Any compound that inhibits the biosynthesis of any phospholipid.
| Member | Definition | Class |
|---|
| edifenphos | An organic thiophosphate that is the O-ethyl-S,S-diphenyl ester of phosphorodithioic acid. Used to control a variety of fungal diseases on rice including blast, ear blight and stem rot. Edifenphos is moderately toxic to mammals and fish but poses more of a risk to aquatic invertebrates. | edifenphos |
| isoprothiolane | A malonate ester that is diisopropyl malonate in which the two methylene hydrogens at position 2 are replaced by a 1,3-dithiolan-2-ylidene group. An insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. | isoprothiolane |
| o,o-diisopropyl-s-benzylthiophosphate | An organic thiophosphate that is the S-benzyl O,O-diisopropyl ester of phosphorothioic acid. Used as a rice fungicide to control leaf and ear blast, stem rot and sheath blight. | iprobenfos |
| pyrazophos | A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A profungicide (by hydrolysis of the thionophosphate group to afford the corresponding 2-hydroxypyrazolopyrimidine fungicide), it is used to control Erysiphe, Helminthosporium and Rhynchospium in cereals. | pyrazophos |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 33.6504 | 4 | 8 |
| AR protein | Homo sapiens (human) | Potency | 56.6585 | 6 | 9 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 0.0757 | 2 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 39.8107 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 31.6228 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 39.8107 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 33.8779 | 4 | 5 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 52.4828 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 47.2795 | 6 | 9 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 48.9662 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.3369 | 2 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 23.1900 | 1 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 14.2264 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 17.3739 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 22.3872 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.9551 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 30.8956 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 12.3369 | 3 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 54.9410 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 32.5070 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 9.6885 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 42.4689 | 3 | 5 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 23.8580 | 2 | 4 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 24.1348 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 24.1348 | 2 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 23.2626 | 2 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 0.1000 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 36.6216 | 5 | 5 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 43.0090 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 54.9410 | 1 | 1 |