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risedronic acid and Osseous Paget's Disease

risedronic acid has been researched along with Osseous Paget's Disease in 48 studies

Risedronic Acid: A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.

Research Excerpts

ExcerptRelevanceReference
"Although etidronate is effective, risedronate offers a shorter duration of therapy, better and longer-lasting remission, significant reductions in pain, and provides additional remission in subjects who exhibited an incomplete response to previous etidronate treatment."5.09A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group. ( Axelrod, DW; Bekker, PJ; Brown, JP; Hoseyni, MS; Miller, PD; Siris, ES, 1999)
"Studies of risedronate were obtained from the MEDLINE database (1966 to the present) of references using risedronate, risedronic acid, osteoporosis, and human subject as keywords."4.81Risedronate: a clinical review. ( Crandall, C, 2001)
"5 mg once daily was well tolerated by patients with PDB, even though the dosage was seven times higher than that approved for the treatment of osteoporosis in Japan (2."2.75Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget's disease of bone. ( Hashimoto, J; Takata, S; Yoh, K; Yoshimura, N, 2010)
"Zoledronic acid (ZOL) is a potent bisphosphonate that produces a rapid and complete control of the increased bone turnover of Paget's disease."2.73Long-term control of bone turnover in Paget's disease with zoledronic acid and risedronate. ( Brown, JP; Curiel, MD; Devogelaer, JP; Eriksen, EF; Fashola, T; Fraser, WD; Hooper, M; Hosking, D; Lyles, K; Miller, P; Pak, J; Reid, IR; Saidi, Y; Su, G; Zelenakas, K, 2007)
"Zoledronic acid was associated with a shorter median time to a first therapeutic response (64 vs."2.71Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease. ( Brown, JP; Fraser, W; Hosking, D; Luchi, M; Lyles, K; Mesenbrink, P; Miller, P; Pak, J; Reid, IR; Richardson, P; Saidi, Y; Su, G; Zelenakas, K, 2005)
" The data show that there is a dose-response with risedronate: patients who received 30 mg oral risedronate for 28 days benefited most, with a mean percentage decrease in AP excess of 72."2.69Risedronate, a highly effective, short-term oral treatment for Paget's disease: a dose-response study. ( Bekker, PJ; Brown, JP; Hosking, DJ; Johnson, TD; Johnston, CC; Reginster, J; Ryan, WG; Ste-Marie, L, 1999)
" Six BPs are currently approved by the US Food and Drug Administration (FDA) for the treatment of Paget disease, and each has unique characteristics, such as response rates and requirements for dosage and administration, relevant to clinical outcome."2.44Paget disease of bone: therapeutic options. ( Silverman, SL, 2008)
" Intravenous pamidronate is efficacious and has long been available, but its use is hindered by an impractical recommended dosing regimen of 30 mg IV over 4 h for three consecutive days."2.44A review of Paget's disease of bone with a focus on the efficacy and safety of zoledronic acid 5 mg. ( Abelson, A, 2008)
" Whenever the initial dose failed to produce remission, the dosage was increased to twice a week the respective dose."1.51Long-term control of Paget's disease of bone with low-dose, once-weekly, oral bisphosphonate preparations, in a "real world" setting. ( Abu Tailakh, M; Liel, Y, 2019)
"Paget disease of bone is the most common metabolic bone disease after osteoporosis, affecting 2-4% of adults over 55 years of age."1.38Paget disease of bone - an update. ( Britton, C; Walsh, J, 2012)
"Pamidronate treatment (60 mg/day for 3 days) was repeated in patients without evidence of PDB remission at day 120."1.32Risedronate and pamidronate treatment in the clinical management of patients with severe Paget's disease of bone and acquired resistance to bisphosphonates. ( Mossetti, G; Nunziata, V; Rendina, D; Sorrentino, M; Viceconti, R, 2004)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (25.00)18.2507
2000's29 (60.42)29.6817
2010's6 (12.50)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
Ralston, SH1
Liel, Y2
Abu Tailakh, M1
Ohara, M1
Imanishi, Y1
Nagata, Y1
Ishii, A1
Kobayashi, I1
Mori, K1
Ito, M1
Miki, T1
Nishizawa, Y1
Inaba, M1
Silverman, SL1
Torres, J1
Tamimi, F1
Garcia, I1
Herrero, A1
Rivera, B1
Sobrino, JA1
Hernández, G1
Yoh, K1
Takata, S2
Yoshimura, N1
Hashimoto, J1
Woo, JH1
Kim, S1
Choi, SJ1
Lee, YH1
Ji, JD1
Song, GG1
Britton, C1
Walsh, J1
Nishida, Y1
Yamada, Y1
Tsukushi, S1
Sugiura, H1
Urakawa, H1
Ishiguro, N1
Fournier, P1
Boissier, S1
Filleur, S1
Guglielmi, J1
Cabon, F1
Colombel, M1
Clézardin, P1
Rendina, D3
Mossetti, G3
Viceconti, R2
Sorrentino, M1
Nunziata, V2
De Filippo, G2
Di Domenico, G1
Cioffi, M1
Postiglione, L1
Brixen, KT1
Abrahamsen, B1
Kassem, MS1
Mosekilde, L1
Orcel, P1
Rousière, M1
Barrera, BA1
Wilton, L1
Harris, S1
Shakir, SA1
Reid, IR2
Miller, P2
Lyles, K2
Fraser, W1
Brown, JP8
Saidi, Y2
Mesenbrink, P1
Su, G2
Pak, J2
Zelenakas, K2
Luchi, M1
Richardson, P1
Hosking, D3
Füessl, HS1
Whitson, HE1
Lobaugh, B1
Lyles, KW1
Krane, SM1
Fraser, WD1
Curiel, MD1
Devogelaer, JP1
Hooper, M1
Fashola, T1
Eriksen, EF1
Zillikens, MC1
Ginai, AZ1
Pols, HA1
Abelson, A1
Olmos Martínez, JM1
Hernández Hernández, JL1
Martínez García, J1
González Macías, J1
Kylstra, JW1
Bekker, PJ5
Axelrod, DW2
Siris, ES3
Altman, RD2
Singer, FR3
Hosking, DJ4
Eusebio, RA4
Chines, AA3
Patel, S1
Pearson, D1
Bhallah, A1
Maslanka, W1
White, DA1
Clemens, TL1
Johnston, CC2
Lang, R1
McClung, MR1
Mallette, LE1
Miller, PD3
Ryan, WG2
Tucci, JR1
Ste-Marie, L1
Reginster, J1
Johnson, TD1
Hoseyni, MS1
Hussar, DA1
Myers, WR1
Ritter-Hrncirik, C1
Hayes, CW1
Crandall, C1
Drake, WM1
Kendler, DL1
Dunn, CJ1
Goa, KL1
Chapurlat, RD1
Delmas, PD1
Umland, EM1
Boyce, EG1
Bannwarth, B1
Shiraki, M1

Reviews

14 reviews available for risedronic acid and Osseous Paget's Disease

ArticleYear
Paget disease of bone: therapeutic options.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2008, Volume: 14, Issue:5

    Topics: Alendronate; Alkaline Phosphatase; Anti-Inflammatory Agents; Diphosphonates; Etidronic Acid; Humans;

2008
[Pharmacological treatment of osteitis deformans (Paget's bone disease)].
    Ugeskrift for laeger, 2005, Feb-28, Volume: 167, Issue:9

    Topics: Alendronate; Analgesics, Non-Narcotic; Antimetabolites; Calcitonin; Clodronic Acid; Diphosphonates;

2005
[Paget's disease and its therapeutic management].
    Presse medicale (Paris, France : 1983), 2005, Apr-23, Volume: 34, Issue:8

    Topics: Administration, Oral; Alkaline Phosphatase; Biomarkers; Diphosphonates; Etidronic Acid; Follow-Up St

2005
Pharmacological therapy of Paget's and other metabolic bone diseases.
    Bone, 2006, Volume: 38, Issue:2 Suppl 2

    Topics: Bone Density Conservation Agents; Bone Resorption; Clinical Trials as Topic; Diphosphonates; Etidron

2006
[Therapeutic effects of risedronate on Paget's disease of bone].
    Clinical calcium, 2006, Volume: 16, Issue:9

    Topics: Aged; Bone Density Conservation Agents; Clinical Trials as Topic; Etidronic Acid; Humans; Male; Oste

2006
A review of Paget's disease of bone with a focus on the efficacy and safety of zoledronic acid 5 mg.
    Current medical research and opinion, 2008, Volume: 24, Issue:3

    Topics: Aged; Bone Density Conservation Agents; Diphosphonates; Disease Progression; Etidronic Acid; Humans;

2008
Prediction and assessment of the response of Paget's disease to bisphosphonate treatment.
    Bone, 1999, Volume: 24, Issue:5 Suppl

    Topics: Alkaline Phosphatase; Bone Resorption; Diphosphonates; Etidronic Acid; Half-Life; Humans; Osteitis D

1999
The use of risedronate in Paget's disease.
    Bone, 1999, Volume: 24, Issue:5 Suppl

    Topics: Alkaline Phosphatase; Bone Resorption; Clinical Trials as Topic; Etidronic Acid; Fibrous Dysplasia,

1999
Risedronate: a clinical review.
    Archives of internal medicine, 2001, Feb-12, Volume: 161, Issue:3

    Topics: Animals; Bone and Bones; Bone Density; Breast Neoplasms; Calcium Channel Blockers; Etidronic Acid; F

2001
Consensus statement on the modern therapy of Paget's disease of bone from a Western Osteoporosis Alliance symposium. Biannual Foothills Meeting on Osteoporosis, Calgary, Alberta, Canada, September 9-10, 2000.
    Clinical therapeutics, 2001, Volume: 23, Issue:4

    Topics: Alendronate; Alkaline Phosphatase; Clinical Trials as Topic; Diphosphonates; Etidronic Acid; Humans;

2001
Risedronate: a review of its pharmacological properties and clinical use in resorptive bone disease.
    Drugs, 2001, Volume: 61, Issue:5

    Topics: Bone and Bones; Bone Density; Calcium Channel Blockers; Etidronic Acid; Female; Half-Life; Humans; I

2001
Risedronate: clinical usage.
    International journal of clinical practice, 2001, Volume: 55, Issue:4

    Topics: Bone Density; Bone Resorption; Calcium Channel Blockers; Etidronic Acid; Female; Humans; Male; Ostei

2001
Risedronate: a new oral bisphosphonate.
    Clinical therapeutics, 2001, Volume: 23, Issue:9

    Topics: Administration, Oral; Alendronate; Calcium Channel Blockers; Diphosphonates; Etidronic Acid; Female;

2001
[Risedronate: clinical usage].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 3

    Topics: Bone Density; Clinical Trials as Topic; Etidronic Acid; Femoral Neck Fractures; Fractures, Stress; H

2002

Trials

9 trials available for risedronic acid and Osseous Paget's Disease

ArticleYear
Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget's disease of bone.
    Journal of bone and mineral metabolism, 2010, Volume: 28, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Etidronic Acid; Female; Humans; Ma

2010
Midterm outcome of risedronate therapy for patients with Paget's disease of bone in the central part of Japan.
    Clinical rheumatology, 2013, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and Bones; Bone Density Conservation Agen

2013
Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease.
    The New England journal of medicine, 2005, Sep-01, Volume: 353, Issue:9

    Topics: Administration, Oral; Aged; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Remodeling; Dipho

2005
Is a single infusion of zoledronic acid more effective than oral risedronate for the treatment of patients with Paget's disease?
    Nature clinical practice. Rheumatology, 2006, Volume: 2, Issue:4

    Topics: Administration, Oral; Adult; Bone Density Conservation Agents; Diphosphonates; Dose-Response Relatio

2006
Long-term control of bone turnover in Paget's disease with zoledronic acid and risedronate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alkaline Phosphatase; Bone and Bones; Bone Density Co

2007
Risedronate in Paget's disease: preliminary results of a multicenter study.
    Seminars in arthritis and rheumatism, 1994, Volume: 23, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Etidronic Acid; Humans; Middle Age

1994
Risedronate in the treatment of Paget's disease of bone: an open label, multicenter study.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Biomarkers; Calcium Chan

1998
Risedronate, a highly effective, short-term oral treatment for Paget's disease: a dose-response study.
    Calcified tissue international, 1999, Volume: 64, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Calcium Channel Blockers; Consumer Product Safety; Do

1999
A randomized, double-blind comparison of risedronate and etidronate in the treatment of Paget's disease of bone. Paget's Risedronate/Etidronate Study Group.
    The American journal of medicine, 1999, Volume: 106, Issue:5

    Topics: Administration, Oral; Aged; Alkaline Phosphatase; Bone and Bones; Calcium Channel Blockers; Double-B

1999

Other Studies

25 other studies available for risedronic acid and Osseous Paget's Disease

ArticleYear
Bisphosphonates in the management of Paget's disease.
    Bone, 2020, Volume: 138

    Topics: Alendronate; Diphosphonates; Humans; Osteitis Deformans; Risedronic Acid; Zoledronic Acid

2020
Long-term control of Paget's disease of bone with low-dose, once-weekly, oral bisphosphonate preparations, in a "real world" setting.
    Endocrine, 2019, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Female; Humans; Male;

2019
Clinical efficacy of oral risedronate therapy in Japanese patients with Paget's disease of bone.
    Journal of bone and mineral metabolism, 2015, Volume: 33, Issue:5

    Topics: Administration, Oral; Aged; Alkaline Phosphatase; Asian People; Biomarkers; Bone and Bones; Bone Den

2015
Dental implants in a patient with Paget disease under bisphosphonate treatment: a case report.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2009, Volume: 107, Issue:3

    Topics: Administration, Oral; Bone Density Conservation Agents; Dental Implantation, Endosseous; Dental Pros

2009
Diagnosis of Paget's disease of the pelvis using F-18 FDG PET/CT.
    International journal of rheumatic diseases, 2010, Volume: 13, Issue:4

    Topics: Asymptomatic Diseases; Bone Density Conservation Agents; Diagnosis, Differential; Etidronic Acid; Fe

2010
Paget disease of bone - an update.
    Australian family physician, 2012, Volume: 41, Issue:3

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Diphosphonates; Etidronic Ac

2012
Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats.
    Cancer research, 2002, Nov-15, Volume: 62, Issue:22

    Topics: Angiogenesis Inhibitors; Animals; Bone and Bones; Cell Division; Cells, Cultured; Clodronic Acid; Di

2002
Risedronate and pamidronate treatment in the clinical management of patients with severe Paget's disease of bone and acquired resistance to bisphosphonates.
    Calcified tissue international, 2004, Volume: 75, Issue:3

    Topics: Administration, Oral; Alkaline Phosphatase; Calcitriol; Clodronic Acid; Diphosphonates; Drug Toleran

2004
Interleukin-6 and osteoprotegerin systems in Paget's disease of bone: relationship to risedronate treatment.
    Bone, 2005, Volume: 36, Issue:3

    Topics: Aged; Etidronic Acid; Female; Glycoproteins; Humans; Interleukin-6; Male; Middle Aged; Osteitis Defo

2005
Prescription-event monitoring study on 13,164 patients prescribed risedronate in primary care in England.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:12

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Bone Density Conservation Agents;

2005
Paget's disease and bisphosphonates.
    The New England journal of medicine, 2005, Dec-15, Volume: 353, Issue:24

    Topics: Administration, Oral; Alendronate; Cost-Benefit Analysis; Diphosphonates; Drug Administration Schedu

2005
Paget's disease and bisphosphonates.
    The New England journal of medicine, 2005, Dec-15, Volume: 353, Issue:24

    Topics: Administration, Oral; Alkaline Phosphatase; Diphosphonates; Disease Progression; Etidronic Acid; Hum

2005
[Optimizing therapy in Paget disease].
    MMW Fortschritte der Medizin, 2005, Dec-15, Volume: 147, Issue:51-52

    Topics: Administration, Oral; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, Combination; E

2005
Severe hypocalcemia following bisphosphonate treatment in a patient with Paget's disease of bone.
    Bone, 2006, Volume: 39, Issue:4

    Topics: Bone and Bones; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid; Female; Humans; Hy

2006
[Substance properties of zoledronate make it possible: bisphosphonate therapy only once yearly].
    MMW Fortschritte der Medizin, 2006, Jun-22, Volume: 148, Issue:25

    Topics: Aged; Aged, 80 and over; Alendronate; Biological Availability; Bone Density Conservation Agents; Dip

2006
[A young woman with headaches and skull anomalies: a long road to the diagnosis 'Paget's disease'].
    Nederlands tijdschrift voor geneeskunde, 2006, Sep-30, Volume: 150, Issue:39

    Topics: Adult; Alkaline Phosphatase; Bone Density Conservation Agents; Diagnosis, Differential; Etidronic Ac

2006
[Radius shaft fracture in a 31-year old man].
    Revista clinica espanola, 2008, Volume: 208, Issue:2

    Topics: Adult; Bone Density Conservation Agents; Etidronic Acid; Humans; Male; Osteitis Deformans; Radiograp

2008
Paget's disease of bone: reduction of disease activity with oral risedronate.
    Bone, 1998, Volume: 22, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alkaline Phosphatase; Calcium; Calcium Channel Blocke

1998
Changes in bone mineral density in patients with Paget's disease treated with risedronate.
    Annals of the rheumatic diseases, 1997, Volume: 56, Issue:7

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Bone Density; Bone Remodeling; Calcium Channel Bloc

1997
Risedronate released for Paget's disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, May-15, Volume: 55, Issue:10

    Topics: Calcium Channel Blockers; Drug Approval; Etidronic Acid; Humans; Osteitis Deformans; Risedronic Acid

1998
Risedronate, a highly effective oral agent in the treatment of patients with severe Paget's disease.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:6

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Calcitriol; Calcium; Calcium Channel Blockers; Creati

1998
Risedronate for Paget's disease of bone.
    The Medical letter on drugs and therapeutics, 1998, Aug-28, Volume: 40, Issue:1034

    Topics: Administration, Oral; Aged; Bone Resorption; Calcium Channel Blockers; Clinical Trials as Topic; Dia

1998
New drugs 99, Part III.
    Nursing, 1999, Volume: 29, Issue:6

    Topics: Alkynes; Anti-HIV Agents; Antibiotics, Antitubercular; Antibodies, Monoclonal; Antibodies, Monoclona

1999
Improvement of pagetic bone lesions with risedronate treatment: a radiologic study.
    Bone, 2000, Volume: 26, Issue:3

    Topics: Aged; Etidronic Acid; Female; Humans; Male; Middle Aged; Osteitis Deformans; Radiography; Risedronic

2000
[Risedronate, a new diphosphonate in osteoporosis and Paget's disease].
    Presse medicale (Paris, France : 1983), 2002, Mar-02, Volume: 31, Issue:8

    Topics: Aged; Calcium Channel Blockers; Cortisone; Costs and Cost Analysis; Double-Blind Method; Etidronic A

2002