| Assay ID | Title | Year | Journal | Article |
|---|
| AID1248416 | Drug metabolism in yeast cells expressing human CYP3A4 assessed as human CYP3A4-mediated metabolite-M4 formation by measuring compound production ratio at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1091174 | Stomach toxicity against Mythimna separata (Oriental armyworm) fourth-instar larvae reared on compound pre-treated corn leaves assessed as insect mortality at 10 mg/kg measured 4 days post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID506706 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in HEK293 cells transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 ( | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1248426 | Selectivity index, ratio of Km for human CYP2C19-mediated metabolite-M1 formation to Km for human CYP3A4-mediated metabolite-M1 formation | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1111837 | Binding affinity to Chironomus tentans EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1081285 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 10 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
| Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1248422 | Drug metabolism in yeast cells expressing human CYP3A4 assessed as human CYP3A4-mediated metabolite-M1 formation at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID506695 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeas | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1081851 | Insecticidal activity against Culex pipiens pallens (mosquito) fourth-instar larvae assessed as insect mortality at 2 ug/mL measured 96 hr post compound exposure | 2011 | Journal of agricultural and food chemistry, Jan-26, Volume: 59, Issue:2
| Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles. |
| AID1111827 | Binding affinity to Myzus persicae EcR (green peach aphid) | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1081284 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 5 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
| Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1112677 | Insecticidal activity against Bactrocera oleae assessed as insect mortality at 180 mg Ai/L applied through residual contact on glass surfaces measured after 15 days (Rvb = 45.8 +/- 16.3%) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID288184 | Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11
| QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1081853 | Insecticidal activity against Plutella xylostella (diamondback moth) second-instar larvae grown on compound treated fresh cabbage leaves assessed as insect mortality at 200 ug/mL measured 96 hr post compound exposure by leaf film feeding method | 2011 | Journal of agricultural and food chemistry, Jan-26, Volume: 59, Issue:2
| Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles. |
| AID1248424 | Drug metabolism in yeast cells expressing human CYP2C19 assessed as human CYP2C19-mediated metabolite-M1 formation at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1081850 | Insecticidal activity against Plutella xylostella (diamondback moth) second-instar larvae grown on compound treated fresh cabbage leaves assessed as insect mortality measured 96 hr post compound exposure by leaf film feeding method | 2011 | Journal of agricultural and food chemistry, Jan-26, Volume: 59, Issue:2
| Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles. |
| AID1111833 | Binding affinity to Locusta migratoria ecdysone receptor (EcR) | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID506705 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in HEK293 cells transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 ( | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1111844 | Displacement of [3H]PonA from recombinant Nezara viridula EcR11 | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1719918 | Drug metabolism in microsomes containing baculovirus expressing human CYP3A4 assessed as CYP3A4-mediated hydroxylation at t-butyl group at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis relative to c | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID506699 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeas | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1248425 | Drug metabolism in yeast cells expressing human CYP2C19 assessed as human CYP2C19-mediated metabolite-M1 formation per mol of protein at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID506709 | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606)-mediated mylz2 gene expression expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivato | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1091956 | Apparent hydrophobicity, log D of the compound in Octanol-buffer | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7
| Importance of physicochemical properties for the design of new pesticides. |
| AID1306283 | Inhibition of human P-glycoprotein transfected in pig LLC-GA5-COL150 cells assessed as quinidine transport from apical to basolateral side preincubated for 30 mins followed by quinidine addition to apical side measured after 60 mins | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14
| Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. |
| AID506694 | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606)-mediated myl7 gene expression expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1090840 | Stomach toxicity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 5 mg/kg at 25+/-1 degC measured after 4 days | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1091172 | Stomach toxicity against Mythimna separata (Oriental armyworm) fourth-instar larvae reared on compound pre-treated corn leaves assessed as insect mortality at 2.5 mg/kg measured 4 days post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID1080454 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 10 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1111377 | Larvicidal activity against Spodoptera littoralis assessed as mortality applied topically after 1 week | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1111388 | Agonist activity at ecdysone receptor in Spodoptera littoralis Sl2 cells after 24 hr by luciferase reporter gene assay | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID288192 | Partition coefficient, log P of the compound | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11
| QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1248415 | Drug metabolism in yeast cells expressing human CYP3A4 assessed as human CYP3A4-mediated metabolite-M3 formation by measuring compound production ratio at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID506690 | Toxicity in zebrafish AB embryos assessed as induction of patterning deffects at 10 uM single dose measured 72 hrs post fertilization | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1112683 | Insecticidal activity against Bactrocera oleae assessed as insect survival lifespan at 180 mg Ai/L applied through oral ingestion (Rvb = 79.7 +/- 12.2 days) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID1081848 | Insecticidal activity against Culex pipiens pallens (mosquito) fourth-instar larvae assessed as insect mortality at 0.5 ug/mL measured 96 hr post compound exposure | 2011 | Journal of agricultural and food chemistry, Jan-26, Volume: 59, Issue:2
| Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles. |
| AID1080450 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 30 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1111832 | Binding affinity to Anthonomus grandis ecdysone receptor (EcR) | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1090835 | Contact toxicity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) assessed as mortality at 25 +/-1 degC applied topically on the thoracic tergite measured per larva after 96 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1719950 | Drug metabolism in microsomes containing baculovirus expressing human CYP1A2 assessed as CYP1A2-mediated hydroxylation at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1112685 | Insecticidal activity against Bactrocera oleae assessed as insect mortality at 180 mg Ai/L applied through oral ingestion measured after 15 days (Rvb = 2.5 +/- 2.5%) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID1111385 | Selectivity ratio of EC50 for ecdysone receptor in Bombyx mori Bm5 cells to EC50 for ecdysone receptor in Spodoptera littoralis Sl2 cells | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1111391 | Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1111840 | Binding affinity to Chilo suppressalis (rice stem borer) EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1719917 | Drug metabolism in microsomes containing baculovirus expressing human CYP3A4 assessed as CYP3A4-mediated hydroxylation at ethyl-CH2 group of B-ring at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis r | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1111830 | Binding affinity to Nezara viridula EcR11 | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1090832 | Toxic ratio of RH-5992 LD90 to compound LD90 for fourth-instar larval stage of Mythimna separata (Oriental armyworm) measured after 96 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1081849 | Insecticidal activity against Culex pipiens pallens (mosquito) fourth-instar larvae assessed as insect mortality at 1 ug/mL measured 96 hr post compound exposure | 2011 | Journal of agricultural and food chemistry, Jan-26, Volume: 59, Issue:2
| Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles. |
| AID1111603 | Agonist activity at ecdysone receptor in Drosophila melanogaster S2 cells at 10 uM after 24 hr by luciferase reporter gene assay relative to 20-hydroxyecdysone | 2010 | Pest management science, Nov, Volume: 66, Issue:11
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. |
| AID1248419 | Drug metabolism in yeast cells expressing human CYP2C19 assessed as human CYP2C19-mediated metabolite-M5 formation by measuring compound production ratio at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1080458 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 200 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1111836 | Binding affinity to Lucilia cuprina EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1112689 | Insecticidal activity against Bactrocera oleae assessed as insect mortality at 180 mg Ai/L applied through oral ingestion measured after 24 hr (Rvb = 0%) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID1091168 | Contact toxicity against Ostrinia furnacalis (Asian corn borer) fourth-instar larvae exposed to compound on thoracic tergite region assessed as insect mortality measured 48 hr post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID1091958 | Hydrophobicity, log P of the compound in octanol-water by shaking-flask method | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7
| Importance of physicochemical properties for the design of new pesticides. |
| AID1111606 | Agonist activity at ecdysone receptor in Drosophila melanogaster S2 cells after 24 hr by luciferase reporter gene assay | 2010 | Pest management science, Nov, Volume: 66, Issue:11
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. |
| AID288191 | Membrane retention in permeability experiment with artificial membrane | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11
| QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1080457 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 100 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1091955 | Dissociation constant, pKa of the compound at pH 7.3 | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7
| Importance of physicochemical properties for the design of new pesticides. |
| AID1080453 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 5 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1091170 | Contact toxicity against Spodoptera litura fourth-instar larvae exposed to compound on thoracic tergite region assessed as insect mortality measured 48 hr post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID1719916 | Drug metabolism in microsomes containing baculovirus expressing human CYP3A4 assessed as CYP3A4-mediated hydroxylation at methyl group of A-ring at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis rela | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1111834 | Binding affinity to Leptinotarsa decemlineata EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1111596 | Ratio of EC50 for EcR in Drosophila melanogaster S2 cells to EC50 for EcR in Bombyx mori Bm5 cells | 2010 | Pest management science, Nov, Volume: 66, Issue:11
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. |
| AID1248417 | Drug metabolism in yeast cells expressing human CYP2C19 assessed as human CYP2C19-mediated metabolite-M1 formation by measuring compound production ratio at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1091957 | Apparent permeability of the compound by PAMPA | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7
| Importance of physicochemical properties for the design of new pesticides. |
| AID1091171 | Stomach toxicity against Spodoptera litura third-instar larvae reared on compound pre-treated cabbage leaves assessed as insect mortality measured 3 days post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID1090831 | Toxic ratio of RH-5992 LD50 to compound LD50 for fourth-instar larval stage of Spodoptera litura measured after 48 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID506697 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeas | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1248427 | Selectivity index, ratio of Vmax for human CYP3A4-mediated metabolite-M1 formation to Vmax for human CYP2C19-mediated metabolite-M1 formation | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1081281 | Insecticidal activity against apterous adult stage of Aphis fabae (black bean aphids) in soybean tender shoots assessed as induction of premature, abnormal and lethal larva moult at 10 mg/l treated for 5 secs measured after 3 days by modified FAO dip test | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
| Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID506707 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in HEK293 cells transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 ( | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1111835 | Binding affinity to Drosophila melanogaster EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1248414 | Drug metabolism in yeast cells expressing human CYP3A4 assessed as human CYP3A4-mediated metabolite-M1 formation by measuring compound production ratio at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1112687 | Insecticidal activity against Bactrocera oleae assessed as insect mortality at 180 mg Ai/L applied through oral ingestion measured after 7 days (Rvb = 2.5 +/- 2.5%) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID506692 | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimer | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1090839 | Stomach toxicity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 2.5 mg/kg at 25+/-1 degC measured after 4 days | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1111595 | Cytotoxicity against Drosophila melanogaster S2 cells at 10 to 100 uM after 24 hr by CellTiter assay | 2010 | Pest management science, Nov, Volume: 66, Issue:11
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. |
| AID1090830 | Contact toxicity against fourth-instar larval stage of Ostrinia furnacalis (Asian corn borer) assessed as mortality at 25 +/-1 degC applied topically on the thoracic tergite measured per gm of larva after 48 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID506708 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in HEK293 cells transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 ( | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1090838 | Stomach toxicity against third-instar larval stage of Spodoptera exigua in cabbage leaves assessed as mortality at 25 +/-1 degC treated for 3 secs before larval infestation measured after 3 days by leaf-dip method | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1719922 | Drug metabolism in microsomes containing baculovirus expressing human CYP2D6 assessed as CYP2D6-mediated hydroxylation at ethyl-CH2 group of B-ring at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis r | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1248423 | Drug metabolism in yeast cells expressing human CYP3A4 assessed as human CYP3A4-mediated metabolite-M1 formation per mol of protein at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1090841 | Stomach toxicity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 10 mg/kg at 25+/-1 degC measured after 4 days | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1111828 | Binding affinity to Bemisia tabaci (sweet potato whitefly) ecdysone receptor (EcR) | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1111389 | Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay relative to tebufenozide | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1080449 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 20 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID506691 | Toxicity in zebrafish AB embryos assessed as induction of patterning deffects at 10 uM dosed every 24 hrs measured 72 hrs post fertilization | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1111376 | Ratio of LD50 for Spodoptera littoralis to LD50 for Bombyx mori | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1112679 | Insecticidal activity against Bactrocera oleae assessed as insect mortality at 180 mg Ai/L applied through residual contact on glass surfaces measured after 7 days (Rvb = 4.0 +/- 4.0%) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID1111843 | Displacement of [3H]PonA from recombinant Nezara viridula EcR10 | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID506696 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeas | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1080447 | Toxic ratio of RH-5992 LC50 to compound LC50 for second-instar larval stage of Plutella xylostella (diamondback moth) measured after 6 days by leaf-dip method | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1306285 | Lipophilicity logP of the compound | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14
| Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. |
| AID1090828 | Toxic ratio of RH-5992 LD50 to compound LD50 for fourth-instar larval stage of Ostrinia furnacalis (Asian corn borer) measured after 48 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID506701 | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimer | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1111378 | Larvicidal activity against Bombyx mori assessed as mortality applied topically after 1 week | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1248418 | Drug metabolism in yeast cells expressing human CYP2C19 assessed as human CYP2C19-mediated metabolite-M2 formation by measuring compound production ratio at 200 uM pre-incubated for 2 mins at 37 degC before NADPH addition by LC/MS method | 2015 | Bioorganic & medicinal chemistry, Oct-15, Volume: 23, Issue:20
| Identification and in silico prediction of metabolites of the model compound, tebufenozide by human CYP3A4 and CYP2C19. |
| AID1112039 | Insecticidal activity against third-instar larvae of fufenozide-resistant Plutella xylostella (diamondback moth) assessed as mortality by leaf-dip bioassay method | 2012 | Pest management science, Feb, Volume: 68, Issue:2
| Cross-resistance patterns and fitness in fufenozide-resistant diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae). |
| AID1111386 | Agonist activity at ecdysone receptor in Spodoptera littoralis Sl2 cells after 24 hr by luciferase reporter gene assay relative to tebufenozide | 2010 | Pest management science, May, Volume: 66, Issue:5
| Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. |
| AID1090827 | Toxic ratio of RH-5992 LD50 to compound LD50 for fourth-instar larval stage of Helicoverpa armigerameasured after 48 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1111600 | Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay | 2010 | Pest management science, Nov, Volume: 66, Issue:11
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. |
| AID506704 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in HEK293 cells transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 ( | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID506702 | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimer | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1091173 | Stomach toxicity against Mythimna separata (Oriental armyworm) fourth-instar larvae reared on compound pre-treated corn leaves assessed as insect mortality at 5 mg/kg measured 4 days post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID1080456 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 50 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1111599 | Agonist activity at ecdysone receptor in Drosophila melanogaster B2 cells assessed as reduction in cell density | 2010 | Pest management science, Nov, Volume: 66, Issue:11
| Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. |
| AID1112038 | Insecticidal activity against third-instar larvae of fufenozide-susceptible Plutella xylostella (diamondback moth) assessed as mortality by leaf-dip bioassay method | 2012 | Pest management science, Feb, Volume: 68, Issue:2
| Cross-resistance patterns and fitness in fufenozide-resistant diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae). |
| AID1081283 | Insecticidal activity against apterous adult stage of Aphis fabae ( black bean aphids) in soybean tender shoots assessed as death rate at 200 mg/l treated for 5 secs measured after 48 hr by modified FAO dip test | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
| Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1112681 | Insecticidal activity against Bactrocera oleae assessed as insect mortality at 180 mg Ai/L applied through residual contact on glass surfaces measured after 24 hr (Rvb = 2.0 +/- 2.0%) | 2013 | Pest management science, Jan, Volume: 69, Issue:1
| Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. |
| AID506700 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeas | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID506693 | Induction of nuclear translocation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator compo | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1080448 | Larvicidal activity against second-instar larval stage of Plutella xylostella (diamondback moth) in cabbage leaves assessed as mortality at 25 +/-1 degC treated for 15 secs before larval infestation measured after 6 days by leaf-dip method | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1111838 | Binding affinity to Aedes aegypti EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1111839 | Binding affinity to Plodia interpunctella (Indian meal moth ) EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1090837 | Toxic ratio of RH-5992 LC90 to compound LC90 for third-instar larval stage of Spodoptera exigua measured after 3 days by leaf-dip method | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID313184 | Larvicidal activity against Oriental armyworm | 2008 | Bioorganic & medicinal chemistry, Jan-01, Volume: 16, Issue:1
| Synthesis and insecticidal evaluation of novel N'-tert-butyl-N'-substitutedbenzoyl-N-5-chloro-6-chromanecarbohydrazide derivatives. |
| AID1111842 | Binding affinity to Choristoneura fumiferana EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1080452 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 2.5 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID288189 | Permeability from basolateral to apical side of the Caco-2 cell membrane | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11
| QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1090833 | Contact toxicity against fourth-instar larval stage of Spodoptera litura assessed as mortality at 25 +/-1 degC applied topically on the thoracic tergite measured per gm of larva after 48 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID288188 | Permeability from apical to basolateral side of the Caco-2 cell membrane | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11
| QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1112037 | Resistance ratio, ratio of LC50 for third-instar larvae of fufenozide-resistant Plutella xylostella (diamondback moth) to LC50 for third-instar larvae of fufenozide-susceptible Plutella xylostella | 2012 | Pest management science, Feb, Volume: 68, Issue:2
| Cross-resistance patterns and fitness in fufenozide-resistant diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae). |
| AID1090834 | Toxic ratio of RH-5992 LD50 to compound LD50 for fourth-instar larval stage of Mythimna separata (Oriental armyworm) measured after 96 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1719920 | Drug metabolism in microsomes containing baculovirus expressing human CYP2C9 assessed as CYP2C9-mediated hydroxylation at ethyl-CH2 group of B-ring at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis r | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1111829 | Binding affinity to Nezara viridula EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1090829 | Contact toxicity against fourth-instar larval stage of Helicoverpa armigeraassessed as mortality at 25 +/-1 degC applied topically on the thoracic tergite measured per gm of larva after 48 hr | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID506698 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeas | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1111831 | Binding affinity to Nezara viridula EcR10 | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1719919 | Drug metabolism in microsomes containing baculovirus expressing human CYP2C9 assessed as CYP2C9-mediated hydroxylation at methyl group of A-ring at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis rela | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1719921 | Drug metabolism in microsomes containing baculovirus expressing human CYP2C19 assessed as CYP2C19-mediated hydroxylation at ethyl-CH2 group of B-ring at 200 uM preincubated for 2 mins followed by NADPH addition and measured after 1 hr by LC/MS/MS analysis | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9
| Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms. |
| AID1091169 | Contact toxicity against Helicoverpa armigerafourth-instar larvae exposed to compound on thoracic tergite region assessed as insect mortality measured 48 hr post compound treatment | 2008 | Journal of agricultural and food chemistry, Jul-09, Volume: 56, Issue:13
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives. |
| AID506703 | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in HEK293 cells transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 ( | 2007 | Nature chemical biology, Mar, Volume: 3, Issue:3
| Small-molecule regulation of zebrafish gene expression. |
| AID1090836 | Toxic ratio of RH-5992 LC50 to compound LC50 for third-instar larval stage of Spodoptera exigua measured after 3 days by leaf-dip method | 2007 | Journal of agricultural and food chemistry, Nov-14, Volume: 55, Issue:23
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives. |
| AID1080451 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 40 mg/kg at 25 +/-1 degC measured after 4 days | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22
| Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives. |
| AID1111841 | Binding affinity to Heliothis virescens (tobacco budworm) EcR | 2011 | Pest management science, Nov, Volume: 67, Issue:11
| Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. |
| AID1306282 | Inhibition of human P-glycoprotein transfected in pig LLC-GA5-COL150 cells assessed as quinidine transport from apical to basolateral side at 30 uM preincubated for 30 mins followed by quinidine addition to apical side measured after 60 mins | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14
| Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |