Hirschsprung Disease

Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.

Synonym
Hirschsprung Disease

Excerpt	Reference
"Hirschsprung disease is a heterogeneous genetic disorder, causative genes of which include the endothelin B receptor (ETB)."	( Ishii, K; Koshimizu, TA; Osawa, M; Saeki, M; Tanoue, A; Tsuchiya, M; Tsujimoto, G, 2002)
"Hirschsprung disease is a serious disorder of enteric nervous system (ENS) development caused by the failure of ENS precursor migration into the distal bowel."	( Fu, M; Heuckeroth, RO; Kane, MA; Lyons-Warren, A; Napoli, JL; Sato, Y; Zhang, B, 2010)
"Hirschsprung disease is a common cause of neonatal and infantile large gut obstruction."	( Das, K; Mohanty, S, 2017)

Excerpt	Reference
"A part of familial Hirschsprung disease has genetic factors in common with cerebrovascular disease."	( Abe, K; Hishikawa, N; Ohta, Y; Sasaki, R; Sato, K; Takemoto, M; Yamashita, T, 2019)

Excerpt	Reference
"The diagnosis and treatment of Hirschsprung disease are well standardized."	( Atayurt, H; Cetinkurşun, S; Demirbağ, S; Tiryaki, T, 2005)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	116 (24.84)	23.3326
1990's	114 (24.41)	12.5806
2000's	91 (19.49)	18.1394
2010's	110 (23.55)	28.8240
2020's	36 (7.71)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
4-hydroxyphenylacetic acid	low	1	0
quinacrine	low	1	0
bromide	low	1	0
carbon monoxide	low	2	0
chlorine	low	2	0
hydrogen sulfide	low	1	0
methylmalonic acid	low	1	0
cytosine	low	1	0
glycerol	low	1	0
glyoxylic acid	low	1	0
histamine	low	3	0
hydrogen	low	1	0
iodine	low	2	0
niacinamide	low	1	0
nitrous oxide	low	2	0
propionic acid	low	1	0
thiamine	low	1	0
oxyquinoline	low	1	0
aspirin	low	1	0
bisacodyl	low	1	0
bupivacaine	low	1	0
cilostazol	low	1	0
cisapride	medium	2	1
citalopram	low	1	0
dapi	low	1	0
diazoxide	low	1	0
valproic acid	low	2	0
thiorphan	low	1	0
fluconazole	low	1	0
gentamicin	low	1	0
guaifenesin	low	3	0
guanethidine	low	1	0
hydrochlorothiazide	low	1	0
lidocaine	low	1	0
indomethacin	low	1	0
iohexol	low	4	0
iopromide	low	1	0
ioxaglate	low	1	0
1-methyl-3-isobutylxanthine	low	3	0
2-propanol	low	8	0
isoproterenol	low	1	0
ketamine	low	1	0
loperamide	low	2	0
edaravone	low	1	0
metronidazole	low	3	0
midazolam	low	1	0
apnea	low	5	0
nifedipine	low	1	0
oxotremorine	low	2	0
oxybenzone	low	3	0
pargyline	low	1	0
phenoxybenzamine	low	1	0
propranolol	low	4	0
sevoflurane	low	2	0
sulfasalazine	low	1	0
tetraethylammonium	low	1	0
trimethobenzamide	low	1	0
corticosterone	low	1	0
prednisolone	low	2	0
phentolamine	low	4	0
thyroxine	low	3	0
carbachol	low	6	0
penicillamine	low	1	0
prednisone	low	1	0
dimethylphenylpiperazinium iodide	low	2	0
isoflurophate	low	1	0
alanine	low	1	0
serine	low	1	0
lysine	low	1	0
physostigmine	low	1	0
tubocurarine	low	2	0
bromodeoxyuridine	low	2	0
edetic acid	low	1	0
tyrosine	low	4	0
methacholine chloride	low	3	0
lactose	low	1	0
phenylalanine	low	1	0
colchicine	low	1	0
cytidine	low	1	0
arginine	low	5	0
isosorbide dinitrate	low	2	0
quinuclidines	low	1	0
diatrizoate meglumine	low	3	0
3-o-methylglucose	low	1	0
thiamine pyrophosphate	low	1	0
evans blue	low	2	0
citrulline	medium	1	1
hematoxylin	low	10	0
eosine yellowish-(ys)	low	7	0
glycopyrrolate	low	1	0
erythromycin	low	1	0
ethylnitrosourea	low	1	0
3,3',4',5-tetrachlorosalicylanilide	low	1	0
carmine	low	1	0
vancomycin	low	3	0
amiloride	low	1	0
metanephrine	low	1	0
enbucrilate	low	1	0
technetium	low	1	0
titanium	low	1	0
phosphoric acid, trisodium salt	low	2	0
barium sulfate	medium	58	1
silver nitrate	low	1	0
chlorine	low	1	0
barium chloride	low	1	0
trolamine salicylate	low	1	0
cromolyn sodium	medium	1	1
cresyl violet	low	1	0
iodine	low	1	0
phosphotyrosine	low	1	0
4-methoxyamphetamine	low	1	0
glutamic acid	low	1	0
torpedo	low	1	0
gallium citrate	low	1	0
substance p	low	14	0
ng-nitroarginine methyl ester	low	1	0
sufentanil	low	1	0
enkephalin, methionine	low	8	0
colforsin	low	1	0
fomesafen	low	34	0
adenosine	low	1	0
acridine orange	low	1	0
thomsen-friedenreich antigen	low	1	0
iopamidol	low	1	0
octadecyl palmitate	low	1	0
nicotine	low	2	0
fibrinogen	low	1	0
cobalt	low	1	0
racecadotril	low	1	0
mosapride	low	1	0
enkephalin-met, arg(6)-gly(7)-leu(8)-	low	1	0
antibiotic g 418	low	1	0
methotrexate	low	1	0
atropine	low	11	0
ropivacaine	medium	1	1
povidone-iodine	low	1	0
glucosamine	low	2	0
elastin	low	1	0
nitroarginine	low	5	0
rocuronium	low	1	0
tretinoin	low	2	0
retinol	low	2	0
mycophenolic acid	low	1	0
enkephalin, leucine	low	2	0
glycosides	low	1	0
isomethyleugenol	low	2	0
capsaicin	low	1	0
D-fructopyranose	low	1	0
nadp	low	1	0
rubeanic acid	low	2	0
zinc oxide	low	8	0
pica	low	1	0
cobaltous chloride	low	1	0
bilirubin	low	4	0
dinoprostone	low	2	0
dinoprost	low	1	0
echinacoside	low	1	0
menatetrenone	low	1	0
menaquinone 6	low	1	0
granisetron	low	1	0
naloxone	low	1	0
sirolimus	low	2	0
morphine	low	38	0
iloprost	low	1	0
barium	low	3	0
aluminum	low	1	0
gallium	low	1	0
cysteine	low	11	0
silicon	low	1	0
pepstatin	low	1	0
4-(4-diethylaminostyryl)-n-methylpyridinium	low	1	0
tetrodotoxin	low	10	0
selenium	low	1	0
s-nitroso-n-acetylpenicillamine	low	1	0
butylscopolammonium bromide	low	1	0
sincalide	low	1	0
pentagastrin	low	1	0
lipid a	low	1	0
td-5108	low	1	0
s-tetradecanoyl-coenzyme a	low	1	0
enerbol	low	2	0
acid phosphatase	low	1	0
jaw	low	1	0
ceruletide	low	1	0
glucagon	low	3	0
neuropeptide y	low	6	0
peptide phi	low	1	0
s6c sarafotoxin	low	1	0
oligonucleotides	low	2	0
endothelin-1	low	6	0
calpain	low	1	0
sodium pertechnetate tc 99m	low	1	0
neurotensin	low	2	0
mannans	low	1	0
piperidines	low	4	0
interleukin-8	medium	1	1
vasoactive intestinal peptide	low	29	0
epidermal growth factor	low	1	0
gastrin-releasing peptide	low	2	0
transforming growth factor beta	low	2	0
vitamin b 12	low	2	0
peptide yy	low	2	0
technetium tc 99m medronate	low	1	0
exudates	medium	2	1
cyclic gmp	low	1	0
guanosine monophosphate	low	1	0
olanzapine	low	1	0
eye	low	3	0
ego	low	1	0

Protein Targets (1,833)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, Phosphodiesterase 9A	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
Chain A, Class I phosphodiesterase PDEB1	0	1	0	1
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera	0	1	0	1
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
glp-1 receptor, partial	7	0	0	7
thyroid stimulating hormone receptor	22	0	0	22
estrogen-related nuclear receptor alpha	40	0	0	40
Phosphodiesterase	0	2	0	2
mitogen-activated protein kinase 1	16	0	0	16
geminin	44	0	0	44
cytochrome P450 3A4 isoform 1	19	0	0	19
histone acetyltransferase KAT2A isoform 1	15	0	0	15
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	19	4	1	24
Monocarboxylate transporter 4	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
Renin	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	19	4	1	24
Gamma-aminobutyric acid receptor subunit delta	19	4	1	24
Gamma-aminobutyric acid receptor subunit gamma-2	19	4	2	25
Gamma-aminobutyric acid receptor subunit alpha-5	19	4	1	24
Gamma-aminobutyric acid receptor subunit alpha-3	19	4	1	24
Gamma-aminobutyric acid receptor subunit gamma-1	19	5	1	25
Gamma-aminobutyric acid receptor subunit alpha-2	19	4	1	24
Adenosine receptor A1	0	6	1	10
Gamma-aminobutyric acid receptor subunit alpha-4	19	4	1	24
Gamma-aminobutyric acid receptor subunit gamma-3	19	4	1	24
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	4	3	9
Adenosine receptor A2b	0	0	1	3
Adenosine receptor A2b	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-6	19	4	1	24
Adenosine receptor A1	0	5	3	11
Adenosine receptor A2a	0	6	2	11
Sodium-dependent serotonin transporter	0	6	0	6
Adenosine receptor A2a	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	19	5	2	26
Gamma-aminobutyric acid receptor subunit beta-3	19	4	1	24
Gamma-aminobutyric acid receptor subunit beta-2	19	4	2	25
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	8
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Phosphodiesterase	0	1	0	1
GABA theta subunit	19	4	1	24
Phosphodiesterase	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	19	4	1	24
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
RAR-related orphan receptor gamma	35	0	0	35
GLI family zinc finger 3	35	0	0	35
AR protein	45	0	0	45
aldehyde dehydrogenase 1 family, member A1	32	0	0	32
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
retinoid X nuclear receptor alpha	33	0	0	33
estrogen nuclear receptor alpha	58	0	0	58
peroxisome proliferator-activated receptor delta	22	0	0	22
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	23	0	0	23
activating transcription factor 6	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	18	0	0	18
Histone H2A.x	14	0	0	14
thyroid hormone receptor beta isoform a	18	0	0	18
heat shock protein beta-1	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	37	0	0	37
lamin isoform A-delta10	38	0	0	38
Voltage-dependent calcium channel gamma-2 subunit	23	0	0	23
Glutamate receptor 2	24	3	1	30
Luciferase	20	0	0	20
acetylcholinesterase	16	0	0	16
SMAD family member 2	11	0	0	11
SMAD family member 3	11	0	0	11
estrogen receptor 2 (ER beta)	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	30	0	0	30
progesterone receptor	22	0	0	22
glucocorticoid receptor [Homo sapiens]	40	0	0	40
farnesoid X nuclear receptor	19	0	0	19
pregnane X nuclear receptor	29	0	0	29
peroxisome proliferator activated receptor gamma	21	0	0	21
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
aryl hydrocarbon receptor	20	0	0	20
thyrotropin-releasing hormone receptor	5	0	0	5
thyroid hormone receptor beta isoform 2	29	0	0	29
histone deacetylase 9 isoform 3	4	0	0	4
Cellular tumor antigen p53	28	0	0	28
Sporulation initiation phosphotransferase F	0	1	0	1
Sporulation kinase A	0	1	0	1
Prostaglandin G/H synthase 1	0	7	0	7
Thromboxane-A synthase	0	4	0	4
Mitogen-activated protein kinase 1	0	3	1	4
Prostaglandin G/H synthase 2	0	9	1	10
Mitogen-activated protein kinase 14	0	1	1	2
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE	0	1	0	1
Chain A, Protocatechuate 3,4-dioxygenase	0	1	0	1
Chain M, Protocatechuate 3,4-dioxygenase	0	1	0	1
Olfactory receptor class A-like protein 1	0	0	1	1
Smad3	8	0	0	8
DNA polymerase iota isoform a (long)	18	0	0	18
Carbonic anhydrase 1	0	14	0	20
Carbonic anhydrase 2	0	15	1	23
Carbonic anhydrase 5A, mitochondrial	0	4	0	8
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	0	8
5-hydroxytryptamine receptor 2C	0	5	1	7
5-hydroxytryptamine receptor 2A	0	7	2	9
5-hydroxytryptamine receptor 1A	0	8	2	11
5-hydroxytryptamine receptor 1B	0	5	1	6
5-hydroxytryptamine receptor 1D	0	3	1	4
5-hydroxytryptamine receptor 1F	0	3	1	4
5-hydroxytryptamine receptor 2B	0	4	1	5
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	12	2	14
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	3	1	4
5-hydroxytryptamine receptor 4	0	0	2	3
5-hydroxytryptamine receptor 3B	0	3	1	4
Telomerase reverse transcriptase	0	1	0	1
Amyloid-beta precursor protein	1	5	0	6
Reverse transcriptase/RNaseH	0	1	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	30	0	0	30
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
regulator of G-protein signaling 4	17	0	0	17
NPYLR7B	0	0	3	3
arylsulfatase A	18	0	0	18
IDH1	17	0	0	17
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
flap endonuclease 1	13	0	0	13
nuclear receptor ROR-gamma isoform 1	15	0	0	15
peripheral myelin protein 22	26	0	0	26
survival motor neuron protein isoform d	23	0	0	23
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	9	0	0	9
Purine nucleoside phosphorylase	0	2	0	2
Epidermal growth factor receptor	0	4	1	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Insulin receptor	0	0	1	2
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	0	1	2
Adenosine receptor A3	0	7	3	11
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	2
Inosine-5'-monophosphate dehydrogenase 2	0	3	1	4
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	3	0	3
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	1	2
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	1	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	14	0	0	14
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	1	0	3
Glutamate receptor ionotropic, NMDA 1	0	5	2	10
Proton-coupled amino acid transporter 1	0	3	0	3
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	3	4	7
Androgen receptor	0	5	0	5
Mineralocorticoid receptor	0	1	1	2
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Guanine nucleotide-binding protein G	6	0	0	6
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	32	0	0	32
TDP1 protein	45	0	0	45
glucocerebrosidase	8	0	0	8
alpha-galactosidase	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	46	0	0	46
Bloom syndrome protein isoform 1	14	0	0	14
cytochrome P450 2D6 isoform 1	9	0	0	9
lysosomal alpha-glucosidase preproprotein	4	0	0	4
cytochrome P450 2C19 precursor	7	0	0	7
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
huntingtin isoform 2	4	0	0	4
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	13	0	20
Bile salt export pump	0	48	0	48
Prothrombin	0	1	1	2
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	1	0	1
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	5
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Trypsin-3	0	1	0	1
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	7	0	8
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	18	0	18
Sodium channel protein type 5 subunit alpha	0	6	0	6
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	7	0	9
Solute carrier family 22 member 2	0	7	0	9
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
50S ribosomal protein L36 2	0	2	1	3
ATAD5 protein, partial	19	0	0	19
Microtubule-associated protein tau	23	0	0	23
D(1A) dopamine receptor	11	0	0	11
neuropeptide S receptor isoform A	5	0	0	5
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	18	0	0	18
NFKB1 protein, partial	5	0	0	5
GLS protein	19	0	0	19
chromobox protein homolog 1	25	0	0	25
muscarinic acetylcholine receptor M1	10	0	0	10
lethal factor (plasmid)	11	0	0	11
Cytochrome P450 3A4	0	12	3	16
Nitric oxide synthase, endothelial	0	3	0	5
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, brain	0	3	0	5
Nitric oxide synthase, inducible	0	4	0	5
Nitric oxide synthase, inducible	0	3	1	7
Cationic amino acid transporter 3	0	2	0	2
ATP-dependent phosphofructokinase	21	0	0	21
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	11	0	0	11
hypothetical protein, conserved	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	22	0	0	22
EWS/FLI fusion protein	18	0	0	18
cytochrome P450 2D6	17	0	0	17
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
DNA polymerase kappa isoform 1	13	0	0	13
Prostaglandin-H2 D-isomerase	0	2	0	2
ATP-binding cassette sub-family C member 3	0	27	0	27
Multidrug resistance-associated protein 4	0	27	0	30
Solute carrier family 22 member 6	0	4	0	4
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	3	1	1	5
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	3	1	1	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	15	1	1	17
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Canalicular multispecific organic anion transporter 1	0	26	0	26
Sigma non-opioid intracellular receptor 1	0	14	1	15
Sigma non-opioid intracellular receptor 1	0	2	1	3
cystic fibrosis transmembrane conductance regulator	0	2	0	2
DNA polymerase beta	4	0	0	4
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	16	2	18
Muscarinic acetylcholine receptor M2	0	12	6	23
Muscarinic acetylcholine receptor M4	0	11	5	20
Muscarinic acetylcholine receptor M1	0	11	2	17
Muscarinic acetylcholine receptor M3	0	11	2	16
Muscarinic acetylcholine receptor M4	0	12	1	16
Muscarinic acetylcholine receptor M5	0	11	1	15
Muscarinic acetylcholine receptor M5	0	10	5	19
Muscarinic acetylcholine receptor M2	0	12	1	17
Muscarinic acetylcholine receptor M1	0	11	7	23
Muscarinic acetylcholine receptor M1	0	1	2	4
Muscarinic acetylcholine receptor M3	0	12	6	22
Alpha-1D adrenergic receptor	0	12	3	16
5-hydroxytryptamine receptor 2C	0	17	1	18
Muscarinic acetylcholine receptor M4	0	2	0	2
Histamine H2 receptor	11	0	2	15
Muscarinic acetylcholine receptor	0	4	1	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
Chain A, Cruzipain	6	0	0	6
USP1 protein, partial	20	0	0	20
vitamin D3 receptor isoform VDRA	18	0	0	18
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	2	0	0	2
Inositol monophosphatase 1	8	0	0	8
Solute carrier organic anion transporter family member 1B3	0	6	0	9
Solute carrier organic anion transporter family member 1B1	0	7	0	9
Mcl-1	0	2	0	2
thioredoxin glutathione reductase	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
G	17	0	0	17
thyroid stimulating hormone receptor	16	0	0	16
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	6	0	0	6
cytochrome P450 2C9 precursor	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	11	0	0	11
G-protein coupled receptor 35 isoform a	0	1	0	1
G-protein coupled receptor 55	0	1	0	1
Interferon beta	20	0	0	20
HLA class I histocompatibility antigen, B alpha chain	17	0	0	17
Cytochrome P450 2C9	0	12	1	13
Aryl hydrocarbon receptor	0	0	1	1
Kappa-type opioid receptor	0	10	5	17
Spike glycoprotein	21	0	1	22
Sodium-dependent dopamine transporter	0	3	0	3
Inositol hexakisphosphate kinase 1	17	0	0	17
cytochrome P450 2C9, partial	17	0	0	17
Carbonic anhydrase 4	0	7	0	10
Carbonic anhydrase	0	4	0	7
Carbonic anhydrase 15	0	4	0	7
pregnane X receptor	11	0	0	11
bromodomain adjacent to zinc finger domain 2B	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
cellular tumor antigen p53 isoform a	6	0	0	6
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	18	0	0	18
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	2	3
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Beta-lactamase	12	0	0	12
15-lipoxygenase, partial	6	0	0	6
67.9K protein	11	0	0	11
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cytochrome P450 1A2	0	5	1	6
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Acetylcholinesterase	0	8	1	10
Cannabinoid receptor 2	0	1	0	1
D(2) dopamine receptor	0	5	2	7
Potassium voltage-gated channel subfamily A member 1	0	3	0	3
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
GALC protein	5	0	0	5
Neuronal acetylcholine receptor subunit alpha-3	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-4	0	5	2	8
Neuronal acetylcholine receptor subunit alpha-2	0	4	2	7
Neuronal acetylcholine receptor subunit beta-2	0	5	2	8
Neuronal acetylcholine receptor subunit beta-3	0	4	2	7
Neuronal acetylcholine receptor subunit beta-4	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-5	0	4	2	7
Delta-type opioid receptor	0	8	2	14
Neuronal acetylcholine receptor subunit alpha-6	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-9	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-7	0	4	2	7
Sigma non-opioid intracellular receptor 1	0	4	1	5
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	4	2	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
luciferase	2	0	0	2
eyes absent homolog 2 isoform a	2	0	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	5
Glutamate receptor 1	1	3	1	7
Glutamate receptor 3	1	3	1	7
Glutamate receptor 4	1	3	1	7
Tyrosine-protein phosphatase 1	0	2	0	2
Alpha-synuclein	4	3	0	7
C-terminal-binding protein 1	2	0	0	2
endonuclease IV	4	0	0	4
Thrombopoietin	7	0	0	7
peripheral myelin protein 22 isoform 1	7	0	0	7
M-phase phosphoprotein 8	10	0	0	10
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
5-hydroxytryptamine receptor 3E	0	3	0	3
5-hydroxytryptamine receptor 3B	0	3	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Beta-2 adrenergic receptor	0	7	3	11
Beta-1 adrenergic receptor	0	5	2	7
5-hydroxytryptamine receptor 1A	0	4	1	5
Alpha-2A adrenergic receptor	0	12	4	18
Cytochrome P450 2D6	0	6	1	7
Angiotensin-converting enzyme	0	9	0	9
Beta-3 adrenergic receptor	0	4	2	6
D(2) dopamine receptor	0	7	1	8
Dipeptidyl peptidase 4	0	1	0	1
Insulin receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	14	3	17
Alpha-2B adrenergic receptor	0	10	2	14
Alpha-2C adrenergic receptor	0	9	3	14
D	0	4	0	4
Alpha-2B adrenergic receptor	0	8	3	11
D(1A) dopamine receptor	0	5	1	6
Alpha-2C adrenergic receptor	0	8	3	11
Alpha-2A adrenergic receptor	0	8	3	11
Alpha-1D adrenergic receptor	0	11	3	15
Sodium-dependent dopamine transporter	0	3	0	3
5-hydroxytryptamine receptor 2A	0	11	1	12
Gastrin/cholecystokinin type B receptor	0	2	2	4
5-hydroxytryptamine receptor 7	0	4	1	5
Alpha-1A adrenergic receptor	0	5	4	10
Alpha-1B adrenergic receptor	0	4	3	8
D(3) dopamine receptor	0	9	0	9
5-hydroxytryptamine receptor 2B	0	17	1	18
Alpha-1A adrenergic receptor	0	14	3	17
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	2	4
Neutral alpha-glucosidase AB	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	7	0	7
5-hydroxytryptamine receptor 3D	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 3C	0	3	0	3
Heparanase	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
Aldo-keto reductase family 1 member B1	0	5	0	5
Tryptophan 5-hydroxylase 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Aromatase	0	1	0	1
Sodium-dependent noradrenaline transporter	0	5	0	5
Histamine H1 receptor	0	7	3	10
Sigma intracellular receptor 2	0	2	0	2
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	6	1	8
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	2
General amino-acid permease GAP1	0	0	0	1
Chain A, Ferritin light chain	6	0	0	6
PAX8	0	0	0	1
Fumarate hydratase	4	0	0	4
PPM1D protein	4	0	0	4
polyprotein	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	2	0	2
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
ras-related protein Rab-9A	5	0	0	5
steroidogenic factor 1	0	2	0	2
muscleblind-like protein 1 isoform 1	5	0	0	5
Solute carrier family 22 member 3	0	6	0	7
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	14	2	19
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	1	2
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Solute carrier family 2, facilitated glucose transporter member 1	0	1	1	2
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Adenylate cyclase type 1	0	1	1	2
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
nonstructural protein 1	6	0	0	6
Solute carrier family 22 member 2	0	4	0	8
Solute carrier family 22 member 3	0	1	0	2
C-8 sterol isomerase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Multidrug resistance-associated protein 5	0	0	0	1
Glucose transporter	0	1	0	1
Cdk-related protein kinase 6	0	1	0	1
Protein kinase domain-containing protein	0	1	0	1
Hexose transporter 1	0	1	0	1
Deoxycytidine kinase	0	0	1	2
Cytidine deaminase	0	0	0	1
Calcium-dependent protein kinase 1	0	1	0	1
Mitogen-activated protein kinase	0	1	0	1
Proline--tRNA ligase	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
Lysine--tRNA ligase	0	1	0	1
Uridine-cytidine kinase 1	0	0	0	1
Deoxycytidine kinase	0	0	0	1
Prothrombin	0	1	0	1
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
Hsf1 protein	0	0	4	4
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
Coagulation factor VII	0	2	0	2
Tissue factor	0	3	0	3
Nicotinamide phosphoribosyltransferase	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	1	2
ATP-sensitive inward rectifier potassium channel 11	0	1	1	2
isocitrate dehydrogenase 1, partial	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	2	0	3
DNA dC->dU-editing enzyme APOBEC-3A isoform a	0	1	0	1
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	3	3	6
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	4	2	6
Prostaglandin E2 receptor EP2 subtype	0	3	2	5
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	5	2	7
Solute carrier organic anion transporter family member 2A1	0	1	0	4
Prostaglandin D2 receptor	0	1	1	2
Solute carrier family 22 member 6	0	2	0	5
Solute carrier family 22 member 7	0	0	0	4
Solute carrier family 22 member 8	0	2	0	5
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	3
Solute carrier family 22 member 7	0	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
UDP-glucuronosyltransferase 1A9	0	0	0	4
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	4
UDP-glucuronosyltransferase 1-6	0	1	0	3
UDP-glucuronosyltransferase 1A1	0	2	0	4
UDP-glucuronosyltransferase 1A7	0	0	0	2
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Angiotensin-converting enzyme	0	2	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Endothelin-1 receptor	0	2	1	3
Opioid receptor, delta 1b	0	2	0	2
Opioid receptor homologue	0	2	0	2
Proenkephalin-B	0	0	1	1
Delta-type opioid receptor	0	10	3	14
Kappa-type opioid receptor	0	4	1	7
Mu-type opioid receptor	0	11	4	19
Kappa-type opioid receptor	0	6	3	10
Mu-type opioid receptor	0	9	5	16
Delta-type opioid receptor	0	8	6	16
Kappa-type opioid receptor	0	5	1	6
Mu-type opioid receptor	0	4	1	8
Mu-type opioid receptor	0	8	2	10
Mu-type opioid receptor	0	2	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	4	0	0	4
streptokinase A precursor	0	0	1	1
Motilin receptor	0	1	1	2
Albumin	0	3	5	8
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 2J2	0	7	0	7
10 kDa heat shock protein, mitochondrial	0	4	0	4
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Lanosterol 14-alpha demethylase	0	3	1	4
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Multidrug and toxin extrusion protein 1	0	4	0	4
Luciferin 4-monooxygenase	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	0	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	4	0	0	4
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	3	0	0	3
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	4	0	4
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	4	0	4
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
TAR DNA-binding protein 43	8	0	0	8
Histone deacetylase 1	0	4	0	4
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	4	1	5
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
hemoglobin subunit beta	1	0	0	1
Vpr	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Thymidylate synthase	0	3	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutathione reductase, mitochondrial	0	7	0	7
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	2	9
Glutamate receptor ionotropic, NMDA 2B	0	4	2	9
Glutamate receptor ionotropic, NMDA 2C	0	4	2	9
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	4	2	9
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	4	2	9
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	2	9
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
4-hydroxy-tetrahydrodipicolinate synthase	0	1	0	1
Chain A, Hypoxanthine Phosphoribosyltransferase	0	1	0	1
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE	0	1	0	1
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain A, Xanthine phosphoribosyltransferase	0	0	1	1
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Histidine triad nucleotide-binding protein 1	0	0	1	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	1	0	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
pyruvate kinase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
intestinal alkaline phosphatase precursor	0	0	1	1
DNA polymerase eta isoform 1	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Vif	0	1	0	1
Tat	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Pyruvate kinase PKM	0	1	1	2
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
phosphoglycerate kinase	1	0	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 12	0	2	0	5
Carbonic anhydrase 3	0	2	0	5
Macrophage migration inhibitory factor	0	2	0	2
Carbonic anhydrase 6	0	4	0	7
Histamine H2 receptor	0	5	2	7
Histamine H1 receptor	0	2	3	5
Histamine H1 receptor	0	2	1	3
Carbonic anhydrase 7	0	3	0	6
Carbonic anhydrase	0	0	0	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase 9	0	4	0	7
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	0	0	4
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	2
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 13	0	3	0	5
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	1	0	2
Carbonic anhydrase 14	0	2	0	5
Histamine H3 receptor	0	1	2	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Prostacyclin receptor	0	1	1	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Procathepsin L	0	2	1	3
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Caspase-1	0	1	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Aldo-keto reductase family 1 member C3	0	2	0	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Acetylcholinesterase	0	7	0	8
Acetylcholinesterase	0	1	1	2
Lysosomal protective protein	0	1	0	1
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
Beta-1 adrenergic receptor	0	1	2	5
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Bile salt export pump	0	9	0	9
Beta-2 adrenergic receptor	0	4	1	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Beta-1 adrenergic receptor	0	4	2	8
Beta-2 adrenergic receptor	0	0	1	1
D(4) dopamine receptor	0	4	0	4
Beta-adrenergic receptor kinase 1	0	0	2	2
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
D(1A) dopamine receptor	3	0	0	3
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	3	3	8
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	3
Cholinesterase	0	5	0	6
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	2	2
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Menin	0	1	0	1
Cocaine esterase	0	3	0	3
Transmembrane protease serine 2	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	2	1	3
Nociceptin receptor	0	1	0	1
Calmodulin	0	1	1	2
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Angiopoietin-1 receptor	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cruzipain	0	1	0	1
Vitamin K-dependent gamma-carboxylase	0	0	0	1
galanin receptor type 3	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
dopamine D1 receptor	2	0	0	2
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	2	2
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	2	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	2	2
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Protein-arginine deiminase type-4	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	1	5
tumor susceptibility gene 101 protein	2	0	0	2
Serine racemase	0	1	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Translocator protein	0	2	1	3
UDP-glucuronosyltransferase 1A4	0	1	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
Cytochrome P450 2C19	0	3	1	4
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
D(3) dopamine receptor	0	4	0	4
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Neurotensin receptor type 1	0	0	1	1
Neurotensin receptor type 2	0	1	1	3
Myelin basic protein	0	0	1	1
Neurotensin receptor type 1	0	1	1	2
Neurotensin receptor type 1	0	2	2	5
Neurotensin receptor type 2	0	2	1	3
Sortilin	0	1	0	1
Neutrophil elastase	0	1	0	1
Nitric oxide synthase, endothelial	0	3	0	3
Collagenase 3	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	3	1	4
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
tumor necrosis factor	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Phospholipase A2, membrane associated	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	1	2
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
D(4) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 6	0	4	1	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Transporter	0	1	0	1
MCOLN3 protein	0	0	1	1
transient receptor potential cation channel, subfamily N, member 1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
P53	1	0	0	1
Hormone-sensitive lipase	0	1	0	1
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Thermolysin	0	4	0	5
Cholinesterase	0	3	0	3
72 kDa type IV collagenase	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	2	1	3
Pyrroline-5-carboxylate reductase 1, mitochondrial	0	1	0	1
Renin	0	1	0	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Cholecystokinin receptor type A	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	3	3	6
Chain A, CATHEPSIN D	0	1	0	1
Chain B, CATHEPSIN D	0	1	0	1
Chain A, PLASMEPSIN II	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Pepsin A	0	2	0	2
Cathepsin D	0	2	0	3
Cathepsin B	0	1	0	1
Pro-cathepsin H	0	1	0	1
Candidapepsin-2	0	1	0	1
Pepsin A-5	0	1	0	1
Gag-Pro polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Cathepsin E	0	1	0	1
Plasmepsin-1	0	1	0	1
Plasmepsin-2	0	1	0	1
Cathepsin D	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 9	0	1	0	1
Plasmepsin 4	0	1	0	1
Protease	0	1	0	1
Cysteine protease	0	1	0	1
Chymotrypsin-C	0	1	0	1
Protease	0	2	0	2
D(1B) dopamine receptor	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	1	0	1
Nischarin	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	3
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Tyrosine-protein kinase Lck	0	0	1	2
Proto-oncogene tyrosine-protein kinase Src	0	0	1	2
Growth factor receptor-bound protein 2	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	4	2	11
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Free fatty acid receptor 2	0	0	1	1
Cytochrome P450 2C8	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	2	1	3
Cholecystokinin receptor type A	0	3	3	6
Vasopressin V1a receptor	0	1	1	2
Sodium/bile acid cotransporter	0	2	0	2
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
N	0	1	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Trypanothione reductase	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	3
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Tyrosine-protein kinase Fyn	0	0	1	1
Cyclin-dependent kinase 1	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	1	2
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	2	0	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Chain A, Glutathione S-transferase	0	1	0	1
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Flavin reductase (NADPH)	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 3	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Neprilysin	0	2	0	2
Neprilysin	0	2	0	2
Neprilysin	0	1	0	1
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Neprilysin	0	1	0	1
Endothelin-converting enzyme 1	0	2	0	2
Angiotensin-converting enzyme	0	1	0	1
Squalene synthase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	4	6
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (467)

Protein Targets (1,833)

Hirschsprung Disease

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (467)

Drugs Studied (246)

Protein Targets (1,833)