hydroxysafflor-yellow-a and Heat-Stroke

hydroxysafflor-yellow-a has been researched along with Heat-Stroke* in 1 studies

Other Studies

1 other study(ies) available for hydroxysafflor-yellow-a and Heat-Stroke

ArticleYear
[Hydroxysafflor yellow A attenuates heat stroke-induced acute lung injury in mice by inhibiting necroptosis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2022, Dec-20, Volume: 42, Issue:12

    To investigate the protective effect of hydroxysafflor yellow A (HSYA) against heat stroke (HS)-induced acute lung injury and its possible mechanism.. HSYA pretreatment at the moderate and high doses significantly improved heat tolerance of the mice with comparable effects. At the optimal dose of 2.25 mg/kg, HSYA pretreatment significantly increased heat tolerance of the mice (. Severe HS results in necroptosis in the lung tissue of mice, which can be alleviated by HSYA pretreatment.

    Topics: Acute Lung Injury; Animals; Heat Stroke; HMGB1 Protein; Interleukin-6; Mice; Mice, Inbred C57BL; Necroptosis; Tumor Necrosis Factor-alpha

2022