loperamide has been researched along with Hirschsprung Disease in 2 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Organic fecal incontinence is a consequence of congenital malformations affecting the anorectum, anal sphincters, or the spinal cord." | 2.41 | Fecal incontinence in anorectal malformations, neuropathy, and miscellaneous conditions. ( Rintala, RJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yap, FHX | 1 |
| Thom, G | 1 |
| Rintala, RJ | 1 |
1 review available for loperamide and Hirschsprung Disease
| Article | Year |
|---|---|
Fecal incontinence in anorectal malformations, neuropathy, and miscellaneous conditions.
Topics: Anal Canal; Antidiarrheals; Cecostomy; Child; Child, Preschool; Enema; Fecal Incontinence; Hirschspr | 2002 |
1 other study available for loperamide and Hirschsprung Disease
| Article | Year |
|---|---|
Perianal pseudoverrucous papules and nodules in Hirschsprung's disease: Rapid resolution with oral loperamide.
Topics: Antidiarrheals; Child, Preschool; Diaper Rash; Diarrhea; Giardiasis; Hirschsprung Disease; Humans; L | 2017 |