gentamicin has been researched along with Drug-Induced Cochlear Toxicity in 30 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study intended to explore acupuncture's protective effects and mechanism of treatment in addressing ototoxicity induced by gentamicin (GM) in aged mice." | 9.51 | Acupuncture Attenuates Ototoxicity Induced by Gentamicin in Mice. ( Cao, L; Guan, N; Han, M; Tang, Y; Yu, Y, 2022) |
| "To emphasize the risk of gentamicin ototoxicity and suggest alternative antibiotics in penicillin-allergic patients undergoing surgery." | 8.31 | Debilitating Gentamicin Ototoxicity: Case Report and Recommendations Against Routine Use in Surgical Prophylaxis. ( Gubbels, SP; Kalmanson, OA; Kiser, TH; McLoughlin, KC, 2023) |
| " However, the potential protective effects of taxifolin against gentamicin-induced ototoxicity have not been confirmed." | 8.12 | Ameliorative effect of taxifolin on gentamicin-induced ototoxicity via down-regulation of apoptotic pathways in mouse cochlear UB/OC-2 cells. ( Hsu, CJ; Lin, CC; Lin, HY; Lin, JN; Tseng, GF; Wang, JS; Wen, YH; Wu, HP; Yu, SH, 2022) |
| "Gentamicin (GM) is a commonly used antibiotic, and ototoxicity is one of its side effects." | 8.02 | Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway. ( Li, G; Niu, P; Pan, C; Sun, J; Sun, Y; Tang, X; Wang, S, 2021) |
| "The first identified reference of quinine ototoxicity was from 1824." | 8.02 | Quinine in Otology and Neurotology: Ototoxicity and Historic Role in Therapy. ( Dias-Silva, N; Miguéis, J; Pita, JR; Semedo, MG, 2021) |
| "We aimed to confirm the synergistic ototoxicity of combined gentamicin and low-dose irradiation treatment and identify the underlying molecular mechanisms using an in vitro model." | 7.96 | Synergistic Ototoxicity of Gentamicin and Low-Dose Irradiation: Molecular Basis and Clinical Significance. ( Low, WK; Tan, MGK; Teng, SW, 2020) |
| "Gentamicin-induced cochlear hair cell ototoxicity, such as oxidative stress and apoptosis, could be attenuated by mouse inner ear stem cells (IESCs)." | 7.96 | Exosomes derived from mouse inner ear stem cells attenuate gentamicin-induced ototoxicity in vitro through the miR-182-5p/FOXO3 axis. ( Cai, C; Hu, P; Lai, R; Wang, Q; Wu, W, 2020) |
| "Gentamicin is a widely used antibiotic for the treatment of gram-negative bacterial infections; however, its use often results in significant and permanent hearing loss." | 7.91 | Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K-Akt pathway. ( Bodmer, D; Horvath, L; Kucharava, K; Petkovic, V; Sekulic-Jablanovic, M, 2019) |
| "Gentamicin can lead to cochlear hair cells associated ototoxicity by inducing apoptosis and oxidative stress, which can be alleviated by baicalin, one flavonoid extracted from the root of Scutellaria baicalensis." | 7.91 | Baicalin attenuates gentamicin-induced cochlear hair cell ototoxicity. ( Yu, J; Zhang, X, 2019) |
| "It is known that ototoxicity is the main cause of toxicity induced by aminoglycoside antibiotics." | 5.72 | Salicylate attenuates gentamicin-induced ototoxicity and facilitates the recovery in the basilar papilla of the lizard Podarcis siculus. ( Avallone, B; Fogliano, C; Motta, CM, 2022) |
| " In the present study, we compared the in vivo toxic effects of three aminoglycosides, gentamicin, amikacin, and etimicin, in zebrafish embryos." | 5.62 | A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos. ( Chen, D; Han, Y; Jiang, H; Jing, L; Li, R; Qian, X; Shao, W; Yin, Y; Zhong, D, 2021) |
| "Calcium dobesilate is a pharmacologically active agent used to treat many disorders due to its vasoprotective and antioxidant effects." | 5.56 | Does Calcium Dobesilate Have Therapeutic Effect on Gentamicin-induced Cochlear Nerve Ototoxicity? An Experimental Study. ( Altunay, ZÖ; Ataş, A; Çınar, Z; Edizer, DT; Gül, M; Yiğit, Ö, 2020) |
| "The study intended to explore acupuncture's protective effects and mechanism of treatment in addressing ototoxicity induced by gentamicin (GM) in aged mice." | 5.51 | Acupuncture Attenuates Ototoxicity Induced by Gentamicin in Mice. ( Cao, L; Guan, N; Han, M; Tang, Y; Yu, Y, 2022) |
| "The ototoxicity of gentamicin and cisplatin can be evaluated with a Schwann cell model to screen for otoprotective agents that can be encapsulated into poly (lactic-co-glycolic acid) (PLGA) microparticles for drug delivery to the inner ear." | 4.31 | Designing a Prolonged Method of Therapeutic Delivery to Support Rehabilitation From Ototoxic Damage in a Schwann Cell Model. ( Echanique, KA; Hoffman, LF; Hong, MK; Kita, AE, 2023) |
| "To emphasize the risk of gentamicin ototoxicity and suggest alternative antibiotics in penicillin-allergic patients undergoing surgery." | 4.31 | Debilitating Gentamicin Ototoxicity: Case Report and Recommendations Against Routine Use in Surgical Prophylaxis. ( Gubbels, SP; Kalmanson, OA; Kiser, TH; McLoughlin, KC, 2023) |
| " However, the potential protective effects of taxifolin against gentamicin-induced ototoxicity have not been confirmed." | 4.12 | Ameliorative effect of taxifolin on gentamicin-induced ototoxicity via down-regulation of apoptotic pathways in mouse cochlear UB/OC-2 cells. ( Hsu, CJ; Lin, CC; Lin, HY; Lin, JN; Tseng, GF; Wang, JS; Wen, YH; Wu, HP; Yu, SH, 2022) |
| "Gentamicin is a widely used aminoglycoside with ototoxicity as a known adverse effect." | 4.12 | A Prospective Study on the Vestibular Toxicity of Gentamicin in a Clinical Setting. ( Chatterton, S; Cremer, PD; Kotsiou, G; Migliaccio, AA; Satyan, H; Todd, CJ; Wang, C, 2022) |
| "Gentamicin (GM) is a commonly used antibiotic, and ototoxicity is one of its side effects." | 4.02 | Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway. ( Li, G; Niu, P; Pan, C; Sun, J; Sun, Y; Tang, X; Wang, S, 2021) |
| "The first identified reference of quinine ototoxicity was from 1824." | 4.02 | Quinine in Otology and Neurotology: Ototoxicity and Historic Role in Therapy. ( Dias-Silva, N; Miguéis, J; Pita, JR; Semedo, MG, 2021) |
| "We aimed to confirm the synergistic ototoxicity of combined gentamicin and low-dose irradiation treatment and identify the underlying molecular mechanisms using an in vitro model." | 3.96 | Synergistic Ototoxicity of Gentamicin and Low-Dose Irradiation: Molecular Basis and Clinical Significance. ( Low, WK; Tan, MGK; Teng, SW, 2020) |
| "Gentamicin-induced cochlear hair cell ototoxicity, such as oxidative stress and apoptosis, could be attenuated by mouse inner ear stem cells (IESCs)." | 3.96 | Exosomes derived from mouse inner ear stem cells attenuate gentamicin-induced ototoxicity in vitro through the miR-182-5p/FOXO3 axis. ( Cai, C; Hu, P; Lai, R; Wang, Q; Wu, W, 2020) |
| "Gentamicin has proven to be a very successful treatment for bacterial infection, but it also can cause adverse effects, especially ototoxicity, which is irreversible." | 3.96 | Saliva versus Plasma Therapeutic Drug Monitoring of Gentamicin in Jordanian Preterm Infants. Development of a Physiologically-Based Pharmacokinetic (PBPK) Model and Validation of Class II Drugs of Salivary Excretion Classification System. ( Al-Adham, I; Al-Ghazawi, A; Alsmadi, M; Aqrabawi, H; Awaysheh, F; Bani-Domi, R; Hamadi, S; Idkaidek, N; Rabayah, A, 2020) |
| "Gentamicin is a widely used antibiotic for the treatment of gram-negative bacterial infections; however, its use often results in significant and permanent hearing loss." | 3.91 | Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K-Akt pathway. ( Bodmer, D; Horvath, L; Kucharava, K; Petkovic, V; Sekulic-Jablanovic, M, 2019) |
| "Gentamicin can lead to cochlear hair cells associated ototoxicity by inducing apoptosis and oxidative stress, which can be alleviated by baicalin, one flavonoid extracted from the root of Scutellaria baicalensis." | 3.91 | Baicalin attenuates gentamicin-induced cochlear hair cell ototoxicity. ( Yu, J; Zhang, X, 2019) |
| "It is known that ototoxicity is the main cause of toxicity induced by aminoglycoside antibiotics." | 1.72 | Salicylate attenuates gentamicin-induced ototoxicity and facilitates the recovery in the basilar papilla of the lizard Podarcis siculus. ( Avallone, B; Fogliano, C; Motta, CM, 2022) |
| " In the present study, we compared the in vivo toxic effects of three aminoglycosides, gentamicin, amikacin, and etimicin, in zebrafish embryos." | 1.62 | A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos. ( Chen, D; Han, Y; Jiang, H; Jing, L; Li, R; Qian, X; Shao, W; Yin, Y; Zhong, D, 2021) |
| "Calcium dobesilate is a pharmacologically active agent used to treat many disorders due to its vasoprotective and antioxidant effects." | 1.56 | Does Calcium Dobesilate Have Therapeutic Effect on Gentamicin-induced Cochlear Nerve Ototoxicity? An Experimental Study. ( Altunay, ZÖ; Ataş, A; Çınar, Z; Edizer, DT; Gül, M; Yiğit, Ö, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 24 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niu, P | 1 |
| Sun, Y | 1 |
| Wang, S | 1 |
| Li, G | 1 |
| Tang, X | 1 |
| Sun, J | 2 |
| Pan, C | 1 |
| Yu, Y | 1 |
| Cao, L | 1 |
| Guan, N | 1 |
| Tang, Y | 1 |
| Han, M | 1 |
| Lin, JN | 3 |
| Wang, JS | 1 |
| Lin, CC | 2 |
| Lin, HY | 2 |
| Yu, SH | 2 |
| Wen, YH | 3 |
| Tseng, GF | 3 |
| Hsu, CJ | 3 |
| Wu, HP | 3 |
| Hwang, CF | 1 |
| Kmietowicz, Z | 1 |
| Abd-Elhakim, YM | 1 |
| Abdel-Motal, SM | 1 |
| Malhat, SM | 1 |
| Mostafa, HI | 1 |
| Ibrahim, WM | 1 |
| Beheiry, RR | 1 |
| Moselhy, AAA | 1 |
| Said, EN | 1 |
| Chatterton, S | 1 |
| Wang, C | 1 |
| Satyan, H | 1 |
| Kotsiou, G | 1 |
| Todd, CJ | 1 |
| Migliaccio, AA | 1 |
| Cremer, PD | 1 |
| Fogliano, C | 1 |
| Motta, CM | 1 |
| Avallone, B | 1 |
| Tuna, B | 2 |
| Tüzemen, G | 2 |
| Hong, MK | 1 |
| Echanique, KA | 1 |
| Hoffman, LF | 1 |
| Kita, AE | 1 |
| Chow, MR | 1 |
| Fernandez Brillet, C | 1 |
| Hageman, KN | 1 |
| Roberts, DC | 1 |
| Ayiotis, AI | 1 |
| Haque, RM | 1 |
| Della Santina, CC | 1 |
| Kalmanson, OA | 1 |
| McLoughlin, KC | 1 |
| Kiser, TH | 1 |
| Gubbels, SP | 1 |
| Low, WK | 1 |
| Teng, SW | 1 |
| Tan, MGK | 1 |
| Ding, D | 1 |
| Zhang, J | 1 |
| Jiang, H | 2 |
| Xuan, W | 1 |
| Qi, W | 1 |
| Salvi, R | 1 |
| Jiang, F | 1 |
| Kuper, H | 1 |
| Bright, T | 1 |
| Qin, WZ | 1 |
| Lai, R | 1 |
| Cai, C | 1 |
| Wu, W | 1 |
| Hu, P | 1 |
| Wang, Q | 1 |
| Wu, RS | 1 |
| Idkaidek, N | 1 |
| Hamadi, S | 1 |
| Bani-Domi, R | 1 |
| Al-Adham, I | 1 |
| Alsmadi, M | 1 |
| Awaysheh, F | 1 |
| Aqrabawi, H | 1 |
| Al-Ghazawi, A | 1 |
| Rabayah, A | 1 |
| Çınar, Z | 1 |
| Edizer, DT | 1 |
| Yiğit, Ö | 1 |
| Altunay, ZÖ | 1 |
| Gül, M | 1 |
| Ataş, A | 1 |
| Shao, W | 1 |
| Zhong, D | 1 |
| Han, Y | 1 |
| Yin, Y | 1 |
| Li, R | 1 |
| Qian, X | 1 |
| Chen, D | 1 |
| Jing, L | 1 |
| Semedo, MG | 1 |
| Dias-Silva, N | 1 |
| Miguéis, J | 1 |
| Pita, JR | 1 |
| Gao, D | 1 |
| Wu, H | 1 |
| Jie, H | 1 |
| Liang, M | 1 |
| Yu, D | 1 |
| Feng, Y | 1 |
| Balasubramanian, K | 1 |
| Zheng, G | 1 |
| Yang, J | 1 |
| He, J | 1 |
| Kenyon, EJ | 1 |
| Kirkwood, NK | 1 |
| Kitcher, SR | 1 |
| Goodyear, RJ | 1 |
| Derudas, M | 1 |
| Cantillon, DM | 1 |
| Baxendale, S | 1 |
| de la Vega de León, A | 1 |
| Mahieu, VN | 1 |
| Osgood, RT | 1 |
| Wilson, CD | 1 |
| Bull, JC | 1 |
| Waddell, SJ | 1 |
| Whitfield, TT | 1 |
| Ward, SE | 1 |
| Kros, CJ | 1 |
| Richardson, GP | 1 |
| Giurdanella, G | 1 |
| Montalbano, G | 1 |
| Gennuso, F | 1 |
| Brancati, S | 1 |
| Lo Furno, D | 1 |
| Augello, A | 1 |
| Bucolo, C | 1 |
| Drago, F | 1 |
| Salomone, S | 1 |
| Korkmaz, S | 1 |
| Ceylan, ME | 1 |
| Ceylan, G | 1 |
| Dalgıç, A | 1 |
| İnan, S | 1 |
| Olgun, L | 1 |
| Özüer, MZ | 1 |
| Kucharava, K | 1 |
| Sekulic-Jablanovic, M | 1 |
| Horvath, L | 1 |
| Bodmer, D | 1 |
| Petkovic, V | 1 |
| Ishikawa, M | 1 |
| García-Mateo, N | 1 |
| Čusak, A | 1 |
| López-Hernández, I | 1 |
| Fernández-Martínez, M | 1 |
| Müller, M | 1 |
| Rüttiger, L | 1 |
| Singer, W | 1 |
| Löwenheim, H | 1 |
| Kosec, G | 1 |
| Fujs, Š | 1 |
| Martínez-Martínez, L | 1 |
| Schimmang, T | 1 |
| Petković, H | 1 |
| Knipper, M | 1 |
| Durán-Alonso, MB | 1 |
| Zhang, X | 1 |
| Yu, J | 1 |
| Werner, M | 1 |
| Van De Water, TR | 1 |
| Stenlund, H | 1 |
| Berggren, D | 1 |
| Smyth, D | 1 |
| Mossman, S | 1 |
| Weatherall, M | 1 |
| Jolliffe, E | 1 |
| Joshi, P | 1 |
| Taylor, J | 1 |
| Thorne, K | 1 |
| Watson, E | 1 |
| Leadbetter, R | 1 |
| Mossman, B | 1 |
| Moss, T | 1 |
| Todd, N | 1 |
| Schneider, E | 1 |
1 trial available for gentamicin and Drug-Induced Cochlear Toxicity
| Article | Year |
|---|---|
Acupuncture Attenuates Ototoxicity Induced by Gentamicin in Mice.
Topics: Acupuncture Therapy; Animals; Cochlea; Gentamicins; Hair Cells, Auditory; Male; Mice; Ototoxicity | 2022 |
29 other studies available for gentamicin and Drug-Induced Cochlear Toxicity
| Article | Year |
|---|---|
Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line; Cell Survival; Gentamicins; Ha | 2021 |
Ameliorative effect of taxifolin on gentamicin-induced ototoxicity via down-regulation of apoptotic pathways in mouse cochlear UB/OC-2 cells.
Topics: Animals; Apoptosis; Down-Regulation; Gentamicins; Mice; Ototoxicity; Quercetin; Reactive Oxygen Spec | 2022 |
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Gentamicins; Glucosides; Mice; Ototoxicity; Stilb | 2022 |
Neonatal units in Manchester roll out genetic test for gentamicin ototoxicity.
Topics: Gentamicins; Humans; Infant, Newborn; Ototoxicity | 2022 |
Curcumin attenuates gentamicin and sodium salicylate ototoxic effects by modulating the nuclear factor-kappaB and apoptotic pathways in rats.
Topics: Animals; Apoptosis; Caspase 3; Curcumin; Gentamicins; NF-kappa B; Ototoxicity; Rats; Sodium Salicyla | 2022 |
A Prospective Study on the Vestibular Toxicity of Gentamicin in a Clinical Setting.
Topics: Aminoglycosides; Gentamicins; Head Impulse Test; Humans; Ototoxicity; Prospective Studies; Reflex, V | 2022 |
Salicylate attenuates gentamicin-induced ototoxicity and facilitates the recovery in the basilar papilla of the lizard Podarcis siculus.
Topics: Animals; Anti-Bacterial Agents; Bromodeoxyuridine; Gentamicins; Lizards; Mammals; Organ of Corti; Ot | 2022 |
Protective effects of nigella sativa oil against gentamicin-induced ototoxicity in rats: A dose-ranging study.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Male; Ototoxicity; Plant Oils; Rats; Rats, Sprague-Dawl | 2023 |
Protective effects of nigella sativa oil against gentamicin-induced ototoxicity in rats: A dose-ranging study.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Male; Ototoxicity; Plant Oils; Rats; Rats, Sprague-Dawl | 2023 |
Protective effects of nigella sativa oil against gentamicin-induced ototoxicity in rats: A dose-ranging study.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Male; Ototoxicity; Plant Oils; Rats; Rats, Sprague-Dawl | 2023 |
Protective effects of nigella sativa oil against gentamicin-induced ototoxicity in rats: A dose-ranging study.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Male; Ototoxicity; Plant Oils; Rats; Rats, Sprague-Dawl | 2023 |
Designing a Prolonged Method of Therapeutic Delivery to Support Rehabilitation From Ototoxic Damage in a Schwann Cell Model.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cisplatin; Gentamicins; Ototoxicity; Rats; Schwann C | 2023 |
Binocular 3-D otolith-ocular reflexes: responses of chinchillas to natural and prosthetic stimulation after ototoxic injury and vestibular implantation.
Topics: Animals; Chinchilla; Gentamicins; Otolithic Membrane; Ototoxicity; Reflex, Vestibulo-Ocular; Vestibu | 2023 |
Debilitating Gentamicin Ototoxicity: Case Report and Recommendations Against Routine Use in Surgical Prophylaxis.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Humans; Hypersensitivity; Ototoxicity; Penicillins | 2023 |
Synergistic Ototoxicity of Gentamicin and Low-Dose Irradiation: Molecular Basis and Clinical Significance.
Topics: Animals; Apoptosis; Cell Line; Cochlea; Gentamicins; Mice; Ototoxicity; Phosphorylation; Radiotherap | 2020 |
Some Ototoxic Drugs Destroy Cochlear Support Cells Before Damaging Sensory Hair Cells.
Topics: Animals; Apoptosis; Cadmium; Caspases; Cisplatin; Cochlea; Extracellular Matrix; Gentamicins; Hair C | 2020 |
Etiology of Childhood Bilateral Sensorineural Hearing Loss in Shandong Province, China.
Topics: Adolescent; Anti-Bacterial Agents; Asphyxia Neonatorum; Audiometry; Child; Child, Preschool; China; | 2020 |
Exosomes derived from mouse inner ear stem cells attenuate gentamicin-induced ototoxicity in vitro through the miR-182-5p/FOXO3 axis.
Topics: Animals; Ear, Inner; Exosomes; Forkhead Box Protein O3; Gentamicins; Mice; MicroRNAs; Ototoxicity; S | 2020 |
Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Survival; Fallopia multiflora; Ge | 2020 |
Saliva versus Plasma Therapeutic Drug Monitoring of Gentamicin in Jordanian Preterm Infants. Development of a Physiologically-Based Pharmacokinetic (PBPK) Model and Validation of Class II Drugs of Salivary Excretion Classification System.
Topics: Bacterial Infections; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug D | 2020 |
Does Calcium Dobesilate Have Therapeutic Effect on Gentamicin-induced Cochlear Nerve Ototoxicity? An Experimental Study.
Topics: Animals; Calcium Dobesilate; Cochlear Nerve; Evoked Potentials, Auditory, Brain Stem; Gentamicins; O | 2020 |
A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Embryo, Nonmammalian; Gentamicins; Gram-Negative Ba | 2021 |
Quinine in Otology and Neurotology: Ototoxicity and Historic Role in Therapy.
Topics: Gentamicins; Humans; Neurotology; Otolaryngology; Ototoxicity; Quinine | 2021 |
XIAP inhibits gentamicin-induced hair cell damage and ototoxicity through the caspase-3/9 pathway.
Topics: Animals; Caspase 3; Caspase 9; Dose-Response Relationship, Drug; Gentamicins; Hair Cells, Auditory; | 2021 |
Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.
Topics: Aminoglycosides; Animals; Cochlea; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Female; Genta | 2021 |
Isolation, cultivation, and characterization of primary bovine cochlear pericytes: A new in vitro model of stria vascularis.
Topics: Actins; Animals; Antigens; Biomarkers; Cattle; Cell Culture Techniques; Cell Survival; Cisplatin; Co | 2019 |
Auditory and Histopathological Effects of Topical Mercurochrome Treatment in Rats with Tympanic Membrane Perforation.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cochlea; Female; Gentamicins; Hearing; Merb | 2019 |
Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K-Akt pathway.
Topics: Animals; Anti-Bacterial Agents; Female; Gentamicins; Hair Cells, Auditory; Hearing Loss; Hormones; H | 2019 |
Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cell Line; Drug Resistance, | 2019 |
Baicalin attenuates gentamicin-induced cochlear hair cell ototoxicity.
Topics: Anti-Bacterial Agents; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Dose-Response Relations | 2019 |
Ultrastructural Characterization of Stem Cell-Derived Replacement Vestibular Hair Cells Within Ototoxin-Damaged Rat Utricle Explants.
Topics: Animals; Cell Transdifferentiation; Gentamicins; Hair Cells, Vestibular; Ototoxicity; Rats; Rats, Wi | 2020 |
Gentamicin vestibulotoxicity with modern systemic dosing regimens: a prospective study using video-oculography.
Topics: Adult; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Genta | 2019 |