Page last updated: 2024-08-24

imiquimod and Anal Cancer

imiquimod has been researched along with Anal Cancer in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (35.00)	29.6817
2010's	23 (57.50)	24.3611
2020's	3 (7.50)	2.80

Authors

Authors	Studies
Bassukas, ID; Dounousi, E; Gaitanis, G; Koutlas, V; Pappas, C; Tsironi, T	1
Bastida, C; Blanco, JL; Cranston, RD; Fuertes, I; Lopez-Cabezas, C; Mallolas, J; Ordi, J; Rodríguez-Carunchio, L	1
Marino, F	1
Brogden, DRL; Kontovounisios, C; Mills, SC; Pellino, G; Tekkis, P; Walsh, U	1
Baldelli, F; Cavazzoni, E; Leo, CA; Santorelli, C	1
Baker, JR; Brand, RM; Cranston, RD; Janocko, L; McGowan, I; Siegel, A	1
De Troya-Martín, M; Escudero-Santos, IM; Fernández-Morano, MT; Padilla-España, L; Repiso-Jiménez, JB; Rivas-Ruiz, F; Salas-Márquez, C	1
Eberhardt, J; Gray, A; Gray, J; Mudaliar, K; Swan, J; Tung, R	1
Boesecke, C; Kalff, JC; Pantelis, D; Rockstroh, J; Schwarze-Zander, C; Stoffels, B; Vilz, TO; Websky, MWV; Wesselmann, PC	1
Bonafé, GA; Dos Santos, JS; Kanno, DT; Martinez, CAR; Ortega, MM; Pereira, JA	1
Corbett, A; Kermode, AG; Reddel, SW; Triplett, J	1
Kreuter, A; Wieland, U	1
de Vries, HJ; Dijkgraaf, MG; Prins, JM; Richel, O; van Noesel, CJ	1
Bejarano, PA; Berho, M; Boutros, M	1
Champagne, BJ; Crawshaw, BP; Delaney, CP; Marderstein, EL; Reynolds, HL; Russ, AJ; Stein, SL	1
den Hollander, JC; van der Ende, ME; van der Snoek, EM	1
Dunne, EF; Introcaso, C; Park, IU	1
Delforge, M; DeWit, S; Feoli, F; Libois, A; Nkuize, M; Willems, N	1
Kreuter, A	1
Arechavala, RS; García-Río, I; González, LC; González-Pérez, R; Michelena, IA; Murua, AA; Santarén, BC; Urra, IT	1
Mahto, M; Nathan, M; O'Mahony, C	1
Lee, PK; Wilkins, KB	1
Barton, SE; Bower, M; Dixon, G; Fox, PA; Francis, N; Nathan, M; Singh, N; Weir, J	1
Heine, M; Sachse, MM; Wagner, G	1
Gormley, RH; Kovarik, CL	1
Fox, PA	1
Mengjun, B; Tasleem, MM; Zheng-Qiang, W	1
Balaguer, A; Barberà, MJ; Macaya, A; Muñoz-Santos, C	1
Altmeyer, P; Brockmeyer, NH; Conant, MA; Hochdorfer, B; Kreuter, A; Stücker, M; Weiland, U	1
Aubin, F; Drobacheff-Thiebaut, C; Laurent, R; Mougin, C; Pelletier, F; Venier, AG	1
Costa, RR; de Freitas, VG; de Góis, NM; Kesselring, F; Kobata, MP; Ribalta, JC; Taha, NS	1
Alfaro-Rubio, A; Botella, R; Guillén, C; Hueso, L; Llombart, B; Nagore, E; Requena, C; Sanmartín, O; Serra, C	1
Bower, M; Dancey, G; Stebbing, J	1
Altmeyer, P; Brockmeyer, NH; Hochdorfer, B; Kreuter, A; Pfister, H; Stücker, M; Swoboda, J; Weissenborn, SJ; Wieland, U	1
Altmeyer, P; Brockmeyer, NH; Gambichler, T; Kreuter, A; Pfister, H; Potthoff, A; Racz, P; Tenner-Racz, K; Wieland, U	1
Correa, LA; He, Q; Herrera, S; Rady, PL; Sanclemente, G; Tyring, SK; Wolff, JC; Zuleta, JJ	1
Altmeyer, P; Brockmeyer, NH; Gambichler, T; Kreuter, A; Pfister, H; Potthoff, A; Stücker, M; Swoboda, J; Wieland, U	1
Pehoushek, J; Smith, KJ	1
Gollnick, HP; Law, C; Marini, M; O'Mahony, C	1
Brodersen, JP; Gutzmer, R; Kapp, A; Kaspari, M; Kiehl, P; Vogelbruch, M; Werfel, T	1

Reviews

9 review(s) available for imiquimod and Anal Cancer

Article	Year
Evaluating the efficacy of treatment options for anal intraepithelial neoplasia: a systematic review. International journal of colorectal disease, 2021, Volume: 36, Issue:2 Topics: Anus Neoplasms; Carcinoma in Situ; Carcinoma, Squamous Cell; HIV Infections; Humans; Imiquimod; Neoplasm Recurrence, Local; Papillomavirus Infections	2021
Anal squamous intraepithelial neoplasia. Gastroenterology clinics of North America, 2013, Volume: 42, Issue:4 Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Antimetabolites, Antineoplastic; Anus Neoplasms; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorouracil; Humans; Imiquimod; Papillomavirus Infections; Papillomavirus Vaccines; Photochemotherapy; Watchful Waiting	2013
Human Papillomavirus and Genital Warts: A Review of the Evidence for the 2015 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Dec-15, Volume: 61 Suppl 8 Topics: Adolescent; Aminoquinolines; Antiviral Agents; Anus Neoplasms; Centers for Disease Control and Prevention, U.S.; Condylomata Acuminata; Female; HIV Infections; Humans; Imiquimod; Male; Papillomavirus Infections; Papillomavirus Vaccines; Practice Guidelines as Topic; Prevalence; United States; Young Adult	2015
More than a decade on: review of the use of imiquimod in lower anogenital intraepithelial neoplasia. International journal of STD & AIDS, 2010, Volume: 21, Issue:1 Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aged; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; Female; HIV Infections; Humans; Imiquimod; Male; Middle Aged; Penile Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome; Vulvar Neoplasms	2010
Condyloma and other infections including human immunodeficiency virus. The Surgical clinics of North America, 2010, Volume: 90, Issue:1 Topics: Aminoquinolines; Anti-Bacterial Agents; Antineoplastic Agents; Anus Neoplasms; Chancroid; Condylomata Acuminata; Female; Genital Diseases, Female; Genital Diseases, Male; Herpes Genitalis; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV Infections; Humans; Imiquimod; Male; Penicillin G; Proctitis; Rectal Diseases; Sexually Transmitted Diseases; Syphilis; Ulcer	2010
Human papillomavirus-related genital disease in the immunocompromised host: Part II. Journal of the American Academy of Dermatology, 2012, Volume: 66, Issue:6 Topics: Adjuvants, Immunologic; Alphapapillomavirus; Aminoquinolines; Antineoplastic Agents, Phytogenic; Antiviral Agents; Anus Neoplasms; Buschke-Lowenstein Tumor; Catechin; Caustics; Cidofovir; Condylomata Acuminata; Counseling; Cryotherapy; Cytosine; Female; Humans; Imiquimod; Immunocompromised Host; Male; Ointments; Organophosphonates; Papillomavirus Infections; Penile Neoplasms; Podophyllotoxin; Precancerous Conditions; Treatment Outcome; Trichloroacetic Acid; Vaginal Neoplasms; Vulvar Neoplasms; Warts	2012
Treatment options for anal intraepithelial neoplasia and evidence for their effectiveness. Sexual health, 2012, Volume: 9, Issue:6 Topics: Adult; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Anus Neoplasms; Cidofovir; Comorbidity; Cytosine; Female; Fluorouracil; Global Health; HIV Infections; Homosexuality, Male; Humans; Imiquimod; Incidence; Male; Organophosphonates; Papillomavirus Infections; Precancerous Conditions; Trichloroacetic Acid	2012
Extramammary Paget's disease of the perianal region: a review of the literature emphasizing management. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:1 Pt 1 Topics: Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Humans; Imiquimod; Paget Disease, Extramammary; Photochemotherapy; Skin Neoplasms	2013
Interventions for anal canal intraepithelial neoplasia. The Cochrane database of systematic reviews, 2012, Dec-12, Volume: 12 Topics: Aminoquinolines; Anal Canal; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; Humans; Imiquimod; Precancerous Conditions; Randomized Controlled Trials as Topic	2012

Trials

5 trial(s) available for imiquimod and Anal Cancer

Article	Year
Comparison of imiquimod, topical fluorouracil, and electrocautery for the treatment of anal intraepithelial neoplasia in HIV-positive men who have sex with men: an open-label, randomised controlled trial. The Lancet. Oncology, 2013, Volume: 14, Issue:4 Topics: Aminoquinolines; Anus Neoplasms; Carcinoma in Situ; Electrocoagulation; Fluorouracil; HIV; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Imiquimod; Male; Middle Aged; Netherlands; Papillomaviridae; Prospective Studies	2013
A double-blind, randomized controlled trial of the use of imiquimod cream for the treatment of anal canal high-grade anal intraepithelial neoplasia in HIV-positive MSM on HAART, with long-term follow-up data including the use of open-label imiquimod. AIDS (London, England), 2010, Sep-24, Volume: 24, Issue:15 Topics: Administration, Cutaneous; Adult; Aminoquinolines; Antiretroviral Therapy, Highly Active; Anus Neoplasms; Carcinoma, Squamous Cell; Double-Blind Method; HIV Infections; HIV-1; Homosexuality, Male; Humans; Imiquimod; Male	2010
[Effects of imiquimod on latent human papillomavirus anal infection in HIV-infected patients]. Annales de dermatologie et de venereologie, 2004, Volume: 131, Issue:11 Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aminoquinolines; Anus Diseases; Anus Neoplasms; Carcinoma; Double-Blind Method; Female; HIV Infections; Humans; Imiquimod; Male; Middle Aged; Papillomavirus Infections; Prospective Studies; Risk Factors	2004
Imiquimod treatment of anal intraepithelial neoplasia in HIV-positive men. Archives of dermatology, 2006, Volume: 142, Issue:11 Topics: Administration, Cutaneous; Adult; Aged; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; DNA, Viral; HIV Infections; Homosexuality, Male; Humans; Imiquimod; Male; Middle Aged; Papillomaviridae; Papillomavirus Infections; Pilot Projects; Polymerase Chain Reaction; Prospective Studies; Suppositories; Treatment Outcome	2006
Human papillomavirus (HPV) viral load and HPV type in the clinical outcome of HIV-positive patients treated with imiquimod for anogenital warts and anal intraepithelial neoplasia. Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:8 Topics: Adjuvants, Immunologic; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Aminoquinolines; Anus Diseases; Anus Neoplasms; Carcinoma in Situ; Condylomata Acuminata; Genital Diseases, Male; Humans; Imiquimod; Male; Middle Aged; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Treatment Outcome; Viral Load	2007

Other Studies

26 other study(ies) available for imiquimod and Anal Cancer

Article	Year
Immunocryosurgery is a safe and feasible treatment for basal cell carcinoma and Bowen disease in renal transplant recipients. Dermatologic therapy, 2022, Volume: 35, Issue:5 Topics: Aged; Anus Neoplasms; Bowen's Disease; Carcinoma, Basal Cell; Female; Humans; Imiquimod; Kidney Transplantation; Male; Middle Aged; Skin Neoplasms	2022
The effectiveness and tolerability of imiquimod suppositories to treat extensive intra-anal high-grade squamous intraepithelial lesions/warts in HIV-infected individuals. International journal of STD & AIDS, 2019, Volume: 30, Issue:12 Topics: Adjuvants, Immunologic; Administration, Rectal; Anal Canal; Anus Neoplasms; Condylomata Acuminata; Female; HIV Infections; Humans; Imiquimod; Male; Papillomaviridae; Papillomavirus Infections; Squamous Intraepithelial Lesions; Suppositories; Treatment Outcome; Warts	2019
Complete healing of perianal giant condyloma (buschke-löwenstein tumor) with imiquimod 5% cream alone. Techniques in coloproctology, 2020, Volume: 24, Issue:12 Topics: Anus Neoplasms; Buschke-Lowenstein Tumor; Condylomata Acuminata; Humans; Imiquimod; Perineum	2020
Response to imiquimod 5% cream as treatment for condyloma and anal intraepithelial neoplasia in HIV-positive and HIV-negative patients. Sexually transmitted infections, 2017, Volume: 93, Issue:3 Topics: Administration, Topical; Adult; Aminoquinolines; Anal Canal; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; Condylomata Acuminata; HIV Infections; Humans; Imiquimod; Italy; Male; Neoplasm Recurrence, Local; Retrospective Studies; Treatment Outcome	2017
A Pilot Study of the Immunologic, Virologic, and Pathologic Consequences of Intra-anal 5% Imiquimod in HIV-1-Infected Men With High-Grade Squamous Intraepithelial Lesions. Diseases of the colon and rectum, 2018, Volume: 61, Issue:3 Topics: Adult; Aminoquinolines; Anal Canal; Anus Neoplasms; Carcinoma in Situ; Cytokines; HIV Infections; HIV-1; Humans; Imiquimod; Male; Papillomavirus Infections; Pilot Projects; Prospective Studies	2018
Imiquimod anal tampons treatment of anal intraepithelial neoplasia. Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:8 Topics: Administration, Rectal; Adult; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; Female; Humans; Imiquimod; Male; Middle Aged; Retrospective Studies; Tampons, Surgical; Treatment Outcome	2018
Perianal extramammary Paget disease treated with topical imiquimod and oral cimetidine. Cutis, 2018, Volume: 101, Issue:4 Topics: Administration, Oral; Administration, Topical; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Cimetidine; Female; Humans; Imiquimod; Immunologic Factors; Middle Aged; Mohs Surgery; Paget Disease, Extramammary	2018
[Treatment of HPV-associated Anal Lesions in HIV-positive Patients - Comparison of Surgical Treatment and Topical Therapy with Imiquimod]. Zentralblatt fur Chirurgie, 2019, Volume: 144, Issue:4 Topics: Adult; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; HIV; HIV Infections; Humans; Imiquimod; Middle Aged; Papillomaviridae; Papillomavirus Infections; Retrospective Studies	2019
Rare perianal extramammary Paget disease successfully treated using topical Imiquimod therapy. BMC cancer, 2018, Sep-25, Volume: 18, Issue:1 Topics: Administration, Topical; Aged; Antineoplastic Agents; Anus Neoplasms; Biomarkers, Tumor; Biopsy; Humans; Imiquimod; Immunohistochemistry; Male; Paget Disease, Extramammary; Treatment Outcome	2018
Warts and all: Fingolimod and unusual HPV-associated lesions. Multiple sclerosis (Houndmills, Basingstoke, England), 2019, Volume: 25, Issue:11 Topics: Ankle; Antineoplastic Agents; Anus Neoplasms; Carcinoma, Squamous Cell; Cryotherapy; Fingers; Fingolimod Hydrochloride; Foot Dermatoses; Hand Dermatoses; Humans; Imiquimod; Immunosuppressive Agents; Lymphopenia; Multiple Sclerosis, Relapsing-Remitting; Papillomavirus Infections; Warts	2019
One step towards standardised management of anal dysplasia. The Lancet. Oncology, 2013, Volume: 14, Issue:4 Topics: Aminoquinolines; Anus Neoplasms; Electrocoagulation; Fluorouracil; Homosexuality, Male; Humans; Imiquimod; Male	2013
High-resolution anoscopy or expectant management for anal intraepithelial neoplasia for the prevention of anal cancer: is there really a difference? Diseases of the colon and rectum, 2015, Volume: 58, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Anus Diseases; Anus Neoplasms; Biopsy; Combined Modality Therapy; Female; Humans; Imiquimod; Male; Middle Aged; Precancerous Conditions; Proctoscopy; Retrospective Studies; Treatment Outcome	2015
Imiquimod 5% cream for five consecutive days a week in an HIV-infected observational cohort up to 32 weeks in the treatment of high-grade squamous intraepithelial lesions. Sexually transmitted infections, 2015, Volume: 91, Issue:4 Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Anal Canal; Antineoplastic Agents; Anus Neoplasms; Disease Progression; Electrocoagulation; Female; HIV Seropositivity; Humans; Imiquimod; Male; Neoplasm Recurrence, Local; Ointments; Papillomaviridae; Prospective Studies; Squamous Intraepithelial Lesions of the Cervix	2015
Treatment of anal dysplasia in HIV-positive men who have sex with men in a large AIDS reference centre. Acta clinica Belgica, 2017, Volume: 72, Issue:1 Topics: Adult; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; Feasibility Studies; HIV Infections; Humans; Imiquimod; Male; Middle Aged; Retrospective Studies; Treatment Outcome	2017
Imiquimod for vulvar intraepithelial neoplasia. The New England journal of medicine, 2008, Jul-03, Volume: 359, Issue:1 Topics: Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; Female; Humans; Imiquimod; Papillomaviridae; Papillomavirus Infections; Viral Load; Vulvar Neoplasms	2008
Coexisting perianal squamous cell carcinoma, Bowen's disease, and condylomata acuminata treated with topical imiquimod 5%. International journal of dermatology, 2008, Volume: 47, Issue:12 Topics: Administration, Topical; Aminoquinolines; Antineoplastic Agents; Anus Diseases; Anus Neoplasms; Bowen's Disease; Carcinoma, Squamous Cell; Condylomata Acuminata; Female; Humans; Imiquimod; Immunologic Factors; Middle Aged; Neoplasms, Multiple Primary; Skin Neoplasms	2008
[Extramammary Paget disease: successful therapy with imiquimod 5% cream]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2012, Volume: 63, Issue:1 Topics: Administration, Topical; Aged, 80 and over; Aminoquinolines; Anus Neoplasms; Dermatologic Agents; Female; Humans; Imiquimod; Paget Disease, Extramammary	2012
Treatment of anal intraepithelial neoplasia in patients with acquired HIV with imiquimod 5% cream. Journal of the American Academy of Dermatology, 2004, Volume: 50, Issue:6 Topics: Adjuvants, Immunologic; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; HIV Infections; Humans; Imiquimod; Male; Ointments	2004
Grade 3 vulvar and anal intraepithelial neoplasia in a HIV seropositive child--therapeutic result: case report. Clinical and experimental obstetrics & gynecology, 2005, Volume: 32, Issue:2 Topics: Administration, Topical; Aminoquinolines; Anti-HIV Agents; Anus Neoplasms; Carcinoma; Child; Combined Modality Therapy; Female; Follow-Up Studies; HIV Infections; HIV Seropositivity; Humans; Imiquimod; Immunocompromised Host; Low-Level Light Therapy; Papillomavirus Infections; Risk Assessment; Treatment Outcome; Vulvar Neoplasms	2005
[Perianal Bowen's disease treated with imiquimod]. Actas dermo-sifiliograficas, 2005, Volume: 96, Issue:7 Topics: Aged; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Bowen's Disease; Humans; Imiquimod; Male; Skin Neoplasms	2005
A tale of three Hs: HPV, HIV & HAART. Future oncology (London, England), 2006, Volume: 2, Issue:1 Topics: Aminoquinolines; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Anus Neoplasms; Female; HIV Infections; Humans; Imiquimod; Male; Mass Screening; Papillomaviridae; Papillomavirus Infections; Uterine Cervical Neoplasms; Viral Vaccines	2006
p16ink4a expression decreases during imiquimod treatment of anal intraepithelial neoplasia in human immunodeficiency virus-infected men and correlates with the decline of lesional high-risk human papillomavirus DNA load. The British journal of dermatology, 2007, Volume: 157, Issue:3 Topics: Administration, Cutaneous; Adult; AIDS-Related Opportunistic Infections; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Biomarkers, Tumor; Carcinoma in Situ; Cyclin-Dependent Kinase Inhibitor p16; DNA, Viral; Homosexuality, Male; Humans; Imiquimod; Ki-67 Antigen; Male; Papillomaviridae; Papillomavirus Infections; Pilot Projects; Precancerous Conditions; Viral Load	2007
Imiquimod leads to a decrease of human papillomavirus DNA and to a sustained clearance of anal intraepithelial neoplasia in HIV-infected men. The Journal of investigative dermatology, 2008, Volume: 128, Issue:8 Topics: Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Carcinoma in Situ; DNA, Viral; Follow-Up Studies; HIV Infections; Human papillomavirus 16; Human papillomavirus 18; Humans; Imiquimod; Longitudinal Studies; Male; Papillomaviridae; Prospective Studies; Treatment Outcome	2008
Imiquimod and 5% fluorouracil therapy for anal and perianal squamous cell carcinoma in situ in an HIV-1-positive man. Archives of dermatology, 2001, Volume: 137, Issue:1 Topics: Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma in Situ; Carcinoma, Squamous Cell; Drug Administration Schedule; Fluorouracil; HIV Infections; HIV-1; Humans; Imiquimod; Male; Middle Aged	2001
New patient-applied therapy for anogenital warts is rated favourably by patients. International journal of STD & AIDS, 2001, Volume: 12, Issue:9 Topics: Administration, Topical; Adolescent; Adult; Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Female; Follow-Up Studies; Genital Neoplasms, Female; Genital Neoplasms, Male; Health Knowledge, Attitudes, Practice; Humans; Imiquimod; Male; Surveys and Questionnaires; Time Factors; Treatment Outcome; Warts	2001
Successful treatment of anogenital Bowen's disease with the immunomodulator imiquimod, and monitoring of therapy by DNA image cytometry. The British journal of dermatology, 2002, Volume: 147, Issue:1 Topics: Aminoquinolines; Antineoplastic Agents; Anus Neoplasms; Bowen's Disease; Condylomata Acuminata; DNA, Viral; Drug Monitoring; Female; Humans; Image Cytometry; Imiquimod; Interferon Inducers; Middle Aged; Papillomaviridae; Skin Neoplasms; Vaginal Neoplasms	2002