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dipyridamole and Serum Sickness

dipyridamole has been researched along with Serum Sickness in 2 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Serum Sickness: Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.

Research Excerpts

ExcerptRelevanceReference
"In the acute serum sickness model in rabbits, we investigated platelet release of 5-HT, platelet surface immunoglobulins, and platelet aggregation in response to ADP, together with the effect of dipyridamole and the Clr antagonist FUT-175."7.67Platelet involvement in the nephritis of acute serum sickness in rabbits: protection by dipyridamole and FUT-175. ( Cameron, JS; Inage, H; Koyama, A; Narita, M; Neild, GH; Sano, M; Tojo, S, 1985)
"In the acute serum sickness model in rabbits, we investigated platelet release of 5-HT, platelet surface immunoglobulins, and platelet aggregation in response to ADP, together with the effect of dipyridamole and the Clr antagonist FUT-175."3.67Platelet involvement in the nephritis of acute serum sickness in rabbits: protection by dipyridamole and FUT-175. ( Cameron, JS; Inage, H; Koyama, A; Narita, M; Neild, GH; Sano, M; Tojo, S, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagamatsu, T1
Suzuki, Y1
Koyama, A1
Inage, H1
Sano, M1
Narita, M1
Tojo, S1
Neild, GH1
Cameron, JS1

Other Studies

2 other studies available for dipyridamole and Serum Sickness

ArticleYear
Antinephritic effect of prostaglandin E1 on serum sickness nephritis in rats (4). Enhanced clearance of macromolecules by the reticulo-endothelial system with prostaglandin E1.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:3

    Topics: Animals; Antigen-Antibody Complex; Azathioprine; Carbon; Dipyridamole; Male; Mononuclear Phagocyte S

1987
Platelet involvement in the nephritis of acute serum sickness in rabbits: protection by dipyridamole and FUT-175.
    Clinical and experimental immunology, 1985, Volume: 61, Issue:2

    Topics: Adenosine Diphosphate; Animals; Antigen-Antibody Complex; Benzamidines; Blood Platelets; Cell Surviv

1985