Compounds > isomaltitol
Page last updated: 2024-12-07

isomaltitol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Isomaltitol is a sugar alcohol produced by the hydrogenation of isomaltose, a disaccharide composed of glucose and fructose. It is approximately 60% as sweet as sucrose but contains less than half the calories. Isomaltitol is commonly used as a sugar substitute in food products due to its low glycemic index and its ability to provide a pleasant mouthfeel. It is also known to have a low cariogenic potential, meaning it does not contribute to tooth decay. Research on isomaltitol focuses on its potential applications in food science, its impact on gut health, and its potential as a prebiotic ingredient. '

6-O-alpha-D-glucopyranosyl-D-glucitol : A glycosyl alditol consisting of alpha-D-glucopyranose and D-glucitol residues joined in sequence by a (1->6)-glycosidic bond. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID94169
CHEBI ID152898
SCHEMBL ID371449
MeSH IDM0051824

Synonyms (28)

Synonym
isomaltitol
534-73-6
isomaltitol, >=98% (hplc)
alpha-d-glcp-(1->6)-d-glucitol
6-o-alpha-d-glucopyranosyl-d-glucitol
CHEBI:152898
alpha-d-glcp-(1->6)-d-glc-oh
(2s,3r,4r,5r)-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,4,5-pentol
einecs 208-605-3
d-glucitol, 6-o-alpha-d-glucopyranosyl-
unii-qfa026jzx2
qfa026jzx2 ,
d-glucitol, 6-o-.alpha.-d-glucopyranosyl-
glucosylsorbitol [mi]
6-o-.alpha.-d-glucopyranosyl-d-glucitol
6-o-.alpha.-glucopyranosyl-d-sorbitol
AKOS025311412
6-o-alpha-d-glucopyranosyl-d-sorbitol
SERLAGPUMNYUCK-YJOKQAJESA-N
SCHEMBL371449
DTXSID3074571
D81759
(2s,3r,4r,5r)-6-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol
(2s,3r,4r,5r)-6-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yloxy)hexane-1,2,3,4,5-pentaol
CS-0077793
Q27287232
HY-W032970
6-o--d-glucopyranosyl-d-glucitol

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"For the sake of metabolic insight into the fate of the sugar substitute Palatinit, its two components D-glucosyl-alpha (1 leads to 1)-D-mannitol and D-glucosyl-alpha (1 leads to 6)-D-glucitol [D-glucosyl-alpha-(1 leads to 6)-D-sorbitol] were assayed for glucose bioavailability by the procedure of Karimzadegan et al."( Bioavailability of glucose from Palatinit.
Ziesenitz, SC, 1983)		0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (1 Product(s))

Product Categories

Product CategoryProducts
Other1

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved

Drug Classes (2)

ClassDescription
O-acyl carbohydrateA carbohydrate derivative in which the hydrogen atom of at least one alcoholic hydroxy group of a carbohydrate has been replaced by an acyl substituent.
glycosyl alditol
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 42.49

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index42.49 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index59.54 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (42.49)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
sorbitol
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).		1.9610glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
lysine
Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine.		2.1510aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
sucrose
Saccharum: A plant genus of the family POACEAE widely cultivated in the tropics for the sweet cane that is processed into sugar.		1.9710glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
mannitol
[no description available]		1.9610mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
isomaltose
[no description available]		2.1510
d-glucitol, 6-o-alpha-d-glucopyranosyl-, mixture with 1-o-alpha-d-glucopyranosyl-d-mannitol
Palatinit: mixture of 1,6-mannitol glucopyranoside & 1,6-sorbitol glucopyranoside that affects de- and remineralization; non-cariogenic. 1-O-alpha-D-glucopyranosyl-D-mannitol : A 1-O-D-glucopyranosyl-D-mannitol that has alpha configuration at the anomeric centre.		2.3720(2xi)-6-O-alpha-D-glucopyranosyl-D-arabino-hexitol;
1-O-D-glucopyranosyl-D-mannitol
panose
panose : A trisaccharide composed of D-glucopyranose units.		2.1510trisaccharideplant metabolite
lactitol
lactitol : A glycosyl alditol consisting of beta-D-galactopyranose and D-glucitol joined by a 1->4 glycosidic bond. It is used as a laxative, as an excipient, and as replacement bulk sweetener in some low-calorie foods.		710glycosyl alditolcathartic;
excipient;
laxative
maltitol
maltitol : An alpha-D-glucoside consisting of D-glucitol having an alpha-D-glucosyl residue attached at the 4-position. Used as a sugar substitute.		710alpha-D-glucoside;
glycosyl alditol		laxative;
metabolite;
sweetening agent
acebutolol
alpha-D-glucosyl-(1->4)-alpha-D-mannose : An alpha-D-glucosyl-(1->4)-D-mannopyranose in which the anomeric hydroxy group has alpha configuration.		2.4420alpha-D-glucosyl-(1->4)-D-mannopyranose
ConditionIndicatedRelationship StrengthStudiesTrials
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.0610
Eosinophilia, Tropical
[description not available]		02.0610
Experimental Lung Inflammation
Inflammation of any part, segment or lobe, of the lung parenchyma.		02.0610
Eosinophilia
Abnormal increase of EOSINOPHILS in the blood, tissues or organs.		07.0610
Pneumonia
Infection of the lung often accompanied by inflammation.		02.0610
Metabolic Acidosis
[description not available]		01.9610
Acetonemia
[description not available]		01.9610
Acidosis
A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.		01.9610
Experimental Neoplasms
[description not available]		01.9710