Page last updated: 2024-12-06

carbamothioic acid, s,s'-(2-(dimethylamino)-1,3-propanediyl) ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

carbamothioic acid, S,S'-(2-(dimethylamino)-1,3-propanediyl) ester: RN given refers to parent cpd; Padan refers to mono-HCl [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID27159
CHEMBL ID1436987
CHEBI ID3436
SCHEMBL ID25918
MeSH IDM0101975

Synonyms (45)

Synonym
sanvex
thiobel
brn 1954913
t-1258
s,s'-(2-(dimethylamino)-1,3-propanediyl)dicarbamothioate
cartap [bsi:iso]
padan
carbamic acid, thio-, s,s'-(2-(dimethylamino)trimethylene) ester
cartap
15263-53-3
NCGC00166201-01
s,s'-(2-(dimethylamino)-1,3-propanediyl) dicarbamothioate
carbamothioic acid, s,s'-(2-(dimethylamino)-1,3-propanediyl) ester
s,s'-(2-dimethylaminotrimethylene) bis(thiocarbamate)
2-dimethylamino-1,3-bis(carbamoylthio)propane
s,s'-[2-(dimethylamino)propane-1,3-diyl] bis(thiocarbamate)
CHEBI:3436 ,
1,3-di(carbamoylthio)-2-dimethylaminopropane
1,3-bis(carbamoylthio)-2-(n,n-dimethylamino)propane
FT-0658836
s-[3-carbamoylsulfanyl-2-(dimethylamino)propyl] carbamothioate
carbamothioic acid s-[3-(carbamoylthio)-2-(dimethylamino)propyl] ester
A809338
s-[3-aminocarbonylsulfanyl-2-(dimethylamino)propyl] carbamothioate
z45yuy784h ,
unii-z45yuy784h
carbamothioic acid, s,s'-[2-(dimethylamino)-1,3-propanediyl] ester
AKOS015898730
CHEMBL1436987
cartap [iso]
1,3-bis(carbamoylthio)-2-n,n-(dimethylamino)propane
carbamothioic acid sc,sc'-(2-(dimethylamino)-1,3-propanediyl) ester
cartap [mi]
SCHEMBL25918
DTXSID4044165
carbamothioic acid, sc,sc'-[2-(dimethylamino)-1,3-propanediyl] ester
IRUJZVNXZWPBMU-UHFFFAOYSA-N
J-014439
s,s'-2-(dimethylamino)propane-1,3-diyl dicarbamothioate
AMY22830
E78692
s-(3-carbamoylsulfanyl-2-dimethylaminopropyl) aminomethanethioate
cartap 100 microg/ml in methanol
CS-0129008
HY-136395

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"Cartap and cypermethrin, which are among the most widely used pesticides in many countries, are considered safe because of their low mammalian toxicity and their low persistence in the environment."( Aquatic toxicity of cartap and cypermethrin to different life stages of Daphnia magna and Oryzias latipes.
Choi, K; Jung, J; Kim, Y; Oh, S, 2008
)
0.35
" The evaluation of the chorion of the eggshell in this study has clarified the toxic effect of methomyl and cartap hydrochloride on eggs."( Insecticide toxicity to the borer Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae): developmental and egg-laying effects.
Arcanjo, LP; Costa, ÁH; Ferreira, DO; Martins, JC; Picanço, MC; Serrão, JE; Silva, RS; Soares, JRS, 2018
)
0.48
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
nereistoxin analogue insecticide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency79.43280.004023.8416100.0000AID485290
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency50.11870.354828.065989.1251AID504847
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1104204Insecticidal activity against adult female imidacloprid-susceptible Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay2009Pest management science, Nov, Volume: 65, Issue:11
Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.
AID1104200Resistance factor, ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female B-type Bemisia tabaci NJ2009Pest management science, Nov, Volume: 65, Issue:11
Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.
AID1104202Insecticidal activity against adult female imidacloprid-resistant Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioa2009Pest management science, Nov, Volume: 65, Issue:11
Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (55)

TimeframeStudies, This Drug (%)All Drugs %
pre-199010 (18.18)18.7374
1990's2 (3.64)18.2507
2000's17 (30.91)29.6817
2010's16 (29.09)24.3611
2020's10 (18.18)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.94

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.94 (24.57)
Research Supply Index4.03 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.94)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews3 (5.45%)6.00%
Case Studies2 (3.64%)4.05%
Observational0 (0.00%)0.25%
Other50 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]