3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Heat Stroke in 1 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Heat Stroke: A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.
| Excerpt | Relevance | Reference |
|---|---|---|
| "YC-1 (20mg/kg) pretreatment with heat stroke (YC-1+HS) group, the MAP and heart rate were return to normal, and the biochemical markers were all significantly recovered to normal." | 1.39 | The role of heat shock protein 70 in the protective effect of YC-1 on heat stroke rats. ( Cheng, PY; Ding, C; Lam, KK; Lee, YM; Liu, WH; Liu, YP; Yen, MH, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lam, KK | 1 |
| Cheng, PY | 1 |
| Lee, YM | 1 |
| Liu, YP | 1 |
| Ding, C | 1 |
| Liu, WH | 1 |
| Yen, MH | 1 |
1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Heat Stroke
| Article | Year |
|---|---|
The role of heat shock protein 70 in the protective effect of YC-1 on heat stroke rats.
Topics: Animals; Arterial Pressure; Disease Models, Animal; DNA-Binding Proteins; Enzyme Activators; Gene Ex | 2013 |