Page last updated: 2024-11-05

dienochlor

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dienochlor: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16686
CHEMBL ID1355965
CHEBI ID81753
SCHEMBL ID117767
MeSH IDM0046927

Synonyms (69)

Synonym
bi-2,4-cyclopentadien-1-yl, 1,1',2,2',3,3',4,4',5,5'-decachloro-
nsc-41880
nsc41880
hrs 16
wln: l5 ahj ag bg cg dg eg a- al5 ahj ag bg cg dg eg
pentac
2227-17-0
bis(pentachlorocyclopentadienyl)
dienochlor
hooker hrs 1654
decachlor
hooker hrs-16
decachlorobis(2,4-cyclopentadiene-1-yl)
hrs 16a
hrs 1654
ent 25,718
nsc26106
decachlorobi-2,4-cyclopentadiene-1-yl
pentac sp
decachlorobi-2,4-cyclopentadien-1-yl
bi-2, 1,1',2,2',3,3',4,4',5,5'-decachloro-
bis(pentachlor-2,4-cyclopentadien-1-yl)
pentac wp
bis(pentachloro-2,4-cyclopentadien-1-yl)
nsc-26106
bi-2, decachloro-
perchloro-1,1'-bicyclopenta-2,4-dienyl
perchloro-1,1'-bicyclopenta-2,4-diene
hsdb 1557
nsc 41880
epa pesticide chemical code 027501
ccris 9112
1,1',2,2',3,3',4,4',5,5'-decachlorobi-2,4-cyclopentadien-1-yl
nsc 26106
pentac (50wp)
bi-2,4-cyclopentadien-1-yl, decachloro-
brn 2064747
dienochlore
caswell no. 274
dienochlor [bsi:iso]
decachlorobis(2,4-cyclopentadien-1-yl)
ai3-25718
einecs 218-763-5
hrs-16
dienochlore [iso-french]
NCGC00166129-01
1,2,3,4,5-pentachloro-5-(1,2,3,4,5-pentachlorocyclopenta-2,4-dien-1-yl)cyclopenta-1,3-diene
C18446
4-05-00-01542 (beilstein handbook reference)
243z2svz40 ,
unii-243z2svz40
FT-0634148
AKOS015903347
chebi:81753 ,
CHEMBL1355965
SCHEMBL117767
dienochlor [iso]
hrs-1654
hrs-16a
dienochlor [mi]
dienochlor [hsdb]
pentac aquaflow
LWLJUMBEZJHXHV-UHFFFAOYSA-N
DTXSID9032371
dienochlor, pestanal(r), analytical standard
J-014617
Q3032700
perchloro-1,1'-bi(cyclopenta-2,4-diene)
perchloro-[1,1'-bi(cyclopentane)]-2,2',4,4'-tetraene

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The compounds were tested at their respective maximum field recommended concentration (MFRC), and, when strong lethal effects were observed, a dose-response assay with a dilution series of the MFRC was undertaken to calculate LC(50) values."( Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
Besard, L; Cuvelier, X; Mommaerts, V; Smagghe, G; Sterk, G; Vandeven, J, 2010
)
0.36
" For oral exposures via treated sugar water, the dose-response assay showed the LC(50) values for abamectin, bifenazate, bifenthrin and etoxazole to be 1/15 MFRC (1."( Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
Besard, L; Cuvelier, X; Mommaerts, V; Smagghe, G; Sterk, G; Vandeven, J, 2010
)
0.36
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
organochlorine compoundAn organochlorine compound is a compound containing at least one carbon-chlorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (10)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency11.22020.003245.467312,589.2998AID2517
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency17.74070.140911.194039.8107AID2451
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency31.62280.125919.1169125.8920AID2549
phosphopantetheinyl transferaseBacillus subtilisPotency17.78280.141337.9142100.0000AID1490
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency2.51190.016525.307841.3999AID602332
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency3.16230.354828.065989.1251AID504847
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency51.20870.010039.53711,122.0200AID1469; AID1479
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency7.99600.00798.23321,122.0200AID2546; AID2551
DNA polymerase kappa isoform 1Homo sapiens (human)Potency6.70160.031622.3146100.0000AID588579
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency39.81070.251215.843239.8107AID504327
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID1104386Toxicity against worker Bombus terrestris (bumblebee) assessed as reduction in reproduction at 500 mg a.i./l, po administered through sugar water for 11 weeks measured once a week for 11 weeks relative to control2010Pest management science, Jul, Volume: 66, Issue:7
Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
AID1104375Toxicity against worker Bombus terrestris (bumblebee) assessed as reduction in reproduction at 500 mg a.i./l, po administered through pollen for 11 weeks measured once a week for 11 weeks2010Pest management science, Jul, Volume: 66, Issue:7
Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
AID1104481Contact toxicity against worker Bombus terrestris (bumblebee) assessed as mortality at 500 mg a.i./l applied on the dorsal thorax for 11 weeks measured everyday for 3 days followed by once a week for 11 weeks2010Pest management science, Jul, Volume: 66, Issue:7
Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
AID1104410Contact toxicity against worker Bombus terrestris (bumblebee) assessed as reduction in reproduction at 500 mg a.i./l applied on the dorsal thorax for 11 weeks measured once a week for 11 weeks relative to control2010Pest management science, Jul, Volume: 66, Issue:7
Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
AID1104455Toxicity against worker Bombus terrestris (bumblebee) assessed as mortality at 500 mg a.i./l, po administered through sugar water for 11 weeks measured everyday for 3 days followed by once a week for 11 weeks2010Pest management science, Jul, Volume: 66, Issue:7
Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
AID1104433Toxicity against worker Bombus terrestris (bumblebee) assessed as mortality at 500 mg a.i./l, po administered through pollen for 11 weeks measured everyday for 3 days followed by once a week for 11 weeks2010Pest management science, Jul, Volume: 66, Issue:7
Compatibility of traditional and novel acaricides with bumblebees (Bombus terrestris): a first laboratory assessment of toxicity and sublethal effects.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.38

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.38 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.54 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.38)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]