An pathway inhibitor that inhibits the synthesis of cellulose.
ChEBI ID: 63958
| Member | Definition | Class |
|---|---|---|
| ancymidol | A tertiary alcohol that is methanol in which the hydrogens attached to the carbon are replaced by cyclopropyl, p-methoxyphenyl and pyrimidin-5-yl groups. By inhibiting gibberellin biosynthesis, ancymidol reduces plant growth, resulting in reduced internode elongation and thus more compact plants. It is used in the commercial production of a wide variety of container-grown bedding and foliage plants, including chrysanthemums, Easter lilies and poinsettias. | ancymidol |
| dichlobanil | A nitrile that is benzonitrile which is substituted by chlorines at positions 2 and 6. A cellulose synthesis inhibitor, it is used as a pre-emergent and early post-emergent herbicide. | 2,6-dichlorobenzonitrile |
| isoxaben | A benzamide obtained by formal condensation of the carboxy group of 2,6-dimethoxybenzoic acid and the amino group of 3-(3-methylpentan-3-yl)-1,2-oxazol-5-amine. | isoxaben |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 9 (4.95) | 18.7374 |
| 1990's | 34 (18.68) | 18.2507 |
| 2000's | 65 (35.71) | 29.6817 |
| 2010's | 67 (36.81) | 24.3611 |
| 2020's | 7 (3.85) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 5 (2.62%) | 6.00% |
| Case Studies | 1 (0.52%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 185 (96.86%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 55.7743 | 2 | 4 |
| AR protein | Homo sapiens (human) | Potency | 61.7010 | 6 | 10 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 33.1885 | 2 | 4 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 68.7989 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 51.1198 | 5 | 7 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 52.4391 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 43.4924 | 5 | 8 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 54.4885 | 1 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 28.5628 | 2 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 51.0023 | 1 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 48.1514 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 71.5189 | 3 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 33.9591 | 3 | 5 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 37.1374 | 2 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 55.1293 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 1.8911 | 2 | 3 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 54.6489 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 43.7432 | 2 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 28.2943 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 17.5218 | 2 | 3 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 54.3536 | 2 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 56.7886 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 24.5412 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 48.1514 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Aromatase | Rattus norvegicus (Norway rat) | EC50 | 2.0000 | 1 | 1 |