with Acetonemia in 5 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "4 children with ketotic hypoglycemia (KH) showed during a fasting period over 24 hours significant higher decreases of serum alanine levels than normal controls." | 3.66 | [Pathogenesis of ketotic hypoglycemia (author's transl)]. ( Ploier, R; Sommer, R; Tulzer, W, 1979) |
| "Hyperosmolar coma with ketoacidosis is a rare side-effect of diazoxide therapy, documented even in patients with persistent hyperinsulinemic hypoglycemia of infancy." | 1.48 | Diazoxide toxicity in a child with persistent hyperinsulinemic hypoglycemia of infancy: mixed hyperglycemic hyperosmolar coma and ketoacidosis. ( Bhatia, V; Ellard, S; Flanagan, SE; Hussain, K; Mangla, P, 2018) |
| "Diazoxide is an agonist of the pancreatic beta-cell KATP channel and inhibits insulin secretion." | 1.33 | Ketotic hypoglycaemia in children with diazoxide responsive hyperinsulinism of infancy. ( Hussain, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mangla, P | 1 |
| Hussain, K | 2 |
| Ellard, S | 1 |
| Flanagan, SE | 1 |
| Bhatia, V | 1 |
| Panizon, F | 1 |
| Ventura, A | 1 |
| Ploier, R | 1 |
| Tulzer, W | 1 |
| Sommer, R | 1 |
| Némethová, V | 1 |
| Vigas, M | 1 |
| Lukác, J | 1 |
| Fatranská, M | 1 |
1 review available for diazoxide and Acetonemia
| Article | Year |
|---|---|
[Juvenile endocrine hypoglycemia].
Topics: Adenoma; Child, Preschool; Diazoxide; Folic Acid; Fructose-1,6-Diphosphatase Deficiency; Gluconeogen | 1979 |
4 other studies available for diazoxide and Acetonemia
| Article | Year |
|---|---|
Diazoxide toxicity in a child with persistent hyperinsulinemic hypoglycemia of infancy: mixed hyperglycemic hyperosmolar coma and ketoacidosis.
Topics: Antihypertensive Agents; Congenital Hyperinsulinism; Diazoxide; Humans; Hyperglycemic Hyperosmolar N | 2018 |
Ketotic hypoglycaemia in children with diazoxide responsive hyperinsulinism of infancy.
Topics: Congenital Hyperinsulinism; Diazoxide; Humans; Hypoglycemia; Infant, Newborn; Insulin Antagonists; K | 2005 |
[Pathogenesis of ketotic hypoglycemia (author's transl)].
Topics: Acidosis; Alanine; Child; Child, Preschool; Deoxyglucose; Diazoxide; Epinephrine; Fasting; Female; H | 1979 |
[A case of idiopathic ketotic hypoglycemia successfully treated with diazoxid. (author's transl)].
Topics: Acidosis; Child, Preschool; Diazoxide; Female; Humans; Hypoglycemia; Ketosis | 1977 |