pyruvic acid has been researched along with Heat Stroke in 9 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Heat Stroke: A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 7.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "The present study was performed to assess the prophylactic effect of platonin, a cyanine photosensitizing dye and an inhibitor of proinflammatory cytokines, in an animal model of heatstroke." | 7.73 | Platonin, a cyanine photosensitizing dye, is effective for attenuation of heatstroke in rats. ( Lee, JJ; Liao, JF; Lin, MT; Tsai, CC; Yang, CC, 2006) |
| "In contrast, all vehicle-treated heatstroke animals had lower levels of MAP, cerebral perfusion pressure, cerebral blood flow, and brain partial pressure of oxygen." | 5.35 | L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke. ( Chen, YC; Huang, CI; Lee, CH; Lin, MT; Liu, YC; Wang, LM; Yen, DH, 2008) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 3.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "The present study was performed to assess the prophylactic effect of platonin, a cyanine photosensitizing dye and an inhibitor of proinflammatory cytokines, in an animal model of heatstroke." | 3.73 | Platonin, a cyanine photosensitizing dye, is effective for attenuation of heatstroke in rats. ( Lee, JJ; Liao, JF; Lin, MT; Tsai, CC; Yang, CC, 2006) |
| "Heatstroke was induced by putting the animals in a folded heating pad of 42°C for 68 minutes controlled by circulating hot water." | 1.36 | Inhibition of acute lung inflammation and injury is a target of brain cooling after heatstroke injury. ( Ching-Ping, C; Hsi-Hsing, Y; Juei-Tang, C; Lin, MT, 2010) |
| "In contrast, all vehicle-treated heatstroke animals had lower levels of MAP, cerebral perfusion pressure, cerebral blood flow, and brain partial pressure of oxygen." | 1.35 | L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke. ( Chen, YC; Huang, CI; Lee, CH; Lin, MT; Liu, YC; Wang, LM; Yen, DH, 2008) |
| "Heatstroke was induced by exposing the anesthetized rats to a high ambient temperature (Ta = 43 degrees C) until the moment at which MAP decreased from its peak level." | 1.33 | Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion. ( Ke, DS; Lin, MT; Wang, JL, 2005) |
| "Heatstroke is characterized by hyperthermia, vasoplegic shock, and cerebral ischemia and hypoxia." | 1.33 | Resuscitation from experimental heatstroke by hyperbaric oxygen therapy. ( Gao, CJ; Li, WX; Lin, MT; Niu, KC; Tsai, HM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (88.89) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsi-Hsing, Y | 1 |
| Ching-Ping, C | 1 |
| Juei-Tang, C | 1 |
| Lin, MT | 8 |
| Chou, YT | 1 |
| Lai, ST | 1 |
| Lee, CC | 1 |
| Chang, CK | 1 |
| Chiu, WT | 1 |
| Chang, CP | 2 |
| Wang, JL | 1 |
| Ke, DS | 1 |
| Tsai, HM | 1 |
| Gao, CJ | 1 |
| Li, WX | 1 |
| Niu, KC | 1 |
| Chen, SH | 2 |
| Tsai, CC | 1 |
| Yang, CC | 1 |
| Liao, JF | 1 |
| Lee, JJ | 1 |
| Chen, YC | 1 |
| Liu, YC | 1 |
| Yen, DH | 1 |
| Wang, LM | 1 |
| Huang, CI | 1 |
| Lee, CH | 1 |
| Shen, KH | 1 |
| Lin, CH | 1 |
| Chang, HK | 1 |
| Chen, WC | 1 |
9 other studies available for pyruvic acid and Heat Stroke
| Article | Year |
|---|---|
Inhibition of acute lung inflammation and injury is a target of brain cooling after heatstroke injury.
Topics: Acute Lung Injury; Animals; Body Temperature Regulation; Brain; Bronchoalveolar Lavage Fluid; Cytoki | 2010 |
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus | 2003 |
Effect of hypervolaemic haemodilution on cerebral glutamate, glycerol, lactate and free radicals in heatstroke rats.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Free Radicals; Glutamic Acid; Glycerol; | 2004 |
Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Catechols; Cerebrovascular Circulation; Glut | 2005 |
Resuscitation from experimental heatstroke by hyperbaric oxygen therapy.
Topics: Animals; Biomarkers; Brain Diseases; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; H | 2005 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; | 2005 |
Platonin, a cyanine photosensitizing dye, is effective for attenuation of heatstroke in rats.
Topics: Animals; Cerebrovascular Circulation; Cytokines; Glutamic Acid; Glycerol; Heat Stroke; Hot Temperatu | 2006 |
L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke.
Topics: Animals; Arginine; Cerebrovascular Circulation; Cerebrovascular Disorders; Cytokines; Encephalitis; | 2008 |
Premarin can act via estrogen receptors to rescue mice from heatstroke-induced lethality.
Topics: Animals; Apoptosis; Brain; Cytokines; Dose-Response Relationship, Drug; Estradiol; Estrogens, Conjug | 2008 |