2-methyl-1,3,4-thiadiazole-5-thiol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-methyl-1,3,4-thiadiazole-5-thiol: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	1810203
SCHEMBL ID	349852
MeSH ID	M0140923

Synonyms (54)

Synonym
AC-13309
5-methyl-3h-1,3,4-thiadiazole-2-thione
1,3,4-thiadiazole-2(3h)-thione, 5-methyl-
d2-1,3,4-thiadiazoline-5-thione, 2-methyl-
2-mercapto-5-methyl-1,3,4-thiadiazole
29490-19-5
inchi=1/c3h4n2s2/c1-2-4-5-3(6)7-2/h1h3,(h,5,6
5-methyl-1,3,4-thiadiazole-2-thiol, 99%
5-methyl-1,3,4-thiadiazole-2-thiol
STK177285
AKOS003677653
M0976
AKOS000120548
A819935
2-methyl-1,3,4-thiadiazole-5-thiol
c3h4n2s2
5-methyl-1,3,4-thiadiazole-2(3h)-thione
unii-9jy8uf0tss
ai3-62194
9jy8uf0tss ,
einecs 249-667-1
PS-6247
F9995-0046
AM90361
FT-0620541
SCHEMBL349852
5-methyl-1, 3,4-thiadiazole-2-thiol
5-methyl-1,3,4-thiadiazol-2-thiol
5-methyl-2-mercapto,1,3,4-thiadiazole
5-methyl-[1,3,4]thiadiazole-2-thiol
5-mercapto-2-methyl-1,3,4-thiadiazole
2-methyl-5-thioxo-1,3,4-thiadiazoline
2-mercapto-5-methyl -1,3,4-thiadiazole
5-methyl-[1,3,4]thiadiazol-2-thiol
2-methyl-5-mercapto-1,3,4-thiadiazole
2-methyl-1,3,4-thiadiazoline-5-thione
5-methyl-1,3,4-thiadiazol-2-yl hydrosulfide #
W-106986
mfcd00038349
DTXSID90183694
cefazolin sodium imp. e (ep); cefazolin imp. e (ep); 5-methyl-1,3,4-thiadiazol-2-thiol; mmtd; cefazolin sodium impurity e; cefazolin impurity e
5-methyl-1,3,4-thiadiazol-2-thiol (mmtd)
5-methyl-2,3-dihydro-1,3,4-thiadiazole-2-thione
5-methyl-1,3,4-thiadiazole-2-thione
CS-W013406
BCP21885
5-methyl-1,3,4-thiadiazole-2-thiol;1,3,4-thiadiazole-2(3h)-thione, 5-methyl-
EN300-20981
D70885
cefazolin sodium impurity e [ep impurity]
methylthiadiazole thiol
5-methyl-1,3,4-thiadiazolyl-2-thiol
Z104485716
PD148020

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	2 (40.00)	18.7374
1990's	1 (20.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.21

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	23.21 (24.57)
Research Supply Index	1.95 (2.92)
Research Growth Index	4.42 (4.65)
Search Engine Demand Index	18.60 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (23.21)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
mercury Mercury: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.. mercury(0) : Elemental mercury of oxidation state zero.	2.07	1	elemental mercury; zinc group element atom	neurotoxin
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	2.07	1	copper group element atom; elemental silver	Escherichia coli metabolite
glutamic acid Glutamic Acid: A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.. glutamic acid : An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.	2.37	2	glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical
cefazolin Cefazolin: A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.. cefazolin : A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively.	2.68	3	beta-lactam antibiotic allergen; cephalosporin; tetrazoles; thiadiazoles	antibacterial drug
moxalactam Moxalactam: Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.. moxalactam : A broad-spectrum oxacephem antibiotic in which the oxazine ring is substituted with a tetrazolylthiomethyl group and the azetidinone ring carries methoxy and 2-carboxy-2-(4-hydroxyphenyl)acetamido substituents.	1.96	1	cephalosporin; oxacephem	antibacterial drug
cephalosporin c cephalosporin C: RN given refers to parent cpd; structure in Merck, 9th ed, #1937. cephalosporin C : A cephalosporin antibiotic carrying a 3-acetoxymethyl substituent and a 6-oxo-N(6)-L-lysino group at position 7.	2.38	2	cephalosporin	fungal metabolite
7-aminocephalosporanic acid 7beta-aminocephalosporanic acid : The alpha,beta-unsaturated monocarboxylic acid that is the active nucleus for the synthesis of cephalosporins and intermediates.	1.99	1	alpha,beta-unsaturated monocarboxylic acid; amino acid zwitterion
2,5-dimercapto-1,3,4-thiadiazole dimercaptothiadiazole: structure in first source	2.07	1
1-n-methyl-5-thiotetrazole 1-N-methyl-5-thiotetrazole: side chain of several new antibiotics associated with development of hypoprothrombinemia	1.96	1
cefotaxime Cefotaxime: Semisynthetic broad-spectrum cephalosporin.. cefotaxime : A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.	1.96	1	1,3-thiazoles; cephalosporin; oxime O-ether	antibacterial drug; drug allergen

Condition	Relationship Strength	Studies
Deficiency, Factor II [description not available]	2.67	3
Deficiency, Vitamin K [description not available]	1.96	1
Vitamin K Deficiency A nutritional condition produced by a deficiency of VITAMIN K in the diet, characterized by an increased tendency to hemorrhage (HEMORRHAGIC DISORDERS). Such bleeding episodes may be particularly severe in newborn infants. (From Cecil Textbook of Medicine, 19th ed, p1182)	1.96	1

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