valproic acid has been researched along with Acetonemia in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was performed to evaluate carnitine deficiency in a large series of epilepsy children and adolescents treated with old and new antiepileptic drugs with or without ketogenic diet." | 9.12 | Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet. ( Auricchio, G; Coppola, G; Epifanio, G; Federico, RR; Pascotto, A; Resicato, G, 2006) |
| "We observed two patients who developed coma following administration of valproate in dosages of 32 to 40 mg/kg per day." | 5.28 | Valproate-induced coma with ketosis and carnitine insufficiency. ( Bohan, TP; Lin, SN; Triggs, WJ; Willmore, LJ, 1990) |
| "This study was performed to evaluate carnitine deficiency in a large series of epilepsy children and adolescents treated with old and new antiepileptic drugs with or without ketogenic diet." | 5.12 | Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet. ( Auricchio, G; Coppola, G; Epifanio, G; Federico, RR; Pascotto, A; Resicato, G, 2006) |
| " Adverse events and reasons for terminating the diet were tabulated." | 1.33 | Safety and tolerability of the ketogenic diet in pediatric epilepsy: effects of valproate combination therapy. ( Ghosh, S; Lyczkowski, DA; Pfeifer, HH; Thiele, EA, 2005) |
| "We observed two patients who developed coma following administration of valproate in dosages of 32 to 40 mg/kg per day." | 1.28 | Valproate-induced coma with ketosis and carnitine insufficiency. ( Bohan, TP; Lin, SN; Triggs, WJ; Willmore, LJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spilioti, M | 1 |
| Pavlou, E | 1 |
| Gogou, M | 1 |
| Katsanika, I | 1 |
| Papadopoulou-Alataki, E | 1 |
| Grafakou, O | 1 |
| Gkampeta, A | 1 |
| Dinopoulos, A | 1 |
| Evangeliou, A | 1 |
| Junig, JT | 1 |
| Lehrmann, JA | 1 |
| Lyczkowski, DA | 1 |
| Pfeifer, HH | 1 |
| Ghosh, S | 1 |
| Thiele, EA | 1 |
| Coppola, G | 1 |
| Epifanio, G | 1 |
| Auricchio, G | 1 |
| Federico, RR | 1 |
| Resicato, G | 1 |
| Pascotto, A | 1 |
| Mortensen, PB | 1 |
| Ballaban-Gil, K | 1 |
| Callahan, C | 1 |
| O'Dell, C | 1 |
| Pappo, M | 1 |
| Moshé, S | 1 |
| Shinnar, S | 1 |
| Triggs, WJ | 1 |
| Bohan, TP | 1 |
| Lin, SN | 1 |
| Willmore, LJ | 1 |
1 review available for valproic acid and Acetonemia
| Article | Year |
|---|---|
Dicarboxylic acids and the lipid metabolism.
Topics: Acyl Coenzyme A; Animals; Carboxylic Acids; Carnitine O-Acetyltransferase; Coenzyme A; Dicarboxylic | 1984 |
2 trials available for valproic acid and Acetonemia
| Article | Year |
|---|---|
Valproate effect on ketosis in children under ketogenic diet.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Combined Modality Therapy; Diet, Ketogenic; Ep | 2016 |
Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Carnitine; Child; Child, Preschool; Dietary Fats; | 2006 |
4 other studies available for valproic acid and Acetonemia
| Article | Year |
|---|---|
A psychotic episode associated with the Atkins diet in a patient with bipolar disorder.
Topics: Antimanic Agents; Anxiety; Bipolar Disorder; Confusion; Diet Fads; Humans; Ketosis; Male; Middle Age | 2005 |
Safety and tolerability of the ketogenic diet in pediatric epilepsy: effects of valproate combination therapy.
Topics: Acidosis; Anticonvulsants; Child; Child, Preschool; Combined Modality Therapy; Dietary Fats; Epileps | 2005 |
Complications of the ketogenic diet.
Topics: Adolescent; Carnitine; Child; Child, Preschool; Combined Modality Therapy; Epilepsy; Follow-Up Studi | 1998 |
Valproate-induced coma with ketosis and carnitine insufficiency.
Topics: Acids; Adult; Carnitine; Coma; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Ketosis | 1990 |