Heat Stroke

A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.

Synonym
Heat Stroke

Excerpt	Reference
"Classic heat stroke is a disorder of thermal regulation that predominantly affects elderly patients during heat waves."	( Amaladevi, B; Funaro, R; Grob, D; Herzlich, BC; Koutelos, K; Pagala, M; Tan, W, 1995)
"6."	( Eichner, ER, 1998)
"Heat stroke is characterized by hyperthermia, arterial hypotension, decreased baroreflex sensitivity, and increased serum levels of beta-endorphin."	( Chen, JS; Huang, YP; Lin, MT; Wu, PY, 2005)
"Heat stroke is a life-threatening illness characterized by an increased core body temperature as a result of exposure to high ambient temperature."	( Corral, J; Galbis-Martinez, L; Hernández-Espinosa, D; Miñano, A; Mota, RA; Ordoñez, A; Parrilla, P; Vicente, V; Yélamos, J, 2008)
"Heat stroke is still an epidemiologically relevant disease with overall mortality rates as high as 15-33%."	( Lurie, KG; McKnite, S; Voelckel, WG; Yannopoulos, D; Zielinski, T, 2008)
"Nevertheless, as heat stroke is a severe inflammatory response disease, we hypothesized that AT III would inhibit inflammation and prevent heat stress-induced acute heat stroke."	( Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T; Shingu, C; Uchida, T, 2010)
"Heat stroke is a life-threatening illness that affects all segments of society with few effective treatment strategies to mitigate the long-term debilitating consequences of this syndrome."	( Helwig, BG; Leon, LR, 2010)
"Heat stroke is a condition characterized by high body temperature that can lead to hemorrhage and necrosis in multiple organs."	( Hagiwara, S; Iwasaka, H; Matsumoto, S; Mizunaga, S; Nishida, T; Noguchi, T; Saikawa, T; Shingu, C; Uchida, T, 2011)
"Heat stroke is a life-threatening illness characterized by an elevated core body temperature."	( Cheng, PY; Ding, C; Lam, KK; Lee, YM; Liu, WH; Liu, YP; Yen, MH, 2013)
"Heat stroke is the most severe pathology related to heat."	( Bejarano Ramírez, N; Latorre Latorre, JF; López-Menchero Oliva, C; Martínez Jiménez, MD; Pareja Grande, J; Rosich Del Cacho, M, 2014)
"Heat stroke is a medical emergency."	( Chang, CM; Chen, PJ; Lee, CP, 2015)
"Exertional heat stroke is defined as hyperthermia associated with neurological signs related to intense physical activity performed in a hot environment."	( Ben Mansour, A; Ferjani, M; Khoufi, MT; Lamine, K; Mrabet, A; Yedeas, M, 2016)
"Heat stroke is characterized by hyperthermia, systemic inflammation, and multiple organ failure including arterial hypotension."	( Lin, CH; Lin, MT; Lin, X; Liu, L; Ye, Z; Zhao, T; Zuo, D, 2017)
"Heat stroke is a lethal condition which can cause dysfunction in the central nervous system, multi-organ damage and even death."	( Huang, C; James, TD; Jia, N; Wang, Y; Wu, L, 2018)
"Heat stroke is a symptom of hyperthermia with a temperature of more than 40 °C, which usually leads to all kinds of physical discomfort and even death."	( Gao, GQ; Guo, XY; Liang, ZZ; Ma, QJ; Mao, GJ; Su, L; Wang, YY; Zhang, G; Zhang, H, 2019)
"Heat stroke is a life-threatening disease characterized by hyperthermia and neurological dysfunction."	( Han, S; Kim, BK; Yum, KS, 2020)
"Heat stroke is characterized by excessive oxidative stress and inflammatory responses, both of which are implicated in vascular endothelial glycocalyx shedding and heat-stroke mortality."	( Katoh, T; Kobayashi, K; Mimuro, S; Nakajima, Y; Sato, T; Truong, SK, 2021)
"Heat stroke is a life-threatening disorder triggered by thermoregulatory failure."	( Chen, MH; Chiu, YL; Fu, YH; Hii, HP; Ka, SM; Lo, WZ; Shih, CC; Tsao, CM; Wu, CC, 2022)
"Heat stroke is a problem that occurs primarily in the out-of-hospital environment."	( Abo, B; Beaver, B; Jacobsen, RC, 2023)
"Non-exertional heat stroke is defined as exposure to high outdoor temperatures, core body temperature >40 °C, and alteration of mentation."	( Everitt, B; Fine, B; Miramontes, D; Young, D, 2023)
"Exertional heat stroke is a life-threatening emergency necessitating immediate treatment with rapid body cooling."	( Fitts, T; Haboian, K; Pryor, RR; Stooks, JJ, 2023)

Excerpt	Reference
"All vehicle-pretreated heat stroke animals displayed systemic inflammation (evidenced by increased TNF-alpha, IL-1alpha, and IL-6) and activated coagulation (evidenced by increased levels of activated partial thromboplastin time, prothrombin time, and D-dimer and decreased levels of both platelet count and protein C)."	( He, DD; Li, YJ; Li, YL; Lin, MT; Lin, XJ; Liu, XQ; Mei, GP; Zhao, TB; Zou, F, 2009)
"YC-1 (20mg/kg) pretreatment with heat stroke (YC-1+HS) group, the MAP and heart rate were return to normal, and the biochemical markers were all significantly recovered to normal."	( Cheng, PY; Ding, C; Lam, KK; Lee, YM; Liu, WH; Liu, YP; Yen, MH, 2013)
"In the absence of LPS/LTA, heat treatment induced heat stroke and animal death without significant systemic or neuroinflammation."	( Gu, XL; He, X; Li, GB; Li, ZW; Shi, HW; Su, YN; Zhang, K; Zhang, YM; Zhang, ZT; Zhao, X; Zhu, JB, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	14 (4.28)	23.3326
1990's	43 (13.15)	12.5806
2000's	105 (32.11)	18.1394
2010's	107 (32.72)	28.8240
2020's	58 (17.74)	9.53

Drug	Relationship Strength	Studies	Trials
2,3-dihydroxybenzoic acid	low	5	0
gamma-aminobutyric acid	low	1	0
adenine	low	1	0
quinacrine	medium	2	1
cadaverine	low	1	0
carbon monoxide	low	1	0
carnitine	low	1	0
choline	low	1	0
chlorine	low	4	0
creatine	low	3	0
lactic acid	medium	13	3
formaldehyde	low	1	0
glycerol	low	10	0
carbonic acid	low	1	0
hydrogen	low	1	0
iodine	medium	2	1
dihydroxyphenylalanine	low	1	0
melatonin	low	4	0
nitrates	low	4	0
nitrites	low	5	0
pyruvic acid	low	9	0
sulfur dioxide	low	2	0
thiamine	low	1	0
uric acid	low	3	0
urea	low	2	0
n-methyl-3,4-methylenedioxyamphetamine	low	3	0
7-nitroindazole	low	1	0
pimagedine	low	2	0
dan 2163	low	1	0
amitriptyline	low	1	0
aristolochic acid i	low	1	0
aspirin	low	3	0
caffeine	low	4	0
chloral hydrate	low	1	0
chloroquine	low	1	0
chlorpromazine	low	2	0
dantrolene	low	15	0
amphetamine	low	3	0
diazepam	low	1	0
erythrosine	low	1	0
fenoldopam	low	1	0
fluoxetine	low	2	0
flutamide	low	1	0
gabapentin	low	1	0
haloperidol	low	1	0
halothane	low	4	0
ibuprofen	low	1	0
indomethacin	low	1	0
ketamine	low	1	0
ketanserin	low	1	0
kynurenic acid	low	1	0
metyrapone	low	1	0
midazolam	low	1	0
ml 7	low	1	0
monodansylcadaverine	low	1	0
ondansetron	low	1	0
oxybutynin	low	1	0
phenazopyridine	low	1	0
4-phenylbutyric acid	low	1	0
procaine	low	1	0
promethazine	low	1	0
propofol	low	2	0
sulpiride	low	1	0
trazodone	low	1	0
trihexyphenidyl	low	2	0
urethane	low	1	0
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	low	1	0
zonisamide	low	2	0
corticosterone	low	3	0
thyroxine	low	2	0
triiodothyronine	low	1	0
aspartic acid	low	3	0
glutamine	low	4	0
lysine	low	1	0
sucrose	low	1	0
edetic acid	low	1	0
mepazine	low	2	0
lactose	medium	1	1
mannitol	low	3	0
arginine	low	3	0
catechin	low	1	0
indazoles	low	2	0
isoxazoles	low	2	0
thiazoles	low	2	0
evans blue	low	1	0
hesperidin	low	1	0
methamphetamine	low	1	0
malondialdehyde	low	5	0
acetylcysteine	low	3	0
ethyl pyruvate	low	1	0
clopenthixol	low	2	0
d-alpha tocopherol	low	1	0
amiloride	low	1	0
titanium	low	3	0
gadolinium	low	1	0
gold	low	1	0
deuterium	low	1	0
ozone	low	5	0
rhamnose	medium	1	1
titanium dioxide	low	1	0
iodine	low	1	0
neohesperidin dihydrochalcone	low	1	0
bromocriptine	low	1	0
4-methoxyamphetamine	low	2	0
glutamic acid	low	14	0
5,7-dihydroxytryptamine	low	1	0
ng-nitroarginine methyl ester	low	2	0
fluorodopa f 18	low	1	0
ipsapirone	low	1	0
adenosine	low	1	0
acridine orange	low	1	0
glucose, (beta-d)-isomer	low	1	0
baicalin	low	1	0
n-acetylaspartic acid	low	1	0
glutathione disulfide	low	1	0
hesperetin	low	1	0
methotrimeprazine	low	1	0
cadusafos	low	1	0
fulvestrant	low	1	0
artesunic acid	low	1	0
deoxyglucose	low	1	0
peroxynitrous acid	low	2	0
angiotensin ii, des-phe(8)-	low	1	0
bq 610	low	1	0
l 368899	low	1	0
omega-n-methylarginine	low	1	0
hydroxyl radical	low	2	0
rhodioloside	low	1	0
angiotensin ii	low	2	0
cortisone	low	1	0
epiglucan	low	1	0
oxytocin	low	1	0
ryanodine	low	1	0
gingerol	low	1	0
bq 123	low	2	0
sodium arsenite	low	1	0
pectins	low	1	0
cocaine	low	2	0
eicosapentaenoic acid	low	1	0
l 743,872	low	1	0
shikonin	low	1	0
isomethyleugenol	low	1	0
sesquiterpenes	low	1	0
tetrahydropalmatine	low	1	0
curcumin	low	1	0
benztropine	low	1	0
D-fructopyranose	low	6	0
lithium	low	1	0
nitrogen dioxide	low	1	0
dermatan sulfate	low	1	0
mtt formazan	low	1	0
naphthoquinones	low	1	0
quercetin	low	3	0
bilirubin	low	4	0
dinoprostone	low	2	0
7,3'-dihydroxy-4'-methoxyisoflavone	low	1	0
alprostadil	low	1	0
3-methylquercetin	low	1	0
myricetin	low	1	0
geranylgeranylacetone	low	1	0
misoprostol	low	1	0
topiramate	low	6	0
17-(dimethylaminoethylamino)-17-demethoxygeldanamycin	low	1	0
dexmedetomidine	low	2	0
ag-490	low	1	0
naltrexone	low	3	0
dextromethorphan	low	1	0
carbocyanines	low	1	0
dizocilpine maleate	low	2	0
hydroxysafflor yellow a	low	1	0
clopenthixol decanoate	low	1	0
phosphocreatine	low	1	0
formazans	low	1	0
ave 0991	low	1	0
mocetinostat	low	4	0
1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride	low	1	0
losartan potassium	low	1	0
pituitrin	low	1	0
atrial natriuretic factor	low	3	0
beta-endorphin	medium	2	1
cellulose	low	1	0
endothelin-1	low	1	0
thimerosal	low	1	0
calpain	low	1	0
tanshinone ii a sodium sulfonate	low	1	0
quetiapine fumarate	low	1	0
triiodothyronine, reverse	low	1	0
piperidines	low	1	0
interleukin-8	low	1	0
natriuretic peptide, brain	low	3	0
heparitin sulfate	low	1	0
ascorbic acid	low	2	0
calca protein, human	low	4	0
transforming growth factor beta	low	2	0
platonin	low	2	0
lewis x antigen	low	1	0
angiotensin i	low	1	0
ginkgolide b	low	1	0
lactoferrin	medium	1	1
neohesperidin	low	1	0
thromboplastin	low	4	0
chondroitin sulfates	low	1	0
3-methyladenine	low	1	0
neopterin	low	1	0
clozapine	low	1	0
olanzapine	low	3	0
liproxstatin-1	low	1	0
lipoteichoic acid	low	1	0
phenanthrenes	low	2	0

Protein Targets (1,529)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Gamma-aminobutyric acid receptor subunit pi	23	9	4	36
Lysine-specific demethylase 6B	0	1	0	1
Lysine-specific demethylase 4B	0	1	0	1
Heat shock protein HSP 90-alpha	0	3	4	7
Heat shock protein HSP 90-beta	0	3	2	5
Cholesteryl ester transfer protein	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	23	9	4	36
Gamma-aminobutyric acid receptor subunit delta	23	9	4	36
Gamma-aminobutyric acid receptor subunit gamma-2	23	9	5	37
5-hydroxytryptamine receptor 1A	0	27	3	30
Gamma-aminobutyric acid receptor subunit alpha-5	23	9	4	36
Gamma-aminobutyric acid receptor subunit alpha-3	23	9	4	36
Gamma-aminobutyric acid receptor subunit gamma-1	23	9	4	36
Gamma-aminobutyric acid receptor subunit alpha-2	23	9	4	36
Gamma-aminobutyric acid receptor subunit alpha-4	23	9	4	36
Gamma-aminobutyric acid receptor subunit gamma-3	23	9	4	36
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	23	9	4	36
Endoplasmin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	23	10	5	38
Gamma-aminobutyric acid receptor subunit beta-3	23	9	4	36
Gamma-aminobutyric acid receptor subunit beta-2	23	9	5	37
Hypoxia-inducible factor 1-alpha	0	2	0	2
GABA theta subunit	23	9	4	36
Endothelial PAS domain-containing protein 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	23	9	4	36
Lysine-specific demethylase 4C	0	1	0	1
Chain A, Neutrophil gelatinase-associated lipocalin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
72 kDa type IV collagenase	0	2	0	2
Matrilysin	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Chain A, HADH2 protein	22	0	0	22
Chain B, HADH2 protein	22	0	0	22
Chain A, 2-oxoglutarate Oxygenase	17	0	0	17
Chain A, Ferritin light chain	10	0	0	10
endonuclease IV	6	0	0	6
glp-1 receptor, partial	8	0	0	8
thioredoxin reductase	37	0	0	37
15-lipoxygenase, partial	14	0	0	14
phosphopantetheinyl transferase	22	0	0	22
ATAD5 protein, partial	18	0	0	18
Fumarate hydratase	11	0	0	11
USP1 protein, partial	24	0	0	24
NFKB1 protein, partial	13	0	0	13
TDP1 protein	47	0	0	47
Microtubule-associated protein tau	23	0	0	23
thioredoxin glutathione reductase	8	0	0	8
Smad3	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	33	0	0	33
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	11	0	0	11
regulator of G-protein signaling 4	26	0	0	26
EWS/FLI fusion protein	20	0	0	21
nonstructural protein 1	7	0	0	7
estrogen-related nuclear receptor alpha	35	0	0	35
polyprotein	11	0	0	11
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
arylsulfatase A	20	0	0	20
euchromatic histone-lysine N-methyltransferase 2	56	0	0	56
Bloom syndrome protein isoform 1	20	0	0	20
cytochrome P450 2D6 isoform 1	17	0	0	17
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
peripheral myelin protein 22 isoform 1	12	0	0	12
cellular tumor antigen p53 isoform a	10	0	0	10
cytochrome P450 2C19 precursor	18	0	0	18
cytochrome P450 2C9 precursor	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	18	0	0	18
vitamin D3 receptor isoform VDRA	18	0	0	18
chromobox protein homolog 1	30	0	0	30
mitogen-activated protein kinase 1	19	0	0	19
atrial natriuretic peptide receptor 2 precursor	7	0	0	7
ras-related protein Rab-9A	10	0	0	10
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
DNA polymerase iota isoform a (long)	19	0	0	19
geminin	34	0	0	34
survival motor neuron protein isoform d	17	0	0	17
cytochrome P450 3A4 isoform 1	23	0	0	23
M-phase phosphoprotein 8	12	0	0	12
muscarinic acetylcholine receptor M1	22	0	0	22
lamin isoform A-delta10	37	0	0	37
Polyunsaturated fatty acid lipoxygenase ALOX15B	13	1	0	14
Guanylate cyclase soluble subunit beta-2	0	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Integrin beta-3	7	2	1	10
Integrin alpha-IIb	7	2	1	10
Guanylate cyclase soluble subunit alpha-2	0	0	0	1
Alpha-synuclein	4	4	1	9
Histamine H2 receptor	19	1	0	23
Guanylate cyclase soluble subunit alpha-1	0	0	0	1
Guanylate cyclase soluble subunit beta-1	0	0	0	1
Histone acetyltransferase p300	0	2	0	2
CREB-binding protein	0	2	0	2
Ataxin-2	21	0	0	21
ATP-dependent phosphofructokinase	26	0	0	26
Chain A, DNA-3-methyladenine glycosylase I	0	0	1	1
Chain A, DNA-3-METHYLADENINE GLYCOSYLASE I	0	0	1	1
Chain A, Dna-3-methyladenine Glycosylase I	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	29	0	0	29
flap endonuclease 1	19	0	0	19
DNA polymerase kappa isoform 1	24	0	0	24
Carbonic anhydrase 12	0	8	0	10
Pancreatic triacylglycerol lipase	0	3	0	3
Carbonic anhydrase 1	0	21	0	27
Carbonic anhydrase 2	0	22	3	31
Cytochrome P450 1A1	0	6	1	7
Cytochrome P450 1A2	0	7	1	8
Carbonic anhydrase 4	0	13	0	15
Carbonic anhydrase 7	0	9	0	11
Xanthine dehydrogenase/oxidase	0	6	0	6
Oligo-1,6-glucosidase IMA1	0	2	0	2
Mitogen-activated protein kinase 10	0	4	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Mitogen-activated protein kinase 14	0	5	0	5
Cytochrome P450 1B1	0	7	1	8
Inositol polyphosphate multikinase	0	3	0	3
Enoyl-acyl-carrier protein reductase	0	4	0	4
3-oxoacyl-acyl-carrier protein reductase	0	3	0	3
Aurora kinase B	0	4	0	4
Inositol hexakisphosphate kinase 2	0	3	0	3
5-hydroxytryptamine receptor 2C	0	18	3	21
5-hydroxytryptamine receptor 2A	0	20	3	23
5-hydroxytryptamine receptor 1B	0	19	2	21
5-hydroxytryptamine receptor 1D	0	8	2	10
5-hydroxytryptamine receptor 1F	0	8	2	10
5-hydroxytryptamine receptor 2B	0	18	4	22
5-hydroxytryptamine receptor 6	0	3	2	5
Sodium-dependent serotonin transporter	0	24	5	29
Sodium-dependent serotonin transporter	0	10	1	12
5-hydroxytryptamine receptor 7	0	7	2	9
5-hydroxytryptamine receptor 5A	0	3	2	5
5-hydroxytryptamine receptor 5B	0	3	2	5
5-hydroxytryptamine receptor 3A	0	5	3	8
5-hydroxytryptamine receptor 4	0	3	2	5
5-hydroxytryptamine receptor 3B	0	5	3	8
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Histone deacetylase 3	0	7	0	7
Histone deacetylase 4	0	6	0	6
Histone deacetylase 1	0	8	0	8
Histone deacetylase 7	0	6	0	6
Histone deacetylase 2	0	8	0	8
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	5	0	5
Histone deacetylase 8	0	7	0	7
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Histone deacetylase 6	0	6	0	6
Histone deacetylase 9	0	5	0	5
Histone deacetylase 5	0	6	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
nuclear receptor ROR-gamma isoform 1	15	0	0	15
muscleblind-like protein 1 isoform 1	7	0	0	7
neuropeptide S receptor isoform A	9	0	0	9
Aromatase	0	6	0	6
Amine oxidase [flavin-containing] A	0	1	0	1
Nitric oxide synthase, endothelial	0	3	0	5
Nitric oxide synthase, endothelial	0	5	0	6
Nitric oxide synthase, brain	0	7	0	9
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, inducible	0	6	0	7
Nitric oxide synthase, inducible	0	5	1	9
Nitric oxide synthase, endothelial	0	1	0	1
Luciferase	15	0	0	15
BRCA1	1	0	0	1
DNA polymerase beta	9	0	0	9
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	9	0	0	9
acetylcholinesterase	18	0	0	18
dopamine D1 receptor	6	0	0	6
pregnane X receptor	6	0	0	6
RAR-related orphan receptor gamma	30	0	0	30
Thrombopoietin	6	0	0	6
AR protein	42	0	0	42
glucocorticoid receptor [Homo sapiens]	33	0	0	33
retinoic acid nuclear receptor alpha variant 1	31	0	0	31
retinoid X nuclear receptor alpha	27	0	0	27
farnesoid X nuclear receptor	14	0	0	14
estrogen nuclear receptor alpha	51	0	0	51
vitamin D (1,25- dihydroxyvitamin D3) receptor	17	0	0	17
D(1A) dopamine receptor	20	0	0	20
thyroid hormone receptor beta isoform a	13	0	0	13
thyroid hormone receptor beta isoform 2	34	0	0	34
heat shock protein beta-1	11	0	0	11
peripheral myelin protein 22	20	0	0	20
Solute carrier family 22 member 6	0	4	0	4
Guanine nucleotide-binding protein G	3	0	0	3
Telomerase reverse transcriptase	0	1	0	1
Amyloid-beta precursor protein	0	8	0	9
Reverse transcriptase/RNaseH	0	1	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear receptor subfamily 1, group I, member 3	20	0	0	20
cytochrome P450 family 3 subfamily A polypeptide 4	35	0	0	35
pregnane X nuclear receptor	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
importin subunit beta-1 isoform 1	6	0	0	6
snurportin-1	6	0	0	6
tumor susceptibility gene 101 protein	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Bile salt export pump	0	45	0	45
Cyclin-dependent kinase 1	0	4	0	4
Glutamate receptor 2	19	3	1	24
TAR DNA-binding protein 43	9	0	0	9
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	10	0	0	10
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
NPYLR7B	0	0	3	3
IDH1	11	0	0	11
Histone H2A.x	15	0	0	15
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
high affinity choline transporter 1 isoform a	0	2	0	2
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	6	0	0	6
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	9	0	9
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	3	0	3
Insulin receptor	0	1	0	2
Phosphoglycerate kinase 2	0	1	0	1
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	4	2	7
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	11	1	13
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	4	3	9
Adenosine receptor A2b	0	1	1	4
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	5	3	11
Adenosine receptor A2a	0	8	1	11
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
WRN	2	0	0	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
GLS protein	31	0	0	31
apical membrane antigen 1, AMA1	6	0	0	6
glucocerebrosidase	13	0	0	13
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6	0	0	6
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
potassium voltage-gated channel subfamily H member 2 isoform d	17	0	0	17
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
histone-lysine N-methyltransferase 2A isoform 2 precursor	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	12	0	0	12
DNA polymerase eta isoform 1	6	0	0	6
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
lethal factor (plasmid)	18	0	0	18
pyruvate kinase PKM isoform b	1	0	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Tyrosine-protein kinase JAK1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	13	1	15
Tyrosine-protein kinase JAK3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	12	1	14
Glutamate receptor ionotropic, NMDA 2B	0	13	1	15
Glutamate receptor ionotropic, NMDA 2C	0	13	1	15
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
large T antigen	0	3	0	3
peroxisome proliferator activated receptor gamma	16	0	0	16
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	28
Cellular tumor antigen p53	34	0	0	34
Thromboxane-A synthase	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	3	0	3
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin E2 receptor EP1 subtype	0	3	0	3
Prostacyclin receptor	0	3	2	5
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Canalicular multispecific organic anion transporter 1	0	24	0	24
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
acid sphingomyelinase	1	0	0	1
thyroid stimulating hormone receptor	19	0	0	19
alpha-galactosidase	4	0	0	4
lysosomal alpha-glucosidase preproprotein	5	0	0	5
huntingtin isoform 2	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	29	0	0	29
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	12	0	15
Prothrombin	0	3	4	7
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	3	0	3
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	3	0	3
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	1
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	3	0	3
Trypsin-2	0	3	0	3
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	5	0	5
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Trypsin-3	0	3	0	3
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	7	0	7
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	20	0	20
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	5	0	6
Solute carrier family 22 member 2	0	5	0	6
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
cytochrome P450 2D6	21	0	0	21
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
5-hydroxytryptamine receptor 4	0	24	0	24
Albumin	0	0	8	8
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	25	0	25
Muscarinic acetylcholine receptor M2	0	21	2	24
Muscarinic acetylcholine receptor M4	0	22	1	23
Muscarinic acetylcholine receptor M1	0	11	0	11
Muscarinic acetylcholine receptor M3	0	9	0	9
Muscarinic acetylcholine receptor M4	0	7	0	7
Muscarinic acetylcholine receptor M5	0	7	0	7
Muscarinic acetylcholine receptor M5	0	25	0	25
Alpha-2A adrenergic receptor	0	28	1	29
Muscarinic acetylcholine receptor M2	0	11	0	11
Muscarinic acetylcholine receptor M1	0	24	2	27
Angiotensin-converting enzyme	0	10	0	10
D(2) dopamine receptor	0	23	3	33
Alpha-2B adrenergic receptor	0	26	1	27
Alpha-2C adrenergic receptor	0	23	1	24
Muscarinic acetylcholine receptor M3	0	24	1	25
D(1A) dopamine receptor	0	15	2	20
D(1B) dopamine receptor	0	5	0	8
UDP-glucuronosyltransferase 1A4	0	1	0	6
Sodium-dependent noradrenaline transporter	0	28	3	31
Histamine H2 receptor	0	14	0	14
Alpha-1D adrenergic receptor	0	25	0	25
5-hydroxytryptamine receptor 2A	0	29	2	35
5-hydroxytryptamine receptor 2C	0	26	2	29
Histamine H1 receptor	0	6	0	6
Histamine H1 receptor	0	19	3	24
D(3) dopamine receptor	0	28	2	37
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	4	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 2B	0	29	1	31
Alpha-1A adrenergic receptor	0	18	2	20
D(1A) dopamine receptor	8	1	0	9
5-hydroxytryptamine receptor 6	0	23	0	25
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Sodium-dependent dopamine transporter	0	15	2	17
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	6	2	8
Nuclear receptor subfamily 3 group C member 3	0	9	0	9
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	28	1	29
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	5	0	5
Sodium channel protein type 10 subunit alpha	0	3	0	3
Solute carrier family 22 member 3	0	3	0	3
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Sodium-dependent dopamine transporter	0	14	1	15
Beta-2 adrenergic receptor	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	7	1	8
histone acetyltransferase KAT2A isoform 1	13	0	0	13
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	2	3	5
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	1	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Cytochrome P450 3A4	0	13	2	18
Cationic amino acid transporter 3	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Cyclin-dependent kinase 2	0	3	0	3
Chain A, Hyaluronidase, phage associated	0	1	0	1
GLI family zinc finger 3	26	0	0	26
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
Polyphenol oxidase 2	0	3	0	4
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	1	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Spike glycoprotein	16	3	6	25
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	2
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	11	1	13
Glutamate receptor ionotropic, NMDA 3B	0	11	1	13
Carbonic anhydrase 4	0	3	0	4
Glutamate receptor ionotropic, NMDA 3A	0	11	1	13
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	5	0	0	5
hypothetical protein, conserved	5	0	0	5
peroxisome proliferator-activated receptor delta	18	0	0	18
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	5	0	6
Prostaglandin G/H synthase 2	0	3	0	4
Fatty acid-binding protein, liver	0	3	0	3
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	6	1	8
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	9	0	9
Substance-P receptor	0	6	0	6
Prostaglandin G/H synthase 2	0	9	1	10
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Nuclear receptor ROR-gamma	6	0	0	6
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Proto-oncogene Mas	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	7	0	7
Gamma-aminobutyric acid receptor subunit delta	0	7	0	7
Lysine-specific histone demethylase 1A	0	5	0	5
Replicase polyprotein 1ab	0	10	8	18
Replicase polyprotein 1ab	0	14	10	24
G2/mitotic-specific cyclin-B1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	9	5	14
Gamma-aminobutyric acid receptor subunit beta-1	0	8	2	10
Gamma-aminobutyric acid receptor subunit gamma-2	0	8	4	12
Dipeptidyl peptidase 4	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	9	3	12
Gamma-aminobutyric acid receptor subunit alpha-5	0	8	4	12
Gamma-aminobutyric acid receptor subunit alpha-3	0	8	3	11
5-hydroxytryptamine receptor 7	0	10	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	0	8	3	11
Gamma-aminobutyric acid receptor subunit beta-2	0	8	4	12
Prolyl endopeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	8	2	10
Serine/threonine-protein kinase PLK1	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	8	2	10
Canalicular multispecific organic anion transporter 1	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	7	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	0	7	0	7
Gamma-aminobutyric acid receptor subunit theta	0	7	0	7
Spike glycoprotein	0	3	6	9
Replicase polyprotein 1ab	0	4	6	10
Transmembrane protease serine 2	0	3	6	9
Procathepsin L	0	4	6	10
Replicase polyprotein 1a	0	3	6	9
Replicase polyprotein 1ab	0	3	6	9
Angiotensin-converting enzyme 2	0	4	6	10
Chain A, Cruzipain	10	0	0	10
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	3	0	0	4
Inositol monophosphatase 1	7	0	0	7
Solute carrier organic anion transporter family member 1B3	0	4	0	6
Solute carrier organic anion transporter family member 1B1	0	4	0	7
Solute carrier organic anion transporter family member 1A4	0	2	0	5
Multidrug resistance-associated protein 6	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Endothelin receptor type B	0	2	0	2
Endothelin-1 receptor	0	2	0	3
Endothelin-1 receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
Endothelin-1 receptor	0	1	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
Genome polyprotein	0	4	2	6
G	19	0	0	19
Interferon beta	22	0	0	22
HLA class I histocompatibility antigen, B alpha chain	19	0	0	19
ATP-dependent translocase ABCB1	0	2	0	2
ATP-dependent translocase ABCB1	0	8	2	15
Beta-1 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	12	6	18
Androgen receptor	0	5	0	5
D	0	13	1	15
D(3) dopamine receptor	0	10	0	10
Alpha-2B adrenergic receptor	0	12	1	13
ATP-dependent translocase ABCB1	0	2	0	2
Alpha-2C adrenergic receptor	0	12	1	13
Alpha-2A adrenergic receptor	0	13	1	14
D(1B) dopamine receptor	0	9	0	9
D(4) dopamine receptor	0	10	0	10
D(2) dopamine receptor	0	19	2	23
Inositol hexakisphosphate kinase 1	19	0	0	19
cytochrome P450 2C9, partial	19	0	0	19
Carbonic anhydrase 3	0	6	0	6
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase 6	0	9	0	11
Carbonic anhydrase 5A, mitochondrial	0	7	2	11
Carbonic anhydrase 9	0	8	1	12
Carbonic anhydrase 15	0	8	0	8
Carbonic anhydrase 13	0	4	0	6
Carbonic anhydrase 14	0	5	0	7
Carbonic anhydrase 5B, mitochondrial	0	7	0	9
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
thyroid stimulating hormone receptor	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	17	0	0	17
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Potassium channel subfamily K member 2	0	3	1	4
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	1	0	1
Cholinesterase	0	4	0	4
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Acetylcholinesterase	0	11	0	11
Amine oxidase [flavin-containing] B	0	8	0	8
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	0	3
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	1	2
Phosphodiesterase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	1	4
Guanine deaminase	0	2	0	2
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	6	0	6
Carbonic anhydrase	0	2	0	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Arginase	0	5	0	5
Sucrase-isomaltase, intestinal	0	1	0	1
Mu-type opioid receptor	0	6	3	13
Delta-type opioid receptor	0	4	2	10
Kappa-type opioid receptor	0	4	1	10
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Death-associated protein kinase 1	0	3	0	3
Beta-secretase 1	0	6	0	6
Carbonic anhydrase 3	0	3	0	3
Dihydroorotate dehydrogenase	0	2	0	2
PPM1D protein	3	0	0	3
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	5	5
Histidine-rich protein PFHRP-II	0	2	0	3
Spike glycoprotein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
DNA ligase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	3	0	3
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
caspase 7, apoptosis-related cysteine protease	9	0	0	9
estrogen receptor 2 (ER beta)	15	0	0	15
progesterone receptor	21	0	0	21
NADPH oxidase 1	0	1	0	1
67.9K protein	11	0	0	11
Snq2p	0	0	0	3
caspase-3	9	0	0	9
Adenylate cyclase type 1	0	4	0	4
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
histone deacetylase 9 isoform 3	4	0	0	4
Proteasome subunit alpha type-7	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	5	0	5
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	5	0	5
Bile salt export pump	0	5	0	5
Albumin	0	3	5	9
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Major prion protein	0	1	1	2
Tyrosine-protein kinase Fyn	0	1	0	1
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	6	1	7
Cytochrome P450 2D6	0	10	1	15
Cytochrome P450 2C9	0	10	0	11
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Alpha-1B adrenergic receptor	0	16	2	18
Sphingomyelin phosphodiesterase	0	1	0	1
D(2) dopamine receptor	0	8	0	8
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(4) dopamine receptor	0	12	1	18
Adenylate cyclase type 3	0	4	0	4
Alpha-1D adrenergic receptor	0	15	2	17
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	4	0	4
Adenylate cyclase type 4	0	4	0	4
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	3	0	4
Trypanothione reductase	0	6	0	6
Histamine H1 receptor	0	4	0	4
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
Adenylate cyclase type 8	0	4	0	4
Proteasome subunit beta type-10	0	0	0	1
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Cytochrome P450 2J2	0	7	0	8
Gastrin/cholecystokinin type B receptor	0	3	0	3
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	3	4
Aldehyde oxidase 1	0	2	0	2
Adenylate cyclase type 6	0	4	0	4
Adenylate cyclase type 5	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	6	0	6
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	6	0	6
Glutamate receptor ionotropic, NMDA 2B	0	6	0	6
Glutamate receptor ionotropic, NMDA 2C	0	5	0	5
Adenylyl cyclase 7	0	4	0	4
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	5	0	5
D	0	5	0	5
Proteasome subunit beta type-7	0	0	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	2	0	4
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	4	0	4
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
5-hydroxytryptamine receptor 3E	0	4	1	6
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
Beta-1 adrenergic receptor	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	2	0	0	2
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 3B	0	4	1	6
Beta-2 adrenergic receptor	0	5	0	5
Beta-1 adrenergic receptor	0	3	0	3
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	3	0	3
Beta-3 adrenergic receptor	0	3	0	3
Cytochrome P450 2C19	0	6	0	7
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-1A adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 3A	0	5	1	7
5-hydroxytryptamine receptor 5A	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	1	3
Transporter	0	4	0	4
Cholecystokinin receptor type A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
5-hydroxytryptamine receptor 3D	0	4	1	6
5-hydroxytryptamine receptor 3C	0	4	1	6
Histamine H4 receptor	0	1	1	2
Transporter	0	5	0	5
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Leukotriene B4 receptor 2	0	1	0	1
GALC protein	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
Solute carrier family 22 member 3	0	2	0	2
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	0	1	1
C-8 sterol isomerase	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Glucocorticoid receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Nrf2	3	0	0	3
SMAD family member 2	7	0	0	7
SMAD family member 3	7	0	0	7
alkaline phosphatase, intestinal	0	1	1	2
PINK1	1	0	0	1
Parkin	4	0	0	4
toll-like receptor 9	0	2	0	2
TPA: protein transporter TIM10	0	2	0	2
aryl hydrocarbon receptor	16	0	0	16
activating transcription factor 6	12	0	0	12
thyrotropin-releasing hormone receptor	3	0	0	3
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	2	0	2
hemoglobin subunit beta	2	0	0	2
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	2	0	2
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	4	0	0	4
pyruvate kinase PKM isoform a	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
hypothetical protein SA1422	0	1	0	1
Prostaglandin E synthase	0	2	0	2
Acetylcholinesterase	0	2	0	2
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	5	0	5
60 kDa chaperonin	0	2	0	2
Microtubule-associated protein tau	0	2	0	3
60 kDa heat shock protein, mitochondrial	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	2	0	2
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Heme oxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	2	0	2
Cholinesterase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Lactoylglutathione lyase	0	5	0	5
Serine/threonine-protein kinase PAK 1	0	1	0	1
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Thiosulfate sulfurtransferase	0	2	0	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	2	0	2
Alpha-tocopherol transfer protein	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Taste receptor type 2 member 46	0	0	1	1
Cytochrome P450 2D4	0	1	0	1
Gamma-aminobutyric acid	0	1	1	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	3
Translocator protein	0	3	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Glutamate receptor 1	2	3	1	7
Glutamate receptor 3	2	3	1	7
Glutamate receptor 4	2	3	1	7
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier family 22 member 6	0	2	0	4
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	3	0	4
Solute carrier family 22 member 7	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Oxoeicosanoid receptor 1	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
Luciferin 4-monooxygenase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	3
Nuclear factor NF-kappa-B p105 subunit	0	0	0	1
Tyrosine-protein phosphatase 1	0	2	0	2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	2	0	2
DNA polymerase III, partial	3	0	0	3
Lysine-specific demethylase 4E	0	2	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
Cytochrome P450 2C8	0	4	0	4
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Cocaine esterase	0	3	0	4
Androgen receptor	0	3	1	4
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Estrogen receptor	0	2	2	6
Estrogen receptor	0	1	0	1
Progesterone receptor	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	4	0	4
Beta-lactamase TEM	0	1	0	1
Estrogen receptor beta	0	2	0	2
Bile acid receptor	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	4	0	4
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Regulatory protein RhlR	0	1	0	2
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	6	0	6
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	3	1	5
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	3	1	5
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	3	0	4
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	3	0	3
Glutamate receptor ionotropic, kainate 4	0	3	0	4
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	3	0	4
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Glutathione reductase	0	0	0	1
Multidrug resistance-associated protein 1	0	4	0	5
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	3
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	2	0	2
Integrin alpha-4	0	2	0	2
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	4
Delta-type opioid receptor	0	7	1	8
Mu-type opioid receptor	0	9	1	10
Kappa-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	4	0	5
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	2	0	2
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
serine-protein kinase ATM isoform a	1	0	0	1
Carboxylic ester hydrolase	0	2	0	2
Neuraminidase	0	4	0	4
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Nischarin	0	1	0	1
Substance-K receptor	0	3	0	3
Heparanase	0	0	1	1
Acid-sensing ion channel 3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	5
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	1	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Mu-type opioid receptor	0	6	1	8
Prostaglandin G/H synthase 2	0	2	0	3
Prostaglandin G/H synthase 1	0	3	0	4
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	1	2
Cyclin-A2	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	2	0	2
Cyclin-A1	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Aldo-keto reductase family 1 member B1	0	3	0	3
Aldo-keto reductase family 1 member C4	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Alpha-2A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Synaptic vesicular amine transporter	0	2	0	2
Mitogen-activated protein kinase 13	0	1	0	1
Aryl hydrocarbon receptor	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Mitogen-activated protein kinase 11	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	4	3	7
Histamine H3 receptor	0	1	1	2
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Retinoic acid receptor RXR-alpha	0	0	1	1
Chain A, Peroxisome proliferator-activated receptor gamma	0	0	1	1
Vpr	1	0	0	1
Aldehyde dehydrogenase, mitochondrial	0	0	1	1
Cannabinoid receptor 1	0	1	1	2
Cannabinoid receptor 2	0	1	1	2
G-protein coupled bile acid receptor 1	0	1	0	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
ClpP	1	0	0	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] B	0	2	0	2
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	1	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Rho-associated protein kinase 1	0	1	0	1
Myosin light chain kinase, smooth muscle	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Pancreatic alpha-amylase	0	1	0	1
Chain A, Pancreatic alpha-amylase	0	1	0	1
RGS12	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
pyruvate kinase	1	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
serine/threonine-protein kinase PLK1	3	0	0	3
glycogen synthase kinase-3 alpha	0	0	0	1
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3A isoform a	0	1	0	1
Tyrosine-protein kinase transforming protein Fps	0	1	0	1
Protein E6	0	2	0	2
Interstitial collagenase	0	2	1	3
Alpha-amylase 1A	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 2	0	2	0	2
Serine/threonine-protein kinase pim-1	0	2	1	4
Pyruvate kinase PKM	0	1	1	2
Insulin-degrading enzyme	0	1	0	1
Serine/threonine-protein kinase B-raf	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 4	0	2	0	2
Casein kinase II subunit alpha'	0	3	0	3
DNA primase TraC	0	1	0	1
DNA-(apurinic or apyrimidinic site) endonuclease	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Cystathionine beta-synthase	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	2	0	2
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Tyrosine-protein kinase SYK	0	2	2	4
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	2	0	2
Anthrax toxin receptor 2	0	2	0	2
Casein kinase II subunit beta	0	3	0	3
Casein kinase II subunit alpha	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
2-5A-dependent ribonuclease	0	1	0	2
ELAV-like protein 3	0	2	0	2
Integrase	0	2	0	2
Casein kinase II subunit alpha 3	0	3	0	3
Aldo-keto reductase family 1 member C21	0	3	0	3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Short transient receptor potential channel 5	0	2	0	2
Sialidase-2	0	2	0	2
phosphoglycerate kinase	2	0	0	2
Histidine decarboxylase	0	0	1	1
Delta-type opioid receptor	0	5	1	7
Kappa-type opioid receptor	0	2	1	3
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A8	0	0	0	2
Neutrophil elastase	0	5	0	5
Collagenase 3	0	4	0	4
Sodium/iodide cotransporter	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	2
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Interleukin-6 receptor subunit alpha	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Thyrotropin-releasing hormone receptor	0	1	0	1
Glycine receptor subunit alpha-4	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Nischarin	0	1	0	1
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Vasopressin V2 receptor	0	2	1	3
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	2	1	3
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Complement C1s subcomponent	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	1	0	2
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
hexokinase	0	1	0	1
galactokinase	1	0	0	1
interferon gamma precursor	0	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Prothrombin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Stromelysin-1	0	1	0	1
Hepatocyte growth factor receptor	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Urease subunit alpha	0	3	0	3
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Urease subunit beta	0	3	0	3
Lactoperoxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	3
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
N	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Ribonuclease HI	0	1	0	1
Sterol O-acyltransferase 2	0	1	0	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
Pyruvate kinase PKLR	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
DNA topoisomerase 2-beta	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Neuraminidase	0	1	0	1
Class A sortase SrtA	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	3	0	3
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Delta carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
D(2) dopamine receptor	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
caspase recruitment domain family, member 15	0	1	0	1
neurotensin receptor type 1	0	0	1	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 13	0	3	0	3
Thyroid hormone receptor beta	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Carbonic anhydrase 2	0	1	0	1
Amine oxidase [flavin-containing]	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (327)

Protein Targets (1,529)

Heat Stroke

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (327)

Drugs Studied (241)

Protein Targets (1,529)