propranolol has been researched along with Hirschsprung Disease in 4 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Excitatory junction potentials were accompanied by muscle contraction and abolished by atropine or tetrodotoxin." | 3.67 | Electrophysiological and pharmacological study on innervation of the aganglionic colon in Hirschsprung's disease of human and murine model. ( Okamoto, E; Okasora, T, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomita, R | 1 |
| Morita, K | 1 |
| Tanjoh, K | 1 |
| Munakata, K | 1 |
| Okasora, T | 1 |
| Okamoto, E | 1 |
| Nirasawa, Y | 1 |
| Yokoyama, J | 1 |
| Ikawa, H | 1 |
| Morikawa, Y | 1 |
| Katsumata, K | 1 |
| Wood, JD | 1 |
| Brann, LR | 1 |
4 other studies available for propranolol and Hirschsprung Disease
| Article | Year |
|---|---|
A role of peptidergic nerves in the internal anal sphincter of Hirschsprung's disease.
Topics: Aged; Anal Canal; Atropine; Electric Stimulation; Female; Ganglia, Autonomic; Gastrointestinal Motil | 1999 |
Electrophysiological and pharmacological study on innervation of the aganglionic colon in Hirschsprung's disease of human and murine model.
Topics: Adolescent; Adult; Animals; Atropine; Child; Child, Preschool; Colon; Culture Techniques; Electric S | 1986 |
Hirschsprung's disease: catecholamine content, alpha-adrenoceptors, and the effect of electrical stimulation in aganglionic colon.
Topics: Atropine; Catecholamines; Chromatography, High Pressure Liquid; Colon; Dopamine; Electric Stimulatio | 1986 |
Pharmacological analysis of rebound excitation in large intestine of piebald mouse model for Hirschsprung's disease.
Topics: Animals; Atropine; Dimethylphenylpiperazinium Iodide; Guanethidine; Hirschsprung Disease; Indomethac | 1986 |