Page last updated: 2024-11-04

suramin and Serum Sickness

suramin has been researched along with Serum Sickness in 1 studies

Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.

Serum Sickness: Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KESSLER, S1
SCHENCK, R1
SEITZ, W1

Other Studies

1 other study available for suramin and Serum Sickness

ArticleYear
[A serum lability reaction with germanin and its dependence on the albumin and alpha2-globulin content].
    Klinische Wochenschrift, 1952, Nov-01, Volume: 30, Issue:41-2

    Topics: Albumins; Alpha-Globulins; Humans; Liver Function Tests; Serum Sickness; Suramin

1952