Page last updated: 2024-10-16

acetone and Acetonemia

acetone has been researched along with Acetonemia in 75 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Research Excerpts

ExcerptRelevanceReference
"Ketosis is also produced during fasting periods, which is known as fasting ketosis (FK)."6.80Acetone as biomarker for ketosis buildup capability--a study in healthy individuals under combined high fat and starvation diets. ( Forzani, ES; Jackemeyer, D; Prabhakar, A; Quach, A; Tao, N; Terrera, M; Tsow, F; Xian, X; Zhang, H, 2015)
"In diabetes mellitus (DM) patients with ketoacidosis, ketone bodies, i."5.40Determination of acetone in saliva by reversed-phase liquid chromatography with fluorescence detection and the monitoring of diabetes mellitus patients with ketoacidosis. ( Fujii, S; Inoue, K; Kitagawa, Y; Maeda, T; Min, JZ; Noge, I; Todoroki, K; Toyo'oka, T, 2014)
"Acetone is considered to be a substance that can disturb cellular oxidative status, being also associated with the production of glucose during its metabolization."5.36Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH? ( de Almeida, BB; Jordao, AA; Mathias, MG; Portari, GV, 2010)
"Although ketosis is an integral aspect of these therapeutic regimens, the direct importance of ketosis to seizure control needs further investigation."5.31Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone. ( Comeau, F; Cunnane, S; Curtis, R; Musa-Veloso, K; Rarama, E, 2002)
"Data from 191 post-mortem cases where post-mortem blood beta-hydroxybutyrate (βHB) and acetone concentrations and vitreous humor glucose concentrations (where available) had been measured were retrospectively investigated to determine the markers required to identify and distinguish between Alcoholic Ketoacidosis (AKA), Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycemic State (HHS)."3.78Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples. ( Andrews, R; Dhillo, W; Hockenhull, J; Paterson, S, 2012)
" In a first series, acetone was determined in the blood of such chronic alcoholics (n = 24), diabetics with metabolic decompensation (n = 7), cases of hypothermia (n = 7) and controls (n = 218)."3.70Ketoacidosis and lactic acidosis--frequent causes of death in chronic alcoholics? ( Brinkmann, B; DuChesne, A; Fechner, G; Karger, B, 1998)
"Erythrocytes were washed, suspended in buffers containing 5 mM glucose (simulates euglycemia) or 25 mM glucose (simulates hyperglycemia), and incubated with acetone (5 and 10 mM, acetoacetate (5 and 10 mM), or beta-hydroxybutyrate (5 and 25 mM) for 24 hours at 37 C."3.69In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production. ( Christopher, MM; Fallin, CW, 1996)
"Ketosis is also produced during fasting periods, which is known as fasting ketosis (FK)."2.80Acetone as biomarker for ketosis buildup capability--a study in healthy individuals under combined high fat and starvation diets. ( Forzani, ES; Jackemeyer, D; Prabhakar, A; Quach, A; Tao, N; Terrera, M; Tsow, F; Xian, X; Zhang, H, 2015)
"Ketosis is believed to be necessary to the anticonvulsant mechanism of the ketogenic diet; however, the relationship between ketosis and seizure control has not been established."2.42Non-invasive detection of ketosis and its application in refractory epilepsy. ( Musa-Veloso, K, 2004)
"Ketosis is normal during fasting, after prolonged exercise, and when a high-fat diet is consumed."2.39Medical aspects of ketone body metabolism. ( Ashmarina, L; Boukaftane, Y; Kassovska-Bratinova, S; Lambert, M; Lapierre, P; Mitchell, GA; Potier, E; Robert, MF; Wang, SP, 1995)
"Most patients with diabetic ketoacidosis will respond to low-dose, hourly, intravenous or intramuscular regular insulin."2.36Diabetic ketoacidosis: new concepts and trends in pathogenesis and treatment. ( Kreisberg, RA, 1978)
"Subclinical metabolic disorders such as ketosis cause substantial economic losses for dairy farmers in addition to the serious welfare issues they pose for dairy cows."1.56Predictive ability of host genetics and rumen microbiome for subclinical ketosis. ( Buitenhuis, B; Difford, GF; Gebreyesus, G; Højberg, O; Lassen, J; Løvendahl, P; Noel, SJ; Plichta, DR; Poulsen, NA; Sahana, G; Sundekilde, UK; Zhu, Z, 2020)
"Subclinical (SCK) and clinical (CK) ketosis are metabolic disorders responsible for big losses in dairy production."1.56Opportunities and limitations of milk mid-infrared spectra-based estimation of acetone and β-hydroxybutyrate for the prediction of metabolic stress and ketosis in dairy cows. ( Bruckmaier, RM; Caldeira, MO; Dan, D; Glauser, DL; Gross, JJ; Moll, J; Neuheuser, AL; Schuler, U; Stierli, M; Stürmlin, R; Weber, C; Wegmann, S, 2020)
"Positive BHB is proof of endogenous ketoacidosis, whereas negative BHB indicates isopropanol intoxication or postmortem acetone/isopropanol formation by microorganisms in cases of decomposition."1.56Postmortem diagnosis of ketoacidosis: Levels of beta-hydroxybutyrate, acetone and isopropanol in different causes of death. ( Eriksson Hydara, Y; Zilg, B, 2020)
"Ketosis is a metabolic disorder of increasing importance in high-yielding dairy cows, but accurate population-wide binary health trait recording is difficult to implement."1.56Genetic and nongenetic profiling of milk β-hydroxybutyrate and acetone and their associations with ketosis in Holstein cows. ( Klein, SL; König, S; May, K; Scheper, C, 2020)
"Ketosis is a metabolic disorder often triggered by anorexia in animals fed on high energy diets."1.56Development, diagnosis and therapy of ketosis in non-gravid and non-lactating Guinea pigs. ( Bochmann, M; Clauss, M; Hatt, JM; Hetzel, U; Riond, B; Schmid, NS, 2020)
"Fetal ketoacidosis with hypoxic-ischemic brain damage was determined to be the cause of death."1.48Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis. ( Fliss, B; Gascho, D; Heimer, J; Martinez, RM; Zoelch, N, 2018)
"Therein, the level of ketosis must be regulated tightly to ensure an effective therapy."1.48Guiding Ketogenic Diet with Breath Acetone Sensors. ( Geidl, B; Gerber, PA; Güntner, AT; Kohler, M; Kompalla, JF; Landis, H; Pratsinis, SE; Sievi, NA; Theodore, SJ, 2018)
"Starvation ketoacidosis is a rare cause of metabolic acidosis and is a phenomenon that occurs normally during fasting, as the body switches from carbohydrate to lipid energy sources."1.43Postmortem biochemistry in suspected starvation-induced ketoacidosis. ( Augsburger, M; Burkhardt, S; Lardi, C; Palmiere, C; Sabatasso, S; Tettamanti, C; Werner, D, 2016)
"To manage negative energy balance and ketosis in dairy farms, rapid and cost-effective detection is needed."1.43Development of Fourier transform mid-infrared calibrations to predict acetone, β-hydroxybutyrate, and citrate contents in bovine milk through a European dairy network. ( Bastin, C; Colinet, FG; Dardenne, P; Davière, JB; Dehareng, F; Fernandez Pierna, JA; Gelé, M; Gengler, N; Grelet, C; Johan, M; Reding, R; Soyeurt, H; Werner, A, 2016)
"The model predicted clinical ketosis with a sensitivity of 100% and a specificity of 100%."1.40(1)H-Nuclear magnetic resonance-based plasma metabolic profiling of dairy cows with clinical and subclinical ketosis. ( Shu, S; Sun, LW; Wu, L; Xia, C; Xu, C; Zhang, HY; Zheng, JS, 2014)
"In diabetes mellitus (DM) patients with ketoacidosis, ketone bodies, i."1.40Determination of acetone in saliva by reversed-phase liquid chromatography with fluorescence detection and the monitoring of diabetes mellitus patients with ketoacidosis. ( Fujii, S; Inoue, K; Kitagawa, Y; Maeda, T; Min, JZ; Noge, I; Todoroki, K; Toyo'oka, T, 2014)
"Hyperketonemia was defined by a blood BHBA concentration ≥ 1."1.40Accuracy of milk ketone bodies from flow-injection analysis for the diagnosis of hyperketonemia in dairy cows. ( Denis-Robichaud, J; DesCôteaux, L; Dubuc, J; Lefebvre, D, 2014)
"Alcohol ketoacidosis is a frequently missed diagnosis, but is well described in the literature."1.39Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient. ( Dwyer, JB; Tamama, K, 2013)
"However, in ketosis, acetone can be reduced to IPA."1.38Blood, urine and vitreous isopropyl alcohol as biochemical markers in forensic investigations. ( Augsburger, M; Bardy, D; Mangin, P; Palmiere, C; Sporkert, F; Werner, D, 2012)
" The diagnostic model is, in our opinion, valuable for herd-level monitoring of hyperketonemia, especially when the model is combined with wet chemistry analysis of milk acetone or milk BHBA concentrations."1.38Routine detection of hyperketonemia in dairy cows using Fourier transform infrared spectroscopy analysis of β-hydroxybutyrate and acetone in milk in combination with test-day information. ( Jorritsma, R; Knijn, HM; Schonewille, JT; Stegeman, JA; van der Drift, SGA, 2012)
"Acetone was about 16-fold higher with LC-75/10 only (P < 0."1.37Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. ( Bidlingmaier, M; Bielohuby, M; Christ, B; Hempel, M; Kienzle, E; Kirchner, H; Menhofer, D; Müller, TD; Pfluger, PT; Stemmer, K; Stock, P; Stoehr, BJ; Tschöp, MH, 2011)
"Acetone is considered to be a substance that can disturb cellular oxidative status, being also associated with the production of glucose during its metabolization."1.36Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH? ( de Almeida, BB; Jordao, AA; Mathias, MG; Portari, GV, 2010)
"Diabetic patients frequently encounter ketosis that is characterized by the breakdown of lipids with the consequent accumulation of ketone bodies."1.35Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis. ( Bonini, MG; Dallas, S; Duma, D; Kadiiska, MB; Mason, RP; Stadler, K, 2008)
"Subclinical ketosis is a metabolic disorder in high-producing dairy cattle that can be detected by ketone bodies in milk: acetone (Ac), acetoacetate (AcAc), and beta-hydroxybutyrate (BHBA)."1.34Screening for subclinical ketosis in dairy cattle by Fourier transform infrared spectrometry. ( de Jong, G; de Roos, AP; Hørlyk, J; van den Bijgaart, HJ, 2007)
"Acetone has been shown to have broad-spectrum anticonvulsant actions in animal seizure models and has been hypothesized to play a role in the anticonvulsant mechanism of the ketogenic diet (KD)."1.33A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats. ( Burnham, WM; Hum, KM; Likhodii, SS; Nylen, K, 2006)
"Aminoacetone (AA) is a threonine and glycine metabolite overproduced and recently implicated as a contributing source of methylglyoxal (MG) in conditions of ketosis."1.32Aminoacetone induces loss of ferritin ferroxidase and iron uptake activities. ( Araki, D; Bechara, EJ; Dutra, F, 2003)
"Although ketosis is an integral aspect of these therapeutic regimens, the direct importance of ketosis to seizure control needs further investigation."1.31Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone. ( Comeau, F; Cunnane, S; Curtis, R; Musa-Veloso, K; Rarama, E, 2002)
"For the detection of subclinical ketosis, the best sensitivity-specificity combination was obtained with the determination of acetoacetate in blood or milk, with threshold concentrations of 125 and 50 micromol/L, respectively."1.31Ketone bodies in milk and blood of dairy cows: relationship between concentrations and utilization for detection of subclinical ketosis. ( Bayourthe, C; Enjalbert, F; Moncoulon, R; Nicot, MC, 2001)
"To understand how ketosis and seizure protection are related, a reliable, noninvasive measure of ketosis that can be performed frequently with minimal discomfort is needed."1.31Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals. ( Cunnane, SC; Likhodii, SS; Musa-Veloso, K, 2002)
"Thus the stage of lactation and of ketosis should be taken into consideration when the correlation between milk parameters and milk production is evaluated."1.29Relationship between milk acetone and milk yield in individual cows. ( Miettinen, PV, 1994)
"Forensic pathologists are familiar with alcohol abusers, who are found dead and in whom the cause of death cannot be ascertained."1.29Alcoholic ketoacidosis as a cause of death in forensic cases. ( Felby, S; Nielsen, E; Theilade, P; Thomsen, JL, 1995)
"The significance of ketosis in this syndrome has been evaluated from several viewpoints."1.27Can marked hyperglycemia occur without ketosis? ( Halperin, ML; Marsden, PA; Singer, GG; West, ML, 1985)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199020 (26.67)18.7374
1990's11 (14.67)18.2507
2000's15 (20.00)29.6817
2010's21 (28.00)24.3611
2020's8 (10.67)2.80

Authors

AuthorsStudies
Schmid, NS1
Clauss, M1
Hetzel, U1
Riond, B1
Bochmann, M1
Hatt, JM1
Gebreyesus, G1
Difford, GF1
Buitenhuis, B1
Lassen, J1
Noel, SJ1
Højberg, O1
Plichta, DR1
Zhu, Z1
Poulsen, NA1
Sundekilde, UK1
Løvendahl, P1
Sahana, G1
Caldeira, MO1
Dan, D1
Neuheuser, AL1
Stürmlin, R1
Weber, C1
Glauser, DL1
Stierli, M1
Schuler, U1
Moll, J1
Wegmann, S1
Bruckmaier, RM1
Gross, JJ1
Eriksson Hydara, Y1
Zilg, B1
Klein, SL1
Scheper, C1
May, K1
König, S1
Wang, D1
Zhang, F1
Prabhakar, A2
Qin, X1
Forzani, ES2
Tao, N2
Alkedeh, O1
Priefer, R1
Yang, F1
Yang, L2
Xu, L1
Guo, W1
Pan, L1
Zhang, C1
Xu, S1
Zhang, N1
Jiang, C1
Chandler, TL1
Pralle, RS1
Dórea, JRR1
Poock, SE1
Oetzel, GR1
Fourdraine, RH1
White, HM1
Heimer, J1
Gascho, D1
Fliss, B1
Martinez, RM1
Zoelch, N1
Güntner, AT1
Kompalla, JF1
Landis, H1
Theodore, SJ1
Geidl, B1
Sievi, NA1
Kohler, M1
Pratsinis, SE1
Gerber, PA1
Ho, CF1
Chan, KW1
Yeh, HI1
Kuo, J1
Liu, HJ1
Wang, CY1
Sun, LW1
Zhang, HY1
Wu, L1
Shu, S1
Xia, C1
Xu, C1
Zheng, JS1
Fujii, S1
Maeda, T1
Noge, I1
Kitagawa, Y1
Todoroki, K1
Inoue, K1
Min, JZ1
Toyo'oka, T1
Denis-Robichaud, J1
Dubuc, J1
Lefebvre, D1
DesCôteaux, L1
Reyes-Reyes, A1
Horsten, RC1
Urbach, HP1
Bhattacharya, N1
Quach, A1
Zhang, H1
Terrera, M1
Jackemeyer, D1
Xian, X1
Tsow, F1
Grelet, C1
Bastin, C1
Gelé, M1
Davière, JB1
Johan, M1
Werner, A1
Reding, R1
Fernandez Pierna, JA1
Colinet, FG1
Dardenne, P1
Gengler, N1
Soyeurt, H1
Dehareng, F1
Palmiere, C2
Tettamanti, C1
Augsburger, M2
Burkhardt, S1
Sabatasso, S1
Lardi, C1
Werner, D2
Sadones, N1
Lambert, WE1
Stove, CP1
Stadler, K1
Bonini, MG1
Dallas, S1
Duma, D1
Mason, RP1
Kadiiska, MB1
Freemantle, E1
Vandal, M1
Tremblay Mercier, J1
Plourde, M1
Poirier, J1
Cunnane, SC3
de Almeida, BB1
Mathias, MG1
Portari, GV1
Jordao, AA1
Sato, H1
Prevost, M1
Sun, Y1
Servilla, KS1
Massie, L1
Glew, RH1
Tzamaloukas, AH1
Bielohuby, M1
Menhofer, D1
Kirchner, H1
Stoehr, BJ1
Müller, TD1
Stock, P1
Hempel, M1
Stemmer, K1
Pfluger, PT1
Kienzle, E1
Christ, B1
Tschöp, MH1
Bidlingmaier, M1
Hockenhull, J1
Dhillo, W1
Andrews, R1
Paterson, S1
Sporkert, F1
Bardy, D1
Mangin, P1
Petersen, TH1
Williams, T1
Nuwayhid, N1
Harruff, R1
van der Drift, SGA1
Jorritsma, R2
Schonewille, JT1
Knijn, HM1
Stegeman, JA1
van der Drift, SG1
van Hulzen, KJ1
Teweldemedhn, TG1
Nielen, M1
Heuven, HC1
Dwyer, JB1
Tamama, K1
Musa-Veloso, K3
Rarama, E1
Comeau, F1
Curtis, R1
Cunnane, S1
Reist, M1
Erdin, DK1
von Euw, D1
Tschümperlin, KM1
Leuenberger, H1
Hammon, HM1
Künzi, N1
Blum, JW1
SCHOLZ, H1
SERRADELL CAPDEVILA, J1
ROYER, P1
HILLER, J1
SAVEL, LE1
LILIEN, R1
SIMON, SR1
HANSEN, E1
SUZUKI, M1
KAWAKATSU, T1
KAMOSHITA, S1
KAWAGUCHI, H1
SUZUKI, Y1
MATOUSEK, M1
Dutra, F1
Araki, D1
Bechara, EJ1
CARLSTROM, B1
ROBERTS, SJ1
DYE, JA1
ALLIMANT, H1
PEIFFERT, G1
PUNTRIANO, G1
LESTRADET, H1
GUEST, GM1
Nylen, K1
Likhodii, SS3
Hum, KM1
Burnham, WM1
de Roos, AP1
van den Bijgaart, HJ1
Hørlyk, J1
de Jong, G1
Gasior, M1
Hartman, AL1
Rogawski, MA1
Van der Walt, JG1
Hunter, G1
Procos, J1
Kupari, M1
Lommi, J1
Ventilä, M1
Karjalainen, U1
Mitchell, GA1
Kassovska-Bratinova, S1
Boukaftane, Y1
Robert, MF1
Wang, SP1
Ashmarina, L1
Lambert, M1
Lapierre, P1
Potier, E1
Miettinen, PV1
Thomsen, JL1
Felby, S1
Theilade, P1
Nielsen, E1
Steen, A2
Osterås, O2
Grønstøl, H2
Fallin, CW1
Christopher, MM1
Dobbelaar, P1
Mottram, T1
Nyabadza, C1
Hobbs, P1
Elliott-Martin, RJ1
Schukken, YH2
Brinkmann, B1
Fechner, G1
Karger, B1
DuChesne, A1
Pounder, DJ1
Stevenson, RJ1
Taylor, KK1
Hansen, PW1
Heuer, C1
Luinge, HJ1
Lutz, ET1
van der Maas, JH1
Wilmink, H1
Noordhuizen, JP1
Enjalbert, F1
Nicot, MC1
Bayourthe, C1
Moncoulon, R1
Cook, NB1
Ward, WR1
Dobson, H1
Musa, K1
Kreisberg, RA1
Vojtísek, B1
Hamrík, J1
Hronová, B1
Diblíková, I1
Minksová, E1
Gajdosík, D1
Neiman, J1
Jones, AW1
Numminen, H1
Hillbom, M1
Halperin, ML1
Marsden, PA1
Singer, GG1
West, ML1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Characterization of a Portable Solid-State Breath Acetone Testing Device for Real-Time Ketosis Status and Comparison to Blood Ketone Testing[NCT04130724]21 participants (Actual)Observational2019-10-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for acetone and Acetonemia

ArticleYear
The Ketogenic Diet: Breath Acetone Sensing Technology.
    Biosensors, 2021, Jan-19, Volume: 11, Issue:1

    Topics: Acetone; Biosensing Techniques; Breath Tests; Diet, Ketogenic; Humans; Ketosis; Weight Reduction Pro

2021
Non-invasive detection of ketosis and its application in refractory epilepsy.
    Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 70, Issue:3

    Topics: Acetone; Animals; Epilepsy; Humans; Ketones; Ketosis; Seizures

2004
Medical aspects of ketone body metabolism.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1995, Volume: 18, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Biological Evolution; Brain; Humans; Hydroxybutyrates

1995
Diabetic ketoacidosis: new concepts and trends in pathogenesis and treatment.
    Annals of internal medicine, 1978, Volume: 88, Issue:5

    Topics: Acetoacetates; Acetone; Animals; Central Nervous System; Diabetes Mellitus; Diabetic Ketoacidosis; D

1978

Trials

2 trials available for acetone and Acetonemia

ArticleYear
Acetone as biomarker for ketosis buildup capability--a study in healthy individuals under combined high fat and starvation diets.
    Nutrition journal, 2015, Apr-22, Volume: 14

    Topics: Acetone; Adult; Biomarkers; Blood Glucose; Breath Tests; Cross-Over Studies; Diet, Carbohydrate-Rest

2015
Metabolic response to a ketogenic breakfast in the healthy elderly.
    The journal of nutrition, health & aging, 2009, Volume: 13, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Apolipoprotein E4

2009

Other Studies

69 other studies available for acetone and Acetonemia

ArticleYear
Development, diagnosis and therapy of ketosis in non-gravid and non-lactating Guinea pigs.
    BMC veterinary research, 2020, Feb-03, Volume: 16, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animal Nutritional Physiological Phenomena; Animals;

2020
Predictive ability of host genetics and rumen microbiome for subclinical ketosis.
    Journal of dairy science, 2020, Volume: 103, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Female; Gastrointestinal Microbiom

2020
Opportunities and limitations of milk mid-infrared spectra-based estimation of acetone and β-hydroxybutyrate for the prediction of metabolic stress and ketosis in dairy cows.
    The Journal of dairy research, 2020, Volume: 87, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Female; Ketosis; Lactation; Milk;

2020
Postmortem diagnosis of ketoacidosis: Levels of beta-hydroxybutyrate, acetone and isopropanol in different causes of death.
    Forensic science international, 2020, Volume: 314

    Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drin

2020
Genetic and nongenetic profiling of milk β-hydroxybutyrate and acetone and their associations with ketosis in Holstein cows.
    Journal of dairy science, 2020, Volume: 103, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Female; Genome-Wide Association St

2020
Colorimetric Sensor for Online Accurate Detection of Breath Acetone.
    ACS sensors, 2021, 02-26, Volume: 6, Issue:2

    Topics: Acetone; Breath Tests; Colorimetry; Diabetes Mellitus; Humans; Ketosis

2021
3D-printed smartphone-based device for fluorimetric diagnosis of ketosis by acetone-responsive dye marker and red emissive carbon dots.
    Mikrochimica acta, 2021, Aug-27, Volume: 188, Issue:9

    Topics: Acetone; Biomarkers; Breath Tests; Carbon; Exhalation; Humans; Hydrazines; Ketosis; Limit of Detecti

2021
Predicting hyperketonemia by logistic and linear regression using test-day milk and performance variables in early-lactation Holstein and Jersey cows.
    Journal of dairy science, 2018, Volume: 101, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Dairying;

2018
Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis.
    Journal of forensic and legal medicine, 2018, Volume: 59

    Topics: 3-Hydroxybutyric Acid; Acetone; Acidosis, Lactic; Alcoholism; Cerebrum; Fasting; Female; Fetal Blood

2018
Guiding Ketogenic Diet with Breath Acetone Sensors.
    Sensors (Basel, Switzerland), 2018, Oct-28, Volume: 18, Issue:11

    Topics: Acetone; Breath Tests; Calibration; Cohort Studies; Diet, Ketogenic; Female; Humans; Ketosis; Male;

2018
Ketone bodies upregulate endothelial connexin 43 (Cx43) gap junctions.
    Veterinary journal (London, England : 1997), 2013, Volume: 198, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Aorta; Blotting, Western; Cattle; Connexin 4

2013
(1)H-Nuclear magnetic resonance-based plasma metabolic profiling of dairy cows with clinical and subclinical ketosis.
    Journal of dairy science, 2014, Volume: 97, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Blood Glucose; Cattle; Cattle Diseases; Chol

2014
Determination of acetone in saliva by reversed-phase liquid chromatography with fluorescence detection and the monitoring of diabetes mellitus patients with ketoacidosis.
    Clinica chimica acta; international journal of clinical chemistry, 2014, Mar-20, Volume: 430

    Topics: Acetone; Adult; Aged; Chromatography, Reverse-Phase; Diabetes Mellitus; Female; Fluorescence; Humans

2014
Accuracy of milk ketone bodies from flow-injection analysis for the diagnosis of hyperketonemia in dairy cows.
    Journal of dairy science, 2014, Volume: 97, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Dietary F

2014
Study of the exhaled acetone in type 1 diabetes using quantum cascade laser spectroscopy.
    Analytical chemistry, 2015, Jan-06, Volume: 87, Issue:1

    Topics: Acetone; Adolescent; Adult; Blood Glucose; Breath Tests; Case-Control Studies; Diabetes Mellitus, Ty

2015
Development of Fourier transform mid-infrared calibrations to predict acetone, β-hydroxybutyrate, and citrate contents in bovine milk through a European dairy network.
    Journal of dairy science, 2016, Volume: 99, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Calibration; Cattle; Cattle Diseases; Citric Acid; Cost-Ben

2016
Postmortem biochemistry in suspected starvation-induced ketoacidosis.
    Journal of forensic and legal medicine, 2016, Volume: 42

    Topics: 3-Hydroxybutyric Acid; Acetone; Adult; Albumins; Biomarkers; Blood Urea Nitrogen; Creatinine; Female

2016
The (non)sense of routinely analysing beta-hydroxybutyric acid in forensic toxicology casework.
    Forensic science international, 2017, Volume: 274

    Topics: 3-Hydroxybutyric Acid; Acetone; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; K

2017
Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:2

    Topics: Acetone; Animals; Electron Spin Resonance Spectroscopy; Free Radicals; Immunohistochemistry; Ketosis

2008
Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH?
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:1

    Topics: Acetone; Animals; Blood Glucose; Cholesterol; Chronic Disease; Disease Models, Animal; Fatty Liver;

2010
Increased blood concentration of isopropanol in ketotic dairy cows and isopropanol production from acetone in the rumen.
    Animal science journal = Nihon chikusan Gakkaiho, 2009, Volume: 80, Issue:4

    Topics: 2-Propanol; Acetone; Animals; Cattle; Cattle Diseases; Female; Ketosis; Male; Rumen

2009
Repeated intoxication presenting with azotemia, elevated serum osmolal gap, and metabolic acidosis with high anion gap: differential diagnosis, management, and prognosis.
    International urology and nephrology, 2012, Volume: 44, Issue:1

    Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Acid-Base Equilibrium; Acidosis; Aged; Al

2012
Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 300, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Body Weight; Diet, Ketogenic; Diet, Protein-Restricted; Die

2011
Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples.
    Forensic science international, 2012, Jan-10, Volume: 214, Issue:1-3

    Topics: 3-Hydroxybutyric Acid; Acetone; Adult; Aged; Alcoholism; Biomarkers; Diabetic Ketoacidosis; Female;

2012
Blood, urine and vitreous isopropyl alcohol as biochemical markers in forensic investigations.
    Legal medicine (Tokyo, Japan), 2012, Volume: 14, Issue:1

    Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Biomarkers; Case-Control Studies; Flame I

2012
Postmortem detection of isopropanol in ketoacidosis.
    Journal of forensic sciences, 2012, Volume: 57, Issue:3

    Topics: 2-Propanol; Acetone; Biomarkers; Central Nervous System Depressants; Diagnosis, Differential; Ethano

2012
Routine detection of hyperketonemia in dairy cows using Fourier transform infrared spectroscopy analysis of β-hydroxybutyrate and acetone in milk in combination with test-day information.
    Journal of dairy science, 2012, Volume: 95, Issue:9

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Female; Humans; Ketosis; Milk; Par

2012
Genetic and nongenetic variation in plasma and milk β-hydroxybutyrate and milk acetone concentrations of early-lactation dairy cows.
    Journal of dairy science, 2012, Volume: 95, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Cattle; Cattle Diseases; Female; Genetic Variation; Ketosis

2012
Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient.
    Clinica chimica acta; international journal of clinical chemistry, 2013, Jan-16, Volume: 415

    Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetone; Adult; Alcoholism; Blood Glucose; Chronic Disease; Human

2013
Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone.
    Pediatric research, 2002, Volume: 52, Issue:3

    Topics: Acetone; Anticonvulsants; Breath Tests; Child; Diet; Epilepsy; Humans; Ketone Bodies; Ketosis; Time

2002
Use of threshold serum and milk ketone concentrations to identify risk for ketosis and endometritis in high-yielding dairy cows.
    American journal of veterinary research, 2003, Volume: 64, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetone; Animal Feed; Animal Husbandry; Animals; Cattle; Dairying; Endometrio

2003
[Genesis and therapy of postoperative acetonemia].
    Arztliche Wochenschrift, 1953, Jul-31, Volume: 8, Issue:31

    Topics: Acetone; Blood; Humans; Ketosis; Postoperative Period

1953
[False positive reaction of acetonuria in an isoniazid solution, as determined with the Imbert reagent].
    "Laboratorio;" analisis clinicos, bacteriologia, inmunologia, parasitologia, hematologia, anatomia patologica, quimica clinica, 1954, Volume: 18, Issue:103

    Topics: Acetone; False Positive Reactions; Humans; Isoniazid; Ketosis; Niacin; Nicotinic Acids; Pharmaceutic

1954
[Periodic vomiting with acetonuria].
    La Revue du praticien, 1954, Nov-21, Volume: 4, Issue:30

    Topics: Acetone; Humans; Ketosis; Urine; Vomiting

1954
[Levulose utilization in acidotic diabetes mellitus. I. Analysis of acetonuria and glucosuria].
    Zeitschrift fur klinische Medizin, 1955, Volume: 153, Issue:4

    Topics: Acetone; Diabetes Complications; Diabetes Mellitus; Fructose; Glycosuria; Humans; Ketosis; Urine

1955
Acetonuria in pregnancy.
    Journal - Newark Beth Israel Hospital, 1961, Volume: 12

    Topics: Acetone; Humans; Ketosis; Pregnancy; Pregnancy Complications

1961
[SEVERE DIABETIC COMA WITHOUT KETOACIDOSIS. CASE REPORT AND REVIEW].
    Ugeskrift for laeger, 1964, Aug-06, Volume: 126

    Topics: Acetone; Acidosis; Blood Chemical Analysis; Dehydration; Diabetic Coma; Humans; Infusions, Parentera

1964
A CASE OF PONTINE TUMOR ASSOCIATED WITH REPEATED EPISODES OF HYPERVENTILATION AND KETOSIS.
    Paediatria Universitatis Tokyo, 1964, Volume: 10

    Topics: Acetone; Acidosis; Astrocytoma; Blood Chemical Analysis; Brain Neoplasms; Brain Stem Neoplasms; Chil

1964
[Vilém Petters, pioneer in research on acetonuria].
    Casopis lekaru ceskych, 1952, Jul-11, Volume: 91, Issue:28

    Topics: Acetone; History, 19th Century; Ketosis; Urine

1952
Aminoacetone induces loss of ferritin ferroxidase and iron uptake activities.
    Free radical research, 2003, Volume: 37, Issue:10

    Topics: Acetone; Amine Oxidase (Copper-Containing); Amino Acids; Animals; Apoferritins; Ceruloplasmin; Diabe

2003
Deficiency diseases, particularly acetonaemia in cattle.
    The Veterinary record, 1950, Dec-02, Volume: 62, Issue:48

    Topics: Acetone; Animals; Blood; Cattle; Ketosis

1950
The clinical syndrome known as "acetonaemia".
    The Veterinary record, 1950, Dec-30, Volume: 62, Issue:52

    Topics: Acetone; Animals; Blood; Cattle; Ketosis

1950
The treatment of acetonemia in cattle by continuous intravenous injection of glucose.
    The Cornell veterinarian, 1951, Volume: 41, Issue:1

    Topics: Acetone; Animals; Blood; Cattle; Glucose; Humans; Injections, Intravenous; Ketosis

1951
[A fatal case of acetonemia].
    Archives francaises de pediatrie, 1951, Volume: 8, Issue:2

    Topics: Acetone; Blood; Humans; Ketosis

1951
Hormonal hypothesis of prepartum and postpartum acetonemia in dairy cattle.
    Veterinary medicine, 1951, Volume: 46, Issue:8

    Topics: Acetone; Animals; Blood; Cattle; Female; Humans; Ketosis; Postpartum Period

1951
[Absence of acetone in the blood and fresh excreted urine during ketosis].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1952, Volume: 53, Issue:3

    Topics: Acetone; Acidosis; Body Fluids; Humans; Ketone Bodies; Ketosis

1952
A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats.
    Epilepsy research, 2006, Volume: 71, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Allyl Compounds; Analysis of Variance; Animals; Antic

2006
Screening for subclinical ketosis in dairy cattle by Fourier transform infrared spectrometry.
    Journal of dairy science, 2007, Volume: 90, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Calibration; Cattle; Cattle Diseases; Dairyi

2007
The anticonvulsant activity of acetone does not depend upon its metabolites.
    Epilepsia, 2008, Volume: 49, Issue:5

    Topics: Acetone; Animals; Anticonvulsants; Blood-Brain Barrier; Disease Models, Animal; Humans; Injections,

2008
A rapid quantitative colorimetric determination of blood acetone applied to the assessment of ketosis in fasted pregnant ewes.
    The Onderstepoort journal of veterinary research, 1981, Volume: 48, Issue:1

    Topics: Acetone; Acidosis; Animals; Colorimetry; Female; Ketones; Ketosis; Pregnancy; Pregnancy Complication

1981
Breath acetone in congestive heart failure.
    The American journal of cardiology, 1995, Nov-15, Volume: 76, Issue:14

    Topics: Acetone; Adult; Aged; Breath Tests; Chromatography, Gas; Female; Heart Failure; Humans; Ketosis; Lin

1995
Relationship between milk acetone and milk yield in individual cows.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1994, Volume: 41, Issue:2

    Topics: Acetone; Animals; Cattle; Cattle Diseases; Female; Ketosis; Lactation; Milk; Regression Analysis

1994
Alcoholic ketoacidosis as a cause of death in forensic cases.
    Forensic science international, 1995, Oct-30, Volume: 75, Issue:2-3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis

1995
Evaluation of additional acetone and urea analyses, and of the fat-lactose-quotient in cow milk samples in the herd recording system in Norway.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1996, Volume: 43, Issue:3

    Topics: Acetone; Animals; Cattle; Cattle Diseases; Female; Incidence; Ketosis; Lactation; Lactose; Lipid Met

1996
In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production.
    American journal of veterinary research, 1996, Volume: 57, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Cat Diseases; Cats; Erythrocytes; Female; Gl

1996
Evaluation of bulk milk analyses of acetone, urea, and the fat-lactose-quotient as diagnostic aids in preventive veterinary medicine.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1996, Volume: 43, Issue:5

    Topics: Acetone; Animals; Cattle; Cattle Diseases; Female; Ketosis; Lactose; Lipid Metabolism; Lipids; Milk;

1996
Detection of ketosis in dairy cows by analysis of exhaled breath.
    The veterinary quarterly, 1996, Volume: 18, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Breath Tests; Cattle; Cattle Diseases; Chromatography, Gas;

1996
Ketoacidosis and lactic acidosis--frequent causes of death in chronic alcoholics?
    International journal of legal medicine, 1998, Volume: 111, Issue:3

    Topics: Acetone; Acidosis, Lactic; Adult; Alcoholic Intoxication; Alcoholism; Autopsy; Cause of Death; Diabe

1998
Alcoholic ketoacidosis at autopsy.
    Journal of forensic sciences, 1998, Volume: 43, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis

1998
Screening of dairy cows for ketosis by use of infrared spectroscopy and multivariate calibration.
    Journal of dairy science, 1999, Volume: 82, Issue:9

    Topics: Acetone; Animals; Calibration; Cattle; Cattle Diseases; Female; Ketosis; Mathematics; Milk; Sensitiv

1999
Determination of acetone in cow milk by Fourier transform infrared spectroscopy for the detection of subclinical ketosis.
    Journal of dairy science, 2001, Volume: 84, Issue:3

    Topics: Acetone; Animals; Cattle; Cattle Diseases; Female; Ketosis; Milk; Models, Biological; Reproducibilit

2001
Ketone bodies in milk and blood of dairy cows: relationship between concentrations and utilization for detection of subclinical ketosis.
    Journal of dairy science, 2001, Volume: 84, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Cattle; Cattle Diseases; Female; Ketone Bodi

2001
Concentrations of ketones in milk in early lactation, and reproductive performance of dairy cows.
    The Veterinary record, 2001, Jun-23, Volume: 148, Issue:25

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Case-Control Studies; Cattle; Cattle Diseases; Dairying; Fe

2001
Breath acetone as a measure of systemic ketosis assessed in a rat model of the ketogenic diet.
    Clinical chemistry, 2002, Volume: 48, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Breath Tests; Chromatography, Gas; Dietary Carbohydrates; D

2002
Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adult; Breath Tests; Diet; Dietary Fats; Epilepsy; Fa

2002
[Use of sodium acetate in feed rations in ketotic cows].
    Veterinarni medicina, 1989, Volume: 34, Issue:10

    Topics: Acetates; Acetic Acid; Acetone; Acidosis; Animal Feed; Animals; Cattle; Cattle Diseases; Female; Ket

1989
[Levels of acetone in cow's milk after calving in herds from the West Slovakia region].
    Veterinarni medicina, 1988, Volume: 33, Issue:5

    Topics: Acetone; Acidosis; Animals; Cattle; Cattle Diseases; Female; Ketosis; Milk; Pregnancy

1988
Combined effect of a small dose of ethanol and 36 hr fasting on blood-glucose response, breath-acetone profiles and platelet function in healthy men.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1987, Volume: 22, Issue:3

    Topics: Acetone; Acidosis; Adult; Blood Glucose; Breath Tests; Ethanol; Fasting; Humans; Hypoglycemia; Ketos

1987
Can marked hyperglycemia occur without ketosis?
    Clinical and investigative medicine. Medecine clinique et experimentale, 1985, Volume: 8, Issue:4

    Topics: Acetone; Acidosis; Brain; Diabetic Coma; Glucose; Glycerides; Glycerol; Glycogen; Humans; Hyperglyce

1985