paichongding

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

paichongding: a neonicotinoid insecticide; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	44571837
CHEMBL ID	519270
SCHEMBL ID	255346
MeSH ID	M0593816

Synonyms (9)

Synonym
paichongding
CHEMBL519270
SCHEMBL255346
DTXSID9058498
948994-16-9
1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-3,5,6,7-tetrahydro-2h-imidazo[1,2-a]pyridine
1-((6-chloropyridin-3-yl)methyl)-7-methyl-8-nitro-5-propoxy-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridine
1-[(6-chloro-3-pyridinyl)methyl]-1,2,3,5,6,7-hexahydro-7-methyl-8-nitro-5-propoxyimidazo[1,2-a]pyridine; 1-[(6-chloropyridin-3-yl)-methyl]-5-propoxy-7-methyl-8-nitro-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridine; 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-
1ST20545

Research Excerpts

Overview

Paichongding is an adicyclicnitromethylene neonicotinoid insecticide with a cis-configuration. It is currently marketed as racemate against sucking and biting insects.

Excerpt	Reference	Relevance
"Paichongding is a novel neonicotinoid insecticide developed in 2008."	( Physiological efects of paichongding applied to rice on the Nilaparvata lugens (Stå l), the brown planthopper. Qin, X; Shi, Y; Zhang, J; Zhang, R, 2014)	1.43
"Paichongding is an adicyclicnitromethylene neonicotinoid insecticide with a cis-configuration. "	( Analysis of the Time-Concentration-Mortality Response of Nilaparvata lugens (Hemiptera: Delphacidae) to Paichongding. Chen, Y; Liu, J; Liu, Y; Qin, X; Shi, YW; Wang, M; Wang, Z; Zhang, R, 2015)	2.07
"Paichongding (IPP) is a novel neonicotinoid insecticide and was developed recently in China."	( Impact of the novel neonicotinoid insecticide Paichongding on bacterial communities in yellow loam and Huangshi soils. Cai, J; Cai, Z; Ma, J; Wang, J; Yang, G; Zhao, X, 2016)	1.41
"Paichongding (IPP) is a novel cis-nitromethylene neonicotinoid insecticide, which was recently developed in China."	( Effects of the novel cis-nitromethylene neonicotinoid insecticide Paichongding on enzyme activities and microorganisms in yellow loam and Huangshi soils. Cai, Z; Chen, J; Ma, J; Rong, Y; Wang, J; Zhang, W; Zhao, X, 2016)	1.39
"Paichongding is a chiral neonicotinoid insecticide currently marketed as racemate against sucking and biting insects. "	( Stereoselective Degradation and Transformation Products of a Novel Chiral Insecticide, Paichongding, in Flooded Paddy Soil. Li, C; Li, J; Li, Z; Wang, H; Wang, W; Wu, C; Ye, Q; Zhang, S, 2016)	2.1

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay ID	Title	Year	Journal	Article
AID1082710	Insecticidal activity against adult Aphis craccivora (cowpea aphid) assessed as larvicidal activity at 500 mg/l after 24 hr	2012	Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1	Design, synthesis, and particular biological behaviors of chain-opening nitromethylene neonicotinoids with cis configuration.
AID1082709	Insecticidal activity against adult Aphis craccivora (cowpea aphid) assessed as larvicidal activity after 24 hr	2012	Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1	Design, synthesis, and particular biological behaviors of chain-opening nitromethylene neonicotinoids with cis configuration.
AID371212	Insecticidal activity against Aphis craccivora assessed as mortality at 500 mg/L	2008	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24	cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine.
AID371213	Insecticidal activity against Aphis craccivora	2008	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24	cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine.
AID371215	Insecticidal activity against imidacloprid-resistant Nilaparvata lugens	2008	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24	cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine.
AID371214	Insecticidal activity against imidacloprid-sensitive Nilaparvata lugens	2008	Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24	cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (5.88)	29.6817
2010's	15 (88.24)	24.3611
2020's	1 (5.88)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.14

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	13.14 (24.57)
Research Supply Index	2.89 (2.92)
Research Growth Index	6.03 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (13.14)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	17 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
nitenpyram nitenpyram: a nitromethylene neonicotinoid insecticide; structure in first source. (E)-nitenpyram : A nitenpyram in which the double bond has E configuration.. nitenpyram : A C-nitro compound consisting of 2-nitroethene-1,1-diamine where one of the nitrogens bears ethyl and (6-chloro-3-pyridinyl)methyl while the other nitrogen carries a methyl group.	2.07	1	chloropyridyl insecticide; nitenpyram
clay Clay: A naturally-occurring rock or soil constituent characterized by particles with a diameter of less than 0.005 mm. It is composed primarily of hydrous aluminum silicates, trace amounts of metal OXIDES, and organic matter.	2.13	1
cycloxaprid cycloxaprid: a neonicotinoid insecticide; structure in first source	7.6	1
imidacloprid (E)-imidacloprid : The E-isomer of imidacloprid.	2.46	2	imidacloprid; imidazolidines; monochloropyridine	environmental contaminant; genotoxin; neonicotinoid insectide; nicotinic acetylcholine receptor agonist; xenobiotic
imidacloprid imidacloprid: systemic & contact insecticide exhibiting low mammalian toxicity; structure given in first source; it is one of the neonicotinoid insecticides, which acts as an antagonist by binding to postsynaptic nicotinic receptors in the insect central nervous system. imidacloprid : An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1.	2.6	1	imidacloprid; imidazolidines; monochloropyridine	environmental contaminant; genotoxin; neonicotinoid insectide; nicotinic acetylcholine receptor agonist; xenobiotic

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