Page last updated: 2024-10-27

fluorouracil and Anal Cancer

fluorouracil has been researched along with Anal Cancer in 425 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Although chemoradiation using 5-fluorouracil (5-FU) and mitomycin-C (MMC) is the standard of care in the treatment of anal cancer, many patients are unable to tolerate MMC."9.15Long-term follow-up of a Phase II trial of high-dose radiation with concurrent 5-fluorouracil and cisplatin in patients with anal cancer (ECOG E4292). ( Benson, AB; Catalano, PJ; Chakravarthy, AB; Mansour, EG; Martenson, JA; Mondschein, JK; Talamonti, MS; Wagner, H, 2011)
"A prospective clinical trial was performed to assess the response and toxicity associated with the use of high dose radiation therapy, 5-fluorouracil, and cisplatin in patients with anal cancer."9.08Initial results of a phase II trial of high dose radiation therapy, 5-fluorouracil, and cisplatin for patients with anal cancer (E4292): an Eastern Cooperative Oncology Group study. ( Benson, AB; Kaplan, EH; Lipsitz, SR; Mansour, EG; Martenson, JA; Otteman, LA; Schuchter, LM; Talamonti, MS; Wagner, H, 1996)
"Our trial shows that the standard treatment for most patients with epidermoid anal cancer should be a combination of radiotherapy and infused 5-fluorouracil and mitomycin, with surgery reserved for those who fall on this regimen."9.08Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research. ( , 1996)
"Standard treatment for locally advanced anal cancer is chemoradiotherapy with mitomycin C and fluorouracil."8.95Capecitabine in locally advanced anal cancer, do we need randomised evidence? ( Chong, LC; Healey, T; Michele, T; Price, TJ, 2017)
"To obtain safety and preliminary efficacy data of the combination of ADXS11-001, live attenuated Listeria monocytogenes bacterium, with mitomycin, 5-fluorouracil (5-FU), and intensity modulated radiation therapy in locally advanced anal cancer."7.88Tolerability of ADXS11-001 Lm-LLO Listeria-Based Immunotherapy With Mitomycin, Fluorouracil, and Radiation for Anal Cancer. ( Barth, P; DiPetrillo, TA; Klipfel, A; Leonard, KL; Mantripragada, K; Oldenburg, N; Perez, K; Rajdev, L; Rosati, K; Roth, L; Safran, H; Schechter, S; Shah, N; Sheng, IY; Vrees, M, 2018)
"Fulminant myocarditis is a rare but potentially life-threatening illness caused by 5-fluorouracil cardiotoxicity."7.83Rapid Extracorporeal Membrane Oxygenation Overcomes Fulminant Myocarditis Induced by 5‑Fluorouracil. ( Amraotkar, AR; DeFilippis, AP; Grubb, KJ; Pachika, A, 2016)
"Five patients with primary colorectal adenocarcinoma or anal squamous cell carcinoma were started on a 2-weeks-on, 1-week-off capecitabine dosing regimen in addition to other chemotherapeutic agents and/or radiation."7.78Capecitabine-induced chest pain relieved by diltiazem. ( Ambrosy, AP; Fisher, GA; Kunz, PL; Witteles, RM, 2012)
"Myocardial ischemia induced by 5-fluorouracil (5-FU) is a relatively rare, but potentially serious, occurrence."7.70Failure of oral nitrate and calcium channel blocker therapy to prevent 5-fluorouracil-related myocardial ischemia: a case report. ( Akpek, G; Hartshorn, KL, 1999)
"The MTDs were determined as 5FU 800 mg/m(2) on RT days 1-4 and 29-32 and MMC 8 mg/m(2) on days 1 and 29 when combined with IMRT/VMAT with SIB and cetuximab in locally advanced anal cancer."6.80Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer. ( Gunnlaugsson, A; Guren, MG; Johnsson, A; Leon, O; Radu, C, 2015)
"Anal cancer is an increasing issue in HIV-positive men who have sex with men (MSM)."6.78Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial. ( de Vries, HJ; Dijkgraaf, MG; Prins, JM; Richel, O; van Noesel, CJ, 2013)
"To assess the feasibility and activity of radio-chemotherapy with mitomycin C (MMC) and cisplatin (CDDP) in locally advanced squamous cell anal carcinoma with reference to radiotherapy (RT) combined with MMC and fluorouracil (5-FU)."6.74Mitomycin C with continuous fluorouracil or with cisplatin in combination with radiotherapy for locally advanced anal cancer (European Organisation for Research and Treatment of Cancer phase II study 22011-40014). ( Bosset, JF; Collette, L; Haustermans, K; Koswig, S; Maingon, P; Matzinger, O; Mineur, L; Mueller, RP; Radosevic-Jelic, L; Roelofsen, F; Van Der Steen-Banasik, EM; Van Houtte, P, 2009)
"Squamous cell cancer of the anal canal (anal cancer) is a rare disease but with worldwide increasing incidence."5.37Single-agent paclitaxel in advanced anal cancer after failure of cisplatin and 5-fluorouracil chemotherapy. ( Abbas, A; Fakih, M; Nehme, E, 2011)
"Anal cancer is the first tumour in which chemoradiotherapy with the intent of organ preservation has largely replaced surgery and is an interesting model of modern multimodal oncological treatment."5.33Chemoradiotherapy of anal cancer is feasible in elderly patients: treatment results of mitomycin-5-FU combined with radiotherapy at Helsinki University Central Hospital 1992-2003. ( Arponen, P; Blomqvist, C; Saarilahti, K; Tenhunen, M; Vaalavirta, L, 2006)
"To measure co-expression of EGFR and Ki67 proteins in pretreatment tumor biopsies of anal cancer patients enrolled on NRG Oncology RTOG 9811, a phase III trial comparing 5-fluorouracil/mitomycin-C/radiation therapy (Arm A) versus 5-fluorouracil/cisplatin/radiation therapy (Arm B), and to correlate expression with clinical outcome."5.24Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811. ( Ajani, JA; Becker, MJ; Berk, LB; Crane, CH; Doll, CM; Ellis, RJ; Grisell, DL; Guha, C; Ho, CK; Kachnic, LA; Klimowicz, A; Kornaga, EN; Lees-Miller, SP; Magliocco, AM; Marsa, GW; Moughan, J; Okawara, GS; Roof, KS; Sperduto, PW, 2017)
"Patients with SCC of anal cancer T2-4N0M0 or T (any) N1-3M0, with good performance status and normal blood and renal function, were treated with capecitabine 825 mg/m(2) bid during radiotherapy associated with a single dose of mitomycin 15 mg/m(2) on day 1."5.22Phase II Study of Capecitabine in Substitution of 5-FU in the Chemoradiotherapy Regimen for Patients with Localized Squamous Cell Carcinoma of the Anal Canal. ( Alex, AK; Bariani, G; Braghirolli, MI; Hoff, PM; Moniz, CM; Nahas, C; Oliveira, SC; Riechelmann, R, 2016)
"To evaluate toxicity, local control, and survival of anal cancer patients treated with helical tomotherapy (HT) and concurrent 5-fluorouracil and mitomycin-C (5FU/MMC)."5.20Prospective phase II study of tomotherapy based chemoradiation treatment for locally advanced anal cancer. ( Doll, C; Field, C; Ghosh, S; Joseph, K; Mulder, K; Nijjar, T; Nijjar, Y; Schiller, D; Severin, D; Syme, A; Tankel, K; Usmani, N; Warkentin, H; Wong, C, 2015)
"Newer radiation techniques, and the application of continuous 5-FU exposure during radiation therapy using oral capecitabine may improve the treatment of anal cancer."5.17Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study. ( Beijnen, JH; Boot, H; Cats, A; Deenen, MJ; Dewit, L; Schellens, JH, 2013)
"The results of our trial--the largest in anal cancer to date--show that fluorouracil and mitomycin with 50."5.17Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial. ( Begum, R; Cunningham, D; Essapen, S; Falk, S; Glynne-Jones, R; Gollins, S; James, RD; Kadalayil, L; Ledermann, J; Leslie, M; Maughan, T; McDonald, A; Meadows, HM; Myint, AS; Saunders, MP; Sebag-Montefiore, D; Wilson, C, 2013)
"The long-term update of US GI Intergroup RTOG 98-11 anal cancer trial found that concurrent chemoradiation (CCRT) with fluorouracil (5-FU) plus mitomycin had a significant impact on disease-free survival (DFS) and overall survival (OS) compared with induction plus concurrent 5-FU plus cisplatin."5.17Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial. ( Ajani, JA; Benson, AB; Gunderson, LL; Haddock, MG; Mayer, RJ; Moughan, J; Pedersen, JE; Rich, TA; Thomas, CR; Willett, CG; Winter, KA, 2013)
"A multi-institutional phase 2 trial assessed the utility of dose-painted intensity modulated radiation therapy (DP-IMRT) in reducing grade 2+ combined acute gastrointestinal and genitourinary adverse events (AEs) of 5-fluorouracil (5FU) and mitomycin-C (MMC) chemoradiation for anal cancer by at least 15% compared with the conventional radiation/5FU/MMC arm from RTOG 9811."5.17RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. ( Esthappan, J; Goodyear, MD; Haddock, MG; Kachnic, LA; Myerson, RJ; Parikh, PJ; Rotman, M; Safran, H; Willett, CG; Willins, J; Winter, K, 2013)
"The United Kingdom Coordinating Committee on Cancer Research anal cancer trial demonstrated the benefit of combined modality treatment (CMT) using radiotherapy (RT), infusional 5-fluorouracil, and mitomycin C over RT alone."5.15"Mind the gap"--the impact of variations in the duration of the treatment gap and overall treatment time in the first UK Anal Cancer Trial (ACT I). ( Adams, R; Glynne-Jones, R; Gollins, S; James, R; Jitlal, M; McDonald, A; Meadows, HM; Northover, JM; Sebag-Montefiore, D, 2011)
"Although chemoradiation using 5-fluorouracil (5-FU) and mitomycin-C (MMC) is the standard of care in the treatment of anal cancer, many patients are unable to tolerate MMC."5.15Long-term follow-up of a Phase II trial of high-dose radiation with concurrent 5-fluorouracil and cisplatin in patients with anal cancer (ECOG E4292). ( Benson, AB; Catalano, PJ; Chakravarthy, AB; Mansour, EG; Martenson, JA; Mondschein, JK; Talamonti, MS; Wagner, H, 2011)
"Radiation Therapy Oncology Group (RTOG) 92-08 began as a single arm, Phase II trial for patients with anal cancer consisting of radiation (RT) + 5-flourouracil + mitomycin-C with a mandatory 2-week break and was amended after completion to evaluate the same treatment regimen without a treatment break."5.13Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08. ( Garcia, M; John, M; Konski, A; Krieg, R; Myerson, R; Pinover, W; Willett, C, 2008)
"Patients with previously untreated anal canal cancers with T3 or T4 tumors and/or extensive nodal involvement (bulky N2 or N3) received two 28-day cycles of induction treatment with infusional FU plus cisplatin followed by two 28-day cycles of FU plus mitomycin C with concurrent split-course radiation."5.13Induction therapy for poor-prognosis anal canal carcinoma: a phase II study of the cancer and Leukemia Group B (CALGB 9281). ( Budinger, S; Colacchio, TA; Day, JM; Ellerton, J; Goldberg, RM; Hopkins, J; Mayer, RJ; Meropol, NJ; Niedzwiecki, D; Shank, B; Tepper, J; Valone, F, 2008)
"A prospective clinical trial was performed to assess the response and toxicity associated with the use of high dose radiation therapy, 5-fluorouracil, and cisplatin in patients with anal cancer."5.08Initial results of a phase II trial of high dose radiation therapy, 5-fluorouracil, and cisplatin for patients with anal cancer (E4292): an Eastern Cooperative Oncology Group study. ( Benson, AB; Kaplan, EH; Lipsitz, SR; Mansour, EG; Martenson, JA; Otteman, LA; Schuchter, LM; Talamonti, MS; Wagner, H, 1996)
"Our trial shows that the standard treatment for most patients with epidermoid anal cancer should be a combination of radiotherapy and infused 5-fluorouracil and mitomycin, with surgery reserved for those who fall on this regimen."5.08Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research. ( , 1996)
"Concomitant external-beam radiochemotherapy (5-fluorouracil-mitomycin C) has become the standard of care in anal cancer since the '90s."5.01Pooled Analysis of external-beam RADiotherapy parameters in phase II and phase III trials in radiochemotherapy in Anal Cancer (PARADAC). ( Ajani, JA; Bosset, JF; Chakravarthy, AB; Christiaens, M; Collette, L; Glynne-Jones, R; Hannoun-Levi, JM; Haustermans, K; Konski, AA; Maingon, P; Matzinger, O; Meadows, H; Northover, J; Peiffert, D; Puyraveau, M; Rivin Del Campo, E; Winter, KA, 2019)
"Since the initial development of 5-fluorouracil and mitomycin as a standard of care platform for definitive anal cancer chemoradiotherapy, multiple studies have evaluated the optimal chemotherapy regimen, and radiotherapy technique."5.01Anal Cancer in the Era of Dose Painted Intensity Modulated Radiation Therapy: Implications for Regional Nodal Therapy. ( A Goodman, K; Ladbury, C; Olsen, JR; Schefter, TE, 2019)
"Standard treatment for locally advanced anal cancer is chemoradiotherapy with mitomycin C and fluorouracil."4.95Capecitabine in locally advanced anal cancer, do we need randomised evidence? ( Chong, LC; Healey, T; Michele, T; Price, TJ, 2017)
"Standard treatment for anal canal cancer is definitive radiochemotherapy (RCT) with 5-fluorouracil plus mitomycin C."4.86[Radiochemotherapy for locally advanced anal cancer]. ( Rödel, C, 2010)
"The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin."4.85Intensity-modulated radiation therapy for anal cancer. ( Czito, BG; Meyer, JJ; Pepek, JM; Willett, CG; Yoo, S, 2009)
"Consecutive patients with locally advanced (T2 ≥ 4 cm-T4 or N+) anal cancer scheduled for two cycles of concomitant 5-fluorouracil and mitomycin C chemotherapy were selected from an institutional database (n = 106)."4.02Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer. ( Johnsson, A; Nilsson, MP; Scherman, J, 2021)
"Between 2000 and 2015, a total of 112 consecutive patients with UICC stage I-IV anal cancer received chemoradiotherapy with 5‑fluororuracil and mitomycin C (CRT)."3.91Chemoradiotherapy with and without deep regional hyperthermia for squamous cell carcinoma of the anus. ( Fietkau, R; Grützmann, R; Matzel, KE; Ott, OJ; Raptis, D; Schmidt, M; Schneider, I; Semrau, S; Strnad, V; Uter, W, 2019)
"Definitive chemoradiation with concurrent 5-fluorouracil (5-FU)/mitomycin C (MMC) is an effective treatment for localized anal cancer, but it is associated with significant acute long-term treatment-related toxicity."3.91Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study. ( Adams, J; Allen, JN; Baglini, C; Ben-Josef, E; Blaszkowsky, LS; Clark, JW; DeLaney, TF; Drapek, LC; Hong, TS; Jiang, W; Metz, JM; Murphy, JE; Parikh, AR; Plastaras, JP; Ryan, DP; Wo, JY; Yeap, BY, 2019)
"During a regular MR control, the patient developed anaphylactic reaction to Gadolinium, and after that a rectosigmoid ischemia with total necrosis of the posterior rectal wall was diagnosed and surgically treated with Hartmann procedure."3.91Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication. ( Calvisi, G; Carlei, F; Di Sibio, A; Di Staso, M; Giuliani, A; Lombardi, L; Marchese, M; Romano, L; Romanzi, F; Schietroma, M, 2019)
" We investigated the prognostic role of baseline hemoglobin (Hb) in a cohort of anal cancer patients submitted to CT-RT with 5-fluorouracil and mitomycin C."3.88The prognostic role of hemoglobin levels in patients undergoing concurrent chemo-radiation for anal cancer. ( Andrikou, K; Arcadipane, F; Casadei Gardini, A; Casadei, C; Cascinu, S; Cassoni, P; Fornaro, L; Franco, P; Iorio, GC; Martini, S; Mistrangelo, M; Montagnani, F; Ricardi, U; Scartozzi, M, 2018)
"To obtain safety and preliminary efficacy data of the combination of ADXS11-001, live attenuated Listeria monocytogenes bacterium, with mitomycin, 5-fluorouracil (5-FU), and intensity modulated radiation therapy in locally advanced anal cancer."3.88Tolerability of ADXS11-001 Lm-LLO Listeria-Based Immunotherapy With Mitomycin, Fluorouracil, and Radiation for Anal Cancer. ( Barth, P; DiPetrillo, TA; Klipfel, A; Leonard, KL; Mantripragada, K; Oldenburg, N; Perez, K; Rajdev, L; Rosati, K; Roth, L; Safran, H; Schechter, S; Shah, N; Sheng, IY; Vrees, M, 2018)
"NRG Oncology RTOG 0529 assessed the feasibility of dose-painted intensity modulated radiation therapy (DP-IMRT) to reduce the acute morbidity of chemoradiation with 5-fluorouracil (5FU) and mitomycin-C (MMC) for T2-4N0-3M0 anal cancer."3.85Predictors of Radiation Therapy-Related Gastrointestinal Toxicity From Anal Cancer Dose-Painted Intensity Modulated Radiation Therapy: Secondary Analysis of NRG Oncology RTOG 0529. ( Abitbol, A; Chang, A; Chen, Y; Crane, CH; Doncals, DE; Fisher, B; Johnson, D; Kachnic, L; Michalski, J; Moughan, J; Myerson, R; Narayan, S; Olsen, JR; Schefter, TE, 2017)
"Fifty-six anal cancer patients from 2 institutions received definitive radiation therapy (median primary dose of 54 Gy) using intensity modulated radiation therapy (IMRT, n=49) or 3-dimensional (3D) conformal therapy (n=7) with concurrent 5-fluorouracil (5-FU) and mitomycin C."3.85Hematologic Nadirs During Chemoradiation for Anal Cancer: Temporal Characterization and Dosimetric Predictors. ( Aggarwal, S; Bazan, JG; Chang, DT; Golden, DW; Kopec, M; Lee, AY; Liauw, SL; Pelizzari, CA, 2017)
"The cohort included 45 patients with nonmetastatic anal cancer who underwent FDG-PET imaging prior to definitive chemoradiation with mitomycin-C and 5-fluorouracil."3.83Irradiation of FDG-PET-Defined Active Bone Marrow Subregions and Acute Hematologic Toxicity in Anal Cancer Patients Undergoing Chemoradiation. ( Allen, JN; Blaszkowsky, LS; Drapek, LC; Hong, TS; Jee, KW; Lee, LK; Murphy, JE; Niemierko, A; Rose, BS; Wang, Y; Wo, JY, 2016)
"Fulminant myocarditis is a rare but potentially life-threatening illness caused by 5-fluorouracil cardiotoxicity."3.83Rapid Extracorporeal Membrane Oxygenation Overcomes Fulminant Myocarditis Induced by 5‑Fluorouracil. ( Amraotkar, AR; DeFilippis, AP; Grubb, KJ; Pachika, A, 2016)
"Concomitant chemoradiotherapy of 5-fluorouracil and cisplatin with radiotherapy is a highly effective and well-tolerated treatment of anal cancer."3.81Concomitant chemoradiotherapy with Cisplatin plus 5-Fluorouracil for anal squamous cell carcinoma. ( El-Hadaad, HA; Roshdy, S; Wahba, HA, 2015)
"Concurrent chemoradiotherapy with 5-fluorouracil (5-FU) and mitomycin-C (MMC) is standard treatment for anal cancer."3.81Chemoradiotherapy for squamous cell carcinoma of the anal canal: Comparison of one versus two cycles mitomycin-C. ( Aleshin, A; Goldman, K; Lien, WW; Rao, AR; White, EC, 2015)
"Between 1976 and 2008, 116 patients with T2 node-negative anal cancer were treated curatively with RT alone (n=48) or by combined chemoradiation therapy (CRT) (n=68) incorporating mitomycin C and 5-fluorouracil."3.79Elective inguinal node irradiation in early-stage T2N0 anal cancer: prognostic impact on locoregional control. ( Allal, AS; Betz, M; Bieri, S; Ris, F; Roche, B; Roth, AD; Zilli, T, 2013)
"To investigate the prognostic value of epidermal growth factor receptor (EGFR) expression in pretreatment tumor biopsy specimens of patients with anal cancer treated with concurrent 5-fluorouracil and mitomycin C-based chemoradiation therapy (CRT)."3.79Epidermal growth factor receptor expression as prognostic marker in patients with anal carcinoma treated with concurrent chemoradiation therapy. ( Diallo-Georgiopoulou, M; Distel, L; Falk, S; Fraunholz, I; Kohler, D; Rödel, C; Rödel, F, 2013)
"Between 1976 and 2008, 146 patients with T1 (n=29) or T2 (n=117) N0 M0 anal cancer were treated curatively by RT alone (n=71) or by combined chemoradiotherapy (CRT) (n=75) consisting of mitomycin C±5-fluorouracil."3.78Node-negative T1-T2 anal cancer: radiotherapy alone or concomitant chemoradiotherapy? ( Allal, AS; Gervaz, P; Ozsahin, M; Roth, AD; Schick, U; Zilli, T, 2012)
"To investigate the prognostic value of survivin expression in pretreatment specimens from patients with anal cancer treated with concurrent 5-FU and mitomycin C-based chemoradiation (CRT)."3.78High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy. ( Distel, L; Falk, S; Fraunholz, I; Kohler, D; Rave-Fränk, M; Rödel, C; Rödel, F, 2012)
"Five patients with primary colorectal adenocarcinoma or anal squamous cell carcinoma were started on a 2-weeks-on, 1-week-off capecitabine dosing regimen in addition to other chemotherapeutic agents and/or radiation."3.78Capecitabine-induced chest pain relieved by diltiazem. ( Ambrosy, AP; Fisher, GA; Kunz, PL; Witteles, RM, 2012)
"For a woman with poorly-differentiated anal canal adenocarcinoma in acknowledgment of metastasis to right inguinal lymph node, we gave radiotherapy combined with capecitabine as chemotherapy."3.77[Preoperative chemoradiation (XELOX/RT) therapy for anal canal adenocarcinoma with the metastasis to inguinal lymph node]. ( Ide, Y; Makino, S; Murata, K, 2011)
"The current standard of care for the treatment of anal cancer as demonstrated by all of the completed phase 3 clinical trials remains 5-FU and mitomycin C in combination with radiation therapy."3.72Recent clinical trials summary. ( Bleday, R; Nathanson, DR; Thomas, CR, 2004)
"Myocardial ischemia induced by 5-fluorouracil (5-FU) is a relatively rare, but potentially serious, occurrence."3.70Failure of oral nitrate and calcium channel blocker therapy to prevent 5-fluorouracil-related myocardial ischemia: a case report. ( Akpek, G; Hartshorn, KL, 1999)
"Between 1982 and 1992, 139 patients with epidermoid carcinoma of the anal canal were treated by radiation and chemotherapy with 5-fluorouracil (5-Fu) and mitomycin C (MMC)."3.69[The prognostic factors following the simultaneous radiochemotherapy of anal canal carcinoma in a multicenter series of 139 patients]. ( Budach, V; Döker, R; Grabenbauer, GG; Huber, K; Hültenschmidt, B; Hutter, M; Kuhne-Velte, HJ; Panzer, M; Rühl, U; Wendt, T, 1994)
"Forty-two consecutive patients with anal canal cancer were treated with 15 fractions of 30-Gy photon beam radiation therapy administered anteroposterior-posteroanterior in conjunction with chemotherapy with 5-fluorouracil and mitomycin C."3.69Cancer of the anal canal: treatment with chemotherapy and low-dose radiation therapy. ( Anderson, PJ; Frost, DB; Kagan, AR; Latino, F; Peddada, AV; Rao, AR; Shah, KH; Smith, DE, 1994)
"Acute myocardial infarction was observed in two patients receiving standard intravenous doses of 5-fluorouracil (5-FU)-based chemotherapy."3.68Thrombogenicity of intravenous 5-fluorouracil alone or in combination with cisplatin. ( Esparaz, B; Green, D; Kies, M; Kuzel, T, 1990)
"Twenty-four patients with carcinoma of the anus were treated with a combined regimen of external irradiation (50 Gy) and mitomycin C and 5-fluorouracil."3.67Primary treatment of carcinoma of the anus by combined radiotherapy and chemotherapy. ( Flokkmann, A; Fosså, SD; Guldvog, I; Haffner, J; Karlsen, KO; Tveit, KM, 1989)
"Neoadjuvant therapy combining 5-fluorouracil, mitomycin C, and moderate-dose radiotherapy was given preoperatively to 29 patients with adenocarcinoma of the rectum, 3 patients with squamous cell cancer, and 1 patient with basaloid carcinoma of the anus."3.67Combined preoperative neoadjuvant radiotherapy and chemotherapy for anal and rectal cancer. ( Muff, NS; Shetabi, H; Smith, DE, 1986)
"Anal squamous cell carcinoma (ASCC) is a rare tumor; it accounts for about 2% of gastrointestinal tumors."3.11Capecitabine in the treatment of anal squamous cell carcinoma. ( Radka, L; Zdeňka, P, 2022)
"Anal squamous cell carcinoma (ASqCC) is a rare malignancy, traditionally treated with combined chemoradiation, with a continuous infusion of 5-fluorouracil (5-FU) and mitomycin C (MMC)."3.01Comparison of intravenous 5-Fluorouracil with Oral Capecitabine in the Treatment of Anal Squamous Cell Carcinoma Using Modern Radiation Techniques. ( Ben David, MA; Grinberg, V; Hod, K; Kalmus, Y; Levin, D; Lipski, Y; Pfeffer, RM; Schlosser, S; Zalmanov, S, 2023)
"Purpose Squamous cell carcinoma of the anal canal (SCCAC) is characterized by high locoregional failure (LRF) rates after definitive chemoradiation (CRT), associated with anogenital human papilloma virus, and often appears in HIV infection."2.84Cetuximab Plus Chemoradiotherapy for HIV-Associated Anal Carcinoma: A Phase II AIDS Malignancy Consortium Trial. ( Aboulafia, D; Fitzgerald, TJ; Henry, DH; Kachnic, L; Lee, JY; Mitsuyasu, R; Palefsky, J; Rajdev, L; Ratner, L; Sparano, JA; Wachsman, W, 2017)
"Purpose Squamous cell carcinoma of the anal canal (SCCAC) is characterized by high locoregional failure (LRF) rates after sphincter-preserving definitive chemoradiation (CRT) and is typically associated with anogenital human papilloma virus infection."2.84Cetuximab Plus Chemoradiotherapy in Immunocompetent Patients With Anal Carcinoma: A Phase II Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group Trial (E3205). ( Armstrong, KI; Benson, AB; El-Rayes, BF; Fitzgerald, TJ; Garg, MK; Kalnicki, S; Mitchell, EP; Moriarty, DJ; Mulcahy, MF; Nabbout, NH; Onitilo, AA; Palefsky, J; Sparano, JA; Whittington, R; Zhao, F, 2017)
"Anal cancer is considered a rare tumor, accounting for 6 % of digestive cancers and about 2000 new cases per year in France."2.82[Anal cancer: Focus on current treatment and future perspective]. ( Combet-Curt, V; Delhiat, AC; Vendrely, V, 2022)
" Conclusions HT with daily IGRT is efficacious and safe in the treatment of anal canal cancer patients, and is considered in our department standard of care in this clinical setting."2.82Efficacy and safety of helical tomotherapy with daily image guidance in anal canal cancer patients. ( Bouchaab, H; Bourhis, J; De Bari, B; Hanhloser, D; Jumeau, R; Matzinger, O; Mirimanoff, RO; Ozsahin, EM; Troussier, I; Vallet, V; Wagner, AD, 2016)
"The treatment for squamous cell carcinoma of the anus changed dramatically during the study period."2.80The Effect of the UK Coordinating Centre for Cancer Research Anal Cancer Trial (ACT1) on Population-based Treatment and Survival for Squamous Cell Cancer of the Anus. ( Aravani, A; Downing, A; Finan, PJ; Lawton, S; Morris, EJ; Sebag-Montefiore, D; Thomas, JD, 2015)
"The MTDs were determined as 5FU 800 mg/m(2) on RT days 1-4 and 29-32 and MMC 8 mg/m(2) on days 1 and 29 when combined with IMRT/VMAT with SIB and cetuximab in locally advanced anal cancer."2.80Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer. ( Gunnlaugsson, A; Guren, MG; Johnsson, A; Leon, O; Radu, C, 2015)
"Chemoradiotherapy (CRT) for squamous cell carcinoma of the anus (SCCA) may cause significant toxicity, and concerns exist about its tolerability in the elderly."2.79Impact of advancing age on treatment and outcomes in anal cancer. ( Chander, S; Chu, J; Foo, M; Heriot, A; Lee, MT; Leong, T; Link, E; Michael, M; Ngan, SY; Tomaszewski, JM; Tran, PK, 2014)
"Anal cancer is an increasing issue in HIV-positive men who have sex with men (MSM)."2.78Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial. ( de Vries, HJ; Dijkgraaf, MG; Prins, JM; Richel, O; van Noesel, CJ, 2013)
"Fifty-eight anal cancer patients were treated with concurrent chemotherapy and IMRT."2.78Dosimetric parameters predictive of acute gastrointestinal toxicity in patients with anal carcinoma treated with concurrent chemotherapy and intensity-modulated radiation therapy. ( Beriwal, S; DeFoe, SG; Heron, DE; Kabolizadeh, P, 2013)
"The trial was prematurely stopped after the declaration of 15 serious adverse events (SAEs) in 14 out of 16 patients."2.78Unexpected toxicity of cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: results of the UNICANCER ACCORD 16 phase II trial. ( Azria, D; Becouarn, Y; Conroy, T; Delarochefordiere, A; Deutsch, E; Ezra, P; Juzyna, B; Lemanski, C; Levy, A; Malekzadeh, K; Malka, D; Martel-Lafay, I; Miglianico, L; Paris, E; Pignon, JP; Rio, E, 2013)
" Maintenance chemotherapy started 4-8 weeks later, three courses repeated every 21 days, using 5-FU/CDDP doses above, with MMC reduced to 7 mg/m(2) and administered with the first and third cycles."2.77Three cytotoxic drugs combined with pelvic radiation and as maintenance chemotherapy for patients with squamous cell carcinoma of the anus (SCCA): long-term follow-up of a phase II pilot study using 5-fluorouracil, mitomycin C and cisplatin. ( Cunningham, D; Davidson, N; Glynne-Jones, R; Grieve, R; Hurman, DC; Levine, E; Meadows, HM; Plowman, PN; Sebag-Montefiore, D, 2012)
"The first UKCCCR Anal Cancer Trial (1996) demonstrated the benefit of chemoradiation over radiotherapy (RT) alone for treating epidermoid anal cancer, and it became the standard treatment."2.75Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I). ( Glynne-Jones, R; James, R; Jitlal, M; Ledermann, J; Meadows, H; Northover, J; Sebag-Montefiore, D; Wan, S, 2010)
"To assess the feasibility and activity of radio-chemotherapy with mitomycin C (MMC) and cisplatin (CDDP) in locally advanced squamous cell anal carcinoma with reference to radiotherapy (RT) combined with MMC and fluorouracil (5-FU)."2.74Mitomycin C with continuous fluorouracil or with cisplatin in combination with radiotherapy for locally advanced anal cancer (European Organisation for Research and Treatment of Cancer phase II study 22011-40014). ( Bosset, JF; Collette, L; Haustermans, K; Koswig, S; Maingon, P; Matzinger, O; Mineur, L; Mueller, RP; Radosevic-Jelic, L; Roelofsen, F; Van Der Steen-Banasik, EM; Van Houtte, P, 2009)
"These tumours are assessed as rectal cancer using immunohistochemical and radiological tests, and certain criteria (localisation, relationship with neighbouring structures) have to be fulfilled to make the diagnosis."2.72Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations. ( Astaras, C; Bornand, A; Koessler, T, 2021)
"Patients were randomly assigned to undergo chemotherapy with 5-fluorouracil (5-FU) and mitomycin-C combined with radiotherapy with (arm A: 24 patients) or without ICHT (arm B: 25 patients)."2.71Chemoradiotherapy combined with intracavitary hyperthermia for anal cancer: feasibility and long-term results from a phase II randomized trial. ( Dardoufas, C; Gennatas, C; Kouloulias, V; Kouvaris, J; Papavasiliou, C; Plataniotis, G; Uzunoglu, N; Vlahos, L, 2005)
"An alternative approach to anal Bowen's disease was investigated."2.71Topical 5-fluorouracil in the management of extensive anal Bowen's disease: a preferred approach. ( Arnold, LK; Foote, JE; Graham, BD; Jetmore, AB, 2005)
"In all, 16 patients with biopsy-proven squamous cell carcinoma of the anal canal or margin and performance status or co-morbidity precluding the use of full-dose CRT were included in this protocol."2.71Effective treatment of anal cancer in the elderly with low-dose chemoradiotherapy. ( Charnley, N; Chesser, P; Choudhury, A; Cooper, RA; Sebag-Montefiore, D, 2005)
"Patients with residual tumor on posttreatment biopsy were treated with a salvage regimen that consisted of additional pelvic RT (9 Gy), 5-FU, and cisplatin (100 mg/m2)."2.68Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study. ( Coia, L; Doggett, S; Flam, M; John, M; Kerman, H; Murray, K; Myerson, R; Pajak, TF; Petrelli, N; Quivey, J; Rotman, M, 1996)
"The patients had T3-4NO-3 or T1-2N1-3 anal cancer."2.68Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro ( Bartelink, H; Bosset, JF; Eschwege, F; Gonzalez, DG; Peiffert, D; Pierart, M; Roelofsen, F; Rougier, P; van Glabbeke, M, 1997)
"Mitomycin's role in anal cancer is being evaluated in a randomized clinical trial by the Radiation Therapy Oncology Group."2.67Mitomycin in anal canal carcinoma. ( Catton, CN; Cummings, BJ; Keane, TJ; O'Sullivan, B; Wong, CS, 1993)
"Dinitrochlorobenzene was used to eradicate lesions that had been resistant to treatment with podophyllum resin."2.64Condyloma. A new epidemic. ( Meiselbaugh, DM; Moore, GE; Norton, LW, 1978)
" Management of these adverse effects is reviewed, as are future directions in anal cancer treatment and their impact on toxicity."2.55Evolution and Management of Treatment-Related Toxicity in Anal Cancer. ( Czito, BG; Kachnic, LA; Ludmir, EB, 2017)
" The areas of debate and development include the dosing and timing of MMC delivery, the role of cisplatin chemotherapy as an alternative to MMC, the replacement of the standard 96-h infusion of 5FU with oral capecitabine, the use of targeted chemotherapy agents, and the duration and dose of RT."2.53Advances in the Management of Anal Cancer. ( Goodman, KA; Julie, DR, 2016)
"The majority of anal cancers are squamous cell carcinomas, and they are treated according to stage."2.52Anal cancer treatment: current status and future perspectives. ( Abdayem, P; Antoun, J; Ghosn, M; Kourie, HR; Nasr, D, 2015)
"Although anal canal squamous cell carcinoma is rare, the general practitioner should consider this diagnosis in a patient with persistent lower abdominal symptoms."2.47[Management of anal canal carcinoma]. ( Betz, M; Cochet, S; George, AC; Roth, A; Thang, NN, 2011)
"We report a case with perianal squamous cell carcinoma, which showed a complete response more than five years after chemoradiotherapy."2.47[A case of perianal squamous cell carcinoma attaining a complete response over five years with chemoradiotherapy]. ( Imada, S; Ishikawa, O; Kishi, K; Miyashiro, I; Motoori, M; Nishiyama, K; Noura, S; Ohue, M; Shingai, T; Yano, M, 2011)
"The role of cisplatin in anal cancer is not completely clear, although an ongoing randomized trial (Anal Cancer Trial II) may help clarify the role of cisplatin."2.44Current treatment for localized anal carcinoma. ( Ajani, JA; Crane, CH; Das, P, 2007)
"Case 2: A 74-year-old female with anal squamous cell carcinoma Stage II was treated by chemoradiotherapy with tegafur/uracil, external irradiation (30 Gy) and interstitial irradiation (24 Gy)."2.42[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma]. ( Fujitani, K; Hirao, M; Ikenaga, M; Kashiwazaki, M; Masuda, N; Mishima, H; Sawamura, T; Takeda, Y; Takeno, A; Tsujinaka, T, 2004)
"During the past two decades, anal cancer has served as a paradigm for the successful application of chemoradiation to solid tumours; so far, it remains one of the few carcinomas of the gastrointestinal tract which are curable without the need for definitive surgery."2.42Chemotherapeutic options in the management of anal cancer. ( Allal, AS; Gervaz, P; Morel, P; Roth, A, 2004)
"Mitomycin C and 5 FU were delivered on weeks 1 and 5 of the irradiation."2.41[Radiochemotherapy in anal canal epidermoid cancer]. ( Peiffert, D, 2000)
"The majority of these cases were anal cancers with proximal extension into the rectum and were excluded."2.40Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature. ( Francis, B; Juturi, JV; Koontz, PW; Wilkes, JD, 1999)
"Five-year survival rates were 57% for squamous cell carcinoma, 63% for adenocarcinoma, and 33% for melanoma."2.40Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes. ( Klas, JV; Madoff, RD; Rothenberger, DA; Wong, WD, 1999)
" In this study, we report the safety and efficacy of cetuximab (an epidermal growth factor receptor inhibitor) in combination with 5-FU plus irinotecan based chemotherapy."1.91Efficacy and tolerance of cetuximab in combination with 5 FU plus irinotecan based chemotherapy in metastatic squamous cell anal carcinoma. ( Boige, V; Boilève, A; Cervantes, B; Ducreux, M; Hollebecque, A; Malka, D; Smolenschi, C; Valery, M, 2023)
"Anal cancer is a rare form of gastrointestinal malignancy, and treatment is often confined to specialist centres."1.91Concurrent Chemo-radiotherapy in Anal Squamous Cell Carcinoma: A Retrospective Review of a Tertiary Centre Experience. ( Elmasry, A; Giridharan, S; Patel, C, 2023)
"International guidelines regarding the treatment of squamous cell carcinoma of the anus (SCCA) recommend intensity-modulated radiotherapy (IMRT) combined with mitomycin-based chemotherapy (CT)."1.91Treatment, outcome, and prognostic factors in non-metastatic anal cancer: The French nationwide cohort study FFCD-ANABASE. ( Baba-Hamed, N; Crehange, G; Diaz, O; Drouet, F; Hautefeuille, V; Hummelsberger, M; Larrouy, A; LE Malicot, K; Lemanski, C; Lepage, C; Lievre, A; Menager-Tabourel, E; Minsat, M; Mornex, F; Peiffert, D; Pommier, P; Quero, L; Regnault, P; Rivin Del Campo, E; Ronchin, P; Saint, A; Tougeron, D; Vendrely, V; Zasadny, X, 2023)
" Gastrointestinal toxicity was retrospectively graded according to Common Terminology Criteria for Adverse Events (CTCAE) version 5."1.72Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer. ( Gunnlaugsson, A; Johnsson, A; Nilsson, MP; Scherman, J, 2022)
"Although rare, the rate of squamous cell carcinoma of the anus (SCCA) is rising globally."1.72Current treatment and future directions in the management of anal cancer. ( Eng, C; Hong, TS; Kachnic, LA; Ludmir, EB; Messick, CA; Tchelebi, LT; Zaorsky, NG, 2022)
"Our results suggest IMRT-based CRT with concurrent fluoropyrimidine and cisplatin is a safe and feasible option for patient with SCCA and may cause less acute toxicity."1.72Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution. ( Bednarski, BK; Chang, GJ; Das, P; Delclos, ME; Eng, C; Holliday, EB; Jennings, K; Johnson, B; Koay, EJ; Koong, AC; Ludmir, EB; Messick, CA; Minsky, BD; Morris, VK; Rodriguez-Bigas, MA; Skibber, JM; Smith, GL; Taniguchi, C; Tillman, MM; You, YN, 2022)
"Novel toxicity metrics that account for all adverse event (AE) grades and the frequency of may enhance toxicity reporting in clinical trials."1.72Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529. ( Ajani, J; Augspurger, ME; Crane, CH; Doncals, DE; Garg, MK; Kachnic, LA; Kharofa, JR; Kim, H; Lee, RJ; Mamon, HJ; Meyer, JE; Moughan, J; Narayan, S; Okawara, GS; Schefter, TE; Schwartz, MA; Swanson, TA; Yothers, G; Zaki, BI, 2022)
"Twenty-five patients with squamous cell carcinoma of the anal canal were treated at our centre from 2012 to 2019 using IMRT based chemoradiation."1.72Outcomes of Squamous Cell Carcinoma Anal Canal treated with IMRT-VMAT-based Concurrent Chemoradiation: a Single Institutional Experience. ( Ram, TS; Ramireddy, JK; Sathyamurthy, A; Singh, K, 2022)
"Anal cancer is a rare disease that has doubled in incidence over the last four decades."1.62Molecular and genomic characterisation of a panel of human anal cancer cell lines. ( Behrenbruch, CC; Bernardi, MP; Chittleborough, TJ; Di Costanzo, N; Guerra, GR; Hawkes, D; Haynes, NM; Heriot, AG; Kong, JC; Liu, DS; Lupat, R; Millen, RM; Mitchell, C; Ngan, SY; Phillips, WA; Ramsay, RG; Read, M; Roth, S; Sampurno, S; Sia, J; Teh, J; Tothill, RW; Xu, H; Yu, J, 2021)
"Anal squamous cell carcinoma has rarely been reported in the setting of ulcerative colitis."1.62Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols? ( Click, B; Hull, TL; Lightner, AL; McMichael, J; Regueiro, M; Steele, SR; Vaidya, P, 2021)
"Definitive chemoradiation for anal cancer is effective but may be associated with toxic effects, and some patients may not be able to complete the planned treatment."1.56Factors Associated With Chemoradiation Therapy Interruption and Noncompletion Among Patients With Squamous Cell Anal Carcinoma. ( Booth, CM; Brogly, SB; Hanna, TP; Kalyvas, M; Ko, G; Li, W; Patel, SV; Raphael, MJ, 2020)
"Among patients with anal cancer, chemoradiotherapy is often associated with toxicities that diminish quality of life."1.56Patient-Reported GI Outcomes in Patients With Anal Cancer Receiving Modern Chemoradiation. ( Abi Jaoude, J; Colbert, LE; Das, P; El Alam, MB; Holliday, EB; Klopp, AH; Koay, EJ; Kouzy, R; Lin, D; Minsky, BD; Taniguchi, CM, 2020)
"Acute hematotoxicity (G3, 4, 5 according to Common Terminology Criteria for Adverse Events - CTCAE) was significantly associated with the concomitant chemoradiotherapy (P = 0."1.56Haematotoxicity in IMRT/VMAT curatively treated anal cancer. ( Drbohlavová, T; Jirkovská, M; Lohynská, R; Malinová, B; Mazaná, E; Nýdlová, A; Stankušová, H; Veselský, T, 2020)
"Metastatic squamous cell carcinomas (SCC) of the anal canal are rare and there is no international consensus on their second-line management."1.51Mitomycin and 5-fluorouracil for second-line treatment of metastatic squamous cell carcinomas of the anal canal. ( Benezery, K; Cavaglione, G; Evesque, L; Falk, AT; Francois, E; Montagne, L; Saint, A, 2019)
"For 70 women with anal cancer treated at our department, acute and chronic side effects and quality of life (QoL) were evaluated with questionnaires using the Common Terminology Criteria for Adverse Events (CTCAE v."1.51Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects. ( Adeberg, S; Debus, J; Haefner, MF; Herfarth, K; Koerber, SA; Krug, D; Liermann, J; Seither, B; Slynko, A; Sterzing, F, 2019)
"CRT for anal cancer is becoming a standard therapy but local recurrence is possible."1.51[A Case of Colostomy-Free and Long-Term Survival with 5-FU/CDDP for Local Recurrence of Anal Cancer after Chemoradiation Therapy]. ( Aoyama, Y; Hikosaka, Y; Karamatsu, S; Katada, T; Kato, A; Mita, K; Nishida, T; Nishido, T; Saito, M; Sakamoto, S; Shibata, T; Teranishi, F; Tsuchiya, T, 2019)
" Patient acute gastrointestinal toxicity was recorded using Common Terminology Criteria of Adverse Events (CTCAE) diarrhoea grading."1.48Intensity-modulated Radiotherapy for Anal Cancer: Dose-Volume Relationship of Acute Gastrointestinal Toxicity and Disease Outcomes. ( Amor, H; Blakey, D; Chao, M; Guerrieri, M; Guiney, M; Ho, H; Macleod, C; Melven, L; Ng, M; Skelton, J; Subramanian, B, 2018)
"A retrospective cohort of 190 anal cancer patients treated at 3 academic centers with concurrent chemo-RT employing either SIB or SeqB was analysed."1.48Comparing simultaneous integrated boost vs sequential boost in anal cancer patients: results of a retrospective observational study. ( Arcadipane, F; Casadei Gardini, A; Cassoni, P; Ceccarelli, M; Créhange, G; De Bari, B; Evangelista, A; Franco, P; Furfaro, G; Iorio, GC; Lepinoy, A; Martini, S; Mistrangelo, M; Passardi, A; Ricardi, U; Trino, E; Valgiusti, M, 2018)
"Anal canal cancer occasionally accompanies extramammary Paget disease."1.48Anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease, successfully treated with modified FOLFOX6: a case report. ( Hirose, S; Hyodo, I; Kawai, H; Moriwaki, T; Sato, M; Suganuma, D; Tajima, H; Uchida, Y; Watanabe, R; Yamada, T; Yamamoto, Y; Yamaura, M, 2018)
"Grade 3-4 neutropenia was seen in 10/23 patients (43%)."1.46PET-CT guided SIB-IMRT combined with concurrent 5-FU/MMC for the treatment of anal cancer. ( Beer, J; Bodis, S; Oehler, C; Vlachopoulou, V; von Moos, R; Zimmermann, M; Zwahlen, DR, 2017)
"Stage IV squamous cell carcinoma of the anus outcomes are poor, but first-line chemotherapy can enable good response rates."1.46Multimodal Therapy of Squamous Cell Carcinoma of the Anus With Distant Metastasis: A Single-Institution Experience. ( Benezery, K; Cavaglione, G; Doyen, J; Evesque, L; Follana, P; François, E; Reure, J; Tuan Falk, A, 2017)
"We report a case of perianal squamous cell carcinoma and left inguinal lymph node metastasis that showed a complete response more than 5 years after chemotherapy and concomitant proton beam therapy."1.46[A Case of Perianal Squamous Cell Carcinoma with Left Inguinal Lymph Node Metastasis That Showed a Complete Response More Than Five Years after Chemotherapy and Concomitant Proton Beam Therapy]. ( Abe, T; Azami, A; Honda, M; Nakamura, T; Sato, A; Suzuki, N; Tada, T; Takano, Y; Teranishi, Y; Todate, Y; Waragai, M, 2017)
"Locally advanced anal cancer patients, especially with T4 disease and fistula, have a dismal prognosis."1.46Early closure of fistula using neo-adjuvant intra-arterial chemotherapy in locally advanced anal cancer. ( Allal, AS; Cacheux, W; Dietrich, PY; Fernandez, E; Ho, L; Koessler, T; Puppa, G; Ris, F; Roche, B; Roth, A; Zilli, T, 2017)
"Treatment with uridine triacetate was arranged in the emergency department."1.46The successful treatment of 5-fluorouracil (5-FU) overdose in a patient with malignancy and HIV/AIDS with uridine triacetate. ( Geller, RJ; Morgan, BW; Santos, C, 2017)
"However, anal cancers are rare in patients with HIV in Japan."1.43[Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV]. ( Ishida, H; Mita, E; Mori, K; Nakazuru, S; Nishio, K; Sakakibara, Y; Sugimoto, A; Uehira, T; Yajima, K; Yamada, T, 2016)
"45 patients with anal cancer who underwent pre-treatment FDG-PET/CT were included."1.43Metabolic tumour volume of anal carcinoma on (18)FDG PET/CT before combined radiochemotherapy is the only independant determinant of recurrence free survival. ( Behrendt, FF; Eble, MJ; Heinzel, A; Mohammadkhani Shali, S; Mottaghy, FM; Schmitt, V; Verburg, FA; Winz, OH, 2016)
"Anal cancer was diagnosed in a 36-year-old nulliparous woman."1.43Successful Delivery in a 39-Year-Old Patient with Anal Cancer after Fertility-Preserving Surgery Followed by Primary Chemoradiation and Low Anti-Mullerian Hormone Level. ( Biel, P; Cordes, T; Köhler, C; Marnitz, S, 2016)
"Anal cancer is uncommon."1.42Review of anal cancer patients at the Ottawa hospital. ( Abunassar, M; Asmis, T; Jonker, DJ; Reinders, J, 2015)
"TomoTherapy for locally advanced anal cancer is feasible."1.42French multicentre clinical evaluation of helical TomoTherapy for anal cancer in a cohort of 64 consecutive patients. ( Belhomme, S; Benech, J; Doussau, A; Frison, E; Henriques de Figueiredo, B; Kantor, G; Lisbona, A; Mahé, MA; Maire, JP; Nomikossoff, N; Rio, E; Vendrely, V, 2015)
"Inguinal lymph node metastasis is predictive of locoregional recurrence and poor overall survival in anal carcinoma."1.40Inguinal lymph node recurrence in the untreated groin of patients with anal carcinoma. ( Blinde, SE; Mens, JW; Nuyttens, JJ; Olofsen, M; Schasfoort, R; Verhoef, C, 2014)
"Capecitabine is an established treatment alternative to intravenous 5-fluorouracil (5-FU) for patients with rectal cancer receiving chemoradiotherapy."1.40Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option. ( Beijnen, JH; Cats, A; Dewit, L; Meulendijks, D; Schellens, JH; Tomasoa, NB; van Tinteren, H, 2014)
"Metastatic squamous cell carcinoma (SCCA) of the anal canal is a rare malignancy for which no standard treatment algorithm exists."1.40The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal. ( Chang, GJ; Crane, CH; Das, P; Eng, C; Ohinata, A; Pathak, P; Phillips, JK; Rodriguez-Bigas, M; Rogers, JE; Sethi, S; Vauthey, JN; Wolff, RA; Xing, Y; You, YN, 2014)
"The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life."1.39Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy. ( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013)
"Chemoradiation for anal cancer yields effective tumor control, but is associated with significant acute toxicity."1.38Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy. ( Blaszkowsky, LS; Coen, JJ; Hartshorn, K; Hong, TS; Kachnic, LA; Kwak, EL; Ryan, DP; Tsai, HK; Willins, JD, 2012)
"Sixty patients with anal cancer were identified."1.38Chemoradiotherapy for anal cancer in HIV patients causes prolonged CD4 cell count suppression. ( Alfa-Wali, M; Allen-Mersh, T; Antoniou, A; Bower, M; Gazzard, B; Nelson, M; Newsom-Davis, T; Tait, D, 2012)
"CRT is a highly effective approach in anal cancer."1.38Twenty-five-year experience with radical chemoradiation for anal cancer. ( Chander, S; Chu, J; Foo, M; Heriot, A; Lee, MT; Leong, T; Link, E; Lynch, CA; Mackay, J; Michael, M; Ngan, SY; Tomaszewski, JM; Tran, P; Vazquez, M, 2012)
"Pre- and post-treatment staging of anal cancer are often inaccurate."1.38Role of positron emission tomography-computed tomography in the management of anal cancer. ( Baccega, M; Bellò, M; Cassoni, P; Cravero, F; Filippini, C; Fora, G; Lesca, A; Milanesi, E; Mistrangelo, M; Morino, M; Munoz, FH; Pelosi, E; Racca, P; Ricardi, U; Skanjeti, A, 2012)
"To update our experience in treating squamous cell carcinoma of the anal margin with definitive radiotherapy (RT)."1.37Squamous cell carcinoma of the anal margin: the university of Florida experience. ( Balamucki, CJ; George, TJ; Kirwan, JM; Mendenhall, WM; Morris, CG; Newlin, HE; Rout, WR; Zlotecki, RA, 2011)
"HIV-positive patients with anal cancer can be treated with standard CRT, with the same tolerability and toxicity as HIV-negative patients."1.37Concurrent chemoradiotherapy with 5-fluorouracil and mitomycin C for anal carcinoma: are there differences between HIV-positive and HIV-negative patients in the era of highly active antiretroviral therapy? ( Fraunholz, I; Gerstein, J; Haberl, A; Jäck, K; Rabeneck, D; Rödel, C; Weiss, C, 2011)
"A total of 88 patients treated for anal cancer at our institution between 1990 and 2006 were identified from our database."1.37Quality of life outcomes in patients with anal cancer after combined radiochemotherapy. ( Hägele, V; Mai, SK; Welzel, G; Wenz, F, 2011)
"Squamous cell cancer of the anal canal (anal cancer) is a rare disease but with worldwide increasing incidence."1.37Single-agent paclitaxel in advanced anal cancer after failure of cisplatin and 5-fluorouracil chemotherapy. ( Abbas, A; Fakih, M; Nehme, E, 2011)
"Eighty-four patients with invasive anal cancer treated with definitive external beam radiotherapy (RT) with a mandatory split of 12 days (52 patients, Montreal, Canada) or without an intended split (32 patients, Zurich, Switzerland) were reviewed."1.36Chemo-radiation with or without mandatory split in anal carcinoma: experiences of two institutions and review of the literature. ( Bahary, JP; Ciernik, IF; Donath, D; Lütolf, UM; Oehler, C; Provencher, S, 2010)
"From 1991 to 2005, 58 patients with anal cancer were curatively treated with CRT."1.36Quality of life and tumor control after short split-course chemoradiation for anal canal carcinoma. ( Donath, D; Fortin, B; Jolicoeur, M; Lavertu, S; Oehler, C; Provencher, S, 2010)
"HIV-positive patients with squamous cell carcinoma of the canal treated at Continuum Cancer Centers-affiliated hospitals were identified from tumor registries."1.36Efficacy and toxicity of chemoradiation in the treatment of HIV-associated anal cancer. ( Ennis, RD; Evans, A; Grossbard, M; Hauerstock, D, 2010)
"Blood test showed severe disseminated intravascular coagulation (DIC)."1.36[mFOLFOX6 for treatment of anal canal cancer with disseminated carcinomatosis of bone marrow--a case report]. ( Doi, M; Okamoto, Y; Shinozaki, K; Yamauchi, M, 2010)
"We report three cases of anal canal squamous cell carcinoma treated with radiotherapy combined with S-1 and mitomycin C(MMC)."1.36[Three cases of radiotherapy combined with S-1 and mitomycin C for anal canal squamous cell carcinomas]. ( Akaike, M; Motohashi, O; Nakayama, N; Nakayama, Y; Nishimura, K; Nonaka, T; Shiozawa, M; Takagi, S; Yoshii, T, 2010)
"We report a case of squamous cell carcinoma of the anus with associated HIV infection."1.36[A case of squamous cell carcinoma of the anal cancer with associated human immunodeficiency virus]. ( Fujitani, K; Hirao, M; Ikenaga, M; Mishima, H; Miyamoto, A; Miyazaki, M; Nakamori, S; Omiya, H; Sueda, K; Takami, K; Tsujie, M; Tsujinaka, T; Yasui, M; Yoshida, K, 2010)
"We analyzed 48 consecutive anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiation therapy."1.35Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy. ( Aydogan, B; Chmura, SJ; Devisetty, K; Jani, AB; Kindler, HL; Mell, LK; Miller, RC; Mundt, AJ; Roeske, JC; Salama, JK; Schomas, DA, 2008)
"Here, we report a case of a male with anal cancer who was treated with 5-FU 1000 mg/m(2), continuous infusion for 5 days q4 weeks."1.33Intermediate dose 5-fluorouracil-induced encephalopathy. ( Choi, HJ; Chung, HC; Jeung, HC; Kim, YA; Rha, SY; Seong, JS, 2006)
"Most patients with anal cancer can expect to retain a functional sphincter after chemoradiation/radiation."1.33The bottom line: outcomes after conservation treatment in anal cancer. ( Dwyer, MK; Gebski, VJ; Jayamohan, J, 2006)
"We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions."1.33[Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation]. ( Almendral, ML; Aranda, F; Echenique-Elizondo, M; Erro, JM; Ibáñez, J; Valenti, C, 2006)
"Anal cancer is the first tumour in which chemoradiotherapy with the intent of organ preservation has largely replaced surgery and is an interesting model of modern multimodal oncological treatment."1.33Chemoradiotherapy of anal cancer is feasible in elderly patients: treatment results of mitomycin-5-FU combined with radiotherapy at Helsinki University Central Hospital 1992-2003. ( Arponen, P; Blomqvist, C; Saarilahti, K; Tenhunen, M; Vaalavirta, L, 2006)
"Nine (18%) have died of anal cancer."1.32Concurrent chemoradiotherapy for squamous cell carcinoma of the anus using a shrinking field radiotherapy technique without a boost. ( Melcher, AA; Sebag-Montefiore, D, 2003)
"Treatment of T3 and T4 anal cancer with combined chemotherapy and EBRT, followed by interstitial implant results in an ultimate local-regional control of 84%, after the inclusion of selected APR."1.32Treatment of T3 and T4 anal carcinoma with combined chemoradiation and interstitial 192Ir implantation: a 10-year experience. ( Cosmatos, HA; Hsiang, JY; Hwang, JM; Kagan, RA; Kaptein, JS; Rao, AR; Tome, M; Wang, R, 2004)
"A complete remission of anal cancer was achieved in both patients with minimal acute and late toxicities."1.31Successful chemoradiotherapy for anal cancer despite previous radical radiotherapy for gynaecological malignancy. ( Arnott, SJ; Leslie, MD; Subramaniam, R, 2002)
"The median CD4 count at diagnosis of anal cancer was 209 cells/microl (range: 29-380 cells/microl), 5 had prior AIDS defining diagnoses."1.31Treatment of HIV-associated invasive anal cancer with combined chemoradiation. ( Bower, M; Cleator, S; Fife, K; Gazzard, B; Nelson, M; Phillips, R, 2000)
"The effect of the treatment of anal cancer by performing a high-dose-rate (HDR) brachytherapy boost during a short split between the external beam radiotherapy series (EBR) +/- chemotherapy was investigated."1.31Experience with split-course external beam irradiation +/- chemotherapy and integrated Ir-192 high-dose-rate brachytherapy in the treatment of primary carcinomas of the anal canal. ( Berger, A; Gebhart, FH; Geyer, E; Hebenstreit, J; Kapp, KS; Oechs, AC; Stoeger, H, 2001)
"We recently treated 2 patients with squamous cell carcinoma in the anal canal with bilateral inguinal nodal metastases using chemoradiotherapy."1.31[Two cases of squamous cell carcinoma of the anal canal treated with chemoradiotherapy]. ( Furutani, K; Fuwa, N; Kamata, M; Kodaira, T; Matsumoto, A; Sasaoka, M, 2001)
"Retrospective review of 50 MO anal cancer patients treated from 1984-1994."1.30Time-dose considerations in the treatment of anal cancer. ( Constantinou, EC; Daly, W; DeLaney, TF; Fung, CY; Kaufman, DS; Willett, CG, 1997)
"The standard treatment for anal cancer is combination chemo-radiotherapy."1.29The influence of age on the management of anal cancer. ( Basrur, V; de Gara, CJ; Figueredo, A; Goodyear, M; Knight, P, 1995)
"Four hundred five patients with anal cancer were identified by computer search, and 204 (51%) were evaluable; 164 of 204 (80%) had squamous cell carcinoma, 137 of whom (84%) were treated with sphincter-preserving procedures, and 27 of whom (16%) were treated by by radical surgery."1.29Recurrent squamous cell carcinoma of the anal canal. Predictors of initial treatment failure and results of salvage therapy. ( Coplin, MA; Johnson, FE; Longo, WE; Vernava, AM; Virgo, KS; Wade, TP, 1994)
"Among them, three patients had acquired immunodeficiency syndrome (AIDS)."1.29Squamous-cell carcinoma of the anus in HIV-positive patients. ( Berson, A; Chadha, M; Malamud, S; Pisch, J; Rosenblatt, EA, 1994)
"Seven patients had HIV, four of whom had acquired immunodeficiency syndrome."1.29Tolerance of patients with human immunodeficiency virus and anal carcinoma to treatment with combined chemotherapy and radiation therapy. ( Holland, JM; Swift, PS, 1994)
"The conventional surgical treatment of anal squamous cell carcinoma is abdominoperineal resection."1.29An alternative treatment of anal squamous cell carcinoma: combined radiotherapy and chemotherapy. ( Changchien, CR; Chen, JS; Fan, HA; Hsu, KC; Tang, R; Wang, JY; You, YT, 1993)
"Results of 21 cases of squamous cell carcinoma of anal canal treated by continuous infusion of 5-fluorouracil 1000 mg/sqm for 4 days and mitomycin-C 15 mg/sqm on 1st day by i."1.29Management of carcinoma anal canal with combination chemotherapy and concurrent radiotherapy. ( Mishra, RC; Sai, PL; Senapati, S, 1996)
" Radiotherapy is often combined with concurrent chemotherapy although no firm evidence exists that such combinations are more effective than radiotherapy alone."1.28Induction chemotherapy with carboplatin and 5-fluorouracil in combination with radiotherapy in loco-regionally advanced epidermoid carcinoma of the anus--preliminary results. ( Goldman, S; Kaigas, M; Svensson, C, 1992)
"Between 1979 and 1988, 33 patients with squamous cell carcinoma of the anal canal were treated with chemoradiation."1.28Squamous cell carcinoma of the anal canal. ( Fleshman, JW; Fry, RD; Halverson, JD; Kodner, IJ; Lopez, MJ; Monafo, WW; Myerson, RJ; Shapiro, SJ, 1991)
"A 62-year-old female with anal cancer underwent Miles operation in November, 1987."1.28[Effects of intra-arterial infusion chemotherapy in local recurrence of anal cancer]. ( Amino, K; Mieno, K; Miura, S; Satoi, Y; Shikata, J; Takeda, Y, 1989)
"We report preliminary results on treatment of anal carcinoma by radiotherapy and chemotherapy."1.28[Anal neoplasms. Treatment with radiotherapy and exclusive chemotherapy]. ( Armando, S; Arraztoa, J; Morales, Y; San Martín, S, 1989)
"Seventy patients with squamous cell carcinoma or cloacogenic carcinoma of the anus treated from 1979-1987 were reviewed."1.28Radiotherapy for anal cancer: experience from 1979-1987. ( Ajani, JA; Delclos, L; Hughes, LL; Martin, RG; Rich, TA, 1989)
"Twenty-eight patients with squamous cell carcinoma of the anal canal were treated by preoperative radiation therapy and chemotherapy."1.27Combined preoperative radiation and chemotherapy for squamous cell carcinoma of the anal canal. ( Considine, B; Kinzie, JJ; Leichman, L; Nigro, ND; Seydel, HG; Vaitkevicius, VK, 1983)
" During the first week of radiotherapy, 5-fluorouracil (1000 mg/m2 daily for four days by continuous infusion), and mitomycin (10 mg/m2 on day 1) were administered; four weeks later, a second cycle at the same dosage followed."1.27[Function-preserving treatment of anal cancer using simultaneous radio- and chemotherapy]. ( Dunst, J; Reichard, U; Sauer, R; Wolf, N, 1987)
"For many years surgery has been the treatment of choice for squamous cell carcinoma of the anus, but it is now becoming apparent that well-planned definitive radiation therapy combined with chemotherapy may obviate the need for an abdomino-perineal resection."1.27The use of radiation therapy combined with chemotherapy in the management of squamous cell carcinoma of the anus and marginally resectable adenocarcinoma of the rectum. ( Sischy, B, 1985)
"Treatment with Semustine (Methyl-CCNU) resulted in a partial response lasting 15 months."1.26Response of metastatic cloacogenic carcinoma to treatment with semustine. ( Wampler, GL; Zimm, S, 1981)
"In a 74-year-old man extramammary Paget's disease of the scrotal and perianal areas masqueraded as tinea cruris and chronic dermatitis for 7 years before it was diagnosed."1.26Extramammary Paget's disease. ( Goodall, J; Haberman, HF; Llewellyn, M, 1978)
"A fourth patient with previously treated epidermoid carcinoma of the anus presented with biopsy-proven pulmonary metastasis and was placed on the chemotherapeutic regimen alone."1.26Multi-modality therapy for epidermoid carcinoma of the anus. ( Newman, HK; Quan, SH, 1976)

Research

Studies (425)

TimeframeStudies, this research(%)All Research%
pre-199052 (12.24)18.7374
1990's81 (19.06)18.2507
2000's86 (20.24)29.6817
2010's169 (39.76)24.3611
2020's37 (8.71)2.80

Authors

AuthorsStudies
Nilsson, MP2
Gunnlaugsson, A2
Johnsson, A4
Scherman, J2
Guerra, GR1
Kong, JC1
Millen, RM1
Read, M1
Liu, DS1
Roth, S1
Sampurno, S1
Sia, J1
Bernardi, MP1
Chittleborough, TJ1
Behrenbruch, CC1
Teh, J1
Xu, H1
Haynes, NM1
Yu, J1
Lupat, R1
Hawkes, D1
Di Costanzo, N1
Tothill, RW1
Mitchell, C1
Ngan, SY3
Heriot, AG1
Ramsay, RG1
Phillips, WA1
Tchelebi, LT1
Eng, C5
Messick, CA2
Hong, TS4
Ludmir, EB3
Kachnic, LA10
Zaorsky, NG1
Stouvenot, M1
Meurisse, A2
Saint, A3
Buecher, B4
André, T3
Samalin, E4
Jary, M4
El Hajbi, F3
Baba-Hamed, N4
Pernot, S2
Kaminsky, MC1
Bouché, O3
Desrame, J3
Zoubir, M2
Smith, D3
Ghiringhelli, F2
Parzy, A3
de la Fouchardiere, C3
Almotlak, H1
Vienot, A2
Jacquin, M3
Taieb, J2
Nguyen, T3
Vernerey, D4
Borg, C7
Kim, S8
Johansson, M1
Axelsson, A1
Haglind, E1
Bock, D1
Angenete, E1
Radka, L1
Zdeňka, P1
Holliday, EB2
Morris, VK1
Johnson, B1
Das, P6
Minsky, BD4
Taniguchi, C1
Smith, GL1
Koay, EJ2
Koong, AC4
Delclos, ME1
Skibber, JM3
Rodriguez-Bigas, MA2
You, YN2
Bednarski, BK1
Tillman, MM1
Chang, GJ3
Jennings, K1
Citrin, D1
Valle, L1
Camphausen, K1
Cooley-Zgela, T1
Smart, D1
Yao, M1
Mitchell, JB1
Thompson, W1
Sereti, I1
Uldrick, T1
Neelis, KJ1
Kip, DM1
Speetjens, FM1
van der Linden, YM1
Lohynská, R2
Pechačová, Z1
Delhiat, AC1
Combet-Curt, V1
Vendrely, V6
Valery, M1
Cervantes, B1
Smolenschi, C1
Boilève, A1
Boige, V1
Malka, D2
Hollebecque, A1
Ducreux, M4
Patel, C1
Elmasry, A1
Giridharan, S1
Murofushi, KN1
Itasaka, S1
Shimokawa, M1
Murakami, Y1
Yamamoto, T1
Nishimura, Y1
Kudo, S1
Sakamoto, T1
Ariga, T1
Ogo, E1
Taguchi, K1
Jingu, K1
Ogawa, K1
Kharofa, JR4
Yothers, G3
Ajani, J5
Meyer, JE3
Augspurger, ME3
Okawara, GS4
Garg, MK4
Schefter, TE5
Swanson, TA3
Doncals, DE4
Kim, H3
Zaki, BI3
Narayan, S4
Lee, RJ3
Mamon, HJ3
Schwartz, MA3
Moughan, J9
Crane, CH10
Lukovic, J3
Hosni, A3
Liu, A3
Chen, J3
Tadic, T3
Patel, T3
Li, K3
Han, K3
Lindsay, P3
Craig, T3
Brierley, J3
Barry, A3
Wong, R3
Ringash, J3
Dawson, LA3
Kim, JJ3
Kumar, V2
Bansal, S2
Badola, A2
Nautiyal, V2
Gupta, M2
Ahmad, M2
Saini, S2
Matsuki, G1
Nakajima, T1
Ichise, N1
Nomura, K1
Fujikawa, M1
Kasai, M1
Okamoto, R1
Ikuta, S1
Nakamoto, Y1
Aihara, T1
Kajimoto, N1
Kakuno, A1
Yanagi, H1
Yamanaka, N1
Lemanski, C5
Pommier, P2
LE Malicot, K1
Rivin Del Campo, E2
Regnault, P1
Ronchin, P1
Crehange, G4
Tougeron, D2
Menager-Tabourel, E1
Diaz, O1
Hummelsberger, M1
Minsat, M2
Drouet, F1
Larrouy, A1
Peiffert, D11
Lievre, A1
Zasadny, X1
Hautefeuille, V1
Mornex, F3
Lepage, C1
Quero, L1
Schlosser, S1
Zalmanov, S1
Pfeffer, RM1
Lipski, Y1
Grinberg, V1
Kalmus, Y1
Levin, D1
Hod, K1
Ben David, MA1
Gul, SK1
Tepetam, H1
Yildiz, F2
Er, I1
Oksuz, DC1
Parvizi, M1
Ozden, AS1
Alicikus, ZA1
Sari, SY1
Alomari, O1
Gorken, IB1
Mineur, L2
Vazquez, L1
Belkacemi, M1
Toullec, C1
Bentaleb, N1
Boustany, R1
Plat, F1
Evesque, L2
Falk, AT2
Cavaglione, G3
Montagne, L1
Benezery, K4
Francois, E10
Agarwal, MS1
Hitchcock, KE1
Morris, CG3
George, TJ2
Mendenhall, WM4
Zlotecki, RA4
Matzinger, O3
Haustermans, K2
Glynne-Jones, R13
Winter, KA5
Konski, AA1
Ajani, JA13
Bosset, JF6
Hannoun-Levi, JM6
Puyraveau, M3
Chakravarthy, AB2
Meadows, H3
Northover, J2
Collette, L2
Christiaens, M1
Maingon, P4
Moreau, E1
Schmutz, JL1
Granel-Brocard, F1
Bursztejn, AC1
de Meric de Bellefon, M1
Castan, F1
Mazard, T1
Lenglet, A1
Demontoy, S1
Riou, O1
Llacer-Moscardo, C1
Fenoglietto, P2
Aillères, N1
Thezenas, S1
Debrigode, C1
Vieillot, S2
Gourgou, S1
Azria, D2
Sauter, M1
Lombriser, N1
Bütikofer, S1
Keilholz, G1
Kranzbühler, H1
Heinrich, H1
Rogler, G1
Vavricka, SR1
Misselwitz, B1
Raphael, MJ1
Ko, G1
Booth, CM1
Brogly, SB1
Li, W1
Kalyvas, M1
Hanna, TP1
Patel, SV1
Bidard, FC3
Dahan, L1
Rebucci-Peixoto, M1
Spehner, L3
Kouzy, R1
Abi Jaoude, J1
Lin, D1
El Alam, MB1
Klopp, AH1
Colbert, LE1
Taniguchi, CM1
Leiker, AJ1
Wang, CJ1
Sanford, NN1
Aguilera, TA1
Karri, S1
Beg, MS1
Kazmi, SA1
Olson, C1
Matthews, JA1
Abdelnaby, A1
Meyer, JJ2
Folkert, MR1
Nýdlová, A1
Drbohlavová, T1
Mazaná, E1
Jirkovská, M1
Veselský, T1
Malinová, B1
Stankušová, H1
Adotevi, O1
Abdeljaoued, S1
Rao, S2
Singh, K1
Sathyamurthy, A1
Ramireddy, JK1
Ram, TS1
Cabel, L1
Lightner, AL1
Vaidya, P1
McMichael, J1
Click, B1
Regueiro, M1
Steele, SR1
Hull, TL1
Astaras, C1
Bornand, A1
Koessler, T3
Olsen, JR2
Myerson, R4
Abitbol, A1
Johnson, D2
Chen, Y1
Fisher, B1
Michalski, J1
Chang, A2
Kachnic, L2
Zimmermann, M1
Beer, J1
Bodis, S1
von Moos, R1
Vlachopoulou, V1
Zwahlen, DR1
Oehler, C3
Coen, M1
Rigamonti, F1
Roth, A4
Follana, P3
Tuan Falk, A1
Doyen, J3
Reure, J1
Suzuki, N1
Azami, A1
Todate, Y1
Tada, T1
Waragai, M1
Honda, M1
Sato, A1
Takano, Y1
Abe, T1
Nakamura, T1
Teranishi, Y1
Dumont, S1
Louvet, C1
Bachet, JB1
Abdelghani, MB1
Aparicio, T1
Bennouna, J1
Gornet, JM2
Bonnetain, F2
Smith, CA1
Cacheux, W1
Puppa, G1
Fernandez, E1
Ho, L1
Dietrich, PY1
Zilli, T3
Allal, AS8
Roche, B2
Ris, F2
Savale, L1
Chaumais, MC1
Dorfmuller, P1
Humbert, M1
Montani, D1
Franco, P6
Montagnani, F1
Arcadipane, F6
Casadei, C1
Andrikou, K1
Martini, S2
Iorio, GC2
Scartozzi, M1
Mistrangelo, M7
Fornaro, L1
Cassoni, P7
Cascinu, S1
Ricardi, U7
Casadei Gardini, A3
Safran, H2
Leonard, KL1
Perez, K1
Vrees, M1
Klipfel, A1
Schechter, S1
Oldenburg, N1
Roth, L1
Shah, N1
Rosati, K1
Rajdev, L2
Mantripragada, K1
Sheng, IY1
Barth, P1
DiPetrillo, TA1
Jones, CM1
Adams, R3
Downing, A2
Harrison, M2
Hawkins, M1
Sebag-Montefiore, D12
Gilbert, DC1
Muirhead, R1
Sclafani, F1
Pittman, ME1
Milsom, J1
Yantiss, RK1
Ng, M1
Ho, H1
Skelton, J1
Guerrieri, M1
Guiney, M1
Chao, M1
Blakey, D1
Macleod, C1
Amor, H1
Subramanian, B1
Melven, L1
Faivre, JC1
Mirabel, X4
Stanbury, T1
Salleron, J1
Guillemin, F1
De Bari, B4
Lepinoy, A2
Ceccarelli, M1
Furfaro, G1
Valgiusti, M1
Passardi, A2
Trino, E1
Evangelista, A1
Esin, E1
Laçin, Ş1
Karakaş, Y1
Gültekin, M1
Dizdar, Ö1
Yalçın, Ş1
Mondaca, S1
Chatila, WK1
Bates, D1
Hechtman, JF1
Cercek, A1
Segal, NH1
Stadler, ZK1
Varghese, AM1
Kundra, R1
Capanu, M1
Shia, J1
Schultz, N1
Saltz, L1
Yaeger, R1
Elson, JK1
Ott, OJ1
Schmidt, M1
Semrau, S1
Strnad, V1
Matzel, KE2
Schneider, I1
Raptis, D1
Uter, W1
Grützmann, R1
Fietkau, R1
Yamaura, M1
Yamada, T2
Watanabe, R1
Kawai, H1
Hirose, S1
Tajima, H1
Sato, M1
Uchida, Y1
Suganuma, D1
Yamamoto, Y2
Moriwaki, T1
Hyodo, I1
Koerber, SA1
Seither, B1
Slynko, A1
Haefner, MF1
Krug, D1
Liermann, J1
Adeberg, S1
Herfarth, K1
Debus, J1
Sterzing, F1
Sato, H2
Koide, Y2
Shiota, M2
Mizuno, M1
Morise, Z1
Uyama, I1
Ladbury, C1
A Goodman, K1
Aoyama, Y1
Katada, T1
Saito, M1
Tsuchiya, T1
Nishido, T1
Kato, A1
Shibata, T2
Teranishi, F1
Sakamoto, S1
Mita, K1
Karamatsu, S1
Hikosaka, Y1
Nishida, T1
Martin, D2
Rödel, C9
Fokas, E3
Wo, JY2
Plastaras, JP1
Metz, JM1
Jiang, W1
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Drapek, LC2
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Baglini, C1
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Blaszkowsky, LS3
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Ben-Josef, E2
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Di Sibio, A1
Calvisi, G1
Lombardi, L1
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Di Staso, M1
Schietroma, M1
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van Noesel, CJ1
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Meadows, HM4
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Myint, AS1
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McDonald, A2
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Leslie, M3
Falk, S3
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Ledermann, J2
Kadalayil, L1
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Miglianico, L1
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Malekzadeh, K1
Paris, E1
Juzyna, B1
Ezra, P1
Gunderson, LL4
Pedersen, JE2
Benson, AB7
Mayer, RJ5
Haddock, MG5
Rich, TA6
Willett, CG7
Mansi, L1
Benzidane, B1
Cazorla, A1
Demarchi, M1
Kaliski, A1
Delabrousse, E1
Letondal, P1
Valmary-Degano, S1
Bazan, JG4
Luxton, G2
Kozak, MM1
Anderson, EM1
Hancock, SL1
Kapp, DS3
Kidd, EA1
Chang, DT4
Bejarano, PA1
Boutros, M1
Berho, M1
Oashi, K1
Tsutsumida, A1
Namikawa, K1
Tanaka, R1
Omata, W1
Yamazaki, N1
Call, JA1
Prendergast, BM1
Jensen, LG1
Ord, CB1
Goodman, KA5
Jacob, R1
Mell, LK6
Jabbour, SK1
Miller, RC4
Foo, M2
Link, E2
Leong, T2
Chu, J2
Lee, MT2
Chander, S2
Tran, PK1
Tomaszewski, JM2
Michael, M2
Heriot, A2
Claren, A1
Frin, AC1
Mari, V1
Fraunholz, IB2
Haberl, A3
Klauke, S1
Gute, P1
Rödel, CM1
Capelli, L1
Ulivi, P1
Giannini, M1
Freier, E1
Tamberi, S1
Scarpi, E1
Zoli, W1
Ragazzini, A1
Amadori, D1
Frassineti, GL1
Buglione, M1
Maddalo, M1
Lestrade, L2
Spiazzi, L1
Vitali, P1
Barbera, F1
Magrini, SM1
Blinde, SE1
Schasfoort, R1
Mens, JW1
Verhoef, C1
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Kapp, KS2
Stuecklschweiger, G1
Berger, A2
Geyer, E2
Gall, FP2
Allal, A1
Kurtz, JM4
Pipard, G1
Marti, MC3
Miralbell, R1
Popowski, Y1
Egeli, R1
Tanum, G2
Karlsen, KO3
You, YT1
Wang, JY1
Changchien, CR1
Chen, JS1
Hsu, KC1
Tang, R1
Fan, HA1
O'Sullivan, B2
Wong, CS3
Catton, CN2
Roca, E1
Milano, MC1
Pennella, E1
Barugel, M1
Gualdrini, U1
Lumi, M1
Gonzalez, G1
Sardi, M1
Fleischer, I1
Graziano, A1
Lipsitz, SR2
Lefkopoulou, M1
Engstrom, PF1
Dayal, YY1
Cobau, CD1
Oken, MM1
Haller, DG1
Kaplan, EH1
Otteman, LA1
Schuchter, LM1
Sentenac, I1
Mahé, M1
Mishra, RC1
Senapati, S1
Sai, PL1
Pajak, TF2
Petrelli, N1
Doggett, S1
Quivey, J1
Kerman, H1
Coia, L1
Murray, K1
Bottomley, DM1
Aqel, N1
Selvaratnam, G1
Phillips, RH1
Doci, R2
Zucali, R2
La Monica, G1
Meroni, E1
Kenda, R1
Eboli, M1
Lozza, L1
Adamietz, IA1
Lorenz, M1
Staib-Sebler, E1
Böttcher, HD1
Bartelink, H1
Eschwege, F2
Rougier, P3
Gonzalez, DG1
van Glabbeke, M1
Pierart, M1
Seitz, JF2
Cvitkovic, F2
Nasca, S1
Lusinchi, A2
Debrigode, E1
Constantinou, EC1
Daly, W1
Fung, CY1
Kaufman, DS1
Valentini, V1
Morganti, AG1
Luzi, S1
Mantello, G1
Mantini, G1
Salvi, G1
Cellini, N1
Höcht, S1
Wiegel, T2
Kroesen, AJ1
Berdel, WE1
Runkel, N1
Hinkelbein, W1
Ayzac, L1
Hun, D1
Coquard, R1
Goldman, S2
Friberg, B1
Goldberg, ZI1
Chapman, WB2
Klamut, HJ1
Rauth, AM1
Obradovic, M1
Laurencet, F2
Spada, A1
Akpek, G1
Hartshorn, KL1
Bonin, SR1
Russell, AH1
Coia, LR1
Paris, KJ1
Sauter, ER1
Juturi, JV1
Francis, B1
Koontz, PW1
Wilkes, JD1
Hoffman, R1
Klencke, B1
Klas, JV1
Rothenberger, DA1
Wong, WD1
Madoff, RD1
Sprangers, MA1
Reymond, MA1
Tsao, MS1
Sharma, V1
Pintilie, M1
Faivre, C1
Mitry, E1
Lasser, P1
Elias, D1
Cleator, S1
Fife, K1
Phillips, R1
Manivit, P1
Polo, R1
Tabary, D1
Nabet, M1
Polo, M1
Adamy, M1
Rubini, B1
Fromaget, JM1
Chipponi, PN1
Untereiner, M1
Indinnimeo, M1
Cicchini, C1
Stazi, A1
Giarnieri, E1
Limiti, MR1
Ghini, C1
Vecchione, A1
Berney, CR1
Rohner, S1
Aapro, MS1
Alberto, P1
Brown, RS1
McCormack, M1
Lankester, KJ1
Spittle, MF1
Pehoushek, J1
Smith, KJ1
Gebhart, FH1
Oechs, AC1
Hebenstreit, J1
Stoeger, H1
Mitchell, SE1
Carroll, RR1
Sasaoka, M1
Fuwa, N1
Matsumoto, A1
Furutani, K1
Kamata, M1
Kodaira, T1
Khoubehi, B1
Schofield, A1
Slevin, ML1
Talbot, IC1
Giovannini, M2
Michel, P1
Luporsi, E1
Weber, DC1
Vordermark, D2
Flentje, M2
Sailer, M2
Kölbl, O2
Thiede, A1
Grieger, J1
Lachmann, R1
Bohrer, M1
Tiefenbacher, U1
Haberman, HF1
Goodall, J1
Llewellyn, M1
Bruckner, HW1
Spigelman, MK1
Mandel, E1
Cohen, C1
Deppe, G1
Turell, R1
Schiavone, J1
Kolleg, MK1
Moore, GE1
Norton, LW1
Meiselbaugh, DM1
Hajdu, SI1
Sturm, JT1
Christenson, CE1
Uecker, JH1
Perry, JF1
Newman, HK1
Reck, T1
Köckerling, F1
Kaigas, M1
Norum, J1
Wist, E1
Sfedj, D1
Houvenaeghel, G1
Bombelli, L1
Montalto, F1
Lamonica, G1
Krebs, HB1
Lopez, MJ1
Fry, RD1
Halverson, JD1
Monafo, WW1
Epperson, WJ1
Bugat, R1
Sommer, K1
Brockmann, WP1
Krüll, A1
Birk, S1
Lange, CS1
Papillon, J1
Thirlby, RC1
Hammer, CJ1
Galagan, KA1
Travaglini, JJ1
Picozzi, VJ1
Kuzel, T1
Esparaz, B1
Green, D1
Kies, M1
Hughes, L1
Brock, W1
Mieno, K1
Satoi, Y1
Amino, K1
Miura, S1
Shikata, J1
Oberlin, P1
Crickx, B1
Picard, C1
Benhamou, G1
Vilotte, J1
Vissuzaine, C1
Bilbault, P1
Belaïch, S1
Habr-Gama, A1
da Silva e Sousa Júnior, AH1
Nadalin, W1
Gansl, R1
da Silva, JH1
Pinotti, HW1
Fosså, SD2
Flokkmann, A2
Guldvog, I1
Haffner, J1
Wolf, N2
San Martín, S1
Armando, S1
Arraztoa, J1
Morales, Y1
Carrasco, CH1
Jackson, DE1
Wallace, S1
Hughes, LL1
Delclos, L1
Martin, RG1
Doggett, RL1
Krall, JM1
Taylor, DG1
Sause, WT1
Lipsett, JA1
Tjandra, J1
Sillman, FH1
Sedlis, A1
Boyce, JG1
Muff, NS1
Shetabi, H1
Wittlinger, P1
Podolsky, W1
Padmanabhan, A1
Dobrowsky, W1
John, MJ2
Lovalvo, L1
Secco, GB1
Sertoli, MR1
Scarpati, D1
Marino, G1
Fardelli, R1
Nobile, MT1
Wade, J1
Reichard, U1
Denecke, H1
Roloff, R1
Peppe, H1
Bianchi, C1
Bianchi, O1
Stringa, S1
Schmidt, KU1
Wiskemann, A1
Mensing, H1
Khater, R1
Frenay, M1
Bourry, J1
Milano, G1
Namer, M1
Nigro, N1
Buroker, T1
Bradley, G1
Olchowski, S1
Cummings, G1
Leichman, C1
Smith, RA1
Stubblefield, GC1
Brock, DT1
Reagan, MT1
Greenall, MJ1
Urmacher, C1
DeCosse, JJ1
Fischerman, K1
Briand, P1
Olsen, J1
Nielsen, OV1

Clinical Trials (21)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of the Clinical Value of a Docetaxel, Cisplatin and 5-fluorouracil (DCF) Strategy Adapted to Patients for the Management of Metastatic or Locally Advanced Anal Resistant Radiochemotherapy Squamous Cell Anal Carcinoma.[NCT02402842]Phase 270 participants (Actual)Interventional2014-09-30Completed
Spartalizumab, mDCF (Docetaxel, Cisplatin and 5-fluorouracil) and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma. A Phase IIA Study[NCT04894370]Phase 234 participants (Anticipated)Interventional2022-06-09Recruiting
A Non-comparative Randomized 2:1 Phase II Study of Docetaxel, Cisplatin, and 5-fluorouracil in Combination or Not With Atezolizumab in Patients With Metastatic or Unresectable Locally Advanced Squamous Cell Anal Carcinoma[NCT03519295]Phase 299 participants (Anticipated)Interventional2018-07-22Active, not recruiting
Neoadjuvant PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced Anal Canal Squamous Carcinoma Patients[NCT05060471]Phase 227 participants (Anticipated)Interventional2021-09-08Enrolling by invitation
Immunomonitoring and Biomarker Research Based on Tumor and Blood Samples in Patients With Squamous Cell Anal Carcinoma[NCT03942900]0 participants (Actual)Observational2020-04-01Withdrawn (stopped due to Study not submitted to regulatory authorities)
Randomized Trial to Evaluate Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy[NCT02369939]Phase 3118 participants (Anticipated)Interventional2014-12-31Recruiting
A Pilot Feasibility Study of Definitive Concurrent Chemoradiation With Pencil Beam Scanning Proton Beam in Combination With 5-Fluorouracil and Mitomycin-C for Carcinoma of the Anal Canal[NCT01858025]Early Phase 125 participants (Actual)Interventional2013-07-31Active, not recruiting
Efficacy and Safety of Topical Trichloroacetic Acid vs. Electrocautery for the Treatment of Anal Intraepithelial Neoplasia in HIV-positive Patients (TECAIN) - a Randomized Controlled Trial[NCT02615860]560 participants (Actual)Interventional2015-11-30Completed
Study of Pomalidomide in Anal Cancer Precursors (SPACE): a Phase 2 Study of Immunomodulation in People With Persistent HPV-associated High Grade Squamous Intraepithelial Lesions[NCT03113942]Phase 226 participants (Actual)Interventional2017-06-14Active, not recruiting
A Multicenter Observational and Feasibility Study of Excision of Superficially Invasive Squamous Cell Carcinoma (SISCCA) of the Anal Canal and Perianus in HIV-Infected Persons[NCT02437851]Phase 216 participants (Actual)Interventional2015-04-30Active, not recruiting
A Phase II, Randomised Study of Nivolumab as Consolidation Therapy in Patients With Locally Advanced, Unresectable Non-Small Cell Lung Cancer (Stage III) Who Have Not Progressed Following Neoadjuvant Chemotherapy Plus Nivolumab and Definitive Concurrent C[NCT04085250]Phase 2264 participants (Actual)Interventional2019-11-28Active, not recruiting
A Randomized Phase II Study of the Administration of Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy for Patients With Squamous Cell Carcinoma of the Anal Canal (BISQUIT)[NCT03870607]Phase 275 participants (Anticipated)Interventional2019-03-13Recruiting
Study of the Association Between Tumor Microenvironment Macrophages and Treatment Response in Squamous Cell Carcinoma of the Anal Canal[NCT05019235]154 participants (Actual)Observational2021-08-05Active, not recruiting
Tumor Recurrence After Abdominal-perineal Amputation in Squamous Cell Carcinoma of the Anus[NCT05201105]43 participants (Actual)Observational2021-10-15Completed
A Phase 3, Multicenter, Double-Blind Randomized Study of Mitomycin, 5-Fluorouracil and IMRT Combined With or Without Anti-PD-1 in Patients With Locally Advanced Anal Canal Squamous Carcinoma[NCT05374252]Phase 3102 participants (Anticipated)Interventional2022-05-07Recruiting
Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0[NCT01621217]Phase 121 participants (Anticipated)Interventional2012-06-30Completed
Phase II Trial of Combined Modality Therapy Plus Cetuximab in HIV-Associated Anal Carcinoma[NCT00324415]Phase 245 participants (Actual)Interventional2006-09-30Completed
A Phase III Randomized Study of 5-Fluorouracil, Mitomycin-C, and Radiotherapy Versus 5-Fluorouracil, Cisplatin, and Radiotherapy in Carcinoma of the Anal Canal[NCT00003596]Phase 3682 participants (Actual)Interventional1998-10-31Completed
Continuous Fluorouracil Plus Mitomycin C Versus Mitomycin C Plus Cisplatin As Chemotherapy Combination In Combined Radiochemotherapy For Locally Advanced Anal Cancer. A Phase II-III Study[NCT00068744]Phase 2/Phase 388 participants (Actual)Interventional2003-07-31Terminated (stopped due to low accrual)
Observational Study of Functional Outcomes After Chemoradiotherapy for Squamous Cell Cancer of the Anus[NCT01853059]176 participants (Anticipated)Observational2013-10-31Not yet recruiting
A Prospective Phase II Study of Prophylactic TPO Combined With Bone Marrow-Sparing Intensity-Modulated Radiotherapy to Reduce Platelet Inhibition in Patients With Esophageal Cancer Undergoing Concurrent Chemoradiotherapy[NCT05944809]Phase 227 participants (Anticipated)Interventional2023-07-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in CD4 Counts During and for 1 Year After Completion of Study Treatment

Change in absolute CD4 counts from start of treatment to 1 year after completion of study treatment (NCT00324415)
Timeframe: 1 year following treatment discontinuation

Interventioncells/mm3 (Median)
Combined Modality Therapy102

Colostomy-free Survival at 1 Year

Percentage of participants who are alive and have not had a colostomy (NCT00324415)
Timeframe: 1 year

Interventionpercentage of participants (Number)
Combined Modality Therapy92.4

Incidence of Opportunistic Illnesses

Incidence of opportunistic illnesses, including the development of AIDS during and for 1 year after completion of study treatment (NCT00324415)
Timeframe: 1 year following treatment discontinuation

Interventionparticipants (Number)
Combined Modality Therapy4

Local Failure Rate at 3 Years

Patients will be classified into two groups for purposes of primary endpoint analysis: failure or no failure at 3 years (in the primary analysis, patients lost to follow-up prior to 3 years will be considered failures). For the secondary endpoint of objective response, patients will be classified as responders (NCT00324415)
Timeframe: 3 years following treatment discontinuation

Interventionparticipants (Number)
Combined Modality Therapy23

Objective Response Rate (Complete and Partial)

Number of participants with complete and partial responses based on the RECIST criteria (NCT00324415)
Timeframe: 3 years following treatment discontinuation

Interventionparticipants (Number)
Combined Modality Therapy30

Overall Survival

Percentage of participants who are alive at one year (NCT00324415)
Timeframe: 1 year

Interventionpercentage of participants (Number)
Combined Modality Therapy92.8

Progression-free Survival

Progression-free survival at 1 year is the percentage of patients who are alive and have not experienced progressive disease, defined as at least a 20% increase in the sum of the longest diameter of target lesions, taking as reference the smallest sum longest diameter recorded since the treatment started, or the appearance of one or more new lesions. (NCT00324415)
Timeframe: 1 year

Interventionpercentage of participants (Number)
Combined Modality Therapy87.3

Quality of Life

EORTC QLQ-C30 Global Score at 1 year. The EORTC QLQ-C30 is a validated questionnaire that evaluates quality of life. The global score is an overall score for quality of life that ranges from 0 to 100. Higher scores indicate between quality of life (NCT00324415)
Timeframe: 1 year

Interventionunits on a scale (Mean)
Combined Modality Therapy78.9

Relapse-free Survival

Percentage of participants who are alive and have not experienced progressive disease and have not relapsed (NCT00324415)
Timeframe: 1 year

Interventionpercentage of participants (Number)
Combined Modality Therapy83.1

Toxicity

Delayed toxicities are defined as toxicities that occur over 90 days following treatment completion (NCT00324415)
Timeframe: 90 days following treatment discontinuation

Interventionevents (Number)
Combined Modality Therapy5

Reviews

41 reviews available for fluorouracil and Anal Cancer

ArticleYear
[Anal cancer: Focus on current treatment and future perspective].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2022, Volume: 26, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2022
Comparison of intravenous 5-Fluorouracil with Oral Capecitabine in the Treatment of Anal Squamous Cell Carcinoma Using Modern Radiation Techniques.
    The Israel Medical Association journal : IMAJ, 2023, Volume: 25, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; Carcinoma, Squamous Ce

2023
Pooled Analysis of external-beam RADiotherapy parameters in phase II and phase III trials in radiochemotherapy in Anal Cancer (PARADAC).
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 121

    Topics: Anus Neoplasms; Chemoradiotherapy; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as

2019
[Squamous cell anal carcinoma. What's next ?]
    Bulletin du cancer, 2021, Volume: 108, Issue:1

    Topics: Alphapapillomavirus; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carboplatin; Ca

2021
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
    ESMO open, 2021, Volume: 6, Issue:4

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Fluorouracil; Humans; Rectal Neoplasms

2021
Randomized Clinical Trials in Localized Anal Cancer.
    Surgical oncology clinics of North America, 2017, Volume: 26, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcino

2017
Anal Cancer in the Era of Dose Painted Intensity Modulated Radiation Therapy: Implications for Regional Nodal Therapy.
    Seminars in radiation oncology, 2019, Volume: 29, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Diagnostic Imagin

2019
Chemoradiotherapy for anal cancer: are we as good as we think?
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019, Volume: 195, Issue:5

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Cohort Studies; Combined Modality Thera

2019
[Brachytherapy for anal cancers].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2013, Volume: 17, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachytherapy; Carcinoma, Squamous C

2013
Anal squamous intraepithelial neoplasia.
    Gastroenterology clinics of North America, 2013, Volume: 42, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Antimetabolites, Antineoplastic; A

2013
Anal cancer treatment: current status and future perspectives.
    World journal of gastroenterology, 2015, Feb-28, Volume: 21, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; C

2015
Advances in the Management of Anal Cancer.
    Current oncology reports, 2016, Volume: 18, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; Cisplatin; Female; Flu

2016
Treatment of the Primary Tumor in Anal Canal Cancers.
    Surgical oncology clinics of North America, 2017, Volume: 26, Issue:1

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2017
Evolution and Management of Treatment-Related Toxicity in Anal Cancer.
    Surgical oncology clinics of North America, 2017, Volume: 26, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2017
Capecitabine in locally advanced anal cancer, do we need randomised evidence?
    Expert review of anticancer therapy, 2017, Volume: 17, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cap

2017
Current management of anal canal cancer.
    Current oncology reports, 2009, Volume: 11, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fluoroura

2009
Intensity-modulated radiation therapy for anal cancer.
    Oncology (Williston Park, N.Y.), 2009, Nov-15, Volume: 23, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Combined Modality Therapy

2009
Anal carcinoma therapy: can we improve on 5-fluorouracil/mitomycin/radiotherapy?
    Journal of the National Comprehensive Cancer Network : JNCCN, 2010, Volume: 8, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fluoroura

2010
[Radiochemotherapy for locally advanced anal cancer].
    Onkologie, 2010, Volume: 33 Suppl 4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2010
Management of anal cancer in 2010. Part 2: current treatment standards and future directions.
    Oncology (Williston Park, N.Y.), 2010, Apr-30, Volume: 24, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2010
Combined-modality treatment for anal cancer: current strategies and future directions.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy, Adjuvant; Cisplatin; C

2010
[Management of anal canal carcinoma].
    Revue medicale suisse, 2011, May-25, Volume: 7, Issue:296

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2011
[Should the treatment of anal carcinoma be adapted in the elderly? A retrospective analysis of acute toxicities in a French centre and a review of the literature].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2012, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachythera

2012
[A case of perianal squamous cell carcinoma attaining a complete response over five years with chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Anus Neoplasms; Biopsy; Carcinoma, Squ

2011
Treatment options for anal intraepithelial neoplasia and evidence for their effectiveness.
    Sexual health, 2012, Volume: 9, Issue:6

    Topics: Adult; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Anus Neoplasms; Cido

2012
Squamous cell carcinoma of the anal margin.
    Journal of surgical oncology, 2004, May-01, Volume: 86, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2004
[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2004
Chemotherapeutic options in the management of anal cancer.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:12

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Fluorouracil; HIV Se

2004
Lipodermatosclerosis as a form of vascular compromise-associated radiation recall dermatitis: case report and a review of literature.
    Journal of cutaneous pathology, 2006, Volume: 33 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2006
Current treatment for localized anal carcinoma.
    Current opinion in oncology, 2007, Volume: 19, Issue:4

    Topics: Antineoplastic Agents; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Humans; Mi

2007
Synchronous chemotherapy and radiotherapy for carcinoma of the anal canal--an alternative to abdominoperineal resection.
    The Australian and New Zealand journal of surgery, 1984, Volume: 54, Issue:2

    Topics: Abdomen; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous C

1984
Combination therapy for epidermoid carcinoma of the anal canal.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1994
Interstitial hyperthermia and high dose rate brachytherapy in the treatment of anal cancer: a phase I/II study.
    International journal of radiation oncology, biology, physics, 1994, Jan-01, Volume: 28, Issue:1

    Topics: Adult; Aged; Anus Neoplasms; Brachytherapy; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell;

1994
[Cancer of the anal canal].
    Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique, 1990, Volume: 77, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineopl

1990
Anal canal cancer: current treatment and results.
    Annals of the Academy of Medicine, Singapore, 1996, Volume: 25, Issue:3

    Topics: Anal Canal; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Ant

1996
[Chemoradiotherapy in treatment of cancer of the anal canal].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 1998, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy,

1998
Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

1999
Malignant tumors of the anal canal: the spectrum of disease, treatment, and outcomes.
    Cancer, 1999, Apr-15, Volume: 85, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus

1999
[Radiochemotherapy in anal canal epidermoid cancer].
    Annales de chirurgie, 2000, Volume: 125, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2000
Concomitant radiotherapy and chemotherapy for anal cancer.
    Seminars in oncology, 1992, Volume: 19, Issue:4 Suppl 11

    Topics: Anus Neoplasms; Bleomycin; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Mitomycins

1992
A review of lower genital intraepithelial neoplasia and the use of topical 5-fluorouracil.
    Obstetrical & gynecological survey, 1985, Volume: 40, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Anal Canal; Anus Neoplasms; Carc

1985

Trials

76 trials available for fluorouracil and Anal Cancer

ArticleYear
Capecitabine in the treatment of anal squamous cell carcinoma.
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2022,Winter, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; Carcinoma, Squamous Ce

2022
Pilot trial of topical MTS‑01 application to reduce dermatitis in patients receiving chemoradiotherapy for stage I‑III carcinoma of the anal canal.
    International journal of oncology, 2022, Volume: 60, Issue:6

    Topics: Anal Canal; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Dermatitis; Fluorouracil; H

2022
A phase II study of concurrent chemoradiotherapy with 5-fluorouracil and mitomycin-C for squamous cell carcinoma of the anal canal (the JROSG 10-2 trial).
    Journal of radiation research, 2023, Jan-20, Volume: 64, Issue:1

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2023
Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial.
    BMC cancer, 2020, Apr-25, Volume: 20, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neopla

2020
Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial.
    BMC cancer, 2020, Apr-25, Volume: 20, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neopla

2020
Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial.
    BMC cancer, 2020, Apr-25, Volume: 20, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neopla

2020
Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial.
    BMC cancer, 2020, Apr-25, Volume: 20, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neopla

2020
Anti-Telomerase CD4
    International journal of molecular sciences, 2020, Sep-17, Volume: 21, Issue:18

    Topics: Adaptive Immunity; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; A

2020
Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD groups (Epitopes-HPV02 study).
    BMC cancer, 2017, Aug-25, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2017
Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD groups (Epitopes-HPV02 study).
    BMC cancer, 2017, Aug-25, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2017
Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD groups (Epitopes-HPV02 study).
    BMC cancer, 2017, Aug-25, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2017
Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD groups (Epitopes-HPV02 study).
    BMC cancer, 2017, Aug-25, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2017
Prognostic factors of colostomy free survival in patients presenting with locally advanced anal canal carcinoma: A pooled analysis of two prospective trials (KANAL 2 and ACCORD 03).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 129, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

2018
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infec

2013
Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; C

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2013
[Concurrent radiochemotherapy with 5-FU/mitomycin remains standard treatment for anal carcinoma. Long-term results of the phase III RTOG 98-11 trial].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013, Volume: 189, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Cisplatin; Diseas

2013
Phase 1 study of cetuximab in combination with 5-fluorouracil, cisplatin, and radiotherapy in patients with locally advanced anal canal carcinoma.
    Cancer, 2013, Aug-15, Volume: 119, Issue:16

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2013
Dosimetric parameters predictive of acute gastrointestinal toxicity in patients with anal carcinoma treated with concurrent chemotherapy and intensity-modulated radiation therapy.
    Oncology, 2013, Volume: 85, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Cisplatin;

2013
Unexpected toxicity of cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: results of the UNICANCER ACCORD 16 phase II trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Anus Neoplasms; Cetuximab; Chemoradiotherapy; Cispla

2013
Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial.
    International journal of radiation oncology, biology, physics, 2013, Nov-15, Volume: 87, Issue:4

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squ

2013
Impact of advancing age on treatment and outcomes in anal cancer.
    Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Ne

2014
Epigenomic characterization of locally advanced anal cancer: a radiation therapy oncology group 98-11 specimen study.
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2014
Intensity-modulated radiation therapy with simultaneous integrated boost combined with concurrent chemotherapy for the treatment of anal cancer patients: 4-year results of a consecutive case series.
    Cancer investigation, 2015, Volume: 33, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2015
Predictors of acute toxicities during definitive chemoradiation using intensity-modulated radiotherapy for anal squamous cell carcinoma.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:2

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Area Under Curve; Carcinoma,

2016
The Effect of the UK Coordinating Centre for Cancer Research Anal Cancer Trial (ACT1) on Population-based Treatment and Survival for Squamous Cell Cancer of the Anus.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2015, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2015
Prospective phase II study of tomotherapy based chemoradiation treatment for locally advanced anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2015
Phase II study of computed tomography-guided (125)I-seed implantation plus chemotherapy for locally recurrent rectal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachytherapy; Camptoth

2016
Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:18

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cetu

2015
Phase II Study of Capecitabine in Substitution of 5-FU in the Chemoradiotherapy Regimen for Patients with Localized Squamous Cell Carcinoma of the Anal Canal.
    Journal of gastrointestinal cancer, 2016, Volume: 47, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape

2016
Clinical outcome in patients treated with simultaneous integrated boost - intensity modulated radiation therapy (SIB-IMRT) with and without concurrent chemotherapy for squamous cell carcinoma of the anal canal.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; Carcinoma, Squamous Ce

2016
Efficacy and safety of helical tomotherapy with daily image guidance in anal canal cancer patients.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape

2016
Locally Advanced (T3-T4 or N+) Anal Cancer Treated with Simultaneous Integrated Boost Radiotherapy and Concurrent Chemotherapy.
    Anticancer research, 2016, Volume: 36, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradioth

2016
Patient reported quality of life after helical IMRT based concurrent chemoradiation of locally advanced anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 120, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2016
Cetuximab Plus Chemoradiotherapy for HIV-Associated Anal Carcinoma: A Phase II AIDS Malignancy Consortium Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Volume: 35, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2017
Cetuximab Plus Chemoradiotherapy in Immunocompetent Patients With Anal Carcinoma: A Phase II Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group Trial (E3205).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Volume: 35, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2017
Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811.
    International journal of radiation oncology, biology, physics, 2017, 03-01, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chem

2017
EGFR Inhibitors in Patients with Advanced Squamous Cell Anal Carcinomas: A Single-Institution Experience.
    Oncology, 2017, Volume: 92, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms;

2017
Mitomycin C with continuous fluorouracil or with cisplatin in combination with radiotherapy for locally advanced anal cancer (European Organisation for Research and Treatment of Cancer phase II study 22011-40014).
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:16

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2009
Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I).
    British journal of cancer, 2010, Mar-30, Volume: 102, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma; Fluorouracil; Follow-Up S

2010
Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I).
    British journal of cancer, 2010, Mar-30, Volume: 102, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma; Fluorouracil; Follow-Up S

2010
Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I).
    British journal of cancer, 2010, Mar-30, Volume: 102, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma; Fluorouracil; Follow-Up S

2010
Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I).
    British journal of cancer, 2010, Mar-30, Volume: 102, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma; Fluorouracil; Follow-Up S

2010
"Mind the gap"--the impact of variations in the duration of the treatment gap and overall treatment time in the first UK Anal Cancer Trial (ACT I).
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2011
Concurrent cisplatin, continuous infusion fluorouracil and radiotherapy followed by tailored consolidation treatment in non metastatic anal squamous cell carcinoma.
    BMC cancer, 2011, Feb-03, Volume: 11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2011
Long-term follow-up of a Phase II trial of high-dose radiation with concurrent 5-fluorouracil and cisplatin in patients with anal cancer (ECOG E4292).
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Benzodiazepines; Chemor

2011
Three cytotoxic drugs combined with pelvic radiation and as maintenance chemotherapy for patients with squamous cell carcinoma of the anus (SCCA): long-term follow-up of a phase II pilot study using 5-fluorouracil, mitomycin C and cisplatin.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 104, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2012
Prognostic factors for recurrence and survival in anal cancer: generating hypotheses from the mature outcomes of the first United Kingdom Coordinating Committee on Cancer Research Anal Cancer Trial (ACT I).
    Cancer, 2013, Feb-15, Volume: 119, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Female; Flu

2013
Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Dec-10, Volume: 30, Issue:35

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Cisplatin;

2012
RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 2013, May-01, Volume: 86, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Analysis of Variance; Antineoplastic Combined Chemothera

2013
Shortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastr
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Thera

2003
Contribution of conformal therapy in the treatment of anal canal carcinoma with combined chemotherapy and radiotherapy: results of a phase II study.
    International journal of radiation oncology, biology, physics, 2003, Jul-01, Volume: 56, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2003
Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy.
    Oncology, 2003, Volume: 65, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2003
[Epidermoid carcinomas of the anal canal treated with definitive radiation therapy in a series of 305 patients].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2003, Volume: 7, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2003
[Rationale and progress of the phase III trial: intensification of the treatment of locally advanced squamous cell carcinoma of the anal canal].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2003, Volume: 7 Suppl 1

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplasti

2003
Chemoradiotherapy combined with intracavitary hyperthermia for anal cancer: feasibility and long-term results from a phase II randomized trial.
    American journal of clinical oncology, 2005, Volume: 28, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Dia

2005
Topical 5-fluorouracil in the management of extensive anal Bowen's disease: a preferred approach.
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:3

    Topics: Administration, Topical; Adult; Aged; Antimetabolites, Antineoplastic; Anus Neoplasms; Biopsy; Bowen

2005
Effective treatment of anal cancer in the elderly with low-dose chemoradiotherapy.
    British journal of cancer, 2005, Apr-11, Volume: 92, Issue:7

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Sq

2005
Local tumor control and toxicity in HIV-associated anal carcinoma treated with radiotherapy in the era of antiretroviral therapy.
    Radiation oncology (London, England), 2006, Aug-18, Volume: 1

    Topics: Adult; Aged; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Anus Neoplasms; Combined

2006
Chemoradiotherapy with or without consolidation chemotherapy using cisplatin and 5-fluorouracil in anal squamous cell carcinoma: long-term results in 31 patients.
    BMC cancer, 2008, Jan-15, Volume: 8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.
    JAMA, 2008, Apr-23, Volume: 299, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisp

2008
Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08.
    International journal of radiation oncology, biology, physics, 2008, Sep-01, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colo

2008
EXTRA--a multicenter phase II study of chemoradiation using a 5 day per week oral regimen of capecitabine and intravenous mitomycin C in anal cancer.
    International journal of radiation oncology, biology, physics, 2008, Sep-01, Volume: 72, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus

2008
Induction therapy for poor-prognosis anal canal carcinoma: a phase II study of the cancer and Leukemia Group B (CALGB 9281).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jul-01, Volume: 26, Issue:19

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2008
[Treatment of condyloma acuminatum with 0.5% 5-fluorouracil-solution, A double-blind clinical trial].
    Zeitschrift fur Hautkrankheiten, 1982, Jun-01, Volume: 57, Issue:11

    Topics: Administration, Topical; Adolescent; Adult; Anus Neoplasms; Clinical Trials as Topic; Condylomata Ac

1982
Conservative management of squamous cell carcinoma of the anal canal.
    The Australian and New Zealand journal of surgery, 1994, Volume: 64, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1994
Combination therapy for epidermoid carcinoma of the anal canal.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1994
Interstitial hyperthermia and high dose rate brachytherapy in the treatment of anal cancer: a phase I/II study.
    International journal of radiation oncology, biology, physics, 1994, Jan-01, Volume: 28, Issue:1

    Topics: Adult; Aged; Anus Neoplasms; Brachytherapy; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell;

1994
Mitomycin in anal canal carcinoma.
    Oncology, 1993, Volume: 50 Suppl 1

    Topics: Actuarial Analysis; Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anu

1993
[Medical treatment of 44 patients with anal canal carcinoma. Argentinian Intergroup for the treatment of gastrointestinal tumors (IATTGI)].
    Medicina, 1995, Volume: 55, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; An

1995
Initial results of a phase II trial of high dose radiation therapy, 5-fluorouracil, and cisplatin for patients with anal cancer (E4292): an Eastern Cooperative Oncology Group study.
    International journal of radiation oncology, biology, physics, 1996, Jul-01, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Combined Modality Therapy

1996
Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

1996
Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.
    Lancet (London, England), 1996, Oct-19, Volume: 348, Issue:9034

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1996
Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.
    Lancet (London, England), 1996, Oct-19, Volume: 348, Issue:9034

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1996
Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.
    Lancet (London, England), 1996, Oct-19, Volume: 348, Issue:9034

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1996
Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.
    Lancet (London, England), 1996, Oct-19, Volume: 348, Issue:9034

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1996
Primary chemoradiation therapy with fluorouracil and cisplatin for cancer of the anus: results in 35 consecutive patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1996
Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colostomy; Combined Modality Therapy

1997
Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colostomy; Combined Modality Therapy

1997
Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colostomy; Combined Modality Therapy

1997
Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastro
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colostomy; Combined Modality Therapy

1997
Preliminary results of a phase II study of high-dose radiation therapy and neoadjuvant plus concomitant 5-fluorouracil with CDDP chemotherapy for patients with anal canal cancer: a French cooperative study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy, Adjuvant;

1997
Is chemoradiation feasible in elderly patients? A study of 17 patients with anorectal carcinoma.
    Cancer, 1997, Oct-15, Volume: 80, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Mo

1997
Treatment of anal canal carcinoma with high dose radiation therapy and concomitant fluorouracil-cisplatinum. Long-term results in 95 patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 46, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

1998
[Chemoradiotherapy in treatment of cancer of the anal canal].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 1998, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy,

1998
Overexpression of p53 protein and outcome of patients treated with chemoradiation for carcinoma of the anal canal: a report of randomized trial RTOG 87-04. Radiation Therapy Oncology Group.
    Cancer, 1999, Mar-15, Volume: 85, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Combined M

1999
Assessment of long-term quality of life in patients with anal carcinomas treated by radiotherapy with or without chemotherapy.
    British journal of cancer, 1999, Volume: 80, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb

1999
Intra-arterial chemotherapy in locally advanced or recurrent carcinomas of the penis and anal canal: an active treatment modality with curative potential.
    British journal of cancer, 2000, Volume: 83, Issue:12

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Anus Neoplasms; Arteries; Bleo

2000
High-dose radiation therapy and neoadjuvant plus concomitant chemotherapy with 5-fluorouracil and cisplatin in patients with locally advanced squamous-cell anal canal cancer: final results of a phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemoth

2001
Intracavitary afterloading boost in anal canal carcinoma. Results, function and quality of life.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2001, Volume: 177, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachythera

2001
Condyloma. A new epidemic.
    Archives of surgery (Chicago, Ill. : 1960), 1978, Volume: 113, Issue:5

    Topics: Antineoplastic Agents; Anus Neoplasms; Colorado; Condylomata Acuminata; Cryosurgery; Dinitrochlorobe

1978

Other Studies

311 other studies available for fluorouracil and Anal Cancer

ArticleYear
Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2022, Volume: 34, Issue:1

    Topics: Anus Neoplasms; Chemoradiotherapy; Fluorouracil; Humans; Radiotherapy, Intensity-Modulated; Retrospe

2022
Molecular and genomic characterisation of a panel of human anal cancer cell lines.
    Cell death & disease, 2021, 10-18, Volume: 12, Issue:11

    Topics: Animals; Anus Neoplasms; B7-H1 Antigen; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor;

2021
Current treatment and future directions in the management of anal cancer.
    CA: a cancer journal for clinicians, 2022, Volume: 72, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2022
Second-line treatment after docetaxel, cisplatin and 5-fluorouracil in metastatic squamous cell carcinomas of the anus. Pooled analysis of prospective Epitopes-HPV01 and Epitopes-HPV02 studies.
    European journal of cancer (Oxford, England : 1990), 2022, Volume: 162

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2022
Long-term survival after treatment for primary anal cancer- results from the Swedish national ANCA cohort study.
    Acta oncologica (Stockholm, Sweden), 2022, Volume: 61, Issue:4

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplas

2022
Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution.
    The oncologist, 2022, 02-03, Volume: 27, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2022
Treatment results for patients with squamous-cell carcinoma of the anus, a single institution retrospective analysis.
    Radiation oncology (London, England), 2022, Apr-20, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neo

2022
New approaches in palliative systemic therapy of anal squamous cell carcinoma.
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2022,Spring, Volume: 35, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2022
Efficacy and tolerance of cetuximab in combination with 5 FU plus irinotecan based chemotherapy in metastatic squamous cell anal carcinoma.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2023, Volume: 55, Issue:3

    Topics: Anal Canal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemo

2023
Concurrent Chemo-radiotherapy in Anal Squamous Cell Carcinoma: A Retrospective Review of a Tertiary Centre Experience.
    Journal of gastrointestinal cancer, 2023, Volume: 54, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2023
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis of RTOG 9811 and RTOG 0529.
    American journal of clinical oncology, 2022, 12-01, Volume: 45, Issue:12

    Topics: Anus Neoplasms; Fluorouracil; Humans; Prospective Studies; Radiotherapy, Conformal; Radiotherapy, In

2022
Evaluation of dosimetric predictors of toxicity after IMRT with concurrent chemotherapy for anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Dermatitis; Diarr

2023
Evaluation of dosimetric predictors of toxicity after IMRT with concurrent chemotherapy for anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Dermatitis; Diarr

2023
Evaluation of dosimetric predictors of toxicity after IMRT with concurrent chemotherapy for anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Dermatitis; Diarr

2023
Evaluation of dosimetric predictors of toxicity after IMRT with concurrent chemotherapy for anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 178

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Dermatitis; Diarr

2023
Definitive chemoradiation in nonmetastatic squamous cell carcinoma anal canal: A single-institution experience.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:Supplement

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2022
Definitive chemoradiation in nonmetastatic squamous cell carcinoma anal canal: A single-institution experience.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:Supplement

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2022
Definitive chemoradiation in nonmetastatic squamous cell carcinoma anal canal: A single-institution experience.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:Supplement

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2022
Definitive chemoradiation in nonmetastatic squamous cell carcinoma anal canal: A single-institution experience.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:Supplement

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2022
[A Case of Long-Term Survival with S-1/Cisplatin for Liver Hilum Lymph Node Metastasis of Anal Canal Squamous Cell Carcinoma after Chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2022, Volume: 49, Issue:13

    Topics: Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamou

2022
Treatment, outcome, and prognostic factors in non-metastatic anal cancer: The French nationwide cohort study FFCD-ANABASE.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 183

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2023
Revisiting the Radical Radiotherapy-Radiochemotherapy Results in Anal Canal Cancers: (TROD Gastrointestinal Group Study 02-005).
    Clinical colorectal cancer, 2023, Volume: 22, Issue:3

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Disea

2023
Capecitabine/Mitomycin versus 5-Fluorouracil/Mitomycin in Combination with Simultaneous Integrated Boost Intensity-Modulated Radiation Therapy for Anal Cancer.
    Current oncology (Toronto, Ont.), 2023, 09-18, Volume: 30, Issue:9

    Topics: Anus Neoplasms; Capecitabine; Cohort Studies; Fluorouracil; Humans; Mitomycin; Prospective Studies;

2023
Mitomycin and 5-fluorouracil for second-line treatment of metastatic squamous cell carcinomas of the anal canal.
    Cancer medicine, 2019, Volume: 8, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms;

2019
Outcomes after intensity-modulated compared with 3-dimensional conformal radiotherapy with chemotherapy for squamous cell carcinoma of the anal canal.
    Current oncology (Toronto, Ont.), 2019, Volume: 26, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2019
Sweet syndrome and erythema nodosum in a case of anal canal cancer during concomitant radiochemotherapy.
    European journal of dermatology : EJD, 2019, Oct-01, Volume: 29, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Erythema Nodosum;

2019
Long-term follow-up experience in anal canal cancer treated with Intensity-Modulated Radiation Therapy: Clinical outcomes, patterns of relapse and predictors of failure.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 144

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2020
Improved treatment outcome and lower skin toxicity with intensity-modulated radiotherapy vs. 3D conventional radiotherapy in anal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; F

2020
Factors Associated With Chemoradiation Therapy Interruption and Noncompletion Among Patients With Squamous Cell Anal Carcinoma.
    JAMA oncology, 2020, 06-01, Volume: 6, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy;

2020
Patient-Reported GI Outcomes in Patients With Anal Cancer Receiving Modern Chemoradiation.
    JCO oncology practice, 2020, Volume: 16, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Fluorouracil; Hum

2020
Feasibility and Outcome of Routine Use of Concurrent Chemoradiation in HIV-positive Patients With Squamous Cell Anal Cancer.
    American journal of clinical oncology, 2020, Volume: 43, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2020
Haematotoxicity in IMRT/VMAT curatively treated anal cancer.
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2020,Summer, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma,

2020
How to Choose the Right Treatment for Patients With Advanced Squamous Cell Carcinoma in the Absence of a Comparative Randomized Clinical Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 11-20, Volume: 38, Issue:33

    Topics: Anus Neoplasms; Carboplatin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Humans; Paclitaxel

2020
Reply to S. Kim et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 11-20, Volume: 38, Issue:33

    Topics: Anus Neoplasms; Carboplatin; Cisplatin; Fluorouracil; Humans; Paclitaxel

2020
Outcomes of Squamous Cell Carcinoma Anal Canal treated with IMRT-VMAT-based Concurrent Chemoradiation: a Single Institutional Experience.
    Journal of gastrointestinal cancer, 2022, Volume: 53, Issue:1

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2022
Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols?
    Diseases of the colon and rectum, 2021, 09-01, Volume: 64, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2021
Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
    Radiation oncology (London, England), 2021, Aug-16, Volume: 16, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chem

2021
Predictors of Radiation Therapy-Related Gastrointestinal Toxicity From Anal Cancer Dose-Painted Intensity Modulated Radiation Therapy: Secondary Analysis of NRG Oncology RTOG 0529.
    International journal of radiation oncology, biology, physics, 2017, 06-01, Volume: 98, Issue:2

    Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Co

2017
PET-CT guided SIB-IMRT combined with concurrent 5-FU/MMC for the treatment of anal cancer.
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2017
Chemotherapy-induced Takotsubo cardiomyopathy, a case report and review of the literature.
    BMC cancer, 2017, 06-02, Volume: 17, Issue:1

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Recurr

2017
Multimodal Therapy of Squamous Cell Carcinoma of the Anus With Distant Metastasis: A Single-Institution Experience.
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone

2017
Chemotherapy, "Lighting the Fire" or "Releasing the Brakes" in Metastatic Anal Cancer.
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Catheter A

2017
[A Case of Perianal Squamous Cell Carcinoma with Left Inguinal Lymph Node Metastasis That Showed a Complete Response More Than Five Years after Chemotherapy and Concomitant Proton Beam Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2017, Volume: 44, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Che

2017
Early closure of fistula using neo-adjuvant intra-arterial chemotherapy in locally advanced anal cancer.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Chemoradioth

2017
Lung transplantation for mitomycin-induced pulmonary veno-occlusive disease.
    Presse medicale (Paris, France : 1983), 2017, Volume: 46, Issue:12 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Female; Fluorouracil; Humans; Hypert

2017
The prognostic role of hemoglobin levels in patients undergoing concurrent chemo-radiation for anal cancer.
    Radiation oncology (London, England), 2018, May-02, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Biom

2018
Tolerability of ADXS11-001 Lm-LLO Listeria-Based Immunotherapy With Mitomycin, Fluorouracil, and Radiation for Anal Cancer.
    International journal of radiation oncology, biology, physics, 2018, 04-01, Volume: 100, Issue:5

    Topics: Adult; Aged; Anus Neoplasms; Bacterial Vaccines; Chemoradiotherapy; Female; Fluorouracil; Humans; Im

2018
Toxicity, Tolerability, and Compliance of Concurrent Capecitabine or 5-Fluorouracil in Radical Management of Anal Cancer With Single-dose Mitomycin-C and Intensity Modulated Radiation Therapy: Evaluation of a National Cohort.
    International journal of radiation oncology, biology, physics, 2018, 08-01, Volume: 101, Issue:5

    Topics: Adenocarcinoma; Aged; Anus Neoplasms; Capecitabine; Carcinoma, Squamous Cell; Chemoradiotherapy; Coh

2018
Building evidence-based treatment recommendations for advanced anal cancer: the time is now.
    The Lancet. Oncology, 2018, Volume: 19, Issue:8

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Epitopes; Fluorouracil; Humans; Neop

2018
Treatment Effects Can Mimic Recurrent Extramammary Paget Disease in Perianal Skin.
    The American journal of surgical pathology, 2018, Volume: 42, Issue:11

    Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Anus Neoplasms; Biomarkers, Tumor; Biops

2018
Intensity-modulated Radiotherapy for Anal Cancer: Dose-Volume Relationship of Acute Gastrointestinal Toxicity and Disease Outcomes.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2018, Volume: 30, Issue:10

    Topics: Abdominal Cavity; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; An

2018
Comparing simultaneous integrated boost vs sequential boost in anal cancer patients: results of a retrospective observational study.
    Radiation oncology (London, England), 2018, Sep-10, Volume: 13, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; Chemoradiotherap

2018
Real world survival data of a rare malignancy: Anal cancer results in HIV negative patients from Turkey.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2018
FOLFCIS Treatment and Genomic Correlates of Response in Advanced Anal Squamous Cell Cancer.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Biom

2019
Intensity-modulated radiotherapy improves survival and reduces treatment time in squamous cell carcinoma of the anus: A National Cancer Data Base study.
    Cancer, 2018, 11-15, Volume: 124, Issue:22

    Topics: Aged; Aged, 80 and over; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Databases, Fac

2018
Chemoradiotherapy with and without deep regional hyperthermia for squamous cell carcinoma of the anus.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019, Volume: 195, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Brachytherapy; Carcinoma, Squamous Cell; Chemoradiot

2019
Anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease, successfully treated with modified FOLFOX6: a case report.
    BMC cancer, 2018, Nov-20, Volume: 18, Issue:1

    Topics: Adenocarcinoma; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Ca

2018
Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects.
    Tumori, 2019, Volume: 105, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2019
[Outcomes of Anal Squamous Cell Carcinoma Treated with Chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2018
[A Case of Colostomy-Free and Long-Term Survival with 5-FU/CDDP for Local Recurrence of Anal Cancer after Chemoradiation Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Colostomy; Female

2019
Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study.
    International journal of radiation oncology, biology, physics, 2019, 09-01, Volume: 105, Issue:1

    Topics: Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamou

2019
Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication.
    Annali italiani di chirurgia, 2019, Jun-26, Volume: 8

    Topics: Aged; Anaphylaxis; Anus Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Colon, Si

2019
One step towards standardised management of anal dysplasia.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aminoquinolines; Anus Neoplasms; Electrocoagulation; Fluorouracil; Homosexuality, Male; Humans; Imiq

2013
RTOG 0529: Intensity modulated radiation therapy and anal cancer, a step in the right direction?
    International journal of radiation oncology, biology, physics, 2013, May-01, Volume: 86, Issue:1

    Topics: Anal Canal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; C

2013
Elective inguinal node irradiation in early-stage T2N0 anal cancer: prognostic impact on locoregional control.
    International journal of radiation oncology, biology, physics, 2013, Sep-01, Volume: 87, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2013
Epidermal growth factor receptor expression as prognostic marker in patients with anal carcinoma treated with concurrent chemoradiation therapy.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiother

2013
Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2013
Anal carcinoma: surgery does not influence prognosis when performed prior to concurrent radiochemotherapy.
    Anticancer research, 2013, Volume: 33, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb

2013
DCF (docetaxel, cisplatin and 5-fluorouracil) chemotherapy is a promising treatment for recurrent advanced squamous cell anal carcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Disease-Free

2013
Impact of chemotherapy on normal tissue complication probability models of acute hematologic toxicity in patients receiving pelvic intensity modulated radiation therapy.
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Aged; Antineoplastic Agents; Anus Neoplasms; Bone Marrow; Chemoradiotherapy; Cisplatin; Drug Adminis

2013
Combination chemotherapy for metastatic extramammary Paget disease.
    The British journal of dermatology, 2014, Volume: 170, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Neopla

2014
Intensity-modulated Radiation Therapy for Anal Cancer: Results From a Multi-Institutional Retrospective Cohort Study.
    American journal of clinical oncology, 2016, Volume: 39, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape

2016
Results of age-dependent anal canal cancer treatment: a single centre retrospective study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2014, Volume: 46, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Ne

2014
Long-term effects of chemoradiotherapy for anal cancer in patients with HIV infection: oncological outcomes, immunological status, and the clinical course of the HIV disease.
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms;

2014
KRAS, BRAF and PIK3CA status in squamous cell anal carcinoma (SCAC).
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Aged; Antineoplastic Agents; Anus Neoplasms; Axons; Carcinoma, Squamous Cell; Class I Phosphatidylin

2014
External beam radiotherapy ± chemotherapy in the treatment of anal canal cancer: a single-institute long-term experience on 100 patients.
    Cancer investigation, 2014, Volume: 32, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Cisplatin; Combined Modality Therapy; Female; Fluoro

2014
Inguinal lymph node recurrence in the untreated groin of patients with anal carcinoma.
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Anus Neoplasms; Combined Modality Therapy; Fe

2014
Human papillomavirus DNA load and p16INK4a expression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy.
    International journal of cancer, 2015, Jan-15, Volume: 136, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Biomarkers, Tumor; Carcinoma, Squamo

2015
Chemoradiation with capecitabine and mitomycin-C for stage I-III anal squamous cell carcinoma.
    Radiation oncology (London, England), 2014, May-29, Volume: 9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus

2014
Fat composition changes in bone marrow during chemotherapy and radiation therapy.
    International journal of radiation oncology, biology, physics, 2014, Sep-01, Volume: 90, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Co

2014
Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option.
    British journal of cancer, 2014, Oct-28, Volume: 111, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus

2014
The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal.
    Oncotarget, 2014, Nov-30, Volume: 5, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carb

2014
Anal carcinoma - Survival and recurrence in a large cohort of patients treated according to Nordic guidelines.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Cisplatin;

2014
[Management of locally advanced anal canal carcinoma with modulated arctherapy and concurrent chemotherapy].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2015, Volume: 19, Issue:2

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2015
Review of anal cancer patients at the Ottawa hospital.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neo

2015
Concomitant chemoradiotherapy with Cisplatin plus 5-Fluorouracil for anal squamous cell carcinoma.
    Journal of gastrointestinal cancer, 2015, Volume: 46, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachytherapy; Carcinom

2015
Intensity-Modulated Radiotherapy (IMRT) vs Helical Tomotherapy (HT) in Concurrent Chemoradiotherapy (CRT) for Patients with Anal Canal Carcinoma (ACC): an analysis of dose distribution and toxicities.
    Radiation oncology (London, England), 2015, Apr-17, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chem

2015
Perianal infection of highly oncogenic human papilloma virus: how to prevent from cancer? Case report.
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2015, Volume: 68, Issue:2

    Topics: Anal Canal; Anus Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hemorrhoidectomy; He

2015
Chemoradiation for High-grade Neuroendocrine Carcinoma of the Rectum and Anal Canal.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Camptotheci

2017
French multicentre clinical evaluation of helical TomoTherapy for anal cancer in a cohort of 64 consecutive patients.
    Radiation oncology (London, England), 2015, Aug-14, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2015
Evaluation of a 36 Gy elective node irradiation dose in anal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2015
Chemoradiotherapy for squamous cell carcinoma of the anal canal: Comparison of one versus two cycles mitomycin-C.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2015
Implementing Intensity-modulated Radiotherapy with Simultaneous Integrated Boost for Anal Cancer: 3 Year Outcomes at Two Sydney Institutions.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2015, Volume: 27, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Australia; Carcinoma, S

2015
Intensified intensity-modulated radiotherapy in anal cancer with prevalent HPV p16 positivity.
    World journal of gastroenterology, 2015, Oct-07, Volume: 21, Issue:37

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; Cyclin-

2015
Prognostic Relevance of HPV Infection and p16 Overexpression in Squamous Cell Anal Cancer.
    International journal of radiation oncology, biology, physics, 2015, Nov-15, Volume: 93, Issue:4

    Topics: Adult; Age Factors; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Anus

2015
[Results of complex treatment of patients with squamous cell carcinoma of the anal canal using advanced radiotherapy technologies].
    Voprosy onkologii, 2015, Volume: 61, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2015
[Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2016, Volume: 113, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Che

2016
Irradiation of FDG-PET-Defined Active Bone Marrow Subregions and Acute Hematologic Toxicity in Anal Cancer Patients Undergoing Chemoradiation.
    International journal of radiation oncology, biology, physics, 2016, Mar-15, Volume: 94, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Anus Neoplasms; Bone Marrow; Chemoradiotherapy; Cohort Studies;

2016
Dosimetric predictors of acute hematologic toxicity during concurrent intensity-modulated radiotherapy and chemotherapy for anal cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2017, Volume: 19, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus

2017
Rapid Extracorporeal Membrane Oxygenation Overcomes Fulminant Myocarditis Induced by 5‑Fluorouracil.
    Texas Heart Institute journal, 2016, Volume: 43, Issue:2

    Topics: Acute Disease; Anus Neoplasms; Carcinoma, Squamous Cell; Coronary Angiography; Electrocardiography;

2016
Metabolic tumour volume of anal carcinoma on (18)FDG PET/CT before combined radiochemotherapy is the only independant determinant of recurrence free survival.
    European journal of radiology, 2016, Volume: 85, Issue:8

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe

2016
Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy.
    Oncotarget, 2016, 08-16, Volume: 7, Issue:33

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Caspase 8;

2016
Successful Delivery in a 39-Year-Old Patient with Anal Cancer after Fertility-Preserving Surgery Followed by Primary Chemoradiation and Low Anti-Mullerian Hormone Level.
    Oncology, 2016, Volume: 91, Issue:5

    Topics: Adult; Anti-Mullerian Hormone; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carci

2016
Early-Onset 5-Fluorouracil Toxicity in a Patient Negative for Dihydropyrimidine Dehydrogenase Mutations: The Clinical Course of Reversal with Uridine Triacetate.
    Pharmacotherapy, 2016, Volume: 36, Issue:11

    Topics: Acetates; Aged; Antidotes; Antimetabolites, Antineoplastic; Anus Neoplasms; Dihydrouracil Dehydrogen

2016
Lumbar-sacral bone marrow dose modeling for acute hematological toxicity in anal cancer patients treated with concurrent chemo-radiation.
    Medical oncology (Northwood, London, England), 2016, Volume: 33, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Marrow; Chemoradio

2016
The successful treatment of 5-fluorouracil (5-FU) overdose in a patient with malignancy and HIV/AIDS with uridine triacetate.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:5

    Topics: Acetates; Antimetabolites, Antineoplastic; Anus Neoplasms; Depression; Drug Overdose; Emergency Medi

2017
Cetuximab chemoradiotherapy in HIV-associated anal cancer.
    The Lancet. Oncology, 2017, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms

2017
Hematologic Nadirs During Chemoradiation for Anal Cancer: Temporal Characterization and Dosimetric Predictors.
    International journal of radiation oncology, biology, physics, 2017, 02-01, Volume: 97, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Marrow;

2017
Anal cancer: the end of the road for neoadjuvant chemoradiotherapy?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-01, Volume: 26, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy, Adjuvant; Cisplatin; F

2008
US intergroup anal carcinoma trial: tumor diameter predicts for colostomy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-01, Volume: 27, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Colostomy; Combine

2009
Outcomes of chemoradiotherapy with 5-Fluorouracil and mitomycin C for anal cancer in immunocompetent versus immunodeficient patients.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2009
Anal cancer chemoirradiation with curative intent - a single institution experience.
    Neoplasma, 2009, Volume: 56, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2009
Radiotherapy for epidermoid carcinoma of the anus: thirty years' experience.
    International journal of radiation oncology, biology, physics, 2009, Oct-01, Volume: 75, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

2009
Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Biomarkers, Tumor; Carci

2010
Treatment options in metastatic squamous cell carcinoma of the anal canal.
    Current treatment options in oncology, 2008, Volume: 9, Issue:4-6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carboplatin;

2008
HIV and anal cancer outcomes: a single institution's experience.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:5

    Topics: Antineoplastic Agents; Anus Neoplasms; Capecitabine; Carcinoma, Squamous Cell; Chemotherapy, Adjuvan

2009
A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 93, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb

2009
Concurrent chemoradiotherapy with 5-fluorouracil and mitomycin C for invasive anal carcinoma in human immunodeficiency virus-positive patients receiving highly active antiretroviral therapy.
    International journal of radiation oncology, biology, physics, 2010, Volume: 76, Issue:5

    Topics: Adult; Aged; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy

2010
Anal cancer: one step forward--two steps sideways!
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:16

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Clinical T

2009
Successful treatment of a large Buschke-Lowenstein tumour with chemo-radiotherapy.
    International journal of STD & AIDS, 2009, Volume: 20, Issue:10

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Anus Neoplasms; Cisplatin; Combined Modality

2009
Commentary: Anal cancer - the benefits of evidence-based treatment.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2009, Volume: 11, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemotherapy, Adjuvant; Cisplatin; D

2009
[A case of anal canal carcinoma with systemic lymph node metastases successfully treated by bevacizumab+mFOLFOX6 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Anal Canal; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anti

2009
Case report of long term survivor of metastatic cloacogenic carcinoma of the anal canal with chemotherapy.
    The Gulf journal of oncology, 2007, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemothera

2007
Squamous cell carcinoma of the anal canal: patterns and predictors of failure and implications for intensity-modulated radiation treatment planning.
    International journal of radiation oncology, biology, physics, 2010, Nov-15, Volume: 78, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2010
Anal cancer with cerebral metastasis: a case report.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:1

    Topics: Antineoplastic Agents; Anus Neoplasms; Brain Neoplasms; Capecitabine; Carcinoma, Squamous Cell; Comb

2011
Chemo-radiation with or without mandatory split in anal carcinoma: experiences of two institutions and review of the literature.
    Radiation oncology (London, England), 2010, May-13, Volume: 5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2010
Quality of life and tumor control after short split-course chemoradiation for anal canal carcinoma.
    Radiation oncology (London, England), 2010, May-23, Volume: 5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2010
High-grade acute organ toxicity as a positive prognostic factor in primary radiochemotherapy for anal carcinoma.
    International journal of radiation oncology, biology, physics, 2011, Apr-01, Volume: 79, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

2011
Topical 5-fluorouracil treatment of anal intraepithelial neoplasia in human immunodeficiency virus-positive men.
    The British journal of dermatology, 2010, Volume: 163, Issue:6

    Topics: Administration, Topical; Adult; Aged; AIDS-Related Opportunistic Infections; Antimetabolites, Antine

2010
Topical 5-fluorouracil treatment of anal intraepithelial neoplasia in human immunodeficiency virus-positive men.
    The British journal of dermatology, 2010, Volume: 163, Issue:6

    Topics: Administration, Topical; Adult; Aged; AIDS-Related Opportunistic Infections; Antimetabolites, Antine

2010
Topical 5-fluorouracil treatment of anal intraepithelial neoplasia in human immunodeficiency virus-positive men.
    The British journal of dermatology, 2010, Volume: 163, Issue:6

    Topics: Administration, Topical; Adult; Aged; AIDS-Related Opportunistic Infections; Antimetabolites, Antine

2010
Topical 5-fluorouracil treatment of anal intraepithelial neoplasia in human immunodeficiency virus-positive men.
    The British journal of dermatology, 2010, Volume: 163, Issue:6

    Topics: Administration, Topical; Adult; Aged; AIDS-Related Opportunistic Infections; Antimetabolites, Antine

2010
Squamous cell carcinoma of the anal margin: the university of Florida experience.
    American journal of clinical oncology, 2011, Volume: 34, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2011
Efficacy and toxicity of chemoradiation in the treatment of HIV-associated anal cancer.
    Clinical colorectal cancer, 2010, Volume: 9, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
Impact of overall treatment time on survival and local control in patients with anal cancer: a pooled data analysis of Radiation Therapy Oncology Group trials 87-04 and 98-11.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Antineoplastic Agents; Anus Neoplasms; Cisplatin; Clinical Trials as Topic; Combined Modality Therap

2010
[mFOLFOX6 for treatment of anal canal cancer with disseminated carcinomatosis of bone marrow--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Marrow Ne

2010
Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squam

2012
[Three cases of radiotherapy combined with S-1 and mitomycin C for anal canal squamous cell carcinomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:13

    Topics: Administration, Oral; Aged; Anal Canal; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic

2010
Concurrent chemoradiotherapy with 5-fluorouracil and mitomycin C for anal carcinoma: are there differences between HIV-positive and HIV-negative patients in the era of highly active antiretroviral therapy?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 98, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active;

2011
[Four cases of anal squamous cell carcinoma treated by chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemoth

2010
[A case of squamous cell carcinoma of the anal cancer with associated human immunodeficiency virus].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic

2010
Is neoadjuvant chemotherapy prior to radio-chemotherapy beneficial in T4 anal carcinoma?
    Journal of surgical oncology, 2011, Jul-01, Volume: 104, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2011
Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal.
    Cancer, 2011, Aug-01, Volume: 117, Issue:15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2011
Quality of life outcomes in patients with anal cancer after combined radiochemotherapy.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anus Neoplasms; Chemotherapy, Adjuvant;

2011
Chemoradiotherapy for anal cancer in HIV patients causes prolonged CD4 cell count suppression.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; CD4 Lymph

2012
Node-negative T1-T2 anal cancer: radiotherapy alone or concomitant chemoradiotherapy?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Combined Mo

2012
Twenty-five-year experience with radical chemoradiation for anal cancer.
    International journal of radiation oncology, biology, physics, 2012, Jun-01, Volume: 83, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2012
Primary Signet Ring Cell Anal Adenocarcinoma.
    Journal of gastrointestinal cancer, 2012, Volume: 43 Suppl 1

    Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Signet Ring Cell; Col

2012
Endobronchial metastases of anal canal carcinoma.
    Archivos de bronconeumologia, 2012, Volume: 48, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bronchial Neoplasms; Bronchopneumoni

2012
Concurrent chemotherapy and intensity-modulated radiation therapy for anal carcinoma--clinical outcomes in a large National Cancer Institute-designated integrated cancer centre network.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2012, Volume: 24, Issue:6

    Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Proto

2012
Single-agent paclitaxel in advanced anal cancer after failure of cisplatin and 5-fluorouracil chemotherapy.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Adult; Antineoplastic Agents; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Disease Progressi

2011
[Preoperative chemoradiation (XELOX/RT) therapy for anal canal adenocarcinoma with the metastasis to inguinal lymph node].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Adenocarcinoma; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecita

2011
Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patients.
    British journal of cancer, 2012, Feb-14, Volume: 106, Issue:4

    Topics: Aged; Anus Neoplasms; Cadherins; Carcinoma, Squamous Cell; Combined Modality Therapy; Desmocollins;

2012
Development of a standardized method for contouring the lumbosacral plexus: a preliminary dosimetric analysis of this organ at risk among 15 patients treated with intensity-modulated radiotherapy for lower gastrointestinal cancers and the incidence of rad
    International journal of radiation oncology, biology, physics, 2012, Oct-01, Volume: 84, Issue:2

    Topics: Anatomic Landmarks; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Fluorouracil; Hu

2012
Normal tissue complication probability modeling of acute hematologic toxicity in patients treated with intensity-modulated radiation therapy for squamous cell carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Anus Neoplasms; Bone Marrow; Capeci

2012
Chemoradiotherapy of anal carcinoma: survival and recurrence in an unselected national cohort.
    International journal of radiation oncology, biology, physics, 2012, Jun-01, Volume: 83, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Ne

2012
Role of positron emission tomography-computed tomography in the management of anal cancer.
    International journal of radiation oncology, biology, physics, 2012, Sep-01, Volume: 84, Issue:1

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma,

2012
Treatment of carcinoma of the anal canal at Groote Schuur Hospital.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2012, May-23, Volume: 102, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neo

2012
Prospective study of functional bone marrow-sparing intensity modulated radiation therapy with concurrent chemotherapy for pelvic malignancies.
    International journal of radiation oncology, biology, physics, 2013, Feb-01, Volume: 85, Issue:2

    Topics: Adipose Tissue; Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Marrow;

2013
High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy.
    Radiation oncology (London, England), 2012, Jun-14, Volume: 7

    Topics: Antineoplastic Agents; Anus Neoplasms; Chemoradiotherapy; Female; Fluorouracil; Humans; Immunohistoc

2012
Early clinical outcomes of anal squamous cell carcinoma treated with concurrent chemoradiotherapy with 5-Fluorouracil plus mitomycin C in Japanese patients: experience at a single institution.
    Japanese journal of clinical oncology, 2012, Volume: 42, Issue:9

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C

2012
Self-assessment quiz: answers, critiques, and references.
    Diseases of the colon and rectum, 2012, Volume: 55, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcino

2012
Capecitabine-induced chest pain relieved by diltiazem.
    The American journal of cardiology, 2012, Dec-01, Volume: 110, Issue:11

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Anus Neoplasms; Calcium Channel Blockers; Cap

2012
FOLFIRI regimen: an effective second-line chemotherapy after failure of etoposide-platinum combination in patients with neuroendocrine carcinomas grade 3.
    Endocrine-related cancer, 2012, Volume: 19, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Camptothecin; Carcinoma

2012
Does gap-free intensity modulated chemoradiation therapy provide a greater clinical benefit than 3D conformal chemoradiation in patients with anal cancer?
    Radiation oncology (London, England), 2012, Nov-29, Volume: 7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape

2012
Ten-year results of chemoradiation for anal cancer: focus on late morbidity.
    International journal of radiation oncology, biology, physics, 1996, Jan-01, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb

1996
Successful chemoradiotherapy for anal cancer despite previous radical radiotherapy for gynaecological malignancy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2002, Volume: 14, Issue:4

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Endometrial Neopla

2002
Chemoradiation for adenocarcinoma of the anus.
    International journal of radiation oncology, biology, physics, 2003, Mar-01, Volume: 55, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Anus Neoplasms; Carcinoma, Sq

2003
Cisplatin-based combined modality therapy for anal carcinoma: a wider therapeutic index.
    Cancer, 2003, Mar-01, Volume: 97, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2003
Concurrent chemoradiotherapy for squamous cell carcinoma of the anus using a shrinking field radiotherapy technique without a boost.
    British journal of cancer, 2003, May-06, Volume: 88, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Dise

2003
Anal canal cancer treatment: practical limitations of routine prescription of concurrent chemotherapy and radiotherapy.
    British journal of cancer, 2003, Dec-01, Volume: 89, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2003
Blue fingers.
    Internal medicine journal, 2003, Volume: 33, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fingers; Fl

2003
[Radiotherapy of carcinomas of the anal canal. Tenon Hospital experience].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2003, Volume: 7 Suppl 1

    Topics: Aged; Anal Canal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Ch

2003
Recent clinical trials summary.
    Surgical oncology clinics of North America, 2004, Volume: 13, Issue:2

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2004
Treatment of T3 and T4 anal carcinoma with combined chemoradiation and interstitial 192Ir implantation: a 10-year experience.
    Brachytherapy, 2004, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Anus Neoplasms; Brachytherapy; Female;

2004
Bilateral leg amputation following chemoradiation for squamous carcinoma of the anus.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 73, Issue:1

    Topics: Aged; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinom

2004
Radiochemotherapy in the conservative treatment of anal canal carcinoma: retrospective analysis of results and radiation dose effectiveness.
    International journal of radiation oncology, biology, physics, 2005, Mar-15, Volume: 61, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2005
[Prognosis of epidermoid anal carcinoma regression after conservative treatment].
    Voprosy onkologii, 2004, Volume: 50, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2004
Anal carcinomas in HIV-positive patients: high-dose chemoradiotherapy is feasible in the era of highly active antiretroviral therapy.
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:6

    Topics: Adult; Anti-Retroviral Agents; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Anus Ne

2005
Tumor site predicts outcome after radiochemotherapy in squamous-cell carcinoma of the anal region: long-term results of 101 patients.
    Diseases of the colon and rectum, 2005, Volume: 48, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2005
Buschke-Löwenstein tumor in childhood: a case report.
    Journal of pediatric surgery, 2005, Volume: 40, Issue:9

    Topics: Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Verrucous; Child; Condylomata Acuminata;

2005
Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome.
    International journal of radiation oncology, biology, physics, 2005, Oct-01, Volume: 63, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Anus Neoplasms; Carcinoma, Squamous Cell; Fem

2005
Basaloid squamous carcinoma of the anal canal with an adenoid cystic pattern: histologic and immunohistochemical reappraisal of an unusual variant.
    The American journal of surgical pathology, 2005, Volume: 29, Issue:12

    Topics: Anal Canal; Antibiotics, Antineoplastic; Antigens, CD20; Antimetabolites, Antineoplastic; Antineopla

2005
Combined treatment of basaloid anal carcinoma using cisplatin, 5-fluorouracil and resection of hepatic metastasis.
    Techniques in coloproctology, 2005, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Biopsy, Needle; Carcinoma, Squamous

2005
[Chemoradiotherapy and anal canal cancer].
    Bulletin du cancer, 2005, Volume: 92, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Clinical Trials, Phase III as Topic;

2005
Intermediate dose 5-fluorouracil-induced encephalopathy.
    Japanese journal of clinical oncology, 2006, Volume: 36, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasm

2006
The bottom line: outcomes after conservation treatment in anal cancer.
    Australasian radiology, 2006, Volume: 50, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma,

2006
[Mucinous adenocarcinoma on chronic perianal fistula treated by neoadjuvant chemoradiotherapy and laparoscopy-assisted abdominoperineal amputation].
    Cirugia espanola, 2006, Volume: 79, Issue:3

    Topics: Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Anus Neoplasms; Chemotherapy, Adjuvant; C

2006
Reversible findings of restricted diffusion in 5-fluorouracil neurotoxicity.
    Australasian radiology, 2006, Volume: 50, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Corpus Callosum; F

2006
Combined modality therapy for HIV-infected patients with squamous cell carcinoma of the anus: outcomes and toxicities.
    International journal of radiation oncology, biology, physics, 2006, Sep-01, Volume: 66, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cis

2006
Chemoradiotherapy of anal cancer is feasible in elderly patients: treatment results of mitomycin-5-FU combined with radiotherapy at Helsinki University Central Hospital 1992-2003.
    Acta oncologica (Stockholm, Sweden), 2006, Volume: 45, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Fema

2006
Chemoradiotherapy in patients with anal cancer: impact of length of unplanned treatment interruption on outcome.
    Acta oncologica (Stockholm, Sweden), 2006, Volume: 45, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; C

2006
HIV-associated anal squamous cell cancer: an otherwise preventable disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Anus Neoplasm

2006
[Epidermoid carcinomas of anal canal treated with radiation therapy and concomitant chemotherapy (5-fluorouracil and cisplatin)].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2006, Volume: 10, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Antineoplastic Combined

2006
Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2006, Volume: 4, Issue:6

    Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinom

2006
Conformal therapy improves the therapeutic index of patients with anal canal cancer treated with combined chemotherapy and external beam radiotherapy.
    International journal of radiation oncology, biology, physics, 2007, Apr-01, Volume: 67, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Combined Modality T

2007
Higher radiation dose with a shorter treatment duration improves outcome for locally advanced carcinoma of anal canal.
    World journal of gastroenterology, 2007, Feb-14, Volume: 13, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Thera

2007
Anus-preservation treatment for anal cancer: retrospective analysis at a single institution.
    Journal of surgical oncology, 2007, Oct-01, Volume: 96, Issue:5

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Pro

2007
Involved-field, low-dose chemoradiotherapy for early-stage anal carcinoma.
    International journal of radiation oncology, biology, physics, 2008, Feb-01, Volume: 70, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Thera

2008
Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-10, Volume: 25, Issue:29

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2007
Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy.
    International journal of radiation oncology, biology, physics, 2008, Apr-01, Volume: 70, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplas

2008
Pelvic phased-array MR imaging of anal carcinoma before and after chemoradiation.
    The British journal of radiology, 2008, Volume: 81, Issue:962

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Anus N

2008
Infusion of 5-fluorouracil into the hypogastric artery for massive anal carcinoma.
    American journal of surgery, 1967, Volume: 113, Issue:5

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Fluorouracil; Humans; Infusions, Parenteral;

1967
Preoperative chemotherapy and radiation therapy in the management of anal epidermoid carcinoma.
    Cancer, 1983, Feb-01, Volume: 51, Issue:3

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorourac

1983
Definitive nonsurgical therapy of epithelial malignancies of the anal canal. A report of 12 cases.
    Cancer, 1983, Apr-15, Volume: 51, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Anus Neoplasms; Brachytherapy; Carcinoma, Squamous Cell; Drug Th

1983
Carcinoma of the anal canal--radiation or radiation plus chemotherapy?
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:9

    Topics: Anus Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Mitomycin; Mitomycins; Radiotherapy

1983
Results and toxicity of the treatment of anal canal carcinoma by radiation therapy or radiation therapy and chemotherapy.
    Cancer, 1984, Nov-15, Volume: 54, Issue:10

    Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Car

1984
Regression of pulmonary metastases from cloacogenic carcinoma after cis-platinum/5-fluorouracil treatment.
    Journal of clinical gastroenterology, 1984, Volume: 6, Issue:3

    Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Transit

1984
Combined radical radiation therapy and chemotherapy for primary squamous cell carcinoma of the anal canal.
    Cancer treatment reports, 1982, Volume: 66, Issue:3

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorourac

1982
Definitive treatment of anal-canal carcinoma by means of radiation therapy and chemotherapy.
    Diseases of the colon and rectum, 1982, Volume: 25, Issue:7

    Topics: Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Hum

1982
Combined preoperative radiation and chemotherapy for squamous cell carcinoma of the anal canal.
    Cancer, 1983, May-15, Volume: 51, Issue:10

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Middle Ag

1983
Radiation therapy and chemotherapy in the treatment of primary anal canal carcinoma.
    Comprehensive therapy, 1983, Volume: 9, Issue:1

    Topics: Anus Neoplasms; Carcinoma; Female; Fluorouracil; Humans; Male; Mitomycins

1983
Multimodality approach to surgical management of locally advanced epidermoid carcinoma of the anorectum.
    Cancer, 1981, Jun-15, Volume: 47, Issue:12

    Topics: Aged; Anus Neoplasms; Brachytherapy; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lymphat

1981
Response of metastatic cloacogenic carcinoma to treatment with semustine.
    Cancer, 1981, Dec-15, Volume: 48, Issue:12

    Topics: Anus Neoplasms; Carcinoma, Transitional Cell; Drug Administration Schedule; Female; Fluorouracil; Hu

1981
Treatment of carcinoma of the rectum and squamous carcinoma of the anus by combination chemotherapy, radiotherapy and operation.
    Surgery, gynecology & obstetrics, 1980, Volume: 151, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans;

1980
Combined treatment of squamous cell carcinoma of the anal canal: radical radiation therapy with 5-fluorouracil and mitomycin-C, a preliminary report.
    Diseases of the colon and rectum, 1980, Volume: 23, Issue:6

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorourac

1980
Treatment of invasive squamous cell carcinoma complicating anal Buschke-Löwenstein tumor: a case history.
    Cutis, 1995, Volume: 55, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Diseases; Anus Neoplasms; Carcinoma, Squamous C

1995
Isolated pelvic perfusion for unresectable cancer using a balloon occlusion technique.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcino

1993
The influence of age on the management of anal cancer.
    Hepato-gastroenterology, 1995, Volume: 42, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamo

1995
Colo-rectal carcinoma in a tropical African population: an overview report.
    East African medical journal, 1994, Volume: 71, Issue:10

    Topics: Adenocarcinoma; Administration, Rectal; Adolescent; Adult; Aged; Anus Neoplasms; Ascites; Colonic Ne

1994
Carcinoma of the anal canal.
    American journal of clinical oncology, 1995, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy;

1995
[A case of fistula-cancer response to arterial chemoembolization].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoembolization, T

1994
Prevention of 5 fluorouracil associated cardiotoxicity.
    Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Female; Fluorouracil; Heart; Humans; Powders; Uterin

1994
[Therapy of anal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therap

1994
Recurrent squamous cell carcinoma of the anal canal. Predictors of initial treatment failure and results of salvage therapy.
    Annals of surgery, 1994, Volume: 220, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Comb

1994
[The prognostic factors following the simultaneous radiochemotherapy of anal canal carcinoma in a multicenter series of 139 patients].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1994, Volume: 170, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1994
Squamous-cell carcinoma of the anus in HIV-positive patients.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anu

1994
[Extended reversible global left ventricular contraction dysfunction with symptomless coronary system as effect of cytostatic therapy with 5-fluorouracil].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1994, Volume: 170, Issue:8

    Topics: Anus Neoplasms; Combined Modality Therapy; Coronary Angiography; Coronary Vasospasm; Diagnosis, Diff

1994
Tolerance of patients with human immunodeficiency virus and anal carcinoma to treatment with combined chemotherapy and radiation therapy.
    Radiology, 1994, Volume: 193, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neop

1994
Cancer of the anal canal: treatment with chemotherapy and low-dose radiation therapy.
    Radiology, 1994, Volume: 191, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Carcinoma,

1994
Epidermoid carcinoma of the anal canal. Results of curative-intent radiation therapy in a series of 270 patients.
    Cancer, 1994, Mar-15, Volume: 73, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neo

1994
Radiation therapy in the conservative treatment of carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachytherapy; Carcinom

1994
Laparoscopic intestinal stomas.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Colonic Diseases; Colostomy;

1994
Carcinoma of the anus treated with primary radiation therapy and chemotherapy.
    Surgery, gynecology & obstetrics, 1993, Volume: 177, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Clinical P

1993
[Radiochemotherapy in anal carcinoma: radiation plus 5-FU with and without long-term cisplatin infusion].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1993, Volume: 169, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Combined Modality Therapy

1993
Cisplatin and 5-fluorouracil as salvage therapy for recurrent metastatic squamous cell carcinoma of the anal canal.
    American journal of clinical oncology, 1993, Volume: 16, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

1993
Epidermoid carcinoma of the anal canal: treatment by combined radiation and chemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 27, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neo

1993
Chemoradiotherapy versus radiotherapy alone for anal cancer: a retrospective comparison.
    International journal of radiation oncology, biology, physics, 1993, Sep-01, Volume: 27, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Fol

1993
Chemoradiotherapy of anal carcinoma: tumour response and acute toxicity.
    Oncology, 1993, Volume: 50, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1993
An alternative treatment of anal squamous cell carcinoma: combined radiotherapy and chemotherapy.
    Journal of surgical oncology, 1993, Volume: 52, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy;

1993
Treatment of relapsing anal carcinoma.
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1993
Results of combined modality therapy for patients with anal cancer (E7283). An Eastern Cooperative Oncology Group study.
    Cancer, 1995, Nov-15, Volume: 76, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb

1995
Management of carcinoma anal canal with combination chemotherapy and concurrent radiotherapy.
    Journal of the Indian Medical Association, 1996, Volume: 94, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C

1996
Epidermoid anal cancer in HIV infected patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Combined M

1996
[Outcome of simultaneous radiochemotherapy of anal carcinoma].
    Zentralblatt fur Chirurgie, 1997, Volume: 122, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma,

1997
Chemotherapy and low-dose radiotherapy in the treatment of HIV-infected patients with carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 1997, Mar-15, Volume: 37, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

1997
Time-dose considerations in the treatment of anal cancer.
    International journal of radiation oncology, biology, physics, 1997, Oct-01, Volume: 39, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Anus Neoplasms; Combine

1997
Low acute toxicity of radiotherapy and radiochemotherapy in patients with cancer of the anal canal and HIV-infection.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Dr

1997
Induction chemotherapy and radiotherapy in loco-regionally advanced epidermoid carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 1998, Jul-01, Volume: 41, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carb

1998
Role of a DT-diaphorase mutation in the response of anal canal carcinoma to radiation, 5-fluorouracil, and mitomycin C.
    International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fluoroura

1998
Treatment of anal carcinoma in the elderly: feasibility and outcome of radical radiotherapy with or without concomitant chemotherapy.
    Cancer, 1999, Jan-01, Volume: 85, Issue:1

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplasti

1999
Failure of oral nitrate and calcium channel blocker therapy to prevent 5-fluorouracil-related myocardial ischemia: a case report.
    Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:2

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Anus Neoplasms; Calcium Channel Blockers; Car

1999
The significance of pretreatment CD4 count on the outcome and treatment tolerance of HIV-positive patients with anal cancer.
    International journal of radiation oncology, biology, physics, 1999, Apr-01, Volume: 44, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; CD4 Lymphocyte Count; Cisplatin; Com

1999
Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 1999, Sep-01, Volume: 45, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1999
[5-fluorouracile and cisplatinum combination chemotherapy for metastatic squamous-cell anal cancer].
    Bulletin du cancer, 1999, Volume: 86, Issue:10

    Topics: Actuarial Analysis; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined

1999
Treatment of HIV-associated invasive anal cancer with combined chemoradiation.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fl

2000
[Initial locoregional chemotherapy in recurrent and locoregional advanced or inoperable stages of pelvic uterine and anorectal cancers].
    Bulletin du cancer, 1995, Volume: 82, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Cisplatin; D

1995
nm23-H1 protein expression in anal canal carcinoma: does it correlate with prognosis?
    Journal of surgical oncology, 2000, Volume: 74, Issue:2

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combin

2000
Spontaneous apparent clinical resolution with histologic persistence of a case of extramammary Paget's disease: response to topical 5-fluorouracil.
    Cutis, 2000, Volume: 66, Issue:6

    Topics: Anus Neoplasms; Dose Fractionation, Radiation; Female; Fluorouracil; Follow-Up Studies; Humans; Neop

2000
Imiquimod and 5% fluorouracil therapy for anal and perianal squamous cell carcinoma in situ in an HIV-1-positive man.
    Archives of dermatology, 2001, Volume: 137, Issue:1

    Topics: Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma in Situ;

2001
Experience with split-course external beam irradiation +/- chemotherapy and integrated Ir-192 high-dose-rate brachytherapy in the treatment of primary carcinomas of the anal canal.
    International journal of radiation oncology, biology, physics, 2001, Mar-15, Volume: 49, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2001
Squamous cell carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 2001, Mar-15, Volume: 49, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Analysis of Variance; Antineoplastic Combined Chemothera

2001
[Two cases of squamous cell carcinoma of the anal canal treated with chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

2001
Metastatic in-situ perianal Paget's disease.
    Journal of the Royal Society of Medicine, 2001, Volume: 94, Issue:3

    Topics: Abdomen; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Fluorourac

2001
The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy.
    International journal of radiation oncology, biology, physics, 2001, Jul-01, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2001
Impaired sphincter function and good quality of life in anal carcinoma patients after radiotherapy: a paradox?
    Frontiers of radiation therapy and oncology, 2002, Volume: 37

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colostomy; Combined Moda

2002
Radiochemotherapy for anal carcinoma - effectivity and late toxicity.
    Onkologie, 2002, Volume: 25, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2002
Extramammary Paget's disease.
    Canadian Medical Association journal, 1978, Jan-21, Volume: 118, Issue:2

    Topics: Aged; Anus Neoplasms; Fluorouracil; Genital Neoplasms, Male; Humans; Male; Paget Disease, Extramamma

1978
Carcinoma of the anus treated with a combination of radiotherapy and chemotherapy.
    Cancer treatment reports, 1979, Volume: 63, Issue:3

    Topics: Adult; Anus Neoplasms; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Hu

1979
[Practice in the treatment of rectal carcinoma. Recommendations of the Deutschen Gesellschaft für Chirurgie].
    Medizinische Klinik, 1977, Dec-02, Volume: 72, Issue:48

    Topics: Anus Neoplasms; Female; Fluorouracil; Germany, West; Humans; Intestinal Polyps; Male; Neoplasm Metas

1977
Multidisciplinary preoperative approach to the management of epidermoid carcinoma of the anus and anorectum.
    Diseases of the colon and rectum, 1978, Volume: 21, Issue:2

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Middle Ag

1978
Squamous-cell carcinoma of the anus arising in a giant condyloma acuminatum: report of a case.
    Diseases of the colon and rectum, 1975, Volume: 18, Issue:2

    Topics: Administration, Topical; Anal Canal; Anus Diseases; Anus Neoplasms; Carcinoma, Squamous Cell; Condyl

1975
Multi-modality therapy for epidermoid carcinoma of the anus.
    Cancer, 1976, Volume: 37, Issue:1

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lung Neoplasms; Male; Middle

1976
Combined radiation and chemotherapy for epidermoid carcinoma of the anal canal.
    International journal of colorectal disease, 1992, Volume: 7, Issue:4

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorourac

1992
Induction chemotherapy with carboplatin and 5-fluorouracil in combination with radiotherapy in loco-regionally advanced epidermoid carcinoma of the anus--preliminary results.
    International journal of colorectal disease, 1992, Volume: 7, Issue:3

    Topics: Adult; Aged; Anus Neoplasms; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female;

1992
[Treatment of advanced anal cancer].
    Nordisk medicin, 1992, Volume: 107, Issue:8-9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Comb

1992
[Transanorectal ultrasonography in the evaluation of extension and the monitoring of epidermoid cancers of the anus treated by radiation or chemotherapy].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1992
Combined chemoradiation therapy for anal cancer. A report of 56 cases.
    Annals of surgery, 1992, Volume: 215, Issue:2

    Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols;

1992
Treatment of genital condylomata with topical 5-fluorouracil.
    Dermatologic clinics, 1991, Volume: 9, Issue:2

    Topics: Administration, Topical; Anus Neoplasms; Combined Modality Therapy; Condylomata Acuminata; Female; F

1991
Squamous cell carcinoma of the anal canal.
    American journal of surgery, 1991, Volume: 162, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

1991
[Radiotherapy of epidermoid cancers of the anal canal].
    Annales de gastroenterologie et d'hepatologie, 1991, Volume: 27, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Carcinoma, Squamous Cell;

1991
Androscopy for anogenital HPV.
    The Journal of family practice, 1991, Volume: 33, Issue:2

    Topics: Acetates; Acetic Acid; Adult; Anus Neoplasms; Cryosurgery; Female; Fluorouracil; Genital Neoplasms,

1991
[Carcinomas of the anal canal. Chemotherapy].
    Annales de gastroenterologie et d'hepatologie, 1991, Volume: 27, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Clinical Protocols; Combined M

1991
The force of change in the management of squamous-cell cancer of the anal canal.
    Diseases of the colon and rectum, 1991, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1991
[The therapeutic results and early and late toxicities of the treatment of anal canal carcinoma by radiotherapy or chemoradiotherapy].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1991, Volume: 167, Issue:8

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combine

1991
Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1991
Anal cancer: radiation and concomitant continuous infusion chemotherapy.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fluoroura

1991
Effectiveness of combined radio-chemotherapy in the management of epidermoid carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 1990, Volume: 19, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Combined M

1990
Perianal Paget's disease: successful treatment with combined chemoradiotherapy. Report of a case.
    Diseases of the colon and rectum, 1990, Volume: 33, Issue:2

    Topics: Aged; Anus Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Male; Mitomycin; Mitomycins;

1990
Thrombogenicity of intravenous 5-fluorouracil alone or in combination with cisplatin.
    Cancer, 1990, Feb-15, Volume: 65, Issue:4

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Fibrinogen; Fibrinopeptide A; Fluo

1990
Low dose, continuous infusion 5-fluorouracil plus radiotherapy for anal cancer.
    International journal of radiation oncology, biology, physics, 1990, Volume: 18, Issue:3

    Topics: Anus Neoplasms; Combined Modality Therapy; Fluorouracil; Humans

1990
[Current status of chemotherapy for colonic, rectal and anal carcinoma].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1990, Jul-17, Volume: 79, Issue:29-30

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colonic Neoplasms; Combi

1990
[Effects of intra-arterial infusion chemotherapy in local recurrence of anal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Carcinoma, Squamous Cell;

1989
[Buschke-Lowenstein tumor of the anal area].
    Annales de dermatologie et de venereologie, 1989, Volume: 116, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bleomycin; Cisplatin; Condylomata Ac

1989
Epidermoid carcinoma of the anal canal. Results of treatment by combined chemotherapy and radiation therapy.
    Diseases of the colon and rectum, 1989, Volume: 32, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1989
Primary treatment of carcinoma of the anus by combined radiotherapy and chemotherapy.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:10

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma; Combined Modality Therapy; Female; Fluorouracil; Follow-Up S

1989
[Anal canal carcinoma: diagnosis--therapy--prognosis].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Female; F

1989
[Anal neoplasms. Treatment with radiotherapy and exclusive chemotherapy].
    Revista medica de Chile, 1989, Volume: 117, Issue:10

    Topics: Aged; Anus Neoplasms; Carcinoma; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Midd

1989
Combination of cisplatin plus fluoropyrimidine chemotherapy effective against liver metastases from carcinoma of the anal canal.
    The American journal of medicine, 1989, Volume: 87, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

1989
Radiotherapy for anal cancer: experience from 1979-1987.
    International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Transitional Ce

1989
Definitive irradiation and chemotherapy for radiosensitization in management of anal carcinoma: interim report on Radiation Therapy Oncology Group study no. 8314.
    Journal of the National Cancer Institute, 1989, Jun-07, Volume: 81, Issue:11

    Topics: Anal Canal; Anus Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cobalt Radioisot

1989
Perianal Paget's disease. Report of three cases.
    Diseases of the colon and rectum, 1988, Volume: 31, Issue:6

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anus Neoplasms; Female; Fluorouracil; Humans; Male; Neoplas

1988
Combined preoperative neoadjuvant radiotherapy and chemotherapy for anal and rectal cancer.
    American journal of surgery, 1986, Volume: 151, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squ

1986
Clinical evidence of feasibility and efficacy of simultaneous irradiation and chemotherapy in advanced squamous cell carcinoma.
    Progress in clinical and biological research, 1986, Volume: 216

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachytherapy; Carcinom

1986
[Combined radio- and chemotherapy of anal cancer].
    Wiener klinische Wochenschrift, 1986, May-30, Volume: 98, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Colo

1986
[Radiotherapy and chemotherapy in anal carcinoma].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1987, Jan-10, Volume: 107, Issue:1

    Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorourac

1987
Feasibility of non-surgical definitive management of anal canal carcinoma.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1987
Preoperative chemotherapy and radiotherapy in the management of epidermoid carcinoma of the anal canal.
    Tumori, 1987, Apr-30, Volume: 73, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma,

1987
Definitive combined modality therapy of carcinoma of the anus. A report of 30 cases including results of salvage therapy in patients with residual disease.
    Diseases of the colon and rectum, 1987, Volume: 30, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

1987
[Function-preserving treatment of anal cancer using simultaneous radio- and chemotherapy].
    Deutsche medizinische Wochenschrift (1946), 1987, Jul-31, Volume: 112, Issue:31-32

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Carcinoma,

1987
Preoperative radio-chemotherapy in anal carcinoma.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 110

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Basal Cell; Carcino

1988
[Cutaneous metastasis of a cloacogenic tumor].
    Medicina cutanea ibero-latino-americana, 1987, Volume: 15, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Transitional Cell;

1987
[Etretinate and 5-fluorouracil in intra-anal Bowen's disease].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1986, Volume: 37, Issue:5

    Topics: Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bowen's Disease;

1986
Cisplatin plus 5-fluorouracil in the treatment of metastatic anal squamous cell carcinoma: a report of two cases.
    Cancer treatment reports, 1986, Volume: 70, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

1986
Cancer of the anal canal. Model for preoperative adjuvant combined modality therapy.
    The American journal of medicine, 1985, Volume: 78, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

1985
Treatment of anal canal carcinoma.
    Cancer, 1985, May-01, Volume: 55, Issue:9 Suppl

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brachyt

1985
The use of radiation therapy combined with chemotherapy in the management of squamous cell carcinoma of the anus and marginally resectable adenocarcinoma of the rectum.
    International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:9

    Topics: Aged; Antibiotics, Antineoplastic; Anus Neoplasms; Carcinoma, Squamous Cell; Combined Modality Thera

1985
Anorectal squamous cell carcinoma at Mississippi Baptist Medical Center: results of the last five years of the Nigro schedule.
    Journal of the Mississippi State Medical Association, 1985, Volume: 26, Issue:10

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; C

1985
Treatment of epidermoid carcinoma of the anal canal.
    Surgery, gynecology & obstetrics, 1985, Volume: 161, Issue:6

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma,

1985
Intra-arterial combined cancer chemotherapy in technically inoperable carcinoma of the anus and rectum.
    Acta chirurgica Scandinavica, 1974, Volume: 140, Issue:5

    Topics: Aged; Animals; Anus Neoplasms; Daunorubicin; Depression, Chemical; Dogs; Drug Therapy, Combination;

1974