A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex.
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
acetylcholinesterase | Homo sapiens (human) | Potency | 89.3584 | 1 | 1 |
activating transcription factor 6 | Homo sapiens (human) | Potency | 1.0962 | 1 | 1 |
AR protein | Homo sapiens (human) | Potency | 12.1555 | 8 | 15 |
aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 7.6959 | 1 | 1 |
Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 23.1530 | 2 | 2 |
cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 1.2622 | 1 | 1 |
cytochrome P450 2D6 | Homo sapiens (human) | Potency | 31.7055 | 1 | 1 |
cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 20.0048 | 1 | 1 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 26.0027 | 1 | 2 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 20.0658 | 11 | 20 |
estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 52.8526 | 2 | 3 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 9.1429 | 9 | 15 |
farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 36.4947 | 3 | 4 |
Fumarate hydratase | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
G | Vesicular stomatitis virus | Potency | 1.2622 | 1 | 1 |
GLI family zinc finger 3 | Homo sapiens (human) | Potency | 1.6012 | 2 | 4 |
glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 21.4640 | 3 | 5 |
Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 8.6879 | 1 | 2 |
Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 15.9623 | 1 | 1 |
HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 1.2622 | 1 | 1 |
hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 58.6042 | 1 | 1 |
Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 1.2622 | 1 | 2 |
Interferon beta | Homo sapiens (human) | Potency | 14.1454 | 2 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 5.5980 | 3 | 6 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 9.2881 | 1 | 1 |
nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 13.5791 | 2 | 3 |
peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 26.4137 | 5 | 9 |
Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 52.2096 | 3 | 4 |
polyprotein | Zika virus | Potency | 14.1254 | 1 | 1 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 18.7152 | 2 | 4 |
pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 4.9693 | 1 | 2 |
progesterone receptor | Homo sapiens (human) | Potency | 49.6998 | 2 | 3 |
RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 5.2255 | 2 | 4 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 10.9036 | 3 | 5 |
retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 39.8427 | 3 | 3 |
SMAD family member 2 | Homo sapiens (human) | Potency | 42.5932 | 2 | 2 |
SMAD family member 3 | Homo sapiens (human) | Potency | 42.5932 | 2 | 2 |
TDP1 protein | Homo sapiens (human) | Potency | 0.2302 | 2 | 2 |
thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 3.7799 | 2 | 4 |
thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.0126 | 1 | 1 |
thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 52.7001 | 4 | 5 |
v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 65.7549 | 1 | 1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 27.4244 | 2 | 2 |
Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 8.6879 | 1 | 2 |