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cisapride and Hirschsprung Disease

cisapride has been researched along with Hirschsprung Disease in 2 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.

Research Excerpts

ExcerptRelevanceReference
"Cisapride is a potentially useful therapy in patients with pediatric short-bowel syndrome with gastrointestinal dysmotility."2.76Cisapride improves enteral tolerance in pediatric short-bowel syndrome with dysmotility. ( Duggan, C; Hart, K; Jaksic, T; Jiang, H; Kamin, DS; Nurko, S; Raphael, BP, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raphael, BP1
Nurko, S1
Jiang, H1
Hart, K1
Kamin, DS1
Jaksic, T1
Duggan, C1
Casasa, JM1

Trials

1 trial available for cisapride and Hirschsprung Disease

ArticleYear
Cisapride improves enteral tolerance in pediatric short-bowel syndrome with dysmotility.
    Journal of pediatric gastroenterology and nutrition, 2011, Volume: 52, Issue:5

    Topics: Child; Child, Preschool; Cisapride; Citrulline; Energy Intake; Enteral Nutrition; Enterocolitis, Nec

2011

Other Studies

1 other study available for cisapride and Hirschsprung Disease

ArticleYear
[The treatment of intestinal pseudo-obstruction].
    Anales espanoles de pediatria, 1991, Volume: 35 Suppl 47

    Topics: Cisapride; Colonic Diseases; Combined Modality Therapy; Hirschsprung Disease; Humans; Ileostomy; Inf

1991