Page last updated: 2024-11-13

cycloxaprid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

cycloxaprid: a neonicotinoid insecticide; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID58496250
SCHEMBL ID888470
MeSH IDM0587655

Synonyms (6)

Synonym
SCHEMBL888470
1-((6-chloropyridin-3-yl)methyl)-9-nitro-2,3,5,6,7,8-hexahydro -1h-5,8-epoxyimidazo[1,2-a]azepine
NDHXMRFNYMNBKO-UHFFFAOYSA-N
1-((6-chloropyridin-3-yl)methyl)-9-nitro-2,3,5,6,7,8-hexahydro-1h-5,8-epoxyimidazo[1,2-a]azepine
cycloxaprid
1203791-41-6

Research Excerpts

Overview

Cycloxaprid (CYC) is a promising neonicotinoid due to its insecticidal effectiveness and low cross resistance, but little is known about its fate in soils. It is currently under development in China for agricultural pest control.

ExcerptReferenceRelevance
"Cycloxaprid is a potentially promising substitute, but its metabolism in plants is still poorly understood."( Translocation and metabolism of the chiral neonicotinoid cycloxaprid in oilseed rape (Brassica napus L.).
Cheng, X; Shao, S; Ye, Q; Yu, Z; Zhang, S; Zheng, R, 2022
)
1.69
"Cycloxaprid (CYC) is a promising neonicotinoid due to its insecticidal effectiveness and low cross resistance, but little is known about its fate in soils."( Fate of the neonicotinoid insecticide cycloxaprid in different soils under oxic conditions.
Cheng, X; Wang, Y; Ye, Q; Zhang, H; Zhang, S, 2022
)
1.71
"Cycloxaprid is a slow-acting and nonrepellent insecticide against S. "( Toxicity, horizontal transfer, and physiological and behavioral effects of cycloxaprid against Solenopsis invicta (Hymenoptera: Formicidae).
Cai, J; Chen, J; Chen, X; He, Y; Lu, Y; Wang, C; Wang, L; Wen, X; Xu, Z; Zhang, J; Zhang, L, 2022
)
2.39
"Cycloxaprid is a novel cis-nitromethylene configuration neonicotinoid insecticide that is different from trans-configuration neonicotinoids like imidacloprid and thiamethoxam."( Cross-Resistance and Fitness Costs of the cis-Nitromethylene Neonicotinoid Cycloxaprid Resistance in Melon Aphid, Aphis gossypii (Hemiptera: Aphididae).
Chen, Z; Dong, W; Gao, X; Li, H; Liang, P; Shang, J; Shi, X; Wang, C; Yang, H; Zhang, H, 2022
)
1.67
"Cycloxaprid is a novel cis-configuration neonicotinoid insecticide that is effective against a wide range of imidacloprid-resistant pests."( Cycloxaprid: a novel cis-nitromethylene neonicotinoid insecticide to control Bemisia tabaci.
Cui, L; Rui, C; Wang, L; Wang, Q; Yuan, H, 2020
)
2.72
"Cycloxaprid (CYC) is a new cis-configuration neonicotinoid insecticide, which is currently under development in China for agricultural pest control. "( Photostability study of cis-configuration neonicotinoid insecticide cycloxaprid in water.
Deng, Y; Hou, S; Xu, X; Zhuang, Y, 2017
)
2.13
"Cycloxaprid is a new oxabridged cis-configuration neonicotinoid insecticide, the resistance development potential and underlying resistance mechanism of which were investigated in the small brown planthopper, Laodelphax striatellus (Fallén), an important agricultural pest of rice."( Resistance to cycloxaprid in Laodelphax striatellus is associated with altered expression of nicotinic acetylcholine receptor subunits.
Fang, J; Guo, H; Han, Y; He, P; Li, Z; Liu, Z; Wang, L; Yang, Q; Zhang, Y, 2018
)
2.28
"Cycloxaprid is a novel cis-configuration neonicotinoid insecticide that is effective against a wide range of insect pests, including those that are resistant to conventional neonicotinoids. "( Sublethal effects of the novel cis-nitromethylene neonicotinoid cycloxaprid on the cotton aphid Aphis gossypii Glover (Hemiptera: Aphididae).
Cui, L; Rui, C; Wang, Q; Yuan, H, 2018
)
2.16
"Cycloxaprid (CYC) is a novel neonicotinoid prepared from the (nitromethylene)imidazole (NMI) analogue of imidacloprid. "( Cycloxaprid insecticide: nicotinic acetylcholine receptor binding site and metabolism.
Casida, JE; Shao, X; Swenson, TL, 2013
)
3.28
"Cycloxaprid (CYC) is a novel broad-spectrum neonicotinoid insecticide that has been developed for agricultural pest control. "( Assessment of the environmental fate of cycloxaprid in flooded and anaerobic soils by radioisotopic tracing.
Fu, Q; Li, C; Li, Z; Liu, X; Shao, X; Xu, X; Ye, Q; Zhang, H, 2016
)
2.14

Bioavailability

ExcerptReferenceRelevance
"82, which suggested CYC immobilization in the soil resulted in its bioavailability being reduced which enhanced its degradation."( Bioavailability and release of nonextractable (bound) residues of chiral cycloxaprid using geophagous earthworm Metaphire guillelmi in rice paddy soil.
Li, C; Li, Z; Liu, X; Shao, X; Xu, X; Ye, Q; Zhang, H, 2015
)
0.65
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (32)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's20 (62.50)24.3611
2020's12 (37.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.76

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.76 (24.57)
Research Supply Index3.50 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.76)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.13%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other31 (96.88%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]