Page last updated: 2024-10-31

metronidazole and CACH Syndrome

metronidazole has been researched along with CACH Syndrome in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Armstrong, AG1
Kalia, R1
Fukumoto, T1
Katada, F1
Sato, S1
Shibayama, H1
Murayama, S1
Fukutake, T1
Demel, SL1
Jovin, TG1
Jadhav, AP1

Other Studies

3 other studies available for metronidazole and CACH Syndrome

ArticleYear
Metronidazole-Induced Leukoencephalopathy Presenting as Catatonia.
    The primary care companion for CNS disorders, 2021, 09-23, Volume: 23, Issue:5

    Topics: Catatonia; Humans; Leukoencephalopathies; Metronidazole

2021
[A case of acute leukoencephalopathy induced by a combination of 5-fluorouracil and metronidazole].
    Rinsho shinkeigaku = Clinical neurology, 2018, Feb-28, Volume: 58, Issue:2

    Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Drug Therapy, Combinatio

2018
Metronidazole toxicity presenting with acute onset of aphasia and right sided weakness.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:7

    Topics: Adult; Anti-Bacterial Agents; Aphasia; Bacteremia; Clostridioides difficile; Enterocolitis, Pseudome

2015