thiorphan has been researched along with Hirschsprung Disease in 1 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grimaud, JC | 1 |
| Bouvier, M | 1 |
| Naudy, B | 1 |
| Salducci, J | 1 |
1 other study available for thiorphan and Hirschsprung Disease
| Article | Year |
|---|---|
Non-cholinergic neural excitation of the human rectum induced by acetorphan, an inhibitor of enkephalinase.
Topics: Adult; Analgesics; Electromyography; Enkephalins; Female; Hirschsprung Disease; Humans; Male; Nepril | 1989 |