Page last updated: 2024-11-12

s 1812

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

S 1812: represents dihalopropenyloxybenzene class of insecticides; effective on Lepidoptera & Thysanoptera pests [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11488729
CHEMBL ID2136658
CHEBI ID38887
SCHEMBL ID83386
MeSH IDM0376890

Synonyms (33)

Synonym
179101-81-6
pyridalyl
CHEBI:38887 ,
2-(3-{2,6-dichloro-4-[(3,3-dichloroprop-2-en-1-yl)oxy]phenoxy}propoxy)-5-(trifluoromethyl)pyridine
NCGC00163775-01
s 1812
pyridalyl [iso]
2-(3-(2,6-dichloro-4-((3,3-dichloro-2-propen-1-yl)oxy)phenoxy)propoxy)-5-(trifluoromethyl)pyridine
pyridine, 2-(3-(2,6-dichloro-4-((3,3-dichloro-2-propen-1-yl)oxy)phenoxy)propoxy)-5-(trifluoromethyl)-
unii-qtd92z2p2z
S1812 ,
qtd92z2p2z ,
hsdb 7892
s-1812 ,
pyridine, 2-(3-(2,6-dichloro-4-((3,3-dichloro-2-propenyl)oxy)phenoxy)propoxy)-5-(trifluoromethyl)-
pleo
nocturn
overture
tesoro
pyridalyl [mi]
SCHEMBL83386
3,5-dichloro-1-(3,3-dichloro-2-propenyloxy)-4-[3-(5-trifluoromethylpyridin-2-yloxy)propyloxy]benzene
3,5-di-chloro-1-(3,3-dichloro-2-propenyloxy)-4-[3-(5-trifluoromethylpyridin-2-yloxy)propyl-oxy]benzene
3,5-di-chloro-1-(3,3-dichloro-2-propenyloxy)-4-[3-(5-trifluoromethylpyridin-2-yloxy)propyloxy]benzene
CHEMBL2136658
DTXSID8034875
pyridalyl, pestanal(r), analytical standard
pyridalyl 100 microg/ml in cyclohexane
2-(3-(2,6-dichloro-4-((3,3-dichloroallyl)oxy)phenoxy)propoxy)-5-(trifluoromethyl)pyridine
Q1915098
2-[3-[2,6-dichloro-4-(3,3-dichloroprop-2-enoxy)phenoxy]propoxy]-5-(trifluoromethyl)pyridine
pyridine, 2-[3-[2,6-dichloro-4-[(3,3-dichloro-2-propen-1-yl)oxy]phenoxy]propoxy]-5-(trifluoromethyl)-
AKOS040744697

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" A safe waiting period of 17-18 d after final insecticide application needs to be maintained before harvesting the crop."( Persistence behaviour and safety risk evaluation of pyridalyl in tomato and cabbage.
Barik, SR; Bhattacharyya, A; Ganguly, P; Goon, A; Mandal, J; Patra, S; Samanta, A, 2020
)
0.56
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
organochlorine insecticideAny organochlorine pesticide that has been used as an insecticide.
organofluorine insecticide
dichlorobenzeneAny member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency34.91900.000627.21521,122.0200AID651741; AID720636
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (15)

Assay IDTitleYearJournalArticle
AID1632161Insecticidal activity against Aphis craccivora assessed as mortality at 200 ug/ml pre-incubated with horsebean shoot with aphids for 2 secs and measured 48 hrs post dose by foliar application method2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1112594Insecticidal activity against Plutella xylostella (diamondback moth) third-instar larvae reared on 10 ug/mL compound pre-treated cabbage leaf disks assessed as insect mortality measured after 2 days post compound treatment by leaf dipping method2012Pest management science, Jul, Volume: 68, Issue:7
Design, synthesis, insecticidal activity and structure-activity relationship of 3,3-dichloro-2-propenyloxy-containing phthalic acid diamide structures.
AID1112914Insecticidal activity against third-instar larvae of Plutella xylostella (diamondback moth) fed on compound treated cabbage leaves assessed as mortality at 6.25 mg/l after 3 days relative to control2013Pest management science, May, Volume: 69, Issue:5
Design, synthesis and structure-activity relationship of novel insecticidal dichloro-allyloxy-phenol derivatives containing substituted pyrazol-3-ols.
AID1112915Insecticidal activity against third-instar larvae of Plutella xylostella (diamondback moth) fed on compound treated cabbage leaves assessed as mortality at 25 mg/l after 3 days relative to control2013Pest management science, May, Volume: 69, Issue:5
Design, synthesis and structure-activity relationship of novel insecticidal dichloro-allyloxy-phenol derivatives containing substituted pyrazol-3-ols.
AID1632159Insecticidal activity against Plutella xylostella assessed as mortality at 100 ug/ml pre-incubated with cabbage leaves for 2 to 3 secs and measured 48 hrs post dose by leaf disc assay2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1632162Insecticidal activity against Aphis craccivora assessed as mortality at 100 ug/ml pre-incubated with horsebean shoot with aphids for 2 secs and measured 48 hrs post dose by foliar application method2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1632164Acaricidal activity against Tetranychus cinnabarinus assessed as mortality at 200 ug/ml pre-incubated with mite-infested Sieva bean plants for 3 secs and measured 48 hrs post dose2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1112593Insecticidal activity against Plutella xylostella (diamondback moth) third-instar larvae reared on 10 ug/mL compound pre-treated cabbage leaf disks assessed as insect mortality measured after 3 days post compound treatment by leaf dipping method2012Pest management science, Jul, Volume: 68, Issue:7
Design, synthesis, insecticidal activity and structure-activity relationship of 3,3-dichloro-2-propenyloxy-containing phthalic acid diamide structures.
AID1632166Acaricidal activity against Tetranychus cinnabarinus assessed as mortality at 50 ug/ml pre-incubated with mite-infested Sieva bean plants for 3 secs and measured 48 hrs post dose2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1632160Insecticidal activity against Plutella xylostella assessed as mortality at 50 ug/ml pre-incubated with cabbage leaves for 2 to 3 secs and measured 48 hrs post dose by leaf disc assay2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1112916Insecticidal activity against third-instar larvae of Plutella xylostella (diamondback moth) fed on compound treated cabbage leaves assessed as mortality at 100 mg/l after 3 days relative to control2013Pest management science, May, Volume: 69, Issue:5
Design, synthesis and structure-activity relationship of novel insecticidal dichloro-allyloxy-phenol derivatives containing substituted pyrazol-3-ols.
AID1632165Acaricidal activity against Tetranychus cinnabarinus assessed as mortality at 100 ug/ml pre-incubated with mite-infested Sieva bean plants for 3 secs and measured 48 hrs post dose2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1632158Insecticidal activity against Plutella xylostella assessed as mortality at 200 ug/ml pre-incubated with cabbage leaves for 2 to 3 secs and measured 48 hrs post dose by leaf disc assay2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
AID1112596Insecticidal activity against Plutella xylostella (diamondback moth) third-instar larvae reared on 100 ug/mL compound pre-treated cabbage leaf disks assessed as insect mortality measured after 2 days post compound treatment by leaf dipping method2012Pest management science, Jul, Volume: 68, Issue:7
Design, synthesis, insecticidal activity and structure-activity relationship of 3,3-dichloro-2-propenyloxy-containing phthalic acid diamide structures.
AID1632163Insecticidal activity against Aphis craccivora assessed as mortality at 50 ug/ml pre-incubated with horsebean shoot with aphids for 2 secs and measured 48 hrs post dose by foliar application method2016Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (25)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (24.00)29.6817
2010's11 (44.00)24.3611
2020's8 (32.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 17.22

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index17.22 (24.57)
Research Supply Index3.30 (2.92)
Research Growth Index5.33 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (17.22)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other26 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]