phentolamine has been researched along with Hirschsprung Disease in 4 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
Excerpt | Relevance | Reference |
---|---|---|
" Excitatory junction potentials were accompanied by muscle contraction and abolished by atropine or tetrodotoxin." | 3.67 | Electrophysiological and pharmacological study on innervation of the aganglionic colon in Hirschsprung's disease of human and murine model. ( Okamoto, E; Okasora, T, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Matsufuji, H | 1 |
Okasora, T | 1 |
Okamoto, E | 1 |
Nirasawa, Y | 1 |
Yokoyama, J | 1 |
Ikawa, H | 1 |
Morikawa, Y | 1 |
Katsumata, K | 1 |
Wood, JD | 1 |
Brann, LR | 1 |
4 other studies available for phentolamine and Hirschsprung Disease
Article | Year |
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[Responses of muscle strips from the internal anal sphincter in Hirschsprung's disease to drugs and electrical field stimulation].
Topics: Anal Canal; Animals; Child, Preschool; Dogs; Electric Stimulation; Female; Hirschsprung Disease; Hum | 1990 |
Electrophysiological and pharmacological study on innervation of the aganglionic colon in Hirschsprung's disease of human and murine model.
Topics: Adolescent; Adult; Animals; Atropine; Child; Child, Preschool; Colon; Culture Techniques; Electric S | 1986 |
Hirschsprung's disease: catecholamine content, alpha-adrenoceptors, and the effect of electrical stimulation in aganglionic colon.
Topics: Atropine; Catecholamines; Chromatography, High Pressure Liquid; Colon; Dopamine; Electric Stimulatio | 1986 |
Pharmacological analysis of rebound excitation in large intestine of piebald mouse model for Hirschsprung's disease.
Topics: Animals; Atropine; Dimethylphenylpiperazinium Iodide; Guanethidine; Hirschsprung Disease; Indomethac | 1986 |