pentylenetetrazole has been researched along with Acetonemia in 10 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Seizures were induced with one of Pentelyntetrazole (PTZ), 4-Aminopyridine (AP) and Strychnine (STR)." | 7.85 | Antiseizure Effects of Ketogenic Diet on Seizures Induced with Pentylenetetrazole, 4-Aminopyridine and Strychnine in Wistar Rats. ( Desalu, OO; Kolo, PM; Olarinoye, JK; Olatunji, LA; Sanya, EO; Soladoye, AO, 2017) |
| "The purpose of this study was to test the hypothesis that a ketogenic diet would increase the resistance of rats to pentylenetetrazole (PTZ)-induced seizures and to understand the relation of ketonemia to seizure resistance." | 7.70 | A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. ( Bough, KJ; Eagles, DA, 1999) |
| " Seizure threshold was tested by intravenous infusion of pentylenetetrazole (PTZ) whereas seizure severity was determined from measuring the hindlimb extension to flexion (E/F) ratio after seizures were evoked by maximal electroshock stimulation (MES)." | 7.70 | A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion. ( Bough, KJ; Eagles, DA; Matthews, PJ, 2000) |
| " Seizures were induced with one of Pentelyntetrazole (PTZ), 4-Aminopyridine (AP) and Strychnine (STR)." | 3.85 | Antiseizure Effects of Ketogenic Diet on Seizures Induced with Pentylenetetrazole, 4-Aminopyridine and Strychnine in Wistar Rats. ( Desalu, OO; Kolo, PM; Olarinoye, JK; Olatunji, LA; Sanya, EO; Soladoye, AO, 2017) |
| "The purpose of this study was to test the hypothesis that a ketogenic diet would increase the resistance of rats to pentylenetetrazole (PTZ)-induced seizures and to understand the relation of ketonemia to seizure resistance." | 3.70 | A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. ( Bough, KJ; Eagles, DA, 1999) |
| "The present study was designed to evaluate the effects of age on the efficacy of the ketogenic diet in suppressing seizures evoked by tail-vein infusion of pentylenetetrazole (PTZ)." | 3.70 | Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet. ( Bough, KJ; Eagles, DA; Han, FT; Valiyil, R, 1999) |
| " Results also showed that the animals fed calorie-restricted high-fat diets exhibited significant ketonemia and protection from pentylenetetrazole (PTZ)-induced seizures." | 3.70 | Higher ketogenic diet ratios confer protection from seizures without neurotoxicity. ( Bough, KJ; Eagles, DA; Yao, SG, 2000) |
| " Seizure threshold was tested by intravenous infusion of pentylenetetrazole (PTZ) whereas seizure severity was determined from measuring the hindlimb extension to flexion (E/F) ratio after seizures were evoked by maximal electroshock stimulation (MES)." | 3.70 | A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion. ( Bough, KJ; Eagles, DA; Matthews, PJ, 2000) |
| "All subjects were seizure tested by using the PTZ infusion test." | 1.33 | A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats. ( Abdelmalik, PA; Burnham, WM; Clarke, J; Likhodii, S; Nylen, K, 2005) |
| "Results indicate that seizure threshold was significantly elevated with increasing ketogenic ratios (i." | 1.30 | Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat. ( Bough, KJ; Chen, RS; Eagles, DA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanya, EO | 1 |
| Soladoye, AO | 1 |
| Desalu, OO | 1 |
| Kolo, PM | 1 |
| Olatunji, LA | 1 |
| Olarinoye, JK | 1 |
| Nylen, K | 1 |
| Likhodii, S | 2 |
| Abdelmalik, PA | 1 |
| Clarke, J | 1 |
| Burnham, WM | 1 |
| Auvin, S | 1 |
| Shin, D | 1 |
| Mazarati, A | 1 |
| Sankar, R | 1 |
| Raffo, E | 1 |
| François, J | 1 |
| Ferrandon, A | 1 |
| Koning, E | 1 |
| Nehlig, A | 1 |
| Bough, KJ | 5 |
| Eagles, DA | 5 |
| Valiyil, R | 1 |
| Han, FT | 1 |
| Chen, RS | 1 |
| Yao, SG | 1 |
| Matthews, PJ | 1 |
10 other studies available for pentylenetetrazole and Acetonemia
| Article | Year |
|---|---|
Antiseizure Effects of Ketogenic Diet on Seizures Induced with Pentylenetetrazole, 4-Aminopyridine and Strychnine in Wistar Rats.
Topics: 4-Aminopyridine; Animal Nutritional Physiological Phenomena; Animals; Biomarkers; Blood Glucose; Die | 2017 |
A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats.
Topics: 3-Hydroxybutyric Acid; Age Factors; Animals; Blood Glucose; Body Weight; Dietary Fats; Disease Model | 2005 |
The utility of testing pentylenetetrazol threshold.
Topics: Age Factors; Animals; Body Weight; Brain; Convulsants; Diet Therapy; Disease Models, Animal; Epileps | 2006 |
Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Caloric Restriction; Cerebral Cortex; Di | 2008 |
A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat.
Topics: 3-Hydroxybutyric Acid; Animals; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Epileps | 1999 |
Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Behavior, Animal; Convulsants; Diet; Energy Intake; Growth; K | 1999 |
Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Body Weight; Convulsants; Diet; Differential Threshold; Disea | 1999 |
Higher ketogenic diet ratios confer protection from seizures without neurotoxicity.
Topics: 3-Hydroxybutyric Acid; Animals; Basal Metabolism; Behavior, Animal; Convulsants; Diet; Dietary Fats; | 2000 |
A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion.
Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Convulsants; Diet, Reducing; Dietary Fats; Electroshock; | 2000 |
Experiments in the rat pentylenetetrazole infusion threshold model of the ketogenic diet.
Topics: Age Factors; Animals; Convulsants; Dietary Carbohydrates; Dietary Proteins; Disease Models, Animal; | 2001 |