Page last updated: 2024-12-08
dihydrocorynantheol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
dihydrocorynantheol: alkaloid from Mitragyna species; isomer of corynantheidol; [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 164952 |
| CHEMBL ID | 4076672 |
| SCHEMBL ID | 3132906 |
| MeSH ID | M0050579 |
Synonyms (7)
| Synonym |
|---|
| corynan-17-ol |
| dihydrocorynantheol |
| 2270-72-6 |
| 2-[(2r,3r,12bs)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]ethanol |
| SCHEMBL3132906 |
| DTXSID20945368 |
| CHEMBL4076672 |
Research Excerpts
Overview
Dihydrocorynantheol is an alkaloid compound isolated from Esenbeckia leiocarpa.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Dihydrocorynantheol (DHC) is an alkaloid compound isolated from Esenbeckia leiocarpa Engl. " | ( Relationship of chemical structure and anti-inflammatory activity of dihydrocorynantheol and its analogues. Dos Reis, GO; Espindola, L; Fröde, TS; Heller, M; Horst, H; Micke, GA; Pereira, DF; Pizzolatti, MG; Pozzatti, P, 2013) | 2.07 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1460873 | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 0.0624 to 40 uM incubated for 48 hrs by MTT assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Indole Alkaloids from Hunteria zeylanica. |
| AID1460875 | Insecticidal activity against Rhodobium porosum adults placed on 5 secs compound pre-treated bean leaves after 1 day by leaf dipping protocol based method | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Indole Alkaloids from Hunteria zeylanica. |
| AID1460872 | Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability at 0.0624 to 40 uM incubated for 48 hrs by MTT assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Indole Alkaloids from Hunteria zeylanica. |
| AID1460874 | Cytotoxicity against human A549 cells assessed as reduction in cell viability at 0.0624 to 40 uM incubated for 48 hrs by MTT assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Indole Alkaloids from Hunteria zeylanica. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.00
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.00) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||