Compounds > 1-naphthalenesulfonic acid
Page last updated: 2024-09-20

1-naphthalenesulfonic acid

Cross-References

ID SourceID
PubMed CID6812
CHEMBL ID1160029
CHEBI ID30895
SCHEMBL ID4323
MeSH IDM0398958

Synonyms (44)

Synonym
AC-18225
AKOS009031607
EN300-19780
.alpha.-naphthalenesulfonic acid
naphthalene-1-sulfonic acid
CHEBI:30895 ,
alpha-naphthalenesulfonic acid
1-naphthalenesulfonic acid
naphthalene-1-sulphonic acid
85-47-2
1-naphthalenesulfonic acid, >50%
68153-01-5
naphthalenesulphonic acid
naphthalenesulfonic acid
pszynbskgubxeh-uhfffaoysa-
inchi=1/c10h8o3s/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7h,(h,11,12,13)
naphthalene-1-sulfonic acid anion
CHEMBL1160029
A841338
1-naphthalenemonosulfonate
einecs 201-610-1
0sjh61wm2j ,
unii-0sjh61wm2j
25155-19-5
unii-vzw67vii75
vzw67vii75 ,
einecs 246-676-2
68412-23-7
FT-0631399
1-sulfonaphthalene
ht-907
1-naphthalenesulfonic acid [mi]
SCHEMBL4323
naphtalenesulfonic acid
naphthalene sulfonic acid
naphthalene-alpha-sulphonic acid
DTXSID7048033
1-naphthyl sulfonic acid
W-109309
mfcd00003987
CS-0238578
Q10395591
4-(5-carboxy-pyridin-2-yl)-piperazine-1-carboxylicacidtert-butylester
C13420

Drug Classes (1)

ClassDescription
naphthalenesulfonic acid
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Choline O-acetyltransferaseHomo sapiens (human)Ki1,600.00000.10001.30003.0000AID52124
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (4)

Processvia Protein(s)Taxonomy
phosphatidylcholine biosynthetic processCholine O-acetyltransferaseHomo sapiens (human)
neurotransmitter transportCholine O-acetyltransferaseHomo sapiens (human)
neuromuscular synaptic transmissionCholine O-acetyltransferaseHomo sapiens (human)
acetylcholine biosynthetic processCholine O-acetyltransferaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (1)

Processvia Protein(s)Taxonomy
choline O-acetyltransferase activityCholine O-acetyltransferaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (5)

Processvia Protein(s)Taxonomy
nucleusCholine O-acetyltransferaseHomo sapiens (human)
cytosolCholine O-acetyltransferaseHomo sapiens (human)
synapseCholine O-acetyltransferaseHomo sapiens (human)
cytoplasmCholine O-acetyltransferaseHomo sapiens (human)
neuron projectionCholine O-acetyltransferaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID52124Inhibition of choline acetyltransferase isolated from squid head ganglia1981Journal of medicinal chemistry, Dec, Volume: 24, Issue:12
Interaction of aromatic dyes with the coenzyme A binding site of choline acetyltransferase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
1-anilino-8-naphthalenesulfonate[no description available]medium20aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
nadp[no description available]medium10NADPfundamental metabolite
nad[no description available]medium10NADgeroprotector
adenosine monophosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
congo red[no description available]medium10bis(azo) compound
coenzyme a[no description available]medium10adenosine 3',5'-bisphosphatecoenzyme;
Escherichia coli metabolite;
mouse metabolite
5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate)[no description available]medium10
adenosine 3'-phosphate-5'-phosphate[no description available]medium10adenosine bisphosphateEscherichia coli metabolite;
mouse metabolite
Reactive blue 2[no description available]medium10anthraquinone
2-anilinonaphthalene-6-sulfonic acid[no description available]medium10
oxazoles[no description available]medium101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
2-naphthalenesulfonic acid[no description available]medium10naphthalenesulfonic acidenvironmental contaminant;
xenobiotic
imidacloprid[no description available]medium10imidacloprid;
imidazolidines;
monochloropyridine		environmental contaminant;
genotoxin;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic
bromosuccinimide[no description available]medium10dicarboximide;
organobromine compound;
pyrrolidinone		reagent
guanidine[no description available]medium10carboxamidine;
guanidines;
one-carbon compound
acrylamide[no description available]medium10acrylamides;
N-acylammonia;
primary carboxamide		alkylating agent;
carcinogenic agent;
Maillard reaction product;
mutagen;
neurotoxin
suramin[no description available]low00naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
1-naphthylamine-5-sulfonic acid[no description available]low00naphthalenesulfonic acid
1-amino-2-naphthol-4-sulfonic acid[no description available]low00aminonaphthalene;
naphthalenesulfonic acid		mutagen
naphthol yellow[no description available]low00C-nitro compound;
naphthalenesulfonic acid;
naphthols		histological dye
chromotropic acid[no description available]low00naphthalenediols;
naphthalenesulfonic acid		indicator
reactive red 120 dye[no description available]low00azobenzenes;
bis(azo) compound;
chloro-1,3,5-triazine;
diamino-1,3,5-triazine;
naphthalenesulfonic acid		dye
ponceau mx[no description available]low00azobenzenes;
naphthalenesulfonic acid;
naphthols		carcinogenic agent;
cardiotoxic agent
ConditionIndicatedRelationship StrengthStudiesTrials
Angiogenesis, Pathologic0low10
Angiogenesis, Pathological0low10
Animal Mammary Carcinoma0low10
Benign Neoplasms0low10
Benign Neoplasms, Brain0low10
Bone Marrow Diseases0low10
Brain Cancer0low10
Brain Metastases0low10
Brain Neoplasm, Primary0low10
Brain Neoplasms0low10
Brain Neoplasms, Benign0low10
Brain Neoplasms, Malignant0low10
Brain Neoplasms, Malignant, Primary0low10
Brain Neoplasms, Primary Malignant0low10
Brain Tumor, Primary0low10
Brain Tumor, Recurrent0low10
Brain Tumors0low10
Cancer0low10
Cancer of Brain0low10
Cancer of the Brain0low10
Enlarged Spleen0low10
Experimental Lung Inflammation0low10
Experimental Mammary Neoplasms0low10
Experimental Neoplasms0low10
Glial Cell Tumors0low10
Glioma0low10
Intracranial Neoplasms0low10
Lobar Pneumonia0low10
Lung Inflammation0low10
Malignancy0low10
Malignant Glioma0low10
Malignant Neoplasms0low10
Malignant Neoplasms, Brain0low10
Malignant Primary Brain Neoplasms0low10
Malignant Primary Brain Tumors0low10
Mammary Carcinoma, Animal0low10
Mammary Neoplasms0low10
Mammary Neoplasms, Animal0low10
Mammary Neoplasms, Experimental0low10
Mixed Glioma0low10
Neoplasia0low10
Neoplasm0low10
Neoplasms0low10
Neoplasms, Benign0low10
Neoplasms, Brain0low10
Neoplasms, Brain, Benign0low10
Neoplasms, Brain, Malignant0low10
Neoplasms, Brain, Primary0low10
Neoplasms, Experimental0low10
Neoplasms, Experimental Mammary0low10
Neoplasms, Intracranial0low10
Neoplasms, Mammary0low10
Neovascularization, Pathologic0low10
Neovascularization, Pathological0low10
Nephritis0low10
Pathologic Angiogenesis0low10
Pathologic Neovascularization0low10
Pneumonia0low10
Pneumonia, Lobar0low10
Pneumonitis0low10
Primary Brain Neoplasms0low10
Primary Malignant Brain Neoplasms0low10
Primary Malignant Brain Tumors0low10
Pulmonary Inflammation0low10
Splenomegaly0low10
Tumors0low10