quinacrine has been researched along with Heat Stroke in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Heat Stroke: A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study is to assess the prophylactic effect of quinacrine (QA) , an anti-malarial drug, against heatstroke in rats." | 7.74 | [Prophylactic effect of quinacrine against experimental heatstroke]. ( Fan, M; Liu, SH; Wang, LM; Wu, Y; Xing, C; Zhao, YQ, 2007) |
| "The present study is to assess the prophylactic effect of quinacrine (QA) , an anti-malarial drug, against heatstroke in rats." | 3.74 | [Prophylactic effect of quinacrine against experimental heatstroke]. ( Fan, M; Liu, SH; Wang, LM; Wu, Y; Xing, C; Zhao, YQ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, YQ | 2 |
| Wang, LM | 2 |
| Xing, C | 2 |
| Liu, SH | 2 |
| Fan, M | 2 |
| Wu, Y | 1 |
1 trial available for quinacrine and Heat Stroke
| Article | Year |
|---|---|
Oral given Mepacrine could increase the resistance to heat environment injury.
Topics: Body Temperature; Heart Rate; Heat Stroke; Heat-Shock Response; Humans; Immunity, Innate; Lactic Aci | 2007 |
1 other study available for quinacrine and Heat Stroke
| Article | Year |
|---|---|
[Prophylactic effect of quinacrine against experimental heatstroke].
Topics: Animals; Cells, Cultured; Corpus Striatum; Fatty Acids; Heat Stroke; Hot Temperature; Male; Membrane | 2007 |