Page last updated: 2024-11-02

oxybenzone and Hirschsprung Disease

oxybenzone has been researched along with Hirschsprung Disease in 3 studies

oxybenzone : A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.

Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.

Research Excerpts

ExcerptRelevanceReference
"Oxybenzone is a ultraviolet (UV) absorber used in 70% of sunscreen products, is a recognized endocrine disrupting chemical (EDC) and is small enough to pass through skin and placenta barriers."2.61Can oxybenzone cause Hirschsprung's disease? ( DiNardo, JC; Downs, CA, 2019)
" What's more, we discovered dose-response relationship between RET expression and BP-3 exposure dose, and miR-218 and some other genes involved in SLIT2/ROBO1-miR-218-RET/PLAG1 pathway were also related to BP-3 exposure."1.43The relationship between prenatal exposure to BP-3 and Hirschsprung's disease. ( Cai, P; Chen, M; Huo, W; Li, H; Tang, J; Tang, W; Xia, Y; Xu, C; Zhu, D, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Wang, J1
Meng, X1
Feng, C1
Xiao, J1
Zhao, X1
Xiong, B1
Feng, J1
DiNardo, JC1
Downs, CA1
Huo, W1
Cai, P1
Chen, M1
Li, H1
Tang, J1
Xu, C1
Zhu, D1
Tang, W1
Xia, Y1

Reviews

1 review available for oxybenzone and Hirschsprung Disease

ArticleYear
Can oxybenzone cause Hirschsprung's disease?
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 86

    Topics: Benzophenones; Female; Hirschsprung Disease; Humans; Infant, Newborn; Maternal Exposure; Maternal-Fe

2019

Other Studies

2 other studies available for oxybenzone and Hirschsprung Disease

ArticleYear
Benzophenone-3 induced abnormal development of enteric nervous system in zebrafish through MAPK/ERK signaling pathway.
    Chemosphere, 2021, Volume: 280

    Topics: Animals; Benzophenones; Enteric Nervous System; Hirschsprung Disease; Proto-Oncogene Proteins c-ret;

2021
The relationship between prenatal exposure to BP-3 and Hirschsprung's disease.
    Chemosphere, 2016, Volume: 144

    Topics: Adult; Benzophenones; Case-Control Studies; Cell Culture Techniques; Cell Differentiation; Cell Move

2016