Page last updated: 2024-12-08
spirodiclofen
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
spirodiclofen: an acaricide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 177863 |
| CHEMBL ID | 2227839 |
| CHEBI ID | 38639 |
| SCHEMBL ID | 27234 |
| MeSH ID | M0495300 |
Synonyms (44)
| Synonym |
|---|
| CHEBI:38639 , |
| spirodiclofen |
| 148477-71-8 |
| 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate |
| 2,2-dimethylbutanoic acid [2-(3,5-dichlorophenyl)-3-oxo-4-oxaspiro[4.5]dec-1-en-1-yl] ester |
| A808770 |
| NCGC00182605-01 |
| baj 2740 |
| spirodiclofen [iso] |
| 3x7g31f5mx , |
| envidor |
| unii-3x7g31f5mx |
| butanoic acid, 2,2-dimethyl-, 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro(4.5)dec-3-en-4-yl ester |
| C18553 |
| dtxsid6034928 , |
| cas-148477-71-8 |
| tox21_301133 |
| NCGC00255032-01 |
| dtxcid201334167 |
| 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl) 2,2-dimethylbutyrate |
| FT-0631177 |
| hsdb 7940 |
| AKOS015895782 |
| spirodiclofen [mi] |
| 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro(4.5)dec-3-en-4-yl 2,2-dimethylbutanoate |
| baj2740 |
| 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro(4.5)dec-3-en-4-yl 2,2-dimethylbutyrate |
| baj-2740 |
| SCHEMBL27234 |
| CHEMBL2227839 |
| CS-5165 |
| HY-B0826 |
| DTDSAWVUFPGDMX-UHFFFAOYSA-N |
| [3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl] 2,2-dimethylbutanoate |
| spirodiclofen, pestanal(r), analytical standard |
| spirodiclofen 10 microg/ml in cyclohexane |
| J-008475 |
| pesticide7_spirodiclofen_c21h24cl2o4_butanoic acid, 2,2-dimethyl-, 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl ester |
| BCP21407 |
| Q425807 |
| spirodiclofen 1000 microg/ml in acetone |
| MS-27098 |
| spirodiclofen 100 microg/ml in acetonitrile |
| YFA47771 |
Research Excerpts
Overview
Spirodiclofen is a selective, non-systemic acaricide from the new chemical class of tetronic acid derivatives. It targets lipid biosynthesis by inhibiting acetyl-coenzyme A carboxylase.
Effects
| Excerpt | Reference | Relevance |
|---|---|---|
| "Spirodiclofen (Envidor(®)) has been a commonly used acaricide for several years." | ( Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. Kramer, T; Nauen, R, 2011) | 1.45 |
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| " Low efficacy and development of Varroa mite resistance to currently used Varroacides has increased the demand for innovative, effective treatment tool options that exhibit high efficacy, while minimizing adverse effects on honey bee fitness." | ( Evaluation of potential miticide toxicity to Varroa destructor and honey bees, Apis mellifera, under laboratory conditions. Bahreini, R; de Herdt, O; Docherty, C; Feindel, D; Muirhead, S; Nasr, M, 2020) | 0.56 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " The compounds were tested at their respective maximum field recommended concentration (MFRC), and, when strong lethal effects were observed, a dose-response assay with a dilution series of the MFRC was undertaken to calculate LC(50) values." | ( Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. Besard, L; Cuvelier, X; Mommaerts, V; Smagghe, G; Sterk, G; Vandeven, J, 2010) | 0.36 |
| " For oral exposures via treated sugar water, the dose-response assay showed the LC(50) values for abamectin, bifenazate, bifenthrin and etoxazole to be 1/15 MFRC (1." | ( Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. Besard, L; Cuvelier, X; Mommaerts, V; Smagghe, G; Sterk, G; Vandeven, J, 2010) | 0.36 |
| "5 mg•kg⁻¹) of spirodiclofen of EU for wolfberry, after recommended dosage being sprayed for once, fresh wolfberry fruit was safe to eat after 5 days, and dry wolfberry fruit was safe to eat after 21 days." | ( [Dissipation dynamics of spirodiclofen in wolfberry fruit]. Chen, J; Guo, K; Jin, HY; Li, JL; Lin, C; Liu, S; Ma, SC; Qiao, HL; Wei, H; Xu, CQ; Xu, R, 2016) | 1.1 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (4)
| Class | Description |
|---|---|
| organochlorine acaricide | Any organochlorine pesticide that has been used as an acaricide. |
| dichlorobenzene | Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions. |
| oxaspiro compound | A spiro compound in which at least one of the cyclic components is an oxygen heterocyle. |
| gamma-lactone | A lactone having a five-membered lactone ring. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Protein Targets (22)
Potency Measurements
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 31.7055 | 0.0072 | 15.7588 | 89.3584 | AID1224835 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 54.9410 | 3.1890 | 29.8841 | 59.4836 | AID1224846; AID1224894 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 54.4827 | 0.0007 | 14.5928 | 83.7951 | AID1259369 |
| AR protein | Homo sapiens (human) | Potency | 4.3266 | 0.0002 | 21.2231 | 8,912.5098 | AID743035; AID743063 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 4.8558 | 0.0006 | 57.9133 | 22,387.1992 | AID1259378 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 30.6379 | 0.0030 | 41.6115 | 22,387.1992 | AID1159553 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 37.7341 | 0.0015 | 30.6073 | 15,848.9004 | AID1224841; AID1224842; AID1224849; AID1259401 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 48.5577 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 43.9893 | 0.0002 | 29.3054 | 16,493.5996 | AID1259244; AID743069; AID743075; AID743078; AID743079; AID743080; AID743091 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 1.8815 | 0.0010 | 19.4141 | 70.9645 | AID743094; AID743140 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 10.8707 | 0.0017 | 23.8393 | 78.1014 | AID743083 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 13.8006 | 0.1434 | 27.6121 | 59.8106 | AID1159516 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 61.6448 | 19.7391 | 45.9784 | 64.9432 | AID1159509 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 1.9494 | 0.0578 | 21.1097 | 61.2679 | AID1159526; AID1159528 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 49.7264 | 0.0003 | 23.4451 | 159.6830 | AID743065; AID743067 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 61.6448 | 0.0420 | 27.3789 | 61.6448 | AID743210 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 66.7865 | 0.0006 | 27.2152 | 1,122.0200 | AID743202; AID743219 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 61.1306 | 0.0015 | 57.7890 | 15,848.9004 | AID1259244 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 11.2365 | 0.0023 | 19.5956 | 74.0614 | AID651631; AID720552 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 61.1306 | 0.0015 | 51.7393 | 15,848.9004 | AID1259244 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 27.3060 | 0.0119 | 17.9420 | 71.5630 | AID651632 |
| Ataxin-2 | Homo sapiens (human) | Potency | 27.3060 | 0.0119 | 12.2221 | 68.7989 | AID651632 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
Biological Processes (141)
Molecular Functions (40)
Ceullar Components (27)
Bioassays (53)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1103883 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as average number of eggs laid (fecundity) at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 48 hr (Rvb | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1110870 | Insecticidal activity against spirodiclofen-susceptible Tetranychus urticae LS-VL (two-spotted spider mite) larvae in kidney bean leaf disks assessed as mortality after 1 day | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1111812 | Insecticidal activity against Panonychus ulmi HS in plum tree leaf assessed as larvae mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1104465 | Contact toxicity against worker Bombus terrestris (bumblebee) assessed as mortality at 96 mg a.i./l applied on the dorsal thorax for 11 weeks measured everyday for 3 days followed by once a week for 11 weeks | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. |
| AID1110840 | Insecticidal activity against haploid F2 progeny generated from reciprocal cross between male Tetranychus urticae LS-VL (two-spotted spider mite) with female Tetranychus urticae SR-VP in kidney bean leaf disk assessed as mortality | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1103903 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as corrected mortality at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1111801 | Resistance ratio, LC50 for larvae Panonychus ulmi Ge15/09 to LC50 for larvae Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111808 | Insecticidal activity against Panonychus ulmi Ge16/09 in plum tree leaf assessed as larvae mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1110862 | Resistance ratio of LC50 for spirodiclofen-resistant Tetranychus urticae SR-VP (two-spotted spider mite) larvae reared under continuous pressure of 5000 mg/L spirodiclofen for 5 months to LC50 for spirodiclofen-susceptible Tetranychus urticae LS-VL (two-s | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1082837 | Insecticidal activity against Aphis fabae (black bean aphid) apterous third-instar nymphae in tender soybean shoots assessed as inhibition activity at 10 mg/L after 72 hr | 2012 | Journal of agricultural and food chemistry, May-16, Volume: 60, Issue:19 | Design, synthesis, and analysis of the quantitative structure-activity relationships of 4-phenyl-acyl-substituted 3-(2,5-dimethylphenyl)-4-hydroxy-1-azaspiro[4.5]dec-3-ene-2,8-dione derivatives. |
| AID1111795 | Resistance ratio, LC50 for egg Panonychus ulmi Ge16/09 to LC50 for egg Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1103857 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as repellency at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr (Rvb = 16.1%) | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1110843 | Insecticidal activity against diploid F1 progeny generated from reciprocal cross between female Tetranychus urticae LS-VL (two-spotted spider mite) with male Tetranychus urticae SR-VP in kidney bean leaf disk assessed as mortality | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1110842 | Insecticidal activity against diploid F1 progeny generated from reciprocal cross between male Tetranychus urticae LS-VL (two-spotted spider mite) with female Tetranychus urticae SR-VP in kidney bean leaf disk assessed as mortality | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1110864 | Insecticidal activity against spirodiclofen-resistant Tetranychus urticae SR-VP (two-spotted spider mite) larvae maintained on bean plants sprayed with 5000 mg/L spirodiclofen assessed as mortality | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1111789 | Resistance ratio, LC50 for larvae Panonychus ulmi HS to LC50 for larvae Panonychus ulmi PSR TK | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111810 | Insecticidal activity against Panonychus ulmi Ge14/09 in plum tree leaf assessed as larvae mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1110867 | Insecticidal activity against spirodiclofen-resistant Tetranychus urticae SR-VP (two-spotted spider mite) larvae reared under continuous pressure of 5000 mg/L spirodiclofen for 5 months in kidney bean leaf disks assessed as mortality measured after 1 day | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1111804 | Insecticidal activity against Panonychus ulmi Ge15/09 in plum tree leaf assessed as egg mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1104394 | Contact toxicity against worker Bombus terrestris (bumblebee) assessed as reduction in reproduction at 96 mg a.i./l applied on the dorsal thorax for 11 weeks measured once a week for 11 weeks relative to control | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. |
| AID1111797 | Resistance ratio, LC50 for egg Panonychus ulmi Ge14/09 to LC50 for egg Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1104457 | Toxicity against worker Bombus terrestris (bumblebee) assessed as mortality at 96 mg a.i./l, po administered through sugar water for 11 weeks measured everyday for 3 days followed by once a week for 11 weeks | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. |
| AID1082839 | Larvicidal activity against Tetranychus cinnabarinus ( carmine spider mite ) fifty third-instar mite larvae assessed as inhibition activity at 10 mg/L after 72 hr | 2012 | Journal of agricultural and food chemistry, May-16, Volume: 60, Issue:19 | Design, synthesis, and analysis of the quantitative structure-activity relationships of 4-phenyl-acyl-substituted 3-(2,5-dimethylphenyl)-4-hydroxy-1-azaspiro[4.5]dec-3-ene-2,8-dione derivatives. |
| AID1103913 | Ovicidal activity against Metaseiulus occidentalis eggs in bean leaf disk infested with two-spotted spider mites assessed as corrected cumulative mortality at 240 g/L SC formulation treated using worst-case laboratory exposure procedure measured after 144 | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1112048 | Insecticidal activity against third-instar nymph of Aphis fabae (black bean aphids) assessed as mortality at 4 mg/L after 72 hr by spray method | 2012 | Pest management science, Jan, Volume: 68, Issue:1 | Synthesis and bioactivity evaluation of novel spiromesifen derivatives. |
| AID1111798 | Resistance ratio, LC50 for egg Panonychus ulmi Ge13/09 to LC50 for egg Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1082838 | Larvicidal activity against Tetranychus cinnabarinus (carmine spider mite) fifty third-instar mite larvae assessed as inhibition activity at 100 mg/L after 72 hr | 2012 | Journal of agricultural and food chemistry, May-16, Volume: 60, Issue:19 | Design, synthesis, and analysis of the quantitative structure-activity relationships of 4-phenyl-acyl-substituted 3-(2,5-dimethylphenyl)-4-hydroxy-1-azaspiro[4.5]dec-3-ene-2,8-dione derivatives. |
| AID1111807 | Insecticidal activity against Panonychus ulmi HS in plum tree leaf assessed as egg mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1082836 | Insecticidal activity against Aphis fabae (black bean aphid) apterous third-instar nymphae in tender soybean shoots assessed as inhibition activity at 100 mg/L after 72 hr | 2012 | Journal of agricultural and food chemistry, May-16, Volume: 60, Issue:19 | Design, synthesis, and analysis of the quantitative structure-activity relationships of 4-phenyl-acyl-substituted 3-(2,5-dimethylphenyl)-4-hydroxy-1-azaspiro[4.5]dec-3-ene-2,8-dione derivatives. |
| AID1111792 | Insecticidal activity against Panonychus ulmi PSR-TK in plum tree leaf assessed as mortality at egg stage compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111809 | Insecticidal activity against Panonychus ulmi Ge15/09 in plum tree leaf assessed as larvae mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111803 | Insecticidal activity against Panonychus ulmi Ge16/09 in plum tree leaf assessed as egg mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1104388 | Toxicity against worker Bombus terrestris (bumblebee) assessed as reduction in reproduction at 96 mg a.i./l, po administered through sugar water for 11 weeks measured once a week for 11 weeks relative to control | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. |
| AID1110860 | Resistance ratio of LC50 for spirodiclofen-resistant Tetranychus urticae SR-VP (two-spotted spider mite) eggs to LC50 for spirodiclofen-susceptible Tetranychus urticae LS-VL (two-spotted spider mite) eggs | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1111799 | Resistance ratio, LC50 for larvae Panonychus ulmi Ge16/09 to LC50 for larvae Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1104363 | Toxicity against worker Bombus terrestris (bumblebee) assessed as reduction in reproduction at 96 mg a.i./l, po administered through pollen for 11 weeks measured once a week for 11 weeks | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. |
| AID1111802 | Resistance ratio, LC50 for larvae Panonychus ulmi Ge13/09 to LC50 for larvae Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1110863 | Insecticidal activity against spirodiclofen-resistant Tetranychus urticae SR-VP (two-spotted spider mite) larvae maintained on bean plants sprayed with 5000 mg/L spirodiclofen assessed as mortality measured at 6 months after mite transfer onto unsprayed b | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1111793 | Insecticidal activity against Panonychus ulmi PSR-TK in plum tree leaf assessed as mortality at larvae stage compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1103889 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as average number of eggs laid (fecundity) at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 24 hr (Rvb | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1103877 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as average number of eggs laid (fecundity) at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr (Rvb | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1111790 | Resistance ratio, LC50 for egg Panonychus ulmi HS to LC50 for egg Panonychus ulmi PSR TK | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1103869 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as repellency at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 24 hr (Rvb = 3.6%) | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1111811 | Insecticidal activity against Panonychus ulmi Ge13/09 in plum tree leaf assessed as larvae mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111796 | Resistance ratio, LC50 for egg Panonychus ulmi Ge15/09 to LC50 for egg Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111800 | Resistance ratio, LC50 for larvae Panonychus ulmi Ge14/09 to LC50 for larvae Panonychus ulmi HS | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1110866 | Insecticidal activity against spirodiclofen-resistant Tetranychus urticae SR-VP (two-spotted spider mite) eggs in kidney bean leaf disks assessed as mortality measured after 1 day | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1110869 | Insecticidal activity against spirodiclofen-susceptible Tetranychus urticae LS-VL (two-spotted spider mite) eggs in kidney bean leaf disks assessed as mortality after 1 day | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1104417 | Toxicity against worker Bombus terrestris (bumblebee) assessed as mortality at 96 mg a.i./l, po administered through pollen for 11 weeks measured everyday for 3 days followed by once a week for 11 weeks | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects. |
| AID1110841 | Insecticidal activity against haploid F2 progeny generated from reciprocal cross between female Tetranychus urticae LS-VL (two-spotted spider mite) with male Tetranychus urticae SR-VP in kidney bean leaf disk assessed as mortality | 2009 | Pest management science, Apr, Volume: 65, Issue:4 | Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). |
| AID1103863 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as repellency at 0.3024 g AI/L treated using worst-case laboratory exposure procedure measured after 48 hr (Rvb = 13.6%) | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1111805 | Insecticidal activity against Panonychus ulmi Ge14/09 in plum tree leaf assessed as egg mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| AID1111806 | Insecticidal activity against Panonychus ulmi Ge13/09 in plum tree leaf assessed as egg mortality compound treated by spray application measured after 7 to 8 days treatment | 2011 | Pest management science, Oct, Volume: 67, Issue:10 | Monitoring of spirodiclofen susceptibility in field populations of European red mites, Panonychus ulmi (Koch) (Acari: Tetranychidae), and the cross-resistance pattern of a laboratory-selected strain. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (38)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 20 (52.63) | 24.3611 |
| 2020's | 12 (31.58) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 40.50
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (40.50) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 38 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||