valproic acid has been researched along with Hirschsprung Disease in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hirschsprung Disease: Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal seizures were more frequent during drowsiness and sleep." | 1.39 | Epilepsy in Mowat-Wilson syndrome: delineation of the electroclinical phenotype. ( Bianchi, P; Bonetti, S; Boni, A; Buoni, S; Cecconi, I; Cerruti Mainardi, P; Cordelli, DM; Della Giustina, E; Doz, M; Epifanio, R; Faravelli, F; Ferrari, AR; Franzoni, E; Garavelli, L; Gelmini, C; Giordano, L; Grasso, M; Grioni, D; Grosso, S; Guerra, A; Licata, F; Malbora, B; Mammi, I; Mari, F; Mazzanti, L; Mostardini, R; Pantaleoni, C; Pellicciari, A; Poch-Olivé, ML; Rivieri, F; Rosato, S; Savasta, S; Seri, M; Simonte, G; Sorge, G; Tarani, L; Terazzi, E; Wischmeijer, A; Zanotta, N; Zollino, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ju, Y | 1 |
| Ji, TY | 1 |
| Cordelli, DM | 1 |
| Garavelli, L | 1 |
| Savasta, S | 1 |
| Guerra, A | 1 |
| Pellicciari, A | 1 |
| Giordano, L | 1 |
| Bonetti, S | 1 |
| Cecconi, I | 1 |
| Wischmeijer, A | 1 |
| Seri, M | 1 |
| Rosato, S | 1 |
| Gelmini, C | 1 |
| Della Giustina, E | 1 |
| Ferrari, AR | 1 |
| Zanotta, N | 1 |
| Epifanio, R | 1 |
| Grioni, D | 1 |
| Malbora, B | 1 |
| Mammi, I | 1 |
| Mari, F | 1 |
| Buoni, S | 1 |
| Mostardini, R | 1 |
| Grosso, S | 1 |
| Pantaleoni, C | 1 |
| Doz, M | 1 |
| Poch-Olivé, ML | 1 |
| Rivieri, F | 1 |
| Sorge, G | 1 |
| Simonte, G | 1 |
| Licata, F | 1 |
| Tarani, L | 1 |
| Terazzi, E | 1 |
| Mazzanti, L | 1 |
| Cerruti Mainardi, P | 1 |
| Boni, A | 1 |
| Faravelli, F | 1 |
| Grasso, M | 1 |
| Bianchi, P | 1 |
| Zollino, M | 1 |
| Franzoni, E | 1 |
2 other studies available for valproic acid and Hirschsprung Disease
| Article | Year |
|---|---|
[Clinical features of epilepsy in 5 children with Mowat-Wilson syndrome].
Topics: Child; Electroencephalography; Epilepsy; Facies; Female; Hirschsprung Disease; Humans; Intellectual | 2022 |
Epilepsy in Mowat-Wilson syndrome: delineation of the electroclinical phenotype.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; DNA Mutational Analysis; Electroencephalograph | 2013 |